Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Cephalotus follicularis
Species name
Cephalotus follicularis is a species of eudicot in the family Cephalotaceae.
Species info
Gene sequence info
Cephalotus_follicularis.COMT.fa
Download
>Cfol_v3_16751
MGSTGEETQMTPTQVSDEEAKLFAMQLASASVLPMILKAALELDLLEIMAKAGPGAFMSPADISSQLPTKNPDAPVMLDRILRLLASYSVLTYSLRTLPDGNVQRLYGLAPVCKFLTKNEDGVSIAALCLMNQDKVLMESWYYLKDAVLEGGIPFNKAYGMTAFEYHGTDPRFNKVFNRGMSDHSTITMKKLLEIYKGFEGLKSLVDVGGGTGAVINMIVSKYPSIKGINFDLPHVIEDAPSYPGVQHVGGDMFSSVPKADAIFMKWICHDWSDAHCLKFLKNCYEALPDNGKVIVAECILPVAPDPSLATKGVIHIDCIMLAHNPGGKERTEKEFEALAKDAGFQGFKVICSALNTYVMEFQKQA
>Cfol_v3_22453
MALSAETHSIVNEENMEEESYAYAMQLVSSLVLPMTLQAAIELGIFEIIAKAGPDAKLSASEIGAQMSTENPDALVMLERILRLLASHCVLGCYVVDYERLYSLAPVSKYFVINEDGVSLGPLMALLHDKVFLDSWSQLKGAIVEGGIAFDMVHGTNAFEYPGLDPRFNQLFNTAMYNHTSVVIKRILKSYKGFANLKQLVDVGGGLGVTLKAITCKYPNLKGINFDLPHVIQHAHPYPGVEHVGGDMFENVPNGDAVFMKWILHDWSDEHCLKLLKNCYNAIPDDGKVIVVEAVLPIMPETNHAAKSSSQMDVLMMTQNPGGKERTRQEFMALATVAGFSGITYESFACNFWVMEFFK
>Cfol_v3_22496
MHVTSMDGHSGCPTSLFSKLCLLRVGNILFASINNRSVLLVSEGAMGTNSIQYTLPKLSQVDDEDEAFAYAMYLRTSATLVNVLNAALELGLLDIIARAGPGAQLSPSEVVSHLPTNNPQATSLVDRMFRLLTCHSLLSCTLKTLEDGSVTRVYGLTLAGRVFTNREDGRTMASFKFQKAMEVVWFDLKDLVLEGGDLFEKVHGLTIYDYMSQNPDMSSNFNKAMGDLSKITMTKVLDAYKGFEGLTSLVDVGGGVGTTLKIILSKYPSIQGINLDEPHVILNAPPFPGITHVGGDMFKSVPNGNAIIMKNILHNWGDEDCIKILRNCYDALPKNGKVIVLSWILTEEPESSIASKYVSHMDIIMCMHPGGRQRTESEFRALSKAAGFSHFQVDCYAYHVGIMELHK
>Cfol_v3_02443
MSFNANLTDLFIRIRSQSPKKKKIIFIVCVIWQWILTTWTDDECKVIIQNCYKALPVGGKLIACEPVLPKESDDSHRTRALLEGDIFVMTIYRAKGKHRTQEEFKQLGLSVGFPHFRAFHIDYFYTVLEFQK
>Cfol_v3_26164
MGKPQQTNPNSMTQDHDQEQEVSKLAIRLTNAVVLPMVLKSALELNLLDTISAAGDGAFLSPSELASQLSTKNPDAAILLDRMLRLLASYDILKCSLRTGEDGGAERSYGAGPLCKFFARNQDGGSVADMFLFHHDKVMIESWYHLNDAVLEGGIPFNRAHGMSLFEYPGLDERFNRLLNQAMSSFSTFTLKKLLDVYKGFDGTKVLVDVGGNSGITLRAITSMYPGIKGINFDLPHVLADAPTYSGVEHLEGDMFVSIPKGDTIFMKNIFHDWSDEHCVTILKNCWEALPYNGKVVNVECHLPVVPENNVTSHIAFSIDLYMFALTPGGKERTQEEFEALAVKSGFDYEVICSAYGFRVAEFHKKANA
>Cfol_v3_18595
MRTSINEEDNHAQYAMQLASASVLPMVLKATIELGVLDIINSAGPGALLSPSQIASMLPTKDNPDAPFMLDCILRLLASHSILTCSLVSEDHDSKVHRLYGLAPAAKYFIQNQDEGSLAPLINLIQDKTMLNIWYHLKDSVLEGGFPFNRAYGLSAFEYASKDSRFSEIFKCAMIDFNTLFMEKILVTYKGFEGLKSLVDVGGGNGSILQTIISKYPSIKGINYDLATVVENLPSYPGIVHVAGDMFKSIPKGFWFIKQWILHDWNDSNCIKILKNCYEALPANGKVIVVDMVIPEDPEANVAYRSLFQLYMFLMNMNIDRKERTQREYGSLAKEAGFSFIQVPSCAFNFSVVEFNKTM
>Cfol_v3_20771
MQLATSSIVPMLVKASIELNLLEIMSKPGPVALFAPSEIASQLPIQNPDGAVIIERLLRVLASYSILTCKFVTNKDGHNHRLYGLAPVCKYLVPNEDGISLAPFLLLSLDKTITDSCHCIKEAILEGGTPFDRAHGMHYFEYAERESKFRNLFNQAMYSHTSIIMKRILEIYKGFEGLNELVDVGGLGTNLISIVSKYPHLKGVNFDLPHVIKDAPSCPGVNHIAGNMFSSVPKGEVIFMKWILHDWNDDQCLKILNNCYALPKNGKVIIVESIVPEFPATDLVSKNTFKFDMGMFLANPGGKERTKKEIEALAIAAGFADSNAICLAYSYWVIEYYKIKI
>Cfol_v3_06469
MENKRCEEESSKSARLAIMELANMISVPMSLNAIVRLNVPDAMWQDGSNTPLSASQILTRVLPSGGGDPENLQRLLRMLTSYHVFEEHLIDGSDSERRYSLTQIGKTLVTDAQGLSYASYVLQHHQEELMRAWEVVQDAVVDPTTEPFVKANGEAAYSYYVRKPEMNGLMLKAMSGVSVPFMKAMLDGYDGFEGVETLVDVGGSAGDCLRMILHKHPAVRQGLNFDLPAVVAKVPTIPGEFIIIFEQFCDFNFRKFFFFLS
>Cfol_v3_25032
MGNPQQTNPNSMTQDHDQEQEVSKPAIRLTNAVVLPMVLKSALELNLLDTISAAGDGAFLSPSELASQLSTKNPDAAIVLDRMLRLLASYDILKCSLRTGEDGGVERSYGAGPLCKFFARNQDGGSVADMFLFLHDKVMIESWYHWNDAVLEGGIPFNRAHGMSLFEYPGQDQRFNRLLNQAMSSFSTFTLKKLLDVYKGFDGTKVLVDVGGNSGITLHAITSKYPGIKGINFDLPHVLADAPNYSGVEHLQGDMFVSVPKGDTIFIKNIFHDWSDEHCVTILKNCWEALPYNGKVVNVECHLPVVPENNVTSHTAFSIDLYMFALTPGGKERTQEEFEALAAKSGFGYEVICSAYGFRVAEFHKKARA
>Cfol_v3_15452
MTGAMDSTNQKINYKKRQVHGSIRQCQSRISHILQYNNEQSSNNASQKMCNPQQTHQNPMTQDHDQEQEGGTLAIRLAHLVALPMVLKSALELNLIDTIFTAGDGAFLSPSELASQLSTKNPDAPVLLDRMLRRLASYDILKCSLRAGENGEVERSYGAGPLCKFLAKNQDGGSVADFFLLHHDKVLMESWYHLNDVILEGGVPFNRAYGMTLFEYLGIDQRFNRLFNQAMSNPSTMIMKKMLDVYKGFEGTKVLVDVGGGIGATLDAIISKYPGIKGINFDLPHVLADAPTYSGVEHVGGDMFVSVPKGDTIFMKWILHAWSDERCLILLKNCWEALPNNGKVIVVDCILPVAPENNVTSHIAYEFDLFMLAVTPGGKERTQEEFKALALKSGFRGCQVECCAYDIGVLEFHKKAEA
MGSTGEETQMTPTQVSDEEAKLFAMQLASASVLPMILKAALELDLLEIMAKAGPGAFMSPADISSQLPTKNPDAPVMLDRILRLLASYSVLTYSLRTLPDGNVQRLYGLAPVCKFLTKNEDGVSIAALCLMNQDKVLMESWYYLKDAVLEGGIPFNKAYGMTAFEYHGTDPRFNKVFNRGMSDHSTITMKKLLEIYKGFEGLKSLVDVGGGTGAVINMIVSKYPSIKGINFDLPHVIEDAPSYPGVQHVGGDMFSSVPKADAIFMKWICHDWSDAHCLKFLKNCYEALPDNGKVIVAECILPVAPDPSLATKGVIHIDCIMLAHNPGGKERTEKEFEALAKDAGFQGFKVICSALNTYVMEFQKQA
>Cfol_v3_22453
MALSAETHSIVNEENMEEESYAYAMQLVSSLVLPMTLQAAIELGIFEIIAKAGPDAKLSASEIGAQMSTENPDALVMLERILRLLASHCVLGCYVVDYERLYSLAPVSKYFVINEDGVSLGPLMALLHDKVFLDSWSQLKGAIVEGGIAFDMVHGTNAFEYPGLDPRFNQLFNTAMYNHTSVVIKRILKSYKGFANLKQLVDVGGGLGVTLKAITCKYPNLKGINFDLPHVIQHAHPYPGVEHVGGDMFENVPNGDAVFMKWILHDWSDEHCLKLLKNCYNAIPDDGKVIVVEAVLPIMPETNHAAKSSSQMDVLMMTQNPGGKERTRQEFMALATVAGFSGITYESFACNFWVMEFFK
>Cfol_v3_22496
MHVTSMDGHSGCPTSLFSKLCLLRVGNILFASINNRSVLLVSEGAMGTNSIQYTLPKLSQVDDEDEAFAYAMYLRTSATLVNVLNAALELGLLDIIARAGPGAQLSPSEVVSHLPTNNPQATSLVDRMFRLLTCHSLLSCTLKTLEDGSVTRVYGLTLAGRVFTNREDGRTMASFKFQKAMEVVWFDLKDLVLEGGDLFEKVHGLTIYDYMSQNPDMSSNFNKAMGDLSKITMTKVLDAYKGFEGLTSLVDVGGGVGTTLKIILSKYPSIQGINLDEPHVILNAPPFPGITHVGGDMFKSVPNGNAIIMKNILHNWGDEDCIKILRNCYDALPKNGKVIVLSWILTEEPESSIASKYVSHMDIIMCMHPGGRQRTESEFRALSKAAGFSHFQVDCYAYHVGIMELHK
>Cfol_v3_02443
MSFNANLTDLFIRIRSQSPKKKKIIFIVCVIWQWILTTWTDDECKVIIQNCYKALPVGGKLIACEPVLPKESDDSHRTRALLEGDIFVMTIYRAKGKHRTQEEFKQLGLSVGFPHFRAFHIDYFYTVLEFQK
>Cfol_v3_26164
MGKPQQTNPNSMTQDHDQEQEVSKLAIRLTNAVVLPMVLKSALELNLLDTISAAGDGAFLSPSELASQLSTKNPDAAILLDRMLRLLASYDILKCSLRTGEDGGAERSYGAGPLCKFFARNQDGGSVADMFLFHHDKVMIESWYHLNDAVLEGGIPFNRAHGMSLFEYPGLDERFNRLLNQAMSSFSTFTLKKLLDVYKGFDGTKVLVDVGGNSGITLRAITSMYPGIKGINFDLPHVLADAPTYSGVEHLEGDMFVSIPKGDTIFMKNIFHDWSDEHCVTILKNCWEALPYNGKVVNVECHLPVVPENNVTSHIAFSIDLYMFALTPGGKERTQEEFEALAVKSGFDYEVICSAYGFRVAEFHKKANA
>Cfol_v3_18595
MRTSINEEDNHAQYAMQLASASVLPMVLKATIELGVLDIINSAGPGALLSPSQIASMLPTKDNPDAPFMLDCILRLLASHSILTCSLVSEDHDSKVHRLYGLAPAAKYFIQNQDEGSLAPLINLIQDKTMLNIWYHLKDSVLEGGFPFNRAYGLSAFEYASKDSRFSEIFKCAMIDFNTLFMEKILVTYKGFEGLKSLVDVGGGNGSILQTIISKYPSIKGINYDLATVVENLPSYPGIVHVAGDMFKSIPKGFWFIKQWILHDWNDSNCIKILKNCYEALPANGKVIVVDMVIPEDPEANVAYRSLFQLYMFLMNMNIDRKERTQREYGSLAKEAGFSFIQVPSCAFNFSVVEFNKTM
>Cfol_v3_20771
MQLATSSIVPMLVKASIELNLLEIMSKPGPVALFAPSEIASQLPIQNPDGAVIIERLLRVLASYSILTCKFVTNKDGHNHRLYGLAPVCKYLVPNEDGISLAPFLLLSLDKTITDSCHCIKEAILEGGTPFDRAHGMHYFEYAERESKFRNLFNQAMYSHTSIIMKRILEIYKGFEGLNELVDVGGLGTNLISIVSKYPHLKGVNFDLPHVIKDAPSCPGVNHIAGNMFSSVPKGEVIFMKWILHDWNDDQCLKILNNCYALPKNGKVIIVESIVPEFPATDLVSKNTFKFDMGMFLANPGGKERTKKEIEALAIAAGFADSNAICLAYSYWVIEYYKIKI
>Cfol_v3_06469
MENKRCEEESSKSARLAIMELANMISVPMSLNAIVRLNVPDAMWQDGSNTPLSASQILTRVLPSGGGDPENLQRLLRMLTSYHVFEEHLIDGSDSERRYSLTQIGKTLVTDAQGLSYASYVLQHHQEELMRAWEVVQDAVVDPTTEPFVKANGEAAYSYYVRKPEMNGLMLKAMSGVSVPFMKAMLDGYDGFEGVETLVDVGGSAGDCLRMILHKHPAVRQGLNFDLPAVVAKVPTIPGEFIIIFEQFCDFNFRKFFFFLS
>Cfol_v3_25032
MGNPQQTNPNSMTQDHDQEQEVSKPAIRLTNAVVLPMVLKSALELNLLDTISAAGDGAFLSPSELASQLSTKNPDAAIVLDRMLRLLASYDILKCSLRTGEDGGVERSYGAGPLCKFFARNQDGGSVADMFLFLHDKVMIESWYHWNDAVLEGGIPFNRAHGMSLFEYPGQDQRFNRLLNQAMSSFSTFTLKKLLDVYKGFDGTKVLVDVGGNSGITLHAITSKYPGIKGINFDLPHVLADAPNYSGVEHLQGDMFVSVPKGDTIFIKNIFHDWSDEHCVTILKNCWEALPYNGKVVNVECHLPVVPENNVTSHTAFSIDLYMFALTPGGKERTQEEFEALAAKSGFGYEVICSAYGFRVAEFHKKARA
>Cfol_v3_15452
MTGAMDSTNQKINYKKRQVHGSIRQCQSRISHILQYNNEQSSNNASQKMCNPQQTHQNPMTQDHDQEQEGGTLAIRLAHLVALPMVLKSALELNLIDTIFTAGDGAFLSPSELASQLSTKNPDAPVLLDRMLRRLASYDILKCSLRAGENGEVERSYGAGPLCKFLAKNQDGGSVADFFLLHHDKVLMESWYHLNDVILEGGVPFNRAYGMTLFEYLGIDQRFNRLFNQAMSNPSTMIMKKMLDVYKGFEGTKVLVDVGGGIGATLDAIISKYPGIKGINFDLPHVLADAPTYSGVEHVGGDMFVSVPKGDTIFMKWILHAWSDERCLILLKNCWEALPNNGKVIVVDCILPVAPENNVTSHIAYEFDLFMLAVTPGGKERTQEEFKALALKSGFRGCQVECCAYDIGVLEFHKKAEA
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University