Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Cephalotus follicularis
Species name
Cephalotus follicularis is a species of eudicot in the family Cephalotaceae.
Species info
Gene sequence info
Cephalotus_follicularis.4CL.fa
Download
>Cfol_v3_09999
MSMERSGYGRDGIYRSLRPSLVLPKDPNLSMVKHLFNNSSSFPHKPALIDVETNETLSFSQLKSTIIKLSHGFVHLGIKKNDVVLIFAPNSIQYPLCFLGIIAIGAIATTVNPVYTKNELGKQIKDSNPKLIITVHELHDKVKDFNIPVVLLGPKQQQSRDTHFDELVNLVGPVSDLPVVSVSQNDVAALLYSSGTTGVSKGVILTHKNFISASSMVTMDQKVAGELHNIFLCVLPMFHVFGLAVILYSQLQIGNAIVVLNKFDFMMMLKSMEKYRVTHLWLVPPIVLALAKQDVVKKFDLSSLKQIGSGAAPLGKDLMQDCAKNFPHATVMQGYGMTETCGIVSVENTFHGIRHTGSAGTLVAGVESQIISVDTLKPLPPNQLGEIWVRGPNMMRGYFNNPQATDLTIDKQGWVHTGDLGYFDEDGNLFVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDAEAGEVPIAYVVRAPKSSLTEEDIQKYIANQVAPYKRLRRVAFINSVPKSAAGKILRRELIDKVRSKI
>Cfol_v3_20014
HQLLTPITSTYLLSLLLLFITHTHTLFPSLTKPTHLKIFFLITLLLRSHTKLLFKHQKQIKMISIASVEPQKQDLSPNITSPNPSSETHIFRSKLEDIPISNHLPLHTYCFENLSDFSERPCLIVGSTGKVYSFAETHLICQKTAAGLSNLGIKKGDVIMILLHNCAEFVFSFMAASMIGAVSTTANPFYTSTEIFKQFNSARAKLIITQSQYVDKLRDTNENTPKIGEDFKVITIDDPPENCLHFTVLSEANENDTPTATIDPDDPVALPFSSGTTGLPKGVILTQKSLITSVAQQVDGENPNLYLTQEDVVLCVLPLFHIYSLNSVLLCSLRAGAAVLLMQKFEIGALLELIQTHKVSVAAVVPPLVLALAKNPMVAKFDLSSIRVVLSGAAPLGKELEEALRSRIPQAIFGQGYGMTEAGPVLSMCLAFAKQPFPTKSGSCGTVVRNAELKVIDPETGCSLGYNQPGEICIRGQQIMKGYLNDAEATAATIDIEGWLHTGDIGYVDDDDEVFIVDRVKEIIKFKGFQVPPAELEALLVSHPSIADAAVVSQKDEVAGEVPVAFVVRSNGFELTEVAVKEYIAKQVVFYKRLHKVHFVHAIPKSPSGKILRKDLRAKLTTTSLMP
>Cfol_v3_27126
MAINNTTKQQEIIYRSKLPDIYIPKHLPLHSYIFEKLSQHSTRPCLINGATGDVYTYAEVDLTARRVASGLNKLGIQQGDVIMILLQNSPEFVLSFLGASYRGAIATAANPFFTPAEIAKQVKASDARLIVTQACYSDKVKDLAQENDVKIMCIDSAPDGCLHFTELTQANENDIPNVDINPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGDNPNLYFHGEDVILCVLPMFHIYALNSIMLCGLRVGAAILIMQKFEINSLLELIQKYKITIAPMVPPIVLAIAKSPDVDKYDLSSIRMLKSGAASLGKELEDAVGAKFPNARLGQGYGMTEAGPVLTMCLSFAKEPFEITSGTCGTVVRNAEMKIVDPETGDSLPTNQRGEICIRGDQIMKGYLNDPEATKRTIDKDGWLHTGDIGYINENDELFIVDRLKELIKYKGFQVAPAELEAMLLCHPDITDAAVVGMKDDMAGEIPVAFVVRSNNSQITGDEIKQYISKQVVFYKRINRVFFVDVIPKAPSGKILRKDLRAKLESGNPN
>Cfol_v3_03126
MDPKQDDKEFIFRSKLPDIYIPNNLPLHSYCFQNISEFKDRPCVINGANGDIYSYAEVELASRKVASGLNKIGIQQGDVIMLLLPNCSEFVFAFLGASYLGAMSTTANPFYTPAEIAKQATASKAKVIVTQAAYAEKVRDFAEENGVRIITTDAPPENCMHFSELTQASEDEIPVIKIDPEEVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGDNPNLYFNKEDVILCVLPLFHIYSLNSVLLCALRVGAAILIMQKFEIIKMAELVEKYKVSIAPFVPPIVLAIAKSQDVDKYDLSSIRTVMSGAAPMGRELEDAFRAKLPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPETGSSLPRNQAGEICIRGSQIMKGYLNDPEATERTIDKDGWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEAMLIAHPTISDAAVVPMKDEGAGEVPVAFVVRANGSKIAEDEIKQYISKQVVFYKRINRVFFTDTIPKAPSGKILRKDLRAMLVAGVPNSS
>Cfol_v3_17010
MDPPLPYLSQDDEKEHIFRSRYPSVEVPVNMTLPNFVLHDAESYAEKVAFVEAVTGKSCTYGEVLRDTKRFAKALRSLGLRKGRVVVVLLPNIAEYGIVALGIMAAGGVFSGANPTAHASEIKKQVEVAGAQLIITNGANYEKVRGLELPVIVMGEERIDSAMNWDELLEAADCSSNNFVNEEVNQTDICALPFSSGTTGMSKGVMLTHRNLVANLCSTLFSVTPEMVGQVTILGLIPFFHIYGITGICCATLRNKGKVVVMNRFDLRTFLNALITQEVTFAPIVPPIILSLVKNPIVEEFDLSKLKLRAIMTAAAPLAPEILNAFENKFPGVQVQEAYGLTEHSCITLTHADPSKGHANAKKNSVGFILPNLEVKFIDPDNGQSLPKNTPGEICVRSQCVMKGYYNNEEETARTIDENGWLHTGDIGYIDDDGDIFIVDRIKELIKYKGFQVAPAELESILLSHPSVEDAAVVPLPDEEAGEIPAACVVMNKGAKESEEDIINFVGSSVASYKKVRVVQFVDAIPKSPSGKIMRRLLKDKIVERKAANSTTNSTFPK
MSMERSGYGRDGIYRSLRPSLVLPKDPNLSMVKHLFNNSSSFPHKPALIDVETNETLSFSQLKSTIIKLSHGFVHLGIKKNDVVLIFAPNSIQYPLCFLGIIAIGAIATTVNPVYTKNELGKQIKDSNPKLIITVHELHDKVKDFNIPVVLLGPKQQQSRDTHFDELVNLVGPVSDLPVVSVSQNDVAALLYSSGTTGVSKGVILTHKNFISASSMVTMDQKVAGELHNIFLCVLPMFHVFGLAVILYSQLQIGNAIVVLNKFDFMMMLKSMEKYRVTHLWLVPPIVLALAKQDVVKKFDLSSLKQIGSGAAPLGKDLMQDCAKNFPHATVMQGYGMTETCGIVSVENTFHGIRHTGSAGTLVAGVESQIISVDTLKPLPPNQLGEIWVRGPNMMRGYFNNPQATDLTIDKQGWVHTGDLGYFDEDGNLFVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDAEAGEVPIAYVVRAPKSSLTEEDIQKYIANQVAPYKRLRRVAFINSVPKSAAGKILRRELIDKVRSKI
>Cfol_v3_20014
HQLLTPITSTYLLSLLLLFITHTHTLFPSLTKPTHLKIFFLITLLLRSHTKLLFKHQKQIKMISIASVEPQKQDLSPNITSPNPSSETHIFRSKLEDIPISNHLPLHTYCFENLSDFSERPCLIVGSTGKVYSFAETHLICQKTAAGLSNLGIKKGDVIMILLHNCAEFVFSFMAASMIGAVSTTANPFYTSTEIFKQFNSARAKLIITQSQYVDKLRDTNENTPKIGEDFKVITIDDPPENCLHFTVLSEANENDTPTATIDPDDPVALPFSSGTTGLPKGVILTQKSLITSVAQQVDGENPNLYLTQEDVVLCVLPLFHIYSLNSVLLCSLRAGAAVLLMQKFEIGALLELIQTHKVSVAAVVPPLVLALAKNPMVAKFDLSSIRVVLSGAAPLGKELEEALRSRIPQAIFGQGYGMTEAGPVLSMCLAFAKQPFPTKSGSCGTVVRNAELKVIDPETGCSLGYNQPGEICIRGQQIMKGYLNDAEATAATIDIEGWLHTGDIGYVDDDDEVFIVDRVKEIIKFKGFQVPPAELEALLVSHPSIADAAVVSQKDEVAGEVPVAFVVRSNGFELTEVAVKEYIAKQVVFYKRLHKVHFVHAIPKSPSGKILRKDLRAKLTTTSLMP
>Cfol_v3_27126
MAINNTTKQQEIIYRSKLPDIYIPKHLPLHSYIFEKLSQHSTRPCLINGATGDVYTYAEVDLTARRVASGLNKLGIQQGDVIMILLQNSPEFVLSFLGASYRGAIATAANPFFTPAEIAKQVKASDARLIVTQACYSDKVKDLAQENDVKIMCIDSAPDGCLHFTELTQANENDIPNVDINPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGDNPNLYFHGEDVILCVLPMFHIYALNSIMLCGLRVGAAILIMQKFEINSLLELIQKYKITIAPMVPPIVLAIAKSPDVDKYDLSSIRMLKSGAASLGKELEDAVGAKFPNARLGQGYGMTEAGPVLTMCLSFAKEPFEITSGTCGTVVRNAEMKIVDPETGDSLPTNQRGEICIRGDQIMKGYLNDPEATKRTIDKDGWLHTGDIGYINENDELFIVDRLKELIKYKGFQVAPAELEAMLLCHPDITDAAVVGMKDDMAGEIPVAFVVRSNNSQITGDEIKQYISKQVVFYKRINRVFFVDVIPKAPSGKILRKDLRAKLESGNPN
>Cfol_v3_03126
MDPKQDDKEFIFRSKLPDIYIPNNLPLHSYCFQNISEFKDRPCVINGANGDIYSYAEVELASRKVASGLNKIGIQQGDVIMLLLPNCSEFVFAFLGASYLGAMSTTANPFYTPAEIAKQATASKAKVIVTQAAYAEKVRDFAEENGVRIITTDAPPENCMHFSELTQASEDEIPVIKIDPEEVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGDNPNLYFNKEDVILCVLPLFHIYSLNSVLLCALRVGAAILIMQKFEIIKMAELVEKYKVSIAPFVPPIVLAIAKSQDVDKYDLSSIRTVMSGAAPMGRELEDAFRAKLPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPETGSSLPRNQAGEICIRGSQIMKGYLNDPEATERTIDKDGWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEAMLIAHPTISDAAVVPMKDEGAGEVPVAFVVRANGSKIAEDEIKQYISKQVVFYKRINRVFFTDTIPKAPSGKILRKDLRAMLVAGVPNSS
>Cfol_v3_17010
MDPPLPYLSQDDEKEHIFRSRYPSVEVPVNMTLPNFVLHDAESYAEKVAFVEAVTGKSCTYGEVLRDTKRFAKALRSLGLRKGRVVVVLLPNIAEYGIVALGIMAAGGVFSGANPTAHASEIKKQVEVAGAQLIITNGANYEKVRGLELPVIVMGEERIDSAMNWDELLEAADCSSNNFVNEEVNQTDICALPFSSGTTGMSKGVMLTHRNLVANLCSTLFSVTPEMVGQVTILGLIPFFHIYGITGICCATLRNKGKVVVMNRFDLRTFLNALITQEVTFAPIVPPIILSLVKNPIVEEFDLSKLKLRAIMTAAAPLAPEILNAFENKFPGVQVQEAYGLTEHSCITLTHADPSKGHANAKKNSVGFILPNLEVKFIDPDNGQSLPKNTPGEICVRSQCVMKGYYNNEEETARTIDENGWLHTGDIGYIDDDGDIFIVDRIKELIKYKGFQVAPAELESILLSHPSVEDAAVVPLPDEEAGEIPAACVVMNKGAKESEEDIINFVGSSVASYKKVRVVQFVDAIPKSPSGKIMRRLLKDKIVERKAANSTTNSTFPK
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University