Enzyme
The enzyme participates in the flavonoid biosynthesis pathway found in plants. It catalyses the double reduction of anthocyanidins, producing (2R,3R)-flavan-3-ol monomers required for the formation of proanthocyanidins. While the enzyme from the legume Medicago truncatula (MtANR) can use both NADPH and NADH as reductant, that from the crucifer Arabidopsis thaliana (AtANR) uses only NADPH. Also, while the substrate preference of MtANR is cyanidin>pelargonidin>delphinidin, the reverse preference is found with AtANR. cf. EC 1.3.1.112, anthocyanidin reductase [(2S)-flavan-3-ol-forming].
ANR
Enzyme
Anthocyanidin reductase
Enzyme name
EC:1.3.1.77
Entry
Oxidoreductases;Acting on the CH-CH group of donors;With NAD+ or NADP+ as acceptor
Class
(2R,3R)-flavan-3-ol:NAD(P)+ 3,4-oxidoreductase
Sysname
a (2R,3R)-flavan-3-ol + 2 NAD(P)+ = an anthocyanidin with a 3-hydroxy group + 2 NAD(P)H + H+ [RN:R07351 R07352]
Reaction
anthocyanidin with a 3-hydroxy group [CPD:C21381];NADH [CPD:C00004];NADPH [CPD:C00005];H+ [CPD:C00080]
Product
Species information
Cenchrus americanus
Species name
Bulrush millet (Cenchrus americanus) is a species of monocot in the family Poaceae (grass family).
Species info
Gene sequence info
Cenchrus_americanus.ANR.fa
Download
>Pgl_GLEAN_10016955
MAEEDPEKGMIDAAVQGTLNILRSCVKAGTVKRVILTSSTAAIYSRPKLMQGSGHIVDESSWSDVEYLRANKPPMWAYGVSKVLLEKEASRFAAEHGMSLVTVCPALTIGAAPAPVVQTSVPCSLSLLSGDEAAFAVLRAIESEAGTLELVHVDDLCRAELFVAEEEEAASGELLEKPRVHLSSEKLVRDGFEFKYKTLDQLYDDVVEYGKGTRDSAQLSHMHACALLCT
>Pgl_GLEAN_10017844
MASGEAKGVAVMVTGASGFIGSTLVRRLLDRGYNVHAGVLNPDDRAETDHLLALAAGAGEGRLRIFRCDLFDGAALLDAARGCSGVFHLASPCILDAVSDPQVALPRPRCPLLSTPHPRLISSVWFWPQKQLIVPAVEGTLNVLRAAKEAGGVRRVVVTSSISAIVPSPGWPAGEVRDERCWTDVDYCEENGIELTVTVNPGGVLGPMIPPTINATMSVLLRLLQGCAEVHKDMWMGVVHVEDVALAHILAFENPSASGRHICTESISRWSDFAAKVAELYPNYKVPKFPKDTHPELVAAEVGSNKLIAMGMQFSPMENIIRDAVECLKSRGYIS
>Pgl_GLEAN_10003893
MAKNSHLKDLQVLGPLTVFRADLLEEGSFDDAVAGCDYVFLVAAPVNLASEDPEKELIEPAIRGTLNVMRSCAKAGTVKRVILTSSVGGVYIRPDLQGDGHVLDEESWSDVEYLRAEKPPLWWAYCVSKVLLEKEACRTPYIKFNARY
>Pgl_GLEAN_10003891
MSAGDKMKTACVTGGSGYIASALIKMLLEKGYAVKTTVRNPDDVAKNSHLKDLQRLGPLTVLRADLDVEGSFDDAVAGCDYAFLVAAPVSLAAGEDPEKELVETAVRGTLNVMRSCVKAGTVRRVILTSSVSAVFVRPDLHGDGDGHVLDEDSWSDVEYLRAEKPPMWGYCVSKVLVEEAASRFAEENGVSLATVCPVITVGAAPSLNVNTSVPNCLSLLSGDEVWLGVLKVIERTSGSVPLGHIDDLCRAELFVAEEPAAAGRYICCGLNTTSAELARFLADKYPQYDVERNLKLLTGDDQLLEKPRACLSSAKLVREGFEYKHNTLDELYDNVVEYGKALGILPN
>Pgl_GLEAN_10002553
MEKNTHLKRLQDLGPLEVLRADLEDEGSVDEALAGCYYAFFVAAPVNLASKNLRCTPYHYLKRLAGKNLTVEIKKNTTVEINCIPLNLHMWYRCAAQEELIGPAVQGTLNMMRSCARAGTVERVVLTSSAAAVGYSVSKVLLEKAACRFAQEHGISLVTVCPTVTVGAAPASKVHTSVLASLSLLTGDEAALGVLKGAETLFGSVPMVDVDDLCRAEILVAENEAASGSSGELLQKPRACLSSEKLVKEGFQFKYKTLDDMYDDVVEYGKALGFLSS
>Pgl_GLEAN_10002552
MAAPAGEERKKTACVTGGNGYIASLLIKMLLEKGYAVKTTVRHPENKEDNSHLEDMRKLGTLEVLRADLGEEGSYDEAVAGAFLLAAPVNYKSTNPEKELIELGVQGTLNVLRSCVKAGTVKRVILTSSTAAVSSKPLEGDGHVLDEESFSDVEYLTAKRTGLWAYPVSKVLIEQAASKFAAEHGVSLVTLCPSVTVGEAPDRQVYTTVPAILSLLSGDDKELGVLKGIERASGSVPLVHVHDVCRAEIFVAEAEAAAGRYICNALDTTIVDTARFLADKYPQYNVKRDLSGDLLKKPIALLPSTKLEKEGFEFEFKTLEHIYDDMVEYGKALGILRN
>Pgl_GLEAN_10002551
MLVAGGEKMRTACVTGGNGYIAAALVKMLLQRGYAVKATVRNPDDVQKNSHLKELQALGPLEILRADLDEEGSFDEAVAGCDYAFLVAAPVNLTSENPEKDQIEPSVRGTLNVMRSCAKAGTVRRVVLTSAASSVCIRPLEGGGGGGHVLDEESWSDLEWVTAEKPPSWGYVVSKVVSEEEAMRFAREHGMRLVIACPVLTVGASPVPKVHTSVPASLSLLSGDEAALAMLKGIERSFGGVPIVHLDDLCRAEVFLAETETAASGRYICSSLTTTVVGMARFLAEKYPQYSVSGVGNDSSGELGLEEEEPPRVRLSSAKLVEEGFQFGYKTLDEIYRDVVEYGKALGILPY
>Pgl_GLEAN_10002556
MSAAGEKKKTACVTGGNGYIASALIKMLLEKGYAVKTTVRNPDDMAKNSHLKDLQALGHLEVLRADMDEEGSFDEAVAGCDYAFLVAAPVNLASEGSEKELIEAAVRGTLNVMRSCAKAGTVRRVILTSSAGSVVIRPDLRGDGHVLDEESWSDVEYLTATKSGFWAYPVSKVLLEKEACRFAQEHGISLVTICPVITVGEAPAPAARTSVPACLSLLSGDEAAFRVLTAMEASGVVALVHVDDLCRAELFVAEEETAAGRYLCSSVDTTAREIARFLSENYPHYTVKTNLLSGDLLEKPRVRLSSAKLVGEGFEYKYRTIDGMYDDMIDYGKALGILPNL
>Pgl_GLEAN_10002555
MSAGDRKKTACVTGGSGYIASALVKMLLEKGYAVKTTVRNPDDMAKNSHLKNLQALGPLEVLRADLDEEGGFDEAVAGCDFVFLVAAPVNLRSEDPEKEVIEPAVRGTLNVMRSCVKAGTVKRVVLTSSAASIIRRPELQGDGHVLDEESWSNVEHLRAHKTGSWGYPVSKVLLEKAACSFAEEHGISLVTVCPVVTVGAAPAPTTRTSVPNCLSLLSGDEAEFAVLRGIEKMSGTVALVHVDDLCRAEVFVAEKPAAAGRYLCCSLNTTVLELARFLAGKYPQYDVKTNLLSGDLLEKPRVSVSSAKLVREGFEYEYKTLDGMYDDMVEYGKALGILPSC
>Pgl_GLEAN_10032218
MAKNSHLKDLQALGHLEKELMSMRQGRDGEARDPDLQGDGHVLYEESWSDVEYLTATKSGGAHHSGGHMMAAQEILELFCELVAVRLPIIEAQKFVPLPALHFTTPNYRWCGFGQLIYGSWGHCNLVVA
>Pgl_GLEAN_10015260
MAEEQSSDGVRVCVTGGAGFIGSWLVKKLLEKGYNVHATLRDTGDKEKAGLLRRLVPGAAERLRLFEADLFDAATFAPAIAGCQFVFLVATPYGLEAASSKYKSTAEAAVDAVRAILRLCEESKTVRRVIHTASISTTSPLKQPDASAGAYKDFISESCWTPLNVDYPLRSAHFDKYILSKLQSEQELLRYNAGERPAFEVVTLPLGLVAGDTVLGRVPETLVHAVSPVSRDEFGFAFLRLLQRLLGSLPLVHVDDVCDALVFCMERRPSIAGRFLCAAAYPTIHDVVGHFASKFPHLDILKETEEVAKVQPGEDKLGELGFRYKYDMEEILDGSVACAARLGCLDATKLSV
>Pgl_GLEAN_10015262
MEERRRSGNGVRVCVTGGAGFIGSWLVKKLLERGYTVHATLRNIGDEEKAGLLRRLLPGAAESGRLALFEADVYDAATFAPAIAGCEFVFLVATPLRHDATSTKVRSAYVPRAPNGIARYVFTQRRPHGRSCFVLDRSAHATQYKSTAEAAQDAARVILRQCADAGTVRRVIHTGSMAACSPLREDPAGFKDAVDESCWTPLDVDYPLRSAQYDEYILSKLVSEKELLAYNAGESPAFEVVTVPCSVVAGDTLQGGTTLSLEGVTSPVTRDESQLAGLRMLQQLLGSVPLAHVDDVCDALVFCMERPSMAGRFICAAAYPTFADIVGHFAAKYPHLDVLKETEDLPSVQAHSDKLGELGFRYKYGMEEILDGSIECAVRFGMLDASKLIAQG
>Pgl_GLEAN_10012037
MGSIGGGSPEDQQGTGTGGDGPPAVCVTGSTGYVGSWLVRTLLRRGYRVHATARDTGKALRVLAGVGGGDRLRVFRADMGEDGSFDAAVAGCVALFHVAASMDLHVTPGHDNNVDECVRSNVLGPATRGTINVLQSCVRAGTVRRVVFTSSVSTLTAADADGRRKAVVDESCLRDLADVWRTKPVGWIYILSKRLTEEAAFKFARENGVHLVSVILPTVAGPFLTPSVPTSVQLLLSPITGSDPKLYSLLASVHSRFGCVPLAHVQDACDAHVFLMESPRAEAGRLSRDFDASSAAAVSTKRLTDLGFRFEHGVADIVEDSVAQCLDYGFLEHPESDT
>Pgl_GLEAN_10030563
MPEYCVTGGTGFIAAHLVRALLAAGHTVRATVRDPEDEGKVGFLWELDGAAERLTLVRADLMVEGSFDEAVSGVDGVFHTASPVVVRPRRVVFTSSCSSVRYCHAATLNESHWSDADYCKSYNLWYAYAKTVAEKEAWRLAKEHGIDLVVVNPSFVIGPVLGPRPTSTILIVLAMLKGELGKYPNTTIGFVHVDDVVLCHVLAMEDARASGRLICSCDVAHWSEILGSLRERYPQYPIPTECSAQKGDDRPHRMDTTKIRALGFPPFLSVHQMFDDCIKSFQDKGLLPY
>Pgl_GLEAN_10032690
MAGSSTVCVTGAGGFIASWLVKLLLSRGYTVHATVRDLVTKTAHLKRLENAAANLELFKADLLDYDAMAAAIVGCQGVFHVATPVTSDKLTDPELQMLAPAITGTTNVLTAASAANVQRVVVVSSIVAVEINPKSWYPVAKIISEEAALEYGHRTGLDVVTVNPGLVFGPLLQPTVNASSQFLIYLLKGGPDKARNKLWHIVDVRDLAEALLLVYDVHQASGRHICAPHVISVRDLLDLLKRKYPGYPYITKESICDKDHPASMTSEKLEKLG
>Pgl_GLEAN_10019438
MAGEGEKKVRGTVVCVTGGAGYIGSWLVRKLLGRGCVVHATLRSLEDEKKAGLLRSLPSAAERLRLFQADIYDADTFEPAIAGCEFVFLVATPLAHDPTSTKGFPQYKNVTEATVDAVRTILRLCERSGTVRRVIHTASVTAASPLREDGSGGYKDSINESCWTPLNLSYGFSNAHLDGYVWSKSLSEKELLGHNDGGGEARPAFEVVTLACALTGGDTIQPYLWSSIPVIVAPLTGQAAYHNSLLFMQALMGSVPLAHVEDVCEAHVFCMDQPAMAGRFLCAAGYPSMRDIVDRFAAKYPEIEIKLPQVTGEGVRVRADTSKLEDLGFRYRYGVEETLDASVECAKRLGEL
MAEEDPEKGMIDAAVQGTLNILRSCVKAGTVKRVILTSSTAAIYSRPKLMQGSGHIVDESSWSDVEYLRANKPPMWAYGVSKVLLEKEASRFAAEHGMSLVTVCPALTIGAAPAPVVQTSVPCSLSLLSGDEAAFAVLRAIESEAGTLELVHVDDLCRAELFVAEEEEAASGELLEKPRVHLSSEKLVRDGFEFKYKTLDQLYDDVVEYGKGTRDSAQLSHMHACALLCT
>Pgl_GLEAN_10017844
MASGEAKGVAVMVTGASGFIGSTLVRRLLDRGYNVHAGVLNPDDRAETDHLLALAAGAGEGRLRIFRCDLFDGAALLDAARGCSGVFHLASPCILDAVSDPQVALPRPRCPLLSTPHPRLISSVWFWPQKQLIVPAVEGTLNVLRAAKEAGGVRRVVVTSSISAIVPSPGWPAGEVRDERCWTDVDYCEENGIELTVTVNPGGVLGPMIPPTINATMSVLLRLLQGCAEVHKDMWMGVVHVEDVALAHILAFENPSASGRHICTESISRWSDFAAKVAELYPNYKVPKFPKDTHPELVAAEVGSNKLIAMGMQFSPMENIIRDAVECLKSRGYIS
>Pgl_GLEAN_10003893
MAKNSHLKDLQVLGPLTVFRADLLEEGSFDDAVAGCDYVFLVAAPVNLASEDPEKELIEPAIRGTLNVMRSCAKAGTVKRVILTSSVGGVYIRPDLQGDGHVLDEESWSDVEYLRAEKPPLWWAYCVSKVLLEKEACRTPYIKFNARY
>Pgl_GLEAN_10003891
MSAGDKMKTACVTGGSGYIASALIKMLLEKGYAVKTTVRNPDDVAKNSHLKDLQRLGPLTVLRADLDVEGSFDDAVAGCDYAFLVAAPVSLAAGEDPEKELVETAVRGTLNVMRSCVKAGTVRRVILTSSVSAVFVRPDLHGDGDGHVLDEDSWSDVEYLRAEKPPMWGYCVSKVLVEEAASRFAEENGVSLATVCPVITVGAAPSLNVNTSVPNCLSLLSGDEVWLGVLKVIERTSGSVPLGHIDDLCRAELFVAEEPAAAGRYICCGLNTTSAELARFLADKYPQYDVERNLKLLTGDDQLLEKPRACLSSAKLVREGFEYKHNTLDELYDNVVEYGKALGILPN
>Pgl_GLEAN_10002553
MEKNTHLKRLQDLGPLEVLRADLEDEGSVDEALAGCYYAFFVAAPVNLASKNLRCTPYHYLKRLAGKNLTVEIKKNTTVEINCIPLNLHMWYRCAAQEELIGPAVQGTLNMMRSCARAGTVERVVLTSSAAAVGYSVSKVLLEKAACRFAQEHGISLVTVCPTVTVGAAPASKVHTSVLASLSLLTGDEAALGVLKGAETLFGSVPMVDVDDLCRAEILVAENEAASGSSGELLQKPRACLSSEKLVKEGFQFKYKTLDDMYDDVVEYGKALGFLSS
>Pgl_GLEAN_10002552
MAAPAGEERKKTACVTGGNGYIASLLIKMLLEKGYAVKTTVRHPENKEDNSHLEDMRKLGTLEVLRADLGEEGSYDEAVAGAFLLAAPVNYKSTNPEKELIELGVQGTLNVLRSCVKAGTVKRVILTSSTAAVSSKPLEGDGHVLDEESFSDVEYLTAKRTGLWAYPVSKVLIEQAASKFAAEHGVSLVTLCPSVTVGEAPDRQVYTTVPAILSLLSGDDKELGVLKGIERASGSVPLVHVHDVCRAEIFVAEAEAAAGRYICNALDTTIVDTARFLADKYPQYNVKRDLSGDLLKKPIALLPSTKLEKEGFEFEFKTLEHIYDDMVEYGKALGILRN
>Pgl_GLEAN_10002551
MLVAGGEKMRTACVTGGNGYIAAALVKMLLQRGYAVKATVRNPDDVQKNSHLKELQALGPLEILRADLDEEGSFDEAVAGCDYAFLVAAPVNLTSENPEKDQIEPSVRGTLNVMRSCAKAGTVRRVVLTSAASSVCIRPLEGGGGGGHVLDEESWSDLEWVTAEKPPSWGYVVSKVVSEEEAMRFAREHGMRLVIACPVLTVGASPVPKVHTSVPASLSLLSGDEAALAMLKGIERSFGGVPIVHLDDLCRAEVFLAETETAASGRYICSSLTTTVVGMARFLAEKYPQYSVSGVGNDSSGELGLEEEEPPRVRLSSAKLVEEGFQFGYKTLDEIYRDVVEYGKALGILPY
>Pgl_GLEAN_10002556
MSAAGEKKKTACVTGGNGYIASALIKMLLEKGYAVKTTVRNPDDMAKNSHLKDLQALGHLEVLRADMDEEGSFDEAVAGCDYAFLVAAPVNLASEGSEKELIEAAVRGTLNVMRSCAKAGTVRRVILTSSAGSVVIRPDLRGDGHVLDEESWSDVEYLTATKSGFWAYPVSKVLLEKEACRFAQEHGISLVTICPVITVGEAPAPAARTSVPACLSLLSGDEAAFRVLTAMEASGVVALVHVDDLCRAELFVAEEETAAGRYLCSSVDTTAREIARFLSENYPHYTVKTNLLSGDLLEKPRVRLSSAKLVGEGFEYKYRTIDGMYDDMIDYGKALGILPNL
>Pgl_GLEAN_10002555
MSAGDRKKTACVTGGSGYIASALVKMLLEKGYAVKTTVRNPDDMAKNSHLKNLQALGPLEVLRADLDEEGGFDEAVAGCDFVFLVAAPVNLRSEDPEKEVIEPAVRGTLNVMRSCVKAGTVKRVVLTSSAASIIRRPELQGDGHVLDEESWSNVEHLRAHKTGSWGYPVSKVLLEKAACSFAEEHGISLVTVCPVVTVGAAPAPTTRTSVPNCLSLLSGDEAEFAVLRGIEKMSGTVALVHVDDLCRAEVFVAEKPAAAGRYLCCSLNTTVLELARFLAGKYPQYDVKTNLLSGDLLEKPRVSVSSAKLVREGFEYEYKTLDGMYDDMVEYGKALGILPSC
>Pgl_GLEAN_10032218
MAKNSHLKDLQALGHLEKELMSMRQGRDGEARDPDLQGDGHVLYEESWSDVEYLTATKSGGAHHSGGHMMAAQEILELFCELVAVRLPIIEAQKFVPLPALHFTTPNYRWCGFGQLIYGSWGHCNLVVA
>Pgl_GLEAN_10015260
MAEEQSSDGVRVCVTGGAGFIGSWLVKKLLEKGYNVHATLRDTGDKEKAGLLRRLVPGAAERLRLFEADLFDAATFAPAIAGCQFVFLVATPYGLEAASSKYKSTAEAAVDAVRAILRLCEESKTVRRVIHTASISTTSPLKQPDASAGAYKDFISESCWTPLNVDYPLRSAHFDKYILSKLQSEQELLRYNAGERPAFEVVTLPLGLVAGDTVLGRVPETLVHAVSPVSRDEFGFAFLRLLQRLLGSLPLVHVDDVCDALVFCMERRPSIAGRFLCAAAYPTIHDVVGHFASKFPHLDILKETEEVAKVQPGEDKLGELGFRYKYDMEEILDGSVACAARLGCLDATKLSV
>Pgl_GLEAN_10015262
MEERRRSGNGVRVCVTGGAGFIGSWLVKKLLERGYTVHATLRNIGDEEKAGLLRRLLPGAAESGRLALFEADVYDAATFAPAIAGCEFVFLVATPLRHDATSTKVRSAYVPRAPNGIARYVFTQRRPHGRSCFVLDRSAHATQYKSTAEAAQDAARVILRQCADAGTVRRVIHTGSMAACSPLREDPAGFKDAVDESCWTPLDVDYPLRSAQYDEYILSKLVSEKELLAYNAGESPAFEVVTVPCSVVAGDTLQGGTTLSLEGVTSPVTRDESQLAGLRMLQQLLGSVPLAHVDDVCDALVFCMERPSMAGRFICAAAYPTFADIVGHFAAKYPHLDVLKETEDLPSVQAHSDKLGELGFRYKYGMEEILDGSIECAVRFGMLDASKLIAQG
>Pgl_GLEAN_10012037
MGSIGGGSPEDQQGTGTGGDGPPAVCVTGSTGYVGSWLVRTLLRRGYRVHATARDTGKALRVLAGVGGGDRLRVFRADMGEDGSFDAAVAGCVALFHVAASMDLHVTPGHDNNVDECVRSNVLGPATRGTINVLQSCVRAGTVRRVVFTSSVSTLTAADADGRRKAVVDESCLRDLADVWRTKPVGWIYILSKRLTEEAAFKFARENGVHLVSVILPTVAGPFLTPSVPTSVQLLLSPITGSDPKLYSLLASVHSRFGCVPLAHVQDACDAHVFLMESPRAEAGRLSRDFDASSAAAVSTKRLTDLGFRFEHGVADIVEDSVAQCLDYGFLEHPESDT
>Pgl_GLEAN_10030563
MPEYCVTGGTGFIAAHLVRALLAAGHTVRATVRDPEDEGKVGFLWELDGAAERLTLVRADLMVEGSFDEAVSGVDGVFHTASPVVVRPRRVVFTSSCSSVRYCHAATLNESHWSDADYCKSYNLWYAYAKTVAEKEAWRLAKEHGIDLVVVNPSFVIGPVLGPRPTSTILIVLAMLKGELGKYPNTTIGFVHVDDVVLCHVLAMEDARASGRLICSCDVAHWSEILGSLRERYPQYPIPTECSAQKGDDRPHRMDTTKIRALGFPPFLSVHQMFDDCIKSFQDKGLLPY
>Pgl_GLEAN_10032690
MAGSSTVCVTGAGGFIASWLVKLLLSRGYTVHATVRDLVTKTAHLKRLENAAANLELFKADLLDYDAMAAAIVGCQGVFHVATPVTSDKLTDPELQMLAPAITGTTNVLTAASAANVQRVVVVSSIVAVEINPKSWYPVAKIISEEAALEYGHRTGLDVVTVNPGLVFGPLLQPTVNASSQFLIYLLKGGPDKARNKLWHIVDVRDLAEALLLVYDVHQASGRHICAPHVISVRDLLDLLKRKYPGYPYITKESICDKDHPASMTSEKLEKLG
>Pgl_GLEAN_10019438
MAGEGEKKVRGTVVCVTGGAGYIGSWLVRKLLGRGCVVHATLRSLEDEKKAGLLRSLPSAAERLRLFQADIYDADTFEPAIAGCEFVFLVATPLAHDPTSTKGFPQYKNVTEATVDAVRTILRLCERSGTVRRVIHTASVTAASPLREDGSGGYKDSINESCWTPLNLSYGFSNAHLDGYVWSKSLSEKELLGHNDGGGEARPAFEVVTLACALTGGDTIQPYLWSSIPVIVAPLTGQAAYHNSLLFMQALMGSVPLAHVEDVCEAHVFCMDQPAMAGRFLCAAGYPSMRDIVDRFAAKYPEIEIKLPQVTGEGVRVRADTSKLEDLGFRYRYGVEETLDASVECAKRLGEL
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University