Enzyme
Isolated from the plant Gentiana triflora. Transfers the hydroxycinnamoyl group only to the C-5 glucoside of anthocyanin. Caffeoyl-CoA, but not malonyl-CoA, can substitute as an acyl donor.
5AT
Enzyme
Anthocyanin 5-aromatic acyltransferase
Enzyme name
EC:2.3.1.153
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
4-hydroxycinnamoyl-CoA:anthocyanidin 3,5-di-O-beta-D-glucoside 5-O-glucoside-6'''-O-4-hydroxycinnamoyltransferase
Sysname
4-hydroxycinnamoyl-CoA + an anthocyanidin 3,5-di-O-beta-D-glucoside = CoA + anthocyanidin 3-O-beta-D-glucoside 5-O-beta-D-(6-O-4-hydroxycinnamoylglucoside) [RN:R05163]
Reaction
CoA [CPD:C00010];anthocyanidin 3-O-beta-D-glucoside 5-O-beta-D-(6-O-4-hydroxycinnamoylglucoside) [CPD:C06363]
Product
Species information
Catharanthus roseu
Species name
Species info
Gene sequence info
Catharanthus_roseu.5AT.fa
Download
>CRO_T013752
MASKMVTETISKLVIKPSSPTPESLRHYNLSSVDQIMPSVYGSLAFFYPDPCKEISTICEELQNSLAKTLSHYYPFAGKLIENDYIDCNDQGVEFVQVRINFPMSDILRTTKSEVADLVFPREVAAGSEDYLVVVQLSQFDCGGIGVGLCVSNKVADASTIVNFMVDWASSARISSHMPTPVLLSDSVFPHGNGISPPPFEPSPNCVARKFLFSAQEIEKLKSMVVESGIDEPTSEEVVAAVLYHSAINCGSSKAAAVLIGRYLLRPLFELSENSVGNMTTFYFCINSQDEKSEFPALVGKIKKAKLKLATLSKEEINYDSQFKDLEKCLSNINNSSFEVYLLSTFCGSPIYEVDFGWGKPIRVTRLISKLKDLLSLMDSPEGGIETLVILDEEKMAKFEKNQLLLSYASLI
>CRO_T025623
MAATLVSKRIINCSFPRIHTKTSLISKRIIKPISPTPNSLSCYNLSSSDQTLPNIYVPFAFFYPSVTNQFERSQISQQIENGLSKTLASYYPFAGRLVENHHISCNDAGINFQEIQINSSISEIFKKSQEDIVFPRGLQWSSIQNPIDHSLVFVQLNYFDCGGVAISFCMSHKIADGSTFGTFVNDLATMSCQENYVPSPQFISSTIFPRVENPISFPPNLPTNGISKRVIFHAEKIAALKTLANNLGIEKPTRVEVVTALLYQRALASSDSSLVRQSILIQPINLRPLIGLRPDSVGNIWAMNILVTKNNQMSFQEMVNELRKSKVKIQNIYKQKLNSSSPMQDMLRDFFNLVGRGGFDVYHCSSNCRFPYYEVDFGWGKPIRVSIGQYPGKDTFFLIDTPENGIEALVNLDEQTMLRFEKDKELLSFVSLRSTE
>CRO_T005108
MVALKVTESCRVAPPPGTVAAALPLTFWNARNCDQFYSLIPKIPPPFIEFGIEKTLLSALQLDGNLCIFMGLLAKVIGSNWGKSEQSRNQYFICPVNFRTRLHPSPPMTYFENCVGHSLAKLMYGEIIESDCLINAAVSIGEAIHTSINDLETVWNGTEDAKVAEVIQGRVFIVNGSPLLFDTHGVDFGWGKMNTFEPMITDIDGSLFIQGSRKFQGAVEIVSSLEKKRMDAFATIFNTHLSYDFGKKAT
>CRO_T012699
MVSQVEIVSKEIIKPSSPTPSLINLKLSFLDKLEGTNYGSILLFYENHTSPKLKRPQISHKLKQSLSETLTKFYPYAGRINGNNDSIDCNDSGALFVEAQVHSDLLQKIQSATKTDINQYLPINTSQSHQNYETNNFFPLAVQISFFRCGGVGIGVCLSHGVADMYTLATFVNSWAANCSGRTENFQPDFQIGNELFPLIEIPADQVPDPAAVHDFVAGEEKIVTKRLIFDVEILGEMKKQASSRSSSDNPTTVETISAFIWKHMIDAIRAKTATKKAFGAFHSVDIRRRISPPIPNAMGNFIVATLARCDSKDSGDFCDLVTPLREAIRKDYKEYIKNEQKILEYLGLLSKSEPERTCCLFTSICKFPLYEMEFGWGKPFAFFPMDQKIKNGVILMDTKSGDGIEAWISMAEDEMGMLPTQFLELENDAF
>CRO_T020282
MMFLTYGSLAFFYVNPPKRSTFYEQLRNSLAKILVHYYPLAGRVVKNEYINCNDQGVELVEIRINCSMYDLMNTRETNVADLIFPRRVVATSEDCLLALQLSHFNCGGVAISICISHKIADGSTILAFMTDWAASTRLSSYVPSPVMLSDSLFPSRDNIFPAPYDVPLENSLTKRLVFSPIELEKLKYMAVEFGIQNPSRTEIVTALLFQCAMVATKVTNGGLSKPSILISSVNLRPLFGLPLNAVGNLLSFYFCVIEDVEMEFPALVGEIRQAKLRLKNLPKEKLSYESRMQQLGECLTELNDVSSFDVYLSTSLCGFPVKDVDFGWGKPISGSMLQSQTKDTMILLGSPGDGVEALVIFDEQKMAAFDKNENLLPFTSFNDSVKWKSKL
>CRO_T013624
MHCYTATSFSSSSSSSSSSSSSSSSSSSPGNNNFTTMVSKCTVFPSEKSTLGDLKLSVSDLPMLSCHYIQKGCLFTLPPFPISELISSLKRALSQTLTHFPPLAGRLLTDADGYIYITCNDAGVDFIHADASRLHINDILVGSGYVPDQFKEFFTMDRIVSYEGHFRPILAVQVTELADGVFIGCTVNHAVTDGTSFWNFFNSFAEISRGAKMISRTPDLSRNSVLISSAVLKVPAGGPTVTFNIDAPLSERIFSFTRESILKMKAKANSTPSWINGGLDIAELMGKQRNDPLTAMDGKLTAEISSFQALCALLWRAVTRARKLPNSKVTTFRMAVNCRHRLEPKLEPLYFGNAIQSIPTYASAGDVLDRDLRWCAEQLNKNVLAHSDATVRKYVEDWERDPRCFPLGNFDGAMLTMGSSPRFPMFDNDFGWGRPVAVRSGKANKFDGKISAFPGREGNGSVDLEVLLAPETMVGLESDPEFMQYVSTN
>CRO_T014328
MPSSSVLIISKCTVYPECKSTINSLKLSVSDLPMLSCQYIQKGVLLSQPPFDDSFDLLTLLKLCLSRTLSHFPALAGRLNTDSQGHVHILCNDAGVDFVHAKAIHLSTAALLPPNLDIPPCFRKFFQYDNTLSYEGHYKPLVAVQVTELKDGVFIGCTINHAVVDGTSFWNFFNTFAEVCKGAKKISKSPNFSRETPFDSPAVLRFPAGGPSVTFSIDEPLREKIFHFSREAILKMKFRANNPGRKFSDSEIEPENFGKTTYNGENVRSNNKITPVTENELAKATAAISSFQSLCAQLWRSVTRARNLDASKTTTFRMAVNCRHRLEPRLEPLYFGNAIQSIPTVASVGELLSKDLSWCAGLLHQNVVAHDNDTVRRGIKDWESNPRLFPLGNFDGAMITMGSSPRFPMYDNDFGWGRPLAVRSGRANKFDGKISAFPGREGNGSVDLEVVLESETMAGLENDMEIMQYVS
>CRO_T002364
MPSVLVFRTKKDATLCVGDGVMERWRLPSGQVGPNQWSTSWIVIENPNMEELIEYLLIDQKSQGGGRNEKGKNVLAVQINFFNCGGIGIGVQMSHRIGDGTSLVTFMNTWAATCRGVKEISKPIFDISKLFPPQNLHSFGLKPHNWISKEKIVTKRFLFKKQNIEKLKEAIVSDLESKVTDPSRVEAVTSFIWRKMIKIHKTKVGKESTFAISHAVNMRPRMTQIRNINRDHNICEYMIKTLKSMSDTISKEEIEYCNFSSWCRFPVYQVDCGWGKPVWVSTTTFPLKNIAILMSNRNGDGIEAWINMAEDDALIFSRNQMDFSCIAPNDTKII
>CRO_T005215
MASKMVEIVSKMFIKPSSPTPQSLRRYNLSSIDQTIDSEVTSLAFFYTYNPSHESSKIGDLLKNSLSKTLVSYYQFAGRLIENDYIDCNDEGVEFVEVRIHGRMNDILKRGKSFATDLVLPTRIIALHEDSLLIVQLSHFDCGGIAIGFGASHKVSDGVSNVMFMKDWASSTSLSTFHKPTPLLTADSIFPPEDNKLLSNKSIVSFQQCLGKRFVFSTEAIEKLKSKAIEYGIQKPSRVEVVTAFLCQCAANCDLPRKKPYAIISAVNLRPYLALPQNSIGNIFSFYFCINDEGMDNQFSALISKLRNGKQKLLENIISKEKLTYESQMQELTKCLDQLNISSLDTYFCSSWCRFPVYDIDFGWGKPILVSPFQPHVKDLILLMDSPEGDGIEALITMEEKKMAAFEKNEELRSFAYLDSPEPEALIIPEEDKSFE
>CRO_T005210
METKMIERVSRKVIKPSSPTPQSLRRYILSSFDQMMSQIYVSCAFYYTNPGHHNISSIAKKLQNSLSKALTQYYHFAGRLVENNYIDCSDQGVEFMEARIHCPINDVLNSKSTYAVDLIFPRGASPNEDCLVAFQVSYFDCGGVAIALCITHKIADACTLYTFMNNLATSTRLSSQVPTPLLLSDSIFPCGNDIVPRPLNPTDNCVSKTFTFPASKIEKLKLKAIELGISKPTRTEVISAFLFQCANNCGKFRPSAMLTAINLRPLLGLPQNAVGNMFSSYFCIIEDERMEFPAILGELRKEKLKLQNLPKEKLFFASRMQELGECLIKINQGCSSEPEVYFCSSAVGFSTQNTDFGSGKPEWMFMFLPEQKNSIFLFDSPGGGIEALVIFEEEKMSAFQNNLLLLPFTSAKHKSKL
>CRO_T005211
MASKLVEKVFIKPSSPTPESLRHYNLSSYDQLMPEYYISCMLFYPNPHHEISTICLQLKNSLSKTLVPYYPLAGRLVKNDYIDCNDQGIEFIQVRIHCQLDSFLKKTRFYAADQNLLCGSAEDSLVVVQLSHFDCGGVAIAVSISHKVADGSAAAAFMNDWALSTRLSSHMPTPLLVSDSLFPPGNNVISRPFVPCHNCVMRRFLFPVEDIEKLKTKAIESGILGPTKVEVVIALLYQCATVAKRSSRNGFSRTSVLSQTVNLRPSLKLPQNAIGNMFSLHFCFVEDDKMEIPALIGEIRKAKLKLRKLPYESQMKELGESLEKLDPNTVDIYVFSSLCGFPIYDIDFGWGKPTRVQAFQNEINNQIFLMDSPQDGIEAFVILEEEMISAFENNELLLPFTSLDSIKLKSKI
>CRO_T015230
MSKSPQLPDCVYSEEPILIKPCNPTPNHSIYLSNLDDYDFLRFSVKYIFLFKKSVPIDSLKASLSRVLVDYYPLAGRLKISPENNEKFEVDCNGEGAVFAEASMDLTADEFTQIFDEPNKTWWKLLCKIHTPTFLDIPPLVIQVTNLKCGAIILCIGVHHFLSDGTGTSQFLHAWAHLTRNQGADLPMTPSHLRHVFKSRNPPQVTFSHPTFTESEPDNSISQKALNLPQYLRSRAPLVTVSLTFTADHILQLKKQCEPLLKCTGFEALASHTWRCWVKALDLPPSATVKLLFSASVRKAFNPELLPQGYYGNGFVLACAEATVKDVSDANLHGSVKMVQNAKSSLTEDYVRSMIDYLEDKTVKTDLCSSFVITQWSKLGLEELDFGEGKPVRMGPLVSSIYCLFLPVIGDRNAVRVLLSMPESTVSNFKNYMTEHGGQDRCTLE
MASKMVTETISKLVIKPSSPTPESLRHYNLSSVDQIMPSVYGSLAFFYPDPCKEISTICEELQNSLAKTLSHYYPFAGKLIENDYIDCNDQGVEFVQVRINFPMSDILRTTKSEVADLVFPREVAAGSEDYLVVVQLSQFDCGGIGVGLCVSNKVADASTIVNFMVDWASSARISSHMPTPVLLSDSVFPHGNGISPPPFEPSPNCVARKFLFSAQEIEKLKSMVVESGIDEPTSEEVVAAVLYHSAINCGSSKAAAVLIGRYLLRPLFELSENSVGNMTTFYFCINSQDEKSEFPALVGKIKKAKLKLATLSKEEINYDSQFKDLEKCLSNINNSSFEVYLLSTFCGSPIYEVDFGWGKPIRVTRLISKLKDLLSLMDSPEGGIETLVILDEEKMAKFEKNQLLLSYASLI
>CRO_T025623
MAATLVSKRIINCSFPRIHTKTSLISKRIIKPISPTPNSLSCYNLSSSDQTLPNIYVPFAFFYPSVTNQFERSQISQQIENGLSKTLASYYPFAGRLVENHHISCNDAGINFQEIQINSSISEIFKKSQEDIVFPRGLQWSSIQNPIDHSLVFVQLNYFDCGGVAISFCMSHKIADGSTFGTFVNDLATMSCQENYVPSPQFISSTIFPRVENPISFPPNLPTNGISKRVIFHAEKIAALKTLANNLGIEKPTRVEVVTALLYQRALASSDSSLVRQSILIQPINLRPLIGLRPDSVGNIWAMNILVTKNNQMSFQEMVNELRKSKVKIQNIYKQKLNSSSPMQDMLRDFFNLVGRGGFDVYHCSSNCRFPYYEVDFGWGKPIRVSIGQYPGKDTFFLIDTPENGIEALVNLDEQTMLRFEKDKELLSFVSLRSTE
>CRO_T005108
MVALKVTESCRVAPPPGTVAAALPLTFWNARNCDQFYSLIPKIPPPFIEFGIEKTLLSALQLDGNLCIFMGLLAKVIGSNWGKSEQSRNQYFICPVNFRTRLHPSPPMTYFENCVGHSLAKLMYGEIIESDCLINAAVSIGEAIHTSINDLETVWNGTEDAKVAEVIQGRVFIVNGSPLLFDTHGVDFGWGKMNTFEPMITDIDGSLFIQGSRKFQGAVEIVSSLEKKRMDAFATIFNTHLSYDFGKKAT
>CRO_T012699
MVSQVEIVSKEIIKPSSPTPSLINLKLSFLDKLEGTNYGSILLFYENHTSPKLKRPQISHKLKQSLSETLTKFYPYAGRINGNNDSIDCNDSGALFVEAQVHSDLLQKIQSATKTDINQYLPINTSQSHQNYETNNFFPLAVQISFFRCGGVGIGVCLSHGVADMYTLATFVNSWAANCSGRTENFQPDFQIGNELFPLIEIPADQVPDPAAVHDFVAGEEKIVTKRLIFDVEILGEMKKQASSRSSSDNPTTVETISAFIWKHMIDAIRAKTATKKAFGAFHSVDIRRRISPPIPNAMGNFIVATLARCDSKDSGDFCDLVTPLREAIRKDYKEYIKNEQKILEYLGLLSKSEPERTCCLFTSICKFPLYEMEFGWGKPFAFFPMDQKIKNGVILMDTKSGDGIEAWISMAEDEMGMLPTQFLELENDAF
>CRO_T020282
MMFLTYGSLAFFYVNPPKRSTFYEQLRNSLAKILVHYYPLAGRVVKNEYINCNDQGVELVEIRINCSMYDLMNTRETNVADLIFPRRVVATSEDCLLALQLSHFNCGGVAISICISHKIADGSTILAFMTDWAASTRLSSYVPSPVMLSDSLFPSRDNIFPAPYDVPLENSLTKRLVFSPIELEKLKYMAVEFGIQNPSRTEIVTALLFQCAMVATKVTNGGLSKPSILISSVNLRPLFGLPLNAVGNLLSFYFCVIEDVEMEFPALVGEIRQAKLRLKNLPKEKLSYESRMQQLGECLTELNDVSSFDVYLSTSLCGFPVKDVDFGWGKPISGSMLQSQTKDTMILLGSPGDGVEALVIFDEQKMAAFDKNENLLPFTSFNDSVKWKSKL
>CRO_T013624
MHCYTATSFSSSSSSSSSSSSSSSSSSSPGNNNFTTMVSKCTVFPSEKSTLGDLKLSVSDLPMLSCHYIQKGCLFTLPPFPISELISSLKRALSQTLTHFPPLAGRLLTDADGYIYITCNDAGVDFIHADASRLHINDILVGSGYVPDQFKEFFTMDRIVSYEGHFRPILAVQVTELADGVFIGCTVNHAVTDGTSFWNFFNSFAEISRGAKMISRTPDLSRNSVLISSAVLKVPAGGPTVTFNIDAPLSERIFSFTRESILKMKAKANSTPSWINGGLDIAELMGKQRNDPLTAMDGKLTAEISSFQALCALLWRAVTRARKLPNSKVTTFRMAVNCRHRLEPKLEPLYFGNAIQSIPTYASAGDVLDRDLRWCAEQLNKNVLAHSDATVRKYVEDWERDPRCFPLGNFDGAMLTMGSSPRFPMFDNDFGWGRPVAVRSGKANKFDGKISAFPGREGNGSVDLEVLLAPETMVGLESDPEFMQYVSTN
>CRO_T014328
MPSSSVLIISKCTVYPECKSTINSLKLSVSDLPMLSCQYIQKGVLLSQPPFDDSFDLLTLLKLCLSRTLSHFPALAGRLNTDSQGHVHILCNDAGVDFVHAKAIHLSTAALLPPNLDIPPCFRKFFQYDNTLSYEGHYKPLVAVQVTELKDGVFIGCTINHAVVDGTSFWNFFNTFAEVCKGAKKISKSPNFSRETPFDSPAVLRFPAGGPSVTFSIDEPLREKIFHFSREAILKMKFRANNPGRKFSDSEIEPENFGKTTYNGENVRSNNKITPVTENELAKATAAISSFQSLCAQLWRSVTRARNLDASKTTTFRMAVNCRHRLEPRLEPLYFGNAIQSIPTVASVGELLSKDLSWCAGLLHQNVVAHDNDTVRRGIKDWESNPRLFPLGNFDGAMITMGSSPRFPMYDNDFGWGRPLAVRSGRANKFDGKISAFPGREGNGSVDLEVVLESETMAGLENDMEIMQYVS
>CRO_T002364
MPSVLVFRTKKDATLCVGDGVMERWRLPSGQVGPNQWSTSWIVIENPNMEELIEYLLIDQKSQGGGRNEKGKNVLAVQINFFNCGGIGIGVQMSHRIGDGTSLVTFMNTWAATCRGVKEISKPIFDISKLFPPQNLHSFGLKPHNWISKEKIVTKRFLFKKQNIEKLKEAIVSDLESKVTDPSRVEAVTSFIWRKMIKIHKTKVGKESTFAISHAVNMRPRMTQIRNINRDHNICEYMIKTLKSMSDTISKEEIEYCNFSSWCRFPVYQVDCGWGKPVWVSTTTFPLKNIAILMSNRNGDGIEAWINMAEDDALIFSRNQMDFSCIAPNDTKII
>CRO_T005215
MASKMVEIVSKMFIKPSSPTPQSLRRYNLSSIDQTIDSEVTSLAFFYTYNPSHESSKIGDLLKNSLSKTLVSYYQFAGRLIENDYIDCNDEGVEFVEVRIHGRMNDILKRGKSFATDLVLPTRIIALHEDSLLIVQLSHFDCGGIAIGFGASHKVSDGVSNVMFMKDWASSTSLSTFHKPTPLLTADSIFPPEDNKLLSNKSIVSFQQCLGKRFVFSTEAIEKLKSKAIEYGIQKPSRVEVVTAFLCQCAANCDLPRKKPYAIISAVNLRPYLALPQNSIGNIFSFYFCINDEGMDNQFSALISKLRNGKQKLLENIISKEKLTYESQMQELTKCLDQLNISSLDTYFCSSWCRFPVYDIDFGWGKPILVSPFQPHVKDLILLMDSPEGDGIEALITMEEKKMAAFEKNEELRSFAYLDSPEPEALIIPEEDKSFE
>CRO_T005210
METKMIERVSRKVIKPSSPTPQSLRRYILSSFDQMMSQIYVSCAFYYTNPGHHNISSIAKKLQNSLSKALTQYYHFAGRLVENNYIDCSDQGVEFMEARIHCPINDVLNSKSTYAVDLIFPRGASPNEDCLVAFQVSYFDCGGVAIALCITHKIADACTLYTFMNNLATSTRLSSQVPTPLLLSDSIFPCGNDIVPRPLNPTDNCVSKTFTFPASKIEKLKLKAIELGISKPTRTEVISAFLFQCANNCGKFRPSAMLTAINLRPLLGLPQNAVGNMFSSYFCIIEDERMEFPAILGELRKEKLKLQNLPKEKLFFASRMQELGECLIKINQGCSSEPEVYFCSSAVGFSTQNTDFGSGKPEWMFMFLPEQKNSIFLFDSPGGGIEALVIFEEEKMSAFQNNLLLLPFTSAKHKSKL
>CRO_T005211
MASKLVEKVFIKPSSPTPESLRHYNLSSYDQLMPEYYISCMLFYPNPHHEISTICLQLKNSLSKTLVPYYPLAGRLVKNDYIDCNDQGIEFIQVRIHCQLDSFLKKTRFYAADQNLLCGSAEDSLVVVQLSHFDCGGVAIAVSISHKVADGSAAAAFMNDWALSTRLSSHMPTPLLVSDSLFPPGNNVISRPFVPCHNCVMRRFLFPVEDIEKLKTKAIESGILGPTKVEVVIALLYQCATVAKRSSRNGFSRTSVLSQTVNLRPSLKLPQNAIGNMFSLHFCFVEDDKMEIPALIGEIRKAKLKLRKLPYESQMKELGESLEKLDPNTVDIYVFSSLCGFPIYDIDFGWGKPTRVQAFQNEINNQIFLMDSPQDGIEAFVILEEEMISAFENNELLLPFTSLDSIKLKSKI
>CRO_T015230
MSKSPQLPDCVYSEEPILIKPCNPTPNHSIYLSNLDDYDFLRFSVKYIFLFKKSVPIDSLKASLSRVLVDYYPLAGRLKISPENNEKFEVDCNGEGAVFAEASMDLTADEFTQIFDEPNKTWWKLLCKIHTPTFLDIPPLVIQVTNLKCGAIILCIGVHHFLSDGTGTSQFLHAWAHLTRNQGADLPMTPSHLRHVFKSRNPPQVTFSHPTFTESEPDNSISQKALNLPQYLRSRAPLVTVSLTFTADHILQLKKQCEPLLKCTGFEALASHTWRCWVKALDLPPSATVKLLFSASVRKAFNPELLPQGYYGNGFVLACAEATVKDVSDANLHGSVKMVQNAKSSLTEDYVRSMIDYLEDKTVKTDLCSSFVITQWSKLGLEELDFGEGKPVRMGPLVSSIYCLFLPVIGDRNAVRVLLSMPESTVSNFKNYMTEHGGQDRCTLE
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University