Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Casuarina glauca
Species name
Swamp oak (Casuarina glauca) is a species of eudicot in the family Casuarinaceae.
Species info
Gene sequence info
Casuarina_glauca.COMT.fa
Download
>Casgl31S04856
MNLKKCSQLDDFLQRTLHNWSDEWCLKLLRNCYNTNPKGEKAIIVKAVASMMPKITSAAHIKCQMDMLLMTQIGGKEKTMNELHGMAYEAGFSSIKYMCFVCNFAVMEFLM
>Casgl31S15449
MASPLTSTSRVLDDDGKEEESFLYAMQVATSVVMPMAMQSAVELGVFEILAKAGPGAKLSPSQIVEQMPTKNPEAPVMLDRILRMLATHSLLACSVVADDCGSYQRLYSLSPMSKHFVFDEDGVSLGPFMALIQDKVFLDSWSQLKDAILEGGIPFNRFHGMHAFDYPGIDPRFNQVFNKRCSTRPLRRSLSLIGVLNINQLVDVVGNLGVTLNLIISRYPHIKGINFDLPHVVQHAPYYPGVEHVGGDMFSSVPKGDAIFMKWILHDWSDEHCLKLLKNCYDATSNEGKVIVVEAILPFTPEIGTSAKSTCQLDVLIMTQYPGGKERKEQEFQALATKAGFSGIRYECLVCNFWVMEFFK
>Casgl305S14678
MDSAENQSDQRHINKEDDDACLYAMHLPHSFVLISVLNAAVELKLFDIIAQASPDACMSPSEIASQLPTRNPHAAALLDRMLRLLASYSLLTCSVQTSEDGKVQRLYGLSPAGKFYVQTGEGCSLAPMTLFACKRMKAEIWDHLKDVILDEGNLSEMVYRKSAFHSMDADPALNKLFNNAMAENSAIATTKVLEAYKGFEGVSLLVDVGGGTGATLNMILSKYPSIKGINFDLPRVIKNAPSYTGIEHVEGDMFVDIPKGDAIILKTICHDWNDEYCIKLLKNCNKALAQNGKVIVIDYIMPEAPEANIDSKFLSIIDNVLGFSLGGRERTVDEFMALSKSSGFSDFQVICRAYNINMGSPENLKDECRINKEEDDACLNAMQLPHSFVLTPVLNAAVELKLFDIIAQASPDSCMSPSEIASQLPTRNPHAAALLDRMLRLLASYSLLTCSLQTSEDGKFQRLYGLSPGGKLYVQNGDGCSLASMIQFACKRMKAEIWYNLKDVILDEGNLSKMVYEKSAFQSMDVDPELNKIFNYAMAENSAIAMTKVLETYKGFERISLLVDVGGGTGATLNMINSKYPSIKGINFDLPRVIKHASSYPGIEHVEGDMFVNVPKGDAIILKSICHDWNDEYCIKLLKNCNEALEQGGKVIVIDYIMPEAPQDNMASRYVSIMDNVIGFSLGGRERTVNEFMALSKSSGFSGFQVICCACNVMGVMELHK
>Casgl241S00937
MGSIRNQSNEPSNDENDDDACLYAMHLPTSYVLPSVLKAAVELNLFDIIAGAGPDACISAPEIASHLPTKNPDAAFLLDRMLRLLASYSLLTCSVCTGDEGRVQRLYGLSPAGKFYVQNGCGCSLNSLALFTLNRLETEVWLQLKDAILEEGNLFERVYGKSIFHCMNADPALNRLFSKAMADLSGITMTKVLEVYKGFEGVSLLVDVAGGTGATLRMILSKYPSIKGINFDLPQVIKHAPSYPDIEHVEGDMFVSVPKGDAILLKFICHDWSDEHCLKLLNNCNEALQQSGKVIVIDYIMSEAPESSVAAKHVSILDNLMAFNLGGKERTVKEFEALSKSSGFSGFNVSCCAYNVLGVMELHK
>Casgl256S12822
MQQQQQAEAKFESAEFDSMISSLSCLVYVRIKFRLIPLRIELEIDPTRISYVNMDSTGNQRDERRINKEDDDACLYAMLLPLSSVLPVVLNAAIELNLFDIIAQASPDACMSPSEIASQLPTRNPHAAALVDRMLRLLASFSLLTCSVQTSEDGKVQRLYGLSPAGKFYVQNGDGCSLASMTLCACKRMKAEIWDHLKDVVLDEGNRSQMVFGKYLFHSMDADPTLNKLFNDAMAEVSTIAMTKVLETYNGFDGISLLVDVGGGTGATLNMILGRYPSIKGINFDLPRVIEHAPSYPGIEHVEGDMFVSIPKADAIILKSICHDWNDEHCIRLLKNCNKALEKDGKVIVIDYIIPEAPESSIASKYVSIMDNIMAFDFGGRERTEKELMALSKSSGFSGFQVICRAHGFLGVMEFQK
>Casgl825S06087
MSSSDQPSRDPVTHEQEQERRGDEEEDEDGEVERLYGTGFICKFLVKNPHGGSVGPLFLLHHHKVFMESWVYGMTAFEYPGTDERFNRVFDQAMSNHITFIMKKRLEVYKRFEGLQVGGGIGVYP
>Casgl182S10650
MSSSDQPSRDPVTHEQELGGEEEEEVGKLAVRLANAVVLPMVLKSALELGLIDIISNAGVGVFLSPPEIASQLPTKNPDGPVLLDRMLRLLASYSILKCLVVTREDGEVERLYGAGPICKFLVKNPHGGSVAPLFLLHHDKFILLRYHLNDVILEGGIPFNRAYGMTAFEYPGTDERFNRVFNQAMSNHTTLIMKKILDVYKGFEGLQVLVDVGGGIGVTLNLITSKYPQIKGFNFDLPHVLADAPSYPGVEHVGGDMFDSVPRGDAIFMKWILHDWSDEHCLKLLKNCWKALPNSGKVIIVESILPVDPENKVSSNIVFEQDLFMLAQNPGGKERTQKEFEALAAKSGFSGFEVEFGCNNSSFQSYAVGKTAGSVQPNRDPVTHEQELGEEEEVGKLAVPSVGALVLPMVLKSALELNPVDIISDAGVGVFLSPSEIANRLPTKNSDTPVLLDRMLRLLRSHSLPPALPKMSSSDQPSRDPVTHERELGEEEEVGKLAVRLANAVVLPMVLKSALELNLIDIISNAGVGVLLSPPEIASRLPTKNPDGPVLLDRMLCLLASYSILKCSLVTREDGEVERLYGAGPICKFLVKNPHEGSVAPLFLLHHDKFIQLRYHLNDAILEGRIPFNRAYGMTAFEHPGTDERFNRVFNQAMSNHTTLIMKKILEAYKGFEGLQVLVDVGGGIGVTLNLITSKYPQIKGFNFDLPHVLADAPSYPGVEHVGGDMFDSVPRGDVIFMKWILHARNDEHCMKLLKNCWKALPNSGKVIIVESILPVDPENKVSSNIVFEQDLFMLAQCPGGKERTQKEFEALAAKSGFSGFEVWSILEEICFIAFPEDTRNDEHCLKLLKNCWKALPNSGKVIIVESILPVDPENKVSSNIVFEQDLFMLAQYPGAKERTQKVFKALAAKSGFSSFQIVSCAYNSWVMEFHNSDQPNRDPVTHQRELEEDEEVGKLAVRLANTVVLPMVLKSALELNLIDIIADAGTGVFLSPSEIASRLPTKNPDAPVLLDRMLRLLASYSILKCSLVTGEDGEVERLYGAGPICKFLVRNTHGGSLGPLLLLLHDKVFMESWYHLNDVILEGGIPFNRAYGMTAFEYPGTDERFNRLFNQAMSNQTTLVVKKILDVYKGLEGLQSLVDVGGGIGVALKLITSKYPQIKGINFDLPHVLADAPSYPGVKHVGGDFFDCVPRGDAIFMKWILHDWSDEHCLKLLKNCWKALPNSGKVIIVESLLPVDPENKVMSHIVFKQDLFMLAQNPGGKERTQKEFEALAAKSGFSGFEVICCAYNSWVMEFHKRADP
>Casgl21S24491
MNNAANTLRGHLKDVILDEGNLFEMVHEKHDFDSLDANPTLNKYFNNAMVKDSTIAMNRVLEAYKRFEVVSLLVDVEGIEHVINEDFSLKVTCLSTSQKGMDAC
>Casgl94S06210
MGSSGETQMTPTQVSDEEANLFAMQLASASVLPMVLKSAIELELLEIMAKAGPGAYLAPSEIAAQLPTRNPDAPVVLDRMLRLLASYSILTYSLRTLPDGRVERLYGLGPVCKFLTKNEDGVSIAPLCLMNQDKVLMESWFYLKDAVLEGGIPFNKAHGTTSFEYHGKDLRFNKVFNKGMSDHSTITMKKLLETYKGFEGLKSVVDVGGGTGAVLSMIVSKYPSIKGINFDLPHVIEDAPSYPGVEHVGGDMFVSIPKGEAIFMKWICHDWSDEHCLKFLKNCYAALPDDGKVIVAECILPVAPDTSLAAKGVIHIDVIMLAHNPGGKERTEKEFEALAKGAGFQGFRVMGCAFNTYIMEFLKRP
>Casgl391S16963
MERQIGKAIMEDQEDNLAGHAMQLVSASVLPMVLKAATELGLLEIMERAGPGALLSSSQIASQLPTHNNADSSLLLDSMLRLLASHSILSCSTSIHQNDGHVLRLYGLAPLSKFFLRNQDGGSLAPLLNLIHDKAIMNIWYHLKDAVLEGELPFYKAHGMQAIEYVGKDARFSNVFKGSMKDFNPLLIMKILETYKGFEGLKSLVDAGGGDGSILKMILSKYPTIKGVNFDLASVIEESPSSLGIEPISGDMFVSIPKGNAILMKCILHHWDDEDCLKVLKNCYEALPDQGKVIVIEMVIPEGAADADKSLFQFHLFMLNMNVNGKERTGKEFDSLARQAGFSGAQVACHAYDFLVVEFYKNM
MNLKKCSQLDDFLQRTLHNWSDEWCLKLLRNCYNTNPKGEKAIIVKAVASMMPKITSAAHIKCQMDMLLMTQIGGKEKTMNELHGMAYEAGFSSIKYMCFVCNFAVMEFLM
>Casgl31S15449
MASPLTSTSRVLDDDGKEEESFLYAMQVATSVVMPMAMQSAVELGVFEILAKAGPGAKLSPSQIVEQMPTKNPEAPVMLDRILRMLATHSLLACSVVADDCGSYQRLYSLSPMSKHFVFDEDGVSLGPFMALIQDKVFLDSWSQLKDAILEGGIPFNRFHGMHAFDYPGIDPRFNQVFNKRCSTRPLRRSLSLIGVLNINQLVDVVGNLGVTLNLIISRYPHIKGINFDLPHVVQHAPYYPGVEHVGGDMFSSVPKGDAIFMKWILHDWSDEHCLKLLKNCYDATSNEGKVIVVEAILPFTPEIGTSAKSTCQLDVLIMTQYPGGKERKEQEFQALATKAGFSGIRYECLVCNFWVMEFFK
>Casgl305S14678
MDSAENQSDQRHINKEDDDACLYAMHLPHSFVLISVLNAAVELKLFDIIAQASPDACMSPSEIASQLPTRNPHAAALLDRMLRLLASYSLLTCSVQTSEDGKVQRLYGLSPAGKFYVQTGEGCSLAPMTLFACKRMKAEIWDHLKDVILDEGNLSEMVYRKSAFHSMDADPALNKLFNNAMAENSAIATTKVLEAYKGFEGVSLLVDVGGGTGATLNMILSKYPSIKGINFDLPRVIKNAPSYTGIEHVEGDMFVDIPKGDAIILKTICHDWNDEYCIKLLKNCNKALAQNGKVIVIDYIMPEAPEANIDSKFLSIIDNVLGFSLGGRERTVDEFMALSKSSGFSDFQVICRAYNINMGSPENLKDECRINKEEDDACLNAMQLPHSFVLTPVLNAAVELKLFDIIAQASPDSCMSPSEIASQLPTRNPHAAALLDRMLRLLASYSLLTCSLQTSEDGKFQRLYGLSPGGKLYVQNGDGCSLASMIQFACKRMKAEIWYNLKDVILDEGNLSKMVYEKSAFQSMDVDPELNKIFNYAMAENSAIAMTKVLETYKGFERISLLVDVGGGTGATLNMINSKYPSIKGINFDLPRVIKHASSYPGIEHVEGDMFVNVPKGDAIILKSICHDWNDEYCIKLLKNCNEALEQGGKVIVIDYIMPEAPQDNMASRYVSIMDNVIGFSLGGRERTVNEFMALSKSSGFSGFQVICCACNVMGVMELHK
>Casgl241S00937
MGSIRNQSNEPSNDENDDDACLYAMHLPTSYVLPSVLKAAVELNLFDIIAGAGPDACISAPEIASHLPTKNPDAAFLLDRMLRLLASYSLLTCSVCTGDEGRVQRLYGLSPAGKFYVQNGCGCSLNSLALFTLNRLETEVWLQLKDAILEEGNLFERVYGKSIFHCMNADPALNRLFSKAMADLSGITMTKVLEVYKGFEGVSLLVDVAGGTGATLRMILSKYPSIKGINFDLPQVIKHAPSYPDIEHVEGDMFVSVPKGDAILLKFICHDWSDEHCLKLLNNCNEALQQSGKVIVIDYIMSEAPESSVAAKHVSILDNLMAFNLGGKERTVKEFEALSKSSGFSGFNVSCCAYNVLGVMELHK
>Casgl256S12822
MQQQQQAEAKFESAEFDSMISSLSCLVYVRIKFRLIPLRIELEIDPTRISYVNMDSTGNQRDERRINKEDDDACLYAMLLPLSSVLPVVLNAAIELNLFDIIAQASPDACMSPSEIASQLPTRNPHAAALVDRMLRLLASFSLLTCSVQTSEDGKVQRLYGLSPAGKFYVQNGDGCSLASMTLCACKRMKAEIWDHLKDVVLDEGNRSQMVFGKYLFHSMDADPTLNKLFNDAMAEVSTIAMTKVLETYNGFDGISLLVDVGGGTGATLNMILGRYPSIKGINFDLPRVIEHAPSYPGIEHVEGDMFVSIPKADAIILKSICHDWNDEHCIRLLKNCNKALEKDGKVIVIDYIIPEAPESSIASKYVSIMDNIMAFDFGGRERTEKELMALSKSSGFSGFQVICRAHGFLGVMEFQK
>Casgl825S06087
MSSSDQPSRDPVTHEQEQERRGDEEEDEDGEVERLYGTGFICKFLVKNPHGGSVGPLFLLHHHKVFMESWVYGMTAFEYPGTDERFNRVFDQAMSNHITFIMKKRLEVYKRFEGLQVGGGIGVYP
>Casgl182S10650
MSSSDQPSRDPVTHEQELGGEEEEEVGKLAVRLANAVVLPMVLKSALELGLIDIISNAGVGVFLSPPEIASQLPTKNPDGPVLLDRMLRLLASYSILKCLVVTREDGEVERLYGAGPICKFLVKNPHGGSVAPLFLLHHDKFILLRYHLNDVILEGGIPFNRAYGMTAFEYPGTDERFNRVFNQAMSNHTTLIMKKILDVYKGFEGLQVLVDVGGGIGVTLNLITSKYPQIKGFNFDLPHVLADAPSYPGVEHVGGDMFDSVPRGDAIFMKWILHDWSDEHCLKLLKNCWKALPNSGKVIIVESILPVDPENKVSSNIVFEQDLFMLAQNPGGKERTQKEFEALAAKSGFSGFEVEFGCNNSSFQSYAVGKTAGSVQPNRDPVTHEQELGEEEEVGKLAVPSVGALVLPMVLKSALELNPVDIISDAGVGVFLSPSEIANRLPTKNSDTPVLLDRMLRLLRSHSLPPALPKMSSSDQPSRDPVTHERELGEEEEVGKLAVRLANAVVLPMVLKSALELNLIDIISNAGVGVLLSPPEIASRLPTKNPDGPVLLDRMLCLLASYSILKCSLVTREDGEVERLYGAGPICKFLVKNPHEGSVAPLFLLHHDKFIQLRYHLNDAILEGRIPFNRAYGMTAFEHPGTDERFNRVFNQAMSNHTTLIMKKILEAYKGFEGLQVLVDVGGGIGVTLNLITSKYPQIKGFNFDLPHVLADAPSYPGVEHVGGDMFDSVPRGDVIFMKWILHARNDEHCMKLLKNCWKALPNSGKVIIVESILPVDPENKVSSNIVFEQDLFMLAQCPGGKERTQKEFEALAAKSGFSGFEVWSILEEICFIAFPEDTRNDEHCLKLLKNCWKALPNSGKVIIVESILPVDPENKVSSNIVFEQDLFMLAQYPGAKERTQKVFKALAAKSGFSSFQIVSCAYNSWVMEFHNSDQPNRDPVTHQRELEEDEEVGKLAVRLANTVVLPMVLKSALELNLIDIIADAGTGVFLSPSEIASRLPTKNPDAPVLLDRMLRLLASYSILKCSLVTGEDGEVERLYGAGPICKFLVRNTHGGSLGPLLLLLHDKVFMESWYHLNDVILEGGIPFNRAYGMTAFEYPGTDERFNRLFNQAMSNQTTLVVKKILDVYKGLEGLQSLVDVGGGIGVALKLITSKYPQIKGINFDLPHVLADAPSYPGVKHVGGDFFDCVPRGDAIFMKWILHDWSDEHCLKLLKNCWKALPNSGKVIIVESLLPVDPENKVMSHIVFKQDLFMLAQNPGGKERTQKEFEALAAKSGFSGFEVICCAYNSWVMEFHKRADP
>Casgl21S24491
MNNAANTLRGHLKDVILDEGNLFEMVHEKHDFDSLDANPTLNKYFNNAMVKDSTIAMNRVLEAYKRFEVVSLLVDVEGIEHVINEDFSLKVTCLSTSQKGMDAC
>Casgl94S06210
MGSSGETQMTPTQVSDEEANLFAMQLASASVLPMVLKSAIELELLEIMAKAGPGAYLAPSEIAAQLPTRNPDAPVVLDRMLRLLASYSILTYSLRTLPDGRVERLYGLGPVCKFLTKNEDGVSIAPLCLMNQDKVLMESWFYLKDAVLEGGIPFNKAHGTTSFEYHGKDLRFNKVFNKGMSDHSTITMKKLLETYKGFEGLKSVVDVGGGTGAVLSMIVSKYPSIKGINFDLPHVIEDAPSYPGVEHVGGDMFVSIPKGEAIFMKWICHDWSDEHCLKFLKNCYAALPDDGKVIVAECILPVAPDTSLAAKGVIHIDVIMLAHNPGGKERTEKEFEALAKGAGFQGFRVMGCAFNTYIMEFLKRP
>Casgl391S16963
MERQIGKAIMEDQEDNLAGHAMQLVSASVLPMVLKAATELGLLEIMERAGPGALLSSSQIASQLPTHNNADSSLLLDSMLRLLASHSILSCSTSIHQNDGHVLRLYGLAPLSKFFLRNQDGGSLAPLLNLIHDKAIMNIWYHLKDAVLEGELPFYKAHGMQAIEYVGKDARFSNVFKGSMKDFNPLLIMKILETYKGFEGLKSLVDAGGGDGSILKMILSKYPTIKGVNFDLASVIEESPSSLGIEPISGDMFVSIPKGNAILMKCILHHWDDEDCLKVLKNCYEALPDQGKVIVIEMVIPEGAADADKSLFQFHLFMLNMNVNGKERTGKEFDSLARQAGFSGAQVACHAYDFLVVEFYKNM
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University