Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Casuarina glauca
Species name
Swamp oak (Casuarina glauca) is a species of eudicot in the family Casuarinaceae.
Species info
Gene sequence info
Casuarina_glauca.CHS.fa
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>Casgl74S21718
MASVEEIFRNQRAQTPAAVLAIGTANPSNCIYQDDFPDFYFRVTKSEHMTELKRRFKRICEKSMIKKRYMHLTEDILNENPNMCTFMEPSLDARQEISVAELPKLAKEAASKAIKEWGQPKSMITHLVFSTTLGTSDMPGADSQLVKLLGLPPSVRRIMMYQHGCFGGGTVLRVAKDFAENHKGARVLAVCAEITASCLRGPSEAHLDSLVGQSLFGDGAAAVIVGADPDTSIERPLFQIVSATQTLLPDSSDVVQGHMLERGLTFHLLRDLPKLASTNMEKCLVESFTPMGISDWNSLFWIVHPGGPAILDQVQARLGLEEDKLKTSRHVLSEYGNMSTACVLFILDEIRKRSMEEGKATTGGGLEWGVLFGLGPGLTVETVVLHSVPLETIH
>Casgl74S21717
MASVEEIRKAQRANGPATVLAIGTATPPNCVSQEEYPDYYFRITNSEHMTDLKEKFKRMCDKSMIKKRYMHLTEEILKDNPKMCEYMAPSLDARQDMVVVEVPKLGKEAASKAIKEWGQSKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDSHLDSLVGQALFGDGAAAVIVGADPDTSVERPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGIISKNIEKSLAEAFSPLGISDWNSLFWIAHPGGPAILDQVEAKLGLKEEKLRATRHILSEYGNMSSACVLFILDEMRKSSLEQGKPTTGEGLEWGVLFGFGPGLTVETVVLHGVPVTAGTVH
>Casgl74S21661
MASVEEIFRNQRAQTPAAILAIGTANPSNCIYQDDFPDFYFRVTKSEHMTDLKKRFKRICEKSMIKKRYMHLTEDILNENPNMCTFMEPSLDARHDISVAELPKLAKAAASKAIKEWGQPKSMITHLVFSTTLGTSDMPGADSQLVKLLGLPPSVRRIMMYQHGCFGGGTVLRVAKDFAENHKGARVLAVCAEITASCLRGPSEAHLDSLVGQSLFGDGAAAVIVGADPDTSIERPLFQIVSATQTLLPDSNAVVQGHMLERGLTCHLLRDLPKLASTNMEKCLVESFTPMGISDWNSLFWIVHPGGPAVLDQVQARLGLEEDKLKTSRYVLSEYGNMSAACVLFILDEMRKRSMEEGKATTGGGMDWGVLFGLGAGLTVETVVLHSVPLETIH
>Casgl46S18248
MVTVEEVRKAQRAEGPATVLAIGTATPPNCIDQSTYPDYYFRITNSEHKTELKEKFQRMCDKSMIKKRYMYLTEEILKEHPNMCAYMAPSLDARQDMAVVEIPKLGKEAAVKAIKEWGQPKAKITHLVFCITSGVDMPGADYQLTKLLGLSPSVKRLMMYQQGCFAVGTVLRLAKDLAENNRGARVLVVCSENTAVTFRGPSDTHLDSLVGQALFGDGASAIIVGADPLPEVEKPLFEVISAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFQPLGISDWNSLFWIAHPGGPAILDQVEEKLAIKPEKLGATRHVLSEYGNMSSACVLFILDEMRRKAAEKGLKTPGEGLDWGVLFGFGPGLTVETIVLHSLTT
>Casgl46S05380
MVTVEEVRKAQRAEGPATVLAIGTATPPNCLDQSTYPDYYFRITNSEHKTELKEKFQRMCDKSMIKKRYMYLTEEILKEHPNMCAYMAPSLDARQDMVVVEIPKLGKEAAVKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAIIVGADPLPEVEKPLFEVVSTAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFQPLGISDWNSLFWIAHPGGPAILDQVEEKLALKPEKLGATRHVLSEYGNMSSACVLFILDEMRRKSAEKGLKTTGEGLDWGVLFGFGPGLTVETVVLHSLTT
>Casgl132S03461
MSGINGNGAPNKYPADSRSVPTPGKATVLALGKAFPSQLIPQECLVEGYIRDTKCVDLSIKEKLDRLCKTTTVKTRYTVMSKEILDKHPELATEGSSTIKQRLEIANPAVLQMAKEASLSCIKEWGRPAQDITHIVYVSSSEIRLPGGDLYLASQLGLRSDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLITTSETTILGFRPPNKERPYDLVGAALFGDGAAAVIIGANPIAGQESPFMELNYAVQQFLPGTHNVIDGKLSEEGINFRLGRDLPQKIEENIEEFCKKLMAKADLEEFNDLFWAVHPGGPAILNRLENTLKLTSDKLECSRRALMDYGNVSSGTIFYVMDYMREEQKRGRQEWGLALAFGPGITFEGILIRSL
>Casgl173S03857
MGSEGVPRGGSTKMANPGKATILALGKAFPHQLVMQEYLVDGYFRDTNCDDPLLKQKLTRLCKTTTVKTRYVVMSEEILKKYPELSVEGLPTVKQRLDICNEAVTRMAVEASQACIKTWGRPISEITHLVYVSSSEARLPGGDLYLAKGLGLSPETQRVMLYFMGCSGGVSGLRVAKDIAENNPGSRVLLATSETTIIGYKPPSAERPYDLVGVALFGDGAGAMIIGSDPIMGNEKPLFELHTAIQHFLPDTEKTIDGRLTEEGISFKLARELPQIIEDNIEGFCKKLTKVTGLPEKDYNSMFWAVHPGGPAILNRMEKRLDLSPEKLNASRRALMDYGNASSNTIVYVLEYMIEECLKTKKENKGDNEWGLILAFGPGITFEGILARNLTV
MASVEEIFRNQRAQTPAAVLAIGTANPSNCIYQDDFPDFYFRVTKSEHMTELKRRFKRICEKSMIKKRYMHLTEDILNENPNMCTFMEPSLDARQEISVAELPKLAKEAASKAIKEWGQPKSMITHLVFSTTLGTSDMPGADSQLVKLLGLPPSVRRIMMYQHGCFGGGTVLRVAKDFAENHKGARVLAVCAEITASCLRGPSEAHLDSLVGQSLFGDGAAAVIVGADPDTSIERPLFQIVSATQTLLPDSSDVVQGHMLERGLTFHLLRDLPKLASTNMEKCLVESFTPMGISDWNSLFWIVHPGGPAILDQVQARLGLEEDKLKTSRHVLSEYGNMSTACVLFILDEIRKRSMEEGKATTGGGLEWGVLFGLGPGLTVETVVLHSVPLETIH
>Casgl74S21717
MASVEEIRKAQRANGPATVLAIGTATPPNCVSQEEYPDYYFRITNSEHMTDLKEKFKRMCDKSMIKKRYMHLTEEILKDNPKMCEYMAPSLDARQDMVVVEVPKLGKEAASKAIKEWGQSKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDSHLDSLVGQALFGDGAAAVIVGADPDTSVERPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGIISKNIEKSLAEAFSPLGISDWNSLFWIAHPGGPAILDQVEAKLGLKEEKLRATRHILSEYGNMSSACVLFILDEMRKSSLEQGKPTTGEGLEWGVLFGFGPGLTVETVVLHGVPVTAGTVH
>Casgl74S21661
MASVEEIFRNQRAQTPAAILAIGTANPSNCIYQDDFPDFYFRVTKSEHMTDLKKRFKRICEKSMIKKRYMHLTEDILNENPNMCTFMEPSLDARHDISVAELPKLAKAAASKAIKEWGQPKSMITHLVFSTTLGTSDMPGADSQLVKLLGLPPSVRRIMMYQHGCFGGGTVLRVAKDFAENHKGARVLAVCAEITASCLRGPSEAHLDSLVGQSLFGDGAAAVIVGADPDTSIERPLFQIVSATQTLLPDSNAVVQGHMLERGLTCHLLRDLPKLASTNMEKCLVESFTPMGISDWNSLFWIVHPGGPAVLDQVQARLGLEEDKLKTSRYVLSEYGNMSAACVLFILDEMRKRSMEEGKATTGGGMDWGVLFGLGAGLTVETVVLHSVPLETIH
>Casgl46S18248
MVTVEEVRKAQRAEGPATVLAIGTATPPNCIDQSTYPDYYFRITNSEHKTELKEKFQRMCDKSMIKKRYMYLTEEILKEHPNMCAYMAPSLDARQDMAVVEIPKLGKEAAVKAIKEWGQPKAKITHLVFCITSGVDMPGADYQLTKLLGLSPSVKRLMMYQQGCFAVGTVLRLAKDLAENNRGARVLVVCSENTAVTFRGPSDTHLDSLVGQALFGDGASAIIVGADPLPEVEKPLFEVISAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFQPLGISDWNSLFWIAHPGGPAILDQVEEKLAIKPEKLGATRHVLSEYGNMSSACVLFILDEMRRKAAEKGLKTPGEGLDWGVLFGFGPGLTVETIVLHSLTT
>Casgl46S05380
MVTVEEVRKAQRAEGPATVLAIGTATPPNCLDQSTYPDYYFRITNSEHKTELKEKFQRMCDKSMIKKRYMYLTEEILKEHPNMCAYMAPSLDARQDMVVVEIPKLGKEAAVKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAIIVGADPLPEVEKPLFEVVSTAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFQPLGISDWNSLFWIAHPGGPAILDQVEEKLALKPEKLGATRHVLSEYGNMSSACVLFILDEMRRKSAEKGLKTTGEGLDWGVLFGFGPGLTVETVVLHSLTT
>Casgl132S03461
MSGINGNGAPNKYPADSRSVPTPGKATVLALGKAFPSQLIPQECLVEGYIRDTKCVDLSIKEKLDRLCKTTTVKTRYTVMSKEILDKHPELATEGSSTIKQRLEIANPAVLQMAKEASLSCIKEWGRPAQDITHIVYVSSSEIRLPGGDLYLASQLGLRSDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLITTSETTILGFRPPNKERPYDLVGAALFGDGAAAVIIGANPIAGQESPFMELNYAVQQFLPGTHNVIDGKLSEEGINFRLGRDLPQKIEENIEEFCKKLMAKADLEEFNDLFWAVHPGGPAILNRLENTLKLTSDKLECSRRALMDYGNVSSGTIFYVMDYMREEQKRGRQEWGLALAFGPGITFEGILIRSL
>Casgl173S03857
MGSEGVPRGGSTKMANPGKATILALGKAFPHQLVMQEYLVDGYFRDTNCDDPLLKQKLTRLCKTTTVKTRYVVMSEEILKKYPELSVEGLPTVKQRLDICNEAVTRMAVEASQACIKTWGRPISEITHLVYVSSSEARLPGGDLYLAKGLGLSPETQRVMLYFMGCSGGVSGLRVAKDIAENNPGSRVLLATSETTIIGYKPPSAERPYDLVGVALFGDGAGAMIIGSDPIMGNEKPLFELHTAIQHFLPDTEKTIDGRLTEEGISFKLARELPQIIEDNIEGFCKKLTKVTGLPEKDYNSMFWAVHPGGPAILNRMEKRLDLSPEKLNASRRALMDYGNASSNTIVYVLEYMIEECLKTKKENKGDNEWGLILAFGPGITFEGILARNLTV
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University