Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Casuarina glauca
Species name
Swamp oak (Casuarina glauca) is a species of eudicot in the family Casuarinaceae.
Species info
Gene sequence info
Casuarina_glauca.4CL.fa
Download
>Casgl10S06383
METHGQNLAEDDEYIFRSRYPAVPVPDITLPEFVLQDAESYAEKVAFVEAVTGKEVTYGDVVRDTRRFSKALRSLGLLKGHVIIVVLPNVAEYAIVALGIMAAGGIFSGANPAAHASEIKKQVEAAEAKLIVTNGPSYEKVKGLGLPVIILGEEPIDGAMNWNKLLEAADRAGTSSVQVDVQQTDLCALPFSSGTTGLSKGVMLTHQNLVANLCSTLFSVAPEMVGQVTTLGVIPFFHIYGITGICCATLRNKGKVVVMGRFELRTFLNALITQEVTFAPIVPPIILQLVKNPVVEEFDLSRLKLQAIMSAAAPLAPELLSAFENKFPGVQVQEAYGLTEHSCITLTLADPETGHRLAKKNSVGFILPNLEVKFIDPDTGRSLPRNTPGEICVRSQCVMQGYYNNKEETALTIDDQGWLHTGDVGFIDDEGNVFVMDRIKELIKYKGFQVAPAELEAILLSHSSVEDAAVVPLPDEEAGEIPAASVVLAAGAKESEQDIIHHVASNVANYKKVRVVHFVDTIPKSPSGKIMRRRIREKMIEKMRANLQTKPNPIFK
>Casgl182S10594
MISVASNSVEAQNQELSPKVVSKESQKTEDVHVFKSKLPDIPVSNHLSLHSYCFEYLAEFSDRPCLIVGSTGKKYSFAETHRISQKVAAGLSNLGIKKGDVIMVLLQNSAEFAFSFLGASMLGAVTTTANPFYTSAEVFKQFSSAGAKLIITQSQYVDKLRETGDNFPKFGDDFQVITVDDPPEKCLHFSVLSEANESDLPSVSIDPNDPVALPFSSGTTGLPKGVVLTHKSLITSVAQQVDGENPNLYLKPEDVVLCVLPLFHIYSLNSVLLCSLRAGSAVLLMQKFEIGSLLDLIQQHRVSVAAVVPPLVLALAKNPIVTNFDLRSIRMVLSGAAPLGKELEEALRSRVPQAILGQGYGMTEAGPVLSMCLAFAKQPFPTKSGSCGTVVRNAELKVIDPETGCSLGHNKPGEICIRGSQIMKEYLNDAQATAATIDVDGWLHTGDIGYVDDDEEIFIVDRVPPAELEALLVSHSSIADAAVVPQKDDAAGEVPVAFVVRSNGFELTEEAVKEFIAKQVVFYKRLHKVYFVHAIPKSPSGKILRKDLRAKLAAAAAASPKS
>Casgl43S05252
MPFYAVHLELRGSHLQVSQAHTKAYANQVEAGTDPSSPLLVLTDPGYGMTETFGITALENPEEESPLSGSIGTLVPGVECRVVNTDTLKPLPFLRTTGRNMASRT
>Casgl43S17780
MQGYFNNPEATKITIDENGWVHTGDLGYFNEEGQLFVVDRCKELIKCHGFQVPPAELEGLLLSHNEIVDAAVPIAYVVRLPNSLLTEEYVKQFIAKQGVRQSSDIPQNFARNFERLHYKRLRKVTFVSSIPKSTSGKILRRELKEKVRSKI
>Casgl43S17781
MRNEASSRSMGKSFNPKTQTYSSPRPPLPLPTIPSLSLTSVLFQSNSSSPENLALVDADSGETLSFDQLRLHVSKLAHSLLQLNIDKHDVVLIVAPNSIHFPVCFLAVVAIGAVVSTCNPSYTISELSKQVSDCNPKLLITVPELWDKVEHFDLPSIMLNSSNSANCKRPAPSDSKMWHYSELIKANRACDLPAKNIKQSDIAAVLYSSGTTGTSKGVILTHKNFIAAALMRTADPERYAEPKRVYLCFLPMFHVFGLAVTAYSQLRGGNTVVSMAKFELERVLEAVEKYRVTHLPVVPPVMILLAKHRALKKYDLSSLKQIASGAAPLGKDVMEESAKNFPHVDIAQGYGMTETCGVITMKNPREEPRHSGSAGTLISAVEAQIVDSGTQKRLPPNQSGEIWVRGPNVMQGYLNNPEATKLILDGQQWLRTGDLGYFNEEGQLFVVDRMKELIKCYGFQVAPAELEGLLLSHNEISDAAVIPFPDTKAGEVPIAYVVRSRNSLLTEEDVKKFVASKVAPFKRLRAVTFVNSLPKSPSGKILRRQIVEKCFNPETQIYSSPRPPIHLPTNPDLSLTSFLFQTNSSSPHDLALIDADTGETLSFDQLRLHVSKFAHSLLQLNIDKHDVILIVAPNSIQFPVCFLAIVTIGAVVSTCNPSYTISELSKQVSDCKPKLVITVPELWDKVKEFDLPSIMLSSSSSTDFKQTETSNRKIWHYSELIRSSEFCNLPAKNIKQSDIAALLYSSGTTGTSKGVILTHKNFIATSLMVGAGQDLYEEPKRVYLCFLPMFHVFGLAVIAYASLRGGNTVVSMRKFELERVLGAVEKYRVTHLAVVPPVMILLAKHSALKKYDLSSLKRIGSGAAPLGKDVIEESAKNIPHAEVGQGYGMTETCGIISEENPTDEPPLSGSAGTLAPGVEAQIVSPETLKPLPPNQLGEIWVRGPNMMQGYLKNPEATKQTIDGQGWVHTGDLGYFNEVGQLFVVDRMKELIKCYGFQVAPAELEGLLLSHNEILDAVVIPLPDTKAGEVPIAYVVRSQNSLLTEEDVQKFVATKVAPYKRLRAVTFVESVPKSASGKILRRQIMEKPRLRSPFLKQTN
>Casgl43S17782
MVEAKELMIASDGYGMTETCGIISLENPQEESAFSGSPGTLVLGVESRIVNTDTLKPLPTGPRPAPAPPPHQYDARGRDVNPKWPTCQSLENVSRLDNPEATKLTIDENGWAHIGDLGYFNEKGQLFIVERIKELIKCHDFQIENCLTREMFVNLPPTKYAKQIWDNLVRMYGKID
>Casgl550S19708
MSGQNTKPHAPWYSPETGIYHSTYPSVELPSDPFLDVVSFLFSHQHNAGTALIDSSSGSSVSYTELYPLVKSMASGLRNMGVSKGDVAMMLLPNSIYYPIIFLGVLYLGAIVTPMNPLSSVPEVKKQITSCNVRLAFTIPGRVEELQALGIQAIGVPENVNLESKQTSFSDFYKVISGSFDLAPRPVIKQEDTAAILCSSGTTGMSKGVVLTHRNFIAMLELFVRFEASLYDYSSLNNVHLAVLPMFHIYGLAFFVVGLLYLGSCVVVMRKFDVNAVINAIDRYKVTHFPVVPPILTTLTREAKKLSGSRLKSLKQVSCGAAPVSEKAIEDFIQTLPHVDFIQGYGMTETTAVGTRGFNTERFQNYSSIGLLAPSMQAKVVDWETGSSLPPGSTGVLWLRGPGIMKGYLNNTEATMSTIDKDGWLNTGDIGWFDQDGYIYITDRLKELIKYKGFQIAPADLEAVLISHPEILDVGVTAAPDEESGQIPVALVVRKNGSRISPEAIMDYVSGQVAPYRKVRKVIFTNSIPRSSAGKILRRELGSLMSVRL
>Casgl550S19706
MNGQNPNPYPLWYSPETGIYHSKNPSVELPSDPFLDVVTFLFSHQHNAGSALIDSSSGSSISYTELYPLVKSMASGLHNLGVSKGDMVLILLPNSIYYPIIFLGVLYLGAIVTPMNPLSSVLEVQKQITGFNLCLAFTISGRVEELQALGIPAIGVPENVNLDLRQTSFSDFYNLISGSFDLAPRRVIKQEDTAAIMYSSGTTGMSKAVVLTHRNFIAMLELFVRFEASQYEHSSLDNVFLAVLPMFHIYGLSLFVMGLLYLGSCVVVMRKFNINAVINAIDRYKVTHFPVVPPILTTLTREANKLGGSNLKSLKQISCGAAPLSGKAIEDFIQTLPHVDFIQGYGMTETTAVGTRGFNTERFQKYSSIGLLAPNMQAKVVDWKTGFSLPPGSSGELWLRGPGIMKGYLNNMEATMSTIDKDGWLHTGDIAFFDLDGYIHISDRLKELIKYKGFQIAPADLEAVLISHPEILDVAVTAALDEESGEIPVAFVVRKNASRLSPEAVMDYVSEQVAPYKKVRKVVFTNSIPKSPAGKILRRELKNFITSRL
>Casgl238S12206
MAIQTEQQEFIFRSKLPDIYIPKHLPLHSYCFENISKVGTRPCLINGATGEIYTYYDVELTSRKVAAGLHKLGIRKGDVVMLLLPNSPQFAFVFLGASYLGAMTTAANPFFTAAEVSKQAKSSGTKLVITQASYYEKVKEYANETGVKIMCIDSPPEDCLHFSELTQADENDLPEVDISPDDVVALPYSSGTTGFPKGVMLTHKGLVTSVAQQVDGENPNLHFHSEDVILCVLPLFHIYSLNSVFLCGLRAGAAILIMQKFEIVSLLELIQKHKVTVMPAVPPIVLGITKFPDLDKYDLSSIKILKSGGAPLGKEIEETVKARFPNAKFGQGYGMTEAGPVLAMCLAFAKEPFPVKSGACGCVVRNAEMKIVDPETGVSLPRNQSGEICIRGDQIMKGYINDPESTASTIDKQGWLHTGDIGFIDDDDELFIVDRLKELIKYKGFQVAPAELEALLLTHPKISDSAVVPMKDEIAGEVPVAFVTRSNGSQVTEDEIKQFVSKQVVFYKRISRVFFIDAIPKSPSGKILRKDLRAKLAAGI
>Casgl100S06425
MEKSGFGRDGIYRSLRPPLVLPSDPNLSLVTFLFRNASSYPHKPALIDSDSSETLSFSQFKSTVVKISHGLLRLGIRKNDVVLIFAPNSIQFPLCFLGIVAIGAIATTANPVYTVHELAKQVKDSSPKLIITVTELWDKVKDFNLPAVILGSSHSFSSSSSSNIVYFKDLISSGGSESEFPDNNVKQNDTAALLYSSGTTGTSKGVILTHRNFIAASLMVTMDQELSGEAHNVFLCVLPMFHVFGLSVIVYSQLQIGNAVVSMGKFELEGILRAVQRYRVTHLWVVPPIILALAKHSVVKKYNLSSLRHVGSGAAPLGKDLMEECTRNIPQAVVAQGYGMTETCGIVSVENPRVGVRNSGSAGMLAPGVDCQIISVDTLKPLPPNQLGEIWVRGPNMMKGYYNNPQATKLTIDNKGWVHTGDLGYFDGDGQLYVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDAEAGEVPVAYVVRSPSSSLTEEDIMKFIANQVAPFKRLRRVSFINSVPKSASGKILRRELIEKVRSKI
METHGQNLAEDDEYIFRSRYPAVPVPDITLPEFVLQDAESYAEKVAFVEAVTGKEVTYGDVVRDTRRFSKALRSLGLLKGHVIIVVLPNVAEYAIVALGIMAAGGIFSGANPAAHASEIKKQVEAAEAKLIVTNGPSYEKVKGLGLPVIILGEEPIDGAMNWNKLLEAADRAGTSSVQVDVQQTDLCALPFSSGTTGLSKGVMLTHQNLVANLCSTLFSVAPEMVGQVTTLGVIPFFHIYGITGICCATLRNKGKVVVMGRFELRTFLNALITQEVTFAPIVPPIILQLVKNPVVEEFDLSRLKLQAIMSAAAPLAPELLSAFENKFPGVQVQEAYGLTEHSCITLTLADPETGHRLAKKNSVGFILPNLEVKFIDPDTGRSLPRNTPGEICVRSQCVMQGYYNNKEETALTIDDQGWLHTGDVGFIDDEGNVFVMDRIKELIKYKGFQVAPAELEAILLSHSSVEDAAVVPLPDEEAGEIPAASVVLAAGAKESEQDIIHHVASNVANYKKVRVVHFVDTIPKSPSGKIMRRRIREKMIEKMRANLQTKPNPIFK
>Casgl182S10594
MISVASNSVEAQNQELSPKVVSKESQKTEDVHVFKSKLPDIPVSNHLSLHSYCFEYLAEFSDRPCLIVGSTGKKYSFAETHRISQKVAAGLSNLGIKKGDVIMVLLQNSAEFAFSFLGASMLGAVTTTANPFYTSAEVFKQFSSAGAKLIITQSQYVDKLRETGDNFPKFGDDFQVITVDDPPEKCLHFSVLSEANESDLPSVSIDPNDPVALPFSSGTTGLPKGVVLTHKSLITSVAQQVDGENPNLYLKPEDVVLCVLPLFHIYSLNSVLLCSLRAGSAVLLMQKFEIGSLLDLIQQHRVSVAAVVPPLVLALAKNPIVTNFDLRSIRMVLSGAAPLGKELEEALRSRVPQAILGQGYGMTEAGPVLSMCLAFAKQPFPTKSGSCGTVVRNAELKVIDPETGCSLGHNKPGEICIRGSQIMKEYLNDAQATAATIDVDGWLHTGDIGYVDDDEEIFIVDRVPPAELEALLVSHSSIADAAVVPQKDDAAGEVPVAFVVRSNGFELTEEAVKEFIAKQVVFYKRLHKVYFVHAIPKSPSGKILRKDLRAKLAAAAAASPKS
>Casgl43S05252
MPFYAVHLELRGSHLQVSQAHTKAYANQVEAGTDPSSPLLVLTDPGYGMTETFGITALENPEEESPLSGSIGTLVPGVECRVVNTDTLKPLPFLRTTGRNMASRT
>Casgl43S17780
MQGYFNNPEATKITIDENGWVHTGDLGYFNEEGQLFVVDRCKELIKCHGFQVPPAELEGLLLSHNEIVDAAVPIAYVVRLPNSLLTEEYVKQFIAKQGVRQSSDIPQNFARNFERLHYKRLRKVTFVSSIPKSTSGKILRRELKEKVRSKI
>Casgl43S17781
MRNEASSRSMGKSFNPKTQTYSSPRPPLPLPTIPSLSLTSVLFQSNSSSPENLALVDADSGETLSFDQLRLHVSKLAHSLLQLNIDKHDVVLIVAPNSIHFPVCFLAVVAIGAVVSTCNPSYTISELSKQVSDCNPKLLITVPELWDKVEHFDLPSIMLNSSNSANCKRPAPSDSKMWHYSELIKANRACDLPAKNIKQSDIAAVLYSSGTTGTSKGVILTHKNFIAAALMRTADPERYAEPKRVYLCFLPMFHVFGLAVTAYSQLRGGNTVVSMAKFELERVLEAVEKYRVTHLPVVPPVMILLAKHRALKKYDLSSLKQIASGAAPLGKDVMEESAKNFPHVDIAQGYGMTETCGVITMKNPREEPRHSGSAGTLISAVEAQIVDSGTQKRLPPNQSGEIWVRGPNVMQGYLNNPEATKLILDGQQWLRTGDLGYFNEEGQLFVVDRMKELIKCYGFQVAPAELEGLLLSHNEISDAAVIPFPDTKAGEVPIAYVVRSRNSLLTEEDVKKFVASKVAPFKRLRAVTFVNSLPKSPSGKILRRQIVEKCFNPETQIYSSPRPPIHLPTNPDLSLTSFLFQTNSSSPHDLALIDADTGETLSFDQLRLHVSKFAHSLLQLNIDKHDVILIVAPNSIQFPVCFLAIVTIGAVVSTCNPSYTISELSKQVSDCKPKLVITVPELWDKVKEFDLPSIMLSSSSSTDFKQTETSNRKIWHYSELIRSSEFCNLPAKNIKQSDIAALLYSSGTTGTSKGVILTHKNFIATSLMVGAGQDLYEEPKRVYLCFLPMFHVFGLAVIAYASLRGGNTVVSMRKFELERVLGAVEKYRVTHLAVVPPVMILLAKHSALKKYDLSSLKRIGSGAAPLGKDVIEESAKNIPHAEVGQGYGMTETCGIISEENPTDEPPLSGSAGTLAPGVEAQIVSPETLKPLPPNQLGEIWVRGPNMMQGYLKNPEATKQTIDGQGWVHTGDLGYFNEVGQLFVVDRMKELIKCYGFQVAPAELEGLLLSHNEILDAVVIPLPDTKAGEVPIAYVVRSQNSLLTEEDVQKFVATKVAPYKRLRAVTFVESVPKSASGKILRRQIMEKPRLRSPFLKQTN
>Casgl43S17782
MVEAKELMIASDGYGMTETCGIISLENPQEESAFSGSPGTLVLGVESRIVNTDTLKPLPTGPRPAPAPPPHQYDARGRDVNPKWPTCQSLENVSRLDNPEATKLTIDENGWAHIGDLGYFNEKGQLFIVERIKELIKCHDFQIENCLTREMFVNLPPTKYAKQIWDNLVRMYGKID
>Casgl550S19708
MSGQNTKPHAPWYSPETGIYHSTYPSVELPSDPFLDVVSFLFSHQHNAGTALIDSSSGSSVSYTELYPLVKSMASGLRNMGVSKGDVAMMLLPNSIYYPIIFLGVLYLGAIVTPMNPLSSVPEVKKQITSCNVRLAFTIPGRVEELQALGIQAIGVPENVNLESKQTSFSDFYKVISGSFDLAPRPVIKQEDTAAILCSSGTTGMSKGVVLTHRNFIAMLELFVRFEASLYDYSSLNNVHLAVLPMFHIYGLAFFVVGLLYLGSCVVVMRKFDVNAVINAIDRYKVTHFPVVPPILTTLTREAKKLSGSRLKSLKQVSCGAAPVSEKAIEDFIQTLPHVDFIQGYGMTETTAVGTRGFNTERFQNYSSIGLLAPSMQAKVVDWETGSSLPPGSTGVLWLRGPGIMKGYLNNTEATMSTIDKDGWLNTGDIGWFDQDGYIYITDRLKELIKYKGFQIAPADLEAVLISHPEILDVGVTAAPDEESGQIPVALVVRKNGSRISPEAIMDYVSGQVAPYRKVRKVIFTNSIPRSSAGKILRRELGSLMSVRL
>Casgl550S19706
MNGQNPNPYPLWYSPETGIYHSKNPSVELPSDPFLDVVTFLFSHQHNAGSALIDSSSGSSISYTELYPLVKSMASGLHNLGVSKGDMVLILLPNSIYYPIIFLGVLYLGAIVTPMNPLSSVLEVQKQITGFNLCLAFTISGRVEELQALGIPAIGVPENVNLDLRQTSFSDFYNLISGSFDLAPRRVIKQEDTAAIMYSSGTTGMSKAVVLTHRNFIAMLELFVRFEASQYEHSSLDNVFLAVLPMFHIYGLSLFVMGLLYLGSCVVVMRKFNINAVINAIDRYKVTHFPVVPPILTTLTREANKLGGSNLKSLKQISCGAAPLSGKAIEDFIQTLPHVDFIQGYGMTETTAVGTRGFNTERFQKYSSIGLLAPNMQAKVVDWKTGFSLPPGSSGELWLRGPGIMKGYLNNMEATMSTIDKDGWLHTGDIAFFDLDGYIHISDRLKELIKYKGFQIAPADLEAVLISHPEILDVAVTAALDEESGEIPVAFVVRKNASRLSPEAVMDYVSEQVAPYKKVRKVVFTNSIPKSPAGKILRRELKNFITSRL
>Casgl238S12206
MAIQTEQQEFIFRSKLPDIYIPKHLPLHSYCFENISKVGTRPCLINGATGEIYTYYDVELTSRKVAAGLHKLGIRKGDVVMLLLPNSPQFAFVFLGASYLGAMTTAANPFFTAAEVSKQAKSSGTKLVITQASYYEKVKEYANETGVKIMCIDSPPEDCLHFSELTQADENDLPEVDISPDDVVALPYSSGTTGFPKGVMLTHKGLVTSVAQQVDGENPNLHFHSEDVILCVLPLFHIYSLNSVFLCGLRAGAAILIMQKFEIVSLLELIQKHKVTVMPAVPPIVLGITKFPDLDKYDLSSIKILKSGGAPLGKEIEETVKARFPNAKFGQGYGMTEAGPVLAMCLAFAKEPFPVKSGACGCVVRNAEMKIVDPETGVSLPRNQSGEICIRGDQIMKGYINDPESTASTIDKQGWLHTGDIGFIDDDDELFIVDRLKELIKYKGFQVAPAELEALLLTHPKISDSAVVPMKDEIAGEVPVAFVTRSNGSQVTEDEIKQFVSKQVVFYKRISRVFFIDAIPKSPSGKILRKDLRAKLAAGI
>Casgl100S06425
MEKSGFGRDGIYRSLRPPLVLPSDPNLSLVTFLFRNASSYPHKPALIDSDSSETLSFSQFKSTVVKISHGLLRLGIRKNDVVLIFAPNSIQFPLCFLGIVAIGAIATTANPVYTVHELAKQVKDSSPKLIITVTELWDKVKDFNLPAVILGSSHSFSSSSSSNIVYFKDLISSGGSESEFPDNNVKQNDTAALLYSSGTTGTSKGVILTHRNFIAASLMVTMDQELSGEAHNVFLCVLPMFHVFGLSVIVYSQLQIGNAVVSMGKFELEGILRAVQRYRVTHLWVVPPIILALAKHSVVKKYNLSSLRHVGSGAAPLGKDLMEECTRNIPQAVVAQGYGMTETCGIVSVENPRVGVRNSGSAGMLAPGVDCQIISVDTLKPLPPNQLGEIWVRGPNMMKGYYNNPQATKLTIDNKGWVHTGDLGYFDGDGQLYVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDAEAGEVPVAYVVRSPSSSLTEEDIMKFIANQVAPFKRLRRVSFINSVPKSASGKILRRELIEKVRSKI
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University