Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Castanea dentata
Species name
American chestnut (Castanea dentata) is a species of eudicot in the family Fagaceae (beech family).
Species info
Gene sequence info
Castanea_dentata.CHS.fa
Download
>Caden.01G266500.1.v1.1
MASSLDAIRKAQRAEGPATILAIGTATPSNCVSQADYPDYYFRITKSEHMTELKEKFKRMCDKSMIKKRYMHLNEEILNENPKMCEYMAPSLDARQDIVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDSHLDSLVGQALFGDGAAAVIIGADPDTKVERPLFQLVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGIISKNIEKSLVEAFTPIGISDWNSLFWIAHPGGPAILDQVEIKLGLKEEKLRSTRHVLSEYGNMSSACVLFILDEMRKSSAENGKATTGEGLDWGVLFGFGPGLTVETVVLHSVPVETSH
>Caden.02G117400.1.v1.1
MVTVDEVRKLQRAEGPATVMAIGTATPPNCVDQSTYPDYYFRITNSEHKTELKEKFKRMCDKSMIKKRYMYLTEEILKENPHVCEYMAPSLDARQDMVVVEVPRLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAIIIGADPIPEVEKPLFELVSASQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLAEAFQPLGISDWNSLFWIAHPGGPAILDQVELKLGLKPEKMRATRHVLSEYGNMSSACVLFILDEMRKKSKEDGLKTTGEGLEWGVLFGFGPGLTVETVVLHSVSS
>Caden.02G117700.1.v1.1
MVTVDEVRKLQRAEGPATVMAIGTATPPNCVDQSTYPDYYFRITNSEHKTELKEKFKRMCDKSMIKKRYMYLTEEILKENPHVCEYMAPSLDARQDMVVVEVPRLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAIIIGADPIPEVEKPLFELVSASQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLAEAFQPLGISDWNSLFWIAHPGGPAILDQVELKLGLKPEKMRATRHVLSEYGNMSSACVLFILDEMRKKSKEDGLKTTGEGLEWGVLFGFGPGLTVETVVLHSVSS
>Caden.06G159300.1.v1.1
MADEKSEIKKRNLHLTEEFLKKSSSICAYNVPSLDARQDIKIMETPKLGAEAARKAIEEWGQPKSKITHLIFHASSGVDMPGCYADGTILRIAKDLAENNVAARVLAVCSEMTVDSFRGPLDSDMSCLVGQAIFGDGAAALIIGANHDTLLEERPLFELVSAAQTIVPNSEGALEAHLREVGLTFYLSKDLPTLVSNSIKTCLVEAFSELGISDWNSLFWIVHSGGPAILKEIEAKVRLNKEKLRASWHILREYGNMLGTSVFFILDEMRRKSLEEGKSTTGEGLEWGVLFGFGPGVTVETIVLRSVPIITTSP
>Caden.07G170800.1.v1.1
MGSEGIAQECSKKVANPGTATILALGKAFPHQLVMQDYLVDGYFRDTNCDDPVLKQKLTRLCKTTTVKTRYVVMSEEILKKYPELAIEGLPTVKQRLDICNDAVTQMAVEASQACIKNWGRPISDITHLVYVSSSEARLPGGDLYLARGLGLGPEIQRVMLYFMGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSAKRPYDLVGVALFGDGAGAMIIGSDPVLGNEKPLFELHTAIQEFLPETEKTIDGRLTEEGISFKLARELPQIIEDNIEGFCEKLIKVVGFPEKEYNKMFWAVHPGGPAILNRMEKRLELSPEKLNASRRALMDYGNASSNTIVYVLEYMLEESLKIKRENQGDNEWGLILAFGPGITFEGILARNLTV
>Caden.11G176000.1.v1.1
MSRTNGNGTPNHYSAQTRRIPTPGKATVLALGKAFPSQLVPQECLVEGYIRDTKCVDLSVKEKLERLCKTTTVKTRYTVMSKEILDKYPELATEGSPTIKQRLEIANPAVVEMAMEASLACIKEWGRPAQDITHIVYVSSSEIRLPGGDLYLASQLGLRTDVSRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKDRPYDLVGAALFGDGAAAVIIGTDPLTGQESPFMELNYAVQQFLPDTHNVIDGRLSEEGINFKLGRDLPQKIEDNIEKFCKKLMAKGDIKEFNDLFWAVHPGGPAILNRLENTLKLRSEKLECSRRALMDYGNVSSNTIFYVMEYMREELKIRGEEWGLALAFGPGITFEGILIRSL
MASSLDAIRKAQRAEGPATILAIGTATPSNCVSQADYPDYYFRITKSEHMTELKEKFKRMCDKSMIKKRYMHLNEEILNENPKMCEYMAPSLDARQDIVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDSHLDSLVGQALFGDGAAAVIIGADPDTKVERPLFQLVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGIISKNIEKSLVEAFTPIGISDWNSLFWIAHPGGPAILDQVEIKLGLKEEKLRSTRHVLSEYGNMSSACVLFILDEMRKSSAENGKATTGEGLDWGVLFGFGPGLTVETVVLHSVPVETSH
>Caden.02G117400.1.v1.1
MVTVDEVRKLQRAEGPATVMAIGTATPPNCVDQSTYPDYYFRITNSEHKTELKEKFKRMCDKSMIKKRYMYLTEEILKENPHVCEYMAPSLDARQDMVVVEVPRLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAIIIGADPIPEVEKPLFELVSASQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLAEAFQPLGISDWNSLFWIAHPGGPAILDQVELKLGLKPEKMRATRHVLSEYGNMSSACVLFILDEMRKKSKEDGLKTTGEGLEWGVLFGFGPGLTVETVVLHSVSS
>Caden.02G117700.1.v1.1
MVTVDEVRKLQRAEGPATVMAIGTATPPNCVDQSTYPDYYFRITNSEHKTELKEKFKRMCDKSMIKKRYMYLTEEILKENPHVCEYMAPSLDARQDMVVVEVPRLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAIIIGADPIPEVEKPLFELVSASQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLAEAFQPLGISDWNSLFWIAHPGGPAILDQVELKLGLKPEKMRATRHVLSEYGNMSSACVLFILDEMRKKSKEDGLKTTGEGLEWGVLFGFGPGLTVETVVLHSVSS
>Caden.06G159300.1.v1.1
MADEKSEIKKRNLHLTEEFLKKSSSICAYNVPSLDARQDIKIMETPKLGAEAARKAIEEWGQPKSKITHLIFHASSGVDMPGCYADGTILRIAKDLAENNVAARVLAVCSEMTVDSFRGPLDSDMSCLVGQAIFGDGAAALIIGANHDTLLEERPLFELVSAAQTIVPNSEGALEAHLREVGLTFYLSKDLPTLVSNSIKTCLVEAFSELGISDWNSLFWIVHSGGPAILKEIEAKVRLNKEKLRASWHILREYGNMLGTSVFFILDEMRRKSLEEGKSTTGEGLEWGVLFGFGPGVTVETIVLRSVPIITTSP
>Caden.07G170800.1.v1.1
MGSEGIAQECSKKVANPGTATILALGKAFPHQLVMQDYLVDGYFRDTNCDDPVLKQKLTRLCKTTTVKTRYVVMSEEILKKYPELAIEGLPTVKQRLDICNDAVTQMAVEASQACIKNWGRPISDITHLVYVSSSEARLPGGDLYLARGLGLGPEIQRVMLYFMGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSAKRPYDLVGVALFGDGAGAMIIGSDPVLGNEKPLFELHTAIQEFLPETEKTIDGRLTEEGISFKLARELPQIIEDNIEGFCEKLIKVVGFPEKEYNKMFWAVHPGGPAILNRMEKRLELSPEKLNASRRALMDYGNASSNTIVYVLEYMLEESLKIKRENQGDNEWGLILAFGPGITFEGILARNLTV
>Caden.11G176000.1.v1.1
MSRTNGNGTPNHYSAQTRRIPTPGKATVLALGKAFPSQLVPQECLVEGYIRDTKCVDLSVKEKLERLCKTTTVKTRYTVMSKEILDKYPELATEGSPTIKQRLEIANPAVVEMAMEASLACIKEWGRPAQDITHIVYVSSSEIRLPGGDLYLASQLGLRTDVSRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKDRPYDLVGAALFGDGAAAVIIGTDPLTGQESPFMELNYAVQQFLPDTHNVIDGRLSEEGINFKLGRDLPQKIEDNIEKFCKKLMAKGDIKEFNDLFWAVHPGGPAILNRLENTLKLRSEKLECSRRALMDYGNVSSNTIFYVMEYMREELKIRGEEWGLALAFGPGITFEGILIRSL
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University