Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Carya illinoinensis
Species name
Pecan (Carya illinoinensis) is a species of eudicot in the family Juglandaceae (walnut family).
Species info
Gene sequence info
Carya_illinoinensis.CHS.fa
Download
>rna-XM_043132918.1
MVTVEDVRRAQRAEGPATVMAIGTATPPNCVDQSTYPDYYFRITNSEHKTELKEKFKRMCDKSMIRKRYMYLTEEILKENPNVCAYMAPSLDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSESHLDSLVGQALFGDGAAAIIIGADPIPQVEKPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLAEAFQPLGITDWNSLFWIAHPGGPAILDQVEEKLALKPEKLRSTRHVLSEYGNMSSACVLFILDEMRRKSVEDGLKTTGEGLEWGVLFGFGPGLTVETVVLHSVSA
>rna-XM_043110823.1
MVTVEDVRRAQRAEGPATIMAIGTATPTNCVDQSTYPDYYFRITNSEHKTELKEKFKRMCEKSMIKKRYMHLTEEILKENPNVCAYMASSLDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDAHLDSLVGQALFGDGAAALIVGADPVPGVEKPLFELVSANQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFQPLGITDWNSLFWIAHPGGPAILDQVESKLELKPEKLRATRHVLSEYGNMSSACVLFILDEMRKKSAEDRLKTTGEGLEWGVLFGFGPGLTVETVVLHSVSA
>rna-XM_043113352.1
MASVEEFLKAQRSEGPATVLAIGTANPSNCISQTDFPDYYFRITKSEHLTELKKKFKRMCDKSMIKKRYMHLTEDILKENPGMCEFMAPSYDARQDIAVVELPKLAKEAALKAIKEWGQHKSKITHLVFCTTTGTADMPGADYQLIKLLGLKSSVKRVMMYQQGCFGGGTVLRLAKDLAENNRGARVLAVCAEIVAISFRGPSEAHFDSLVGQSLFGDGAAAVIIGADPDTCVERPLFQLASAAQTILPDSDGAVQGHLREVGLTFHALKDLPKIVSRNIEQSLVEAFTPFGVSDWNSIFWIVHPGGPAILDQVEAKLNLQEEKLRASRHILSEYGNMSTACVLFILDEMRKSSVEDGKATTGGGLEWGVLFGFGPGLTVETVVLRSVPVETIH
>rna-XM_043127922.1
MGSEDVARGGSTKWANPGKATILALGKAFPHQLVMQDYLVDGYFRDTNCDDPVLKQKLTRLCKTTTVQTRYVVMSEEILKKYPELAVEGLPTVKQRLDICNDAVTRMAIEASQACLKNWGRPISDITHLVYVSSSEARLPGGDLYLAKGLGLSPDTQRVMLYFVGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGYKPPSAERPYDLVGVALFGDGAGAMLIGSDPVLGYEKPLFELHTAIQQFLPDTEKTIDGRLTEEGISFKLARELPQIIEDNIEGFCKKLIKVVGFPDQEYNKMFWAVHPGGPAILNRMEKRLELLPEKLNASRRALMDYGNASSNTIVYVLEYMIEENLKIKKENQGDNEWGLILAFGPGISFEGILARNLTD
>rna-XM_043130600.1
MASMEEIRKAQRAQGPANILAIGTATPSNCVSQADYPDFYFRITKSEHMTELKEKFKRMCDKSMIKKRYMYLTEEILKENPNMCAYMAPSLDARQDIVVLEVPKLGKEAASKAIKEWGQPKSRITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRYMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDSHLDSLVGQALFGDGAAALIVGADPDTSIERPLYQVVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFTPIGISDWNSIFWIAHPGGPAILDQVEAKLGLKEEKMRATRQVLSDYGNMSSACVLFILDEMRKKSAKEGKATTGEGLEWGVLFGFGPGLTVETIVLHSVNI
>rna-XM_043100405.1
MATISSSRSRLFALVRKPFSMSSSQHRSTPRCYCSQQSITSIEDDKNGDKELDRFVKSKASAKTKRAKAMARLINSKPWSSELEPSLSSLSPSLSKTAVLQTLRLIRTPSKAFQFFNWVHEMGFSHTDQSYFMMLEILGRDRKLNVARNLLFSMEKRSNGMVKLEDRFFNSLIRNYGRAGLFQESIKLFTTMKSLGVSPSVVTFNSILTILLRRGRTNMAKDMYDEMLRTYGVTPDTYTFNILIRGFCKNSMVDEGFQFFKLMSRFSCEPDVITYNTLVDGLCRVGKVRIAHNVVKGMSKKSMDLNPNVVTYTALIRGYCMKQEIDEALVLLEEMNSQGLKPNIITYNTLIKGLCEAQNLEKIKEILEGMTEVGGFTPDTCTFNTIIHAHCSAGNLDEALNVFEKMSELQVQPDSATYSVLIRSLCQIGDYSRAEKLFGELSEKKILLCDVGCKPLVAAYNPMFEYLCGNGKTNKAEIVFRQLMKRGRQDPPSYKTLIMGHCREGTYEAGYELLVWMLRRDFVPDFEIYESLIGGFLQKGRPLLAQQTLEKMLKSSHLPKTSTFHSILAELIEKGCARESSSFIMLMLERKIRQNINLSTDCIRLLLDRGLRDKAFQIVGMIYENGYSVKIEELVGFLCQSRKLLEARDMFLFSLDKHQNIDTNTCNILIVGLCKMKKLSEAFGLYYELVEKGVHQQLTCLYDLKTALDAGGRSDQAEFVSKRMSGQGHLDKPGSKSRPKQLCQLSLSSHQTQIYLLSQQLLKMSRTYGNGAVNEYPAQIRRIPTPGKATVLALGKAFPSQLIPQECLVEGYIRDTKCEDLSIKEKLERLCKTTTVKTRYTVMSKEILDKYPELATEGSPTIKQKLEIANPAVLEMAMEASLACIKEWGRPAEDITHIVYVSSSEIRLPGGDLYLASQLGLRNDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKERPYDLVGAALFGDGAAAVIIGSNPLKGQESPFMELNYAVQQFLPETHTVIDGKLSEEGINFRLGRDLPQKIEDNIEEFCKKLMAKANLINFNDLFWAVHPGGPAILNRLESTLNLTSEKLKCSRRALMDYGNVSSNTIFYVIDYMREELKRGTEEWGLALAFGPGITFEGILIRCL
>rna-XM_043105654.1
MASVEEMREAPRARGLATILAIGTANPKNCIHQKDYPDFYFRVTESEHMTELKDKFKRICDRTTIRKRYCHLTEEILKANSNMCKYKAPSLDARQNMLISEVPKLGKEAALKAIEEWGQSISKITHLVFCSSSSIDMPGADFQLTKLLGLNLSINRYLISHQACYAGGTGLRIAKDLAENNAGARVLVVCSDIMTVLFHAPCETHIDILIGQALFTDGAAAVIIGANPDTSIEHPLFELVSARQSIIPDSESGIRGTVREMGLTYYLSEKVPKSVGDYINNCLVETFNPIGISDWNSLFYVVHPGGPAILNRIQEKLDLNEEKLRASRHVLSEYGNMTGPCVLFVLDEMRKKSAEEGNATTGEGLEWGILLGLGPGLTVETLVLHSIPIN
>rna-XM_043105709.1
MASVEEMRKAPRARGLATILAIGTANPKNCIHQKDYPDFYFRVTGSEHMTELKDKFKRICDRTTIRKRYCHLTEEILKANSNMCKYKAPSLDARQNMLISEVPKLGTEAALKAIEEWGQPISKITHLVFCSSSSIDMPGADFQLTKLLGLNLSINRYLISHQACYAGGTGLRIAKDLAENNAGARVLVVCSDIMTVLFHAPCETHIDILIGQALFTDGAAAVIIGANPDTSIEHPLFELVSARQSIIPDSESGIRGTVREMGLTNYLSEKVPKSVGDYINNCLVETFSPIGLSDWNSLFYVVHPGGPAILNRIQEKLDLNEEKLRASRHVLSEYGNMTGPCVLLVLDEVRKKSAEEGNATTGEGLEWGVLLGLGPGLTVETLVLHSIPIN
MVTVEDVRRAQRAEGPATVMAIGTATPPNCVDQSTYPDYYFRITNSEHKTELKEKFKRMCDKSMIRKRYMYLTEEILKENPNVCAYMAPSLDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSESHLDSLVGQALFGDGAAAIIIGADPIPQVEKPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLAEAFQPLGITDWNSLFWIAHPGGPAILDQVEEKLALKPEKLRSTRHVLSEYGNMSSACVLFILDEMRRKSVEDGLKTTGEGLEWGVLFGFGPGLTVETVVLHSVSA
>rna-XM_043110823.1
MVTVEDVRRAQRAEGPATIMAIGTATPTNCVDQSTYPDYYFRITNSEHKTELKEKFKRMCEKSMIKKRYMHLTEEILKENPNVCAYMASSLDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDAHLDSLVGQALFGDGAAALIVGADPVPGVEKPLFELVSANQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFQPLGITDWNSLFWIAHPGGPAILDQVESKLELKPEKLRATRHVLSEYGNMSSACVLFILDEMRKKSAEDRLKTTGEGLEWGVLFGFGPGLTVETVVLHSVSA
>rna-XM_043113352.1
MASVEEFLKAQRSEGPATVLAIGTANPSNCISQTDFPDYYFRITKSEHLTELKKKFKRMCDKSMIKKRYMHLTEDILKENPGMCEFMAPSYDARQDIAVVELPKLAKEAALKAIKEWGQHKSKITHLVFCTTTGTADMPGADYQLIKLLGLKSSVKRVMMYQQGCFGGGTVLRLAKDLAENNRGARVLAVCAEIVAISFRGPSEAHFDSLVGQSLFGDGAAAVIIGADPDTCVERPLFQLASAAQTILPDSDGAVQGHLREVGLTFHALKDLPKIVSRNIEQSLVEAFTPFGVSDWNSIFWIVHPGGPAILDQVEAKLNLQEEKLRASRHILSEYGNMSTACVLFILDEMRKSSVEDGKATTGGGLEWGVLFGFGPGLTVETVVLRSVPVETIH
>rna-XM_043127922.1
MGSEDVARGGSTKWANPGKATILALGKAFPHQLVMQDYLVDGYFRDTNCDDPVLKQKLTRLCKTTTVQTRYVVMSEEILKKYPELAVEGLPTVKQRLDICNDAVTRMAIEASQACLKNWGRPISDITHLVYVSSSEARLPGGDLYLAKGLGLSPDTQRVMLYFVGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGYKPPSAERPYDLVGVALFGDGAGAMLIGSDPVLGYEKPLFELHTAIQQFLPDTEKTIDGRLTEEGISFKLARELPQIIEDNIEGFCKKLIKVVGFPDQEYNKMFWAVHPGGPAILNRMEKRLELLPEKLNASRRALMDYGNASSNTIVYVLEYMIEENLKIKKENQGDNEWGLILAFGPGISFEGILARNLTD
>rna-XM_043130600.1
MASMEEIRKAQRAQGPANILAIGTATPSNCVSQADYPDFYFRITKSEHMTELKEKFKRMCDKSMIKKRYMYLTEEILKENPNMCAYMAPSLDARQDIVVLEVPKLGKEAASKAIKEWGQPKSRITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRYMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDSHLDSLVGQALFGDGAAALIVGADPDTSIERPLYQVVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFTPIGISDWNSIFWIAHPGGPAILDQVEAKLGLKEEKMRATRQVLSDYGNMSSACVLFILDEMRKKSAKEGKATTGEGLEWGVLFGFGPGLTVETIVLHSVNI
>rna-XM_043100405.1
MATISSSRSRLFALVRKPFSMSSSQHRSTPRCYCSQQSITSIEDDKNGDKELDRFVKSKASAKTKRAKAMARLINSKPWSSELEPSLSSLSPSLSKTAVLQTLRLIRTPSKAFQFFNWVHEMGFSHTDQSYFMMLEILGRDRKLNVARNLLFSMEKRSNGMVKLEDRFFNSLIRNYGRAGLFQESIKLFTTMKSLGVSPSVVTFNSILTILLRRGRTNMAKDMYDEMLRTYGVTPDTYTFNILIRGFCKNSMVDEGFQFFKLMSRFSCEPDVITYNTLVDGLCRVGKVRIAHNVVKGMSKKSMDLNPNVVTYTALIRGYCMKQEIDEALVLLEEMNSQGLKPNIITYNTLIKGLCEAQNLEKIKEILEGMTEVGGFTPDTCTFNTIIHAHCSAGNLDEALNVFEKMSELQVQPDSATYSVLIRSLCQIGDYSRAEKLFGELSEKKILLCDVGCKPLVAAYNPMFEYLCGNGKTNKAEIVFRQLMKRGRQDPPSYKTLIMGHCREGTYEAGYELLVWMLRRDFVPDFEIYESLIGGFLQKGRPLLAQQTLEKMLKSSHLPKTSTFHSILAELIEKGCARESSSFIMLMLERKIRQNINLSTDCIRLLLDRGLRDKAFQIVGMIYENGYSVKIEELVGFLCQSRKLLEARDMFLFSLDKHQNIDTNTCNILIVGLCKMKKLSEAFGLYYELVEKGVHQQLTCLYDLKTALDAGGRSDQAEFVSKRMSGQGHLDKPGSKSRPKQLCQLSLSSHQTQIYLLSQQLLKMSRTYGNGAVNEYPAQIRRIPTPGKATVLALGKAFPSQLIPQECLVEGYIRDTKCEDLSIKEKLERLCKTTTVKTRYTVMSKEILDKYPELATEGSPTIKQKLEIANPAVLEMAMEASLACIKEWGRPAEDITHIVYVSSSEIRLPGGDLYLASQLGLRNDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKERPYDLVGAALFGDGAAAVIIGSNPLKGQESPFMELNYAVQQFLPETHTVIDGKLSEEGINFRLGRDLPQKIEDNIEEFCKKLMAKANLINFNDLFWAVHPGGPAILNRLESTLNLTSEKLKCSRRALMDYGNVSSNTIFYVIDYMREELKRGTEEWGLALAFGPGITFEGILIRCL
>rna-XM_043105654.1
MASVEEMREAPRARGLATILAIGTANPKNCIHQKDYPDFYFRVTESEHMTELKDKFKRICDRTTIRKRYCHLTEEILKANSNMCKYKAPSLDARQNMLISEVPKLGKEAALKAIEEWGQSISKITHLVFCSSSSIDMPGADFQLTKLLGLNLSINRYLISHQACYAGGTGLRIAKDLAENNAGARVLVVCSDIMTVLFHAPCETHIDILIGQALFTDGAAAVIIGANPDTSIEHPLFELVSARQSIIPDSESGIRGTVREMGLTYYLSEKVPKSVGDYINNCLVETFNPIGISDWNSLFYVVHPGGPAILNRIQEKLDLNEEKLRASRHVLSEYGNMTGPCVLFVLDEMRKKSAEEGNATTGEGLEWGILLGLGPGLTVETLVLHSIPIN
>rna-XM_043105709.1
MASVEEMRKAPRARGLATILAIGTANPKNCIHQKDYPDFYFRVTGSEHMTELKDKFKRICDRTTIRKRYCHLTEEILKANSNMCKYKAPSLDARQNMLISEVPKLGTEAALKAIEEWGQPISKITHLVFCSSSSIDMPGADFQLTKLLGLNLSINRYLISHQACYAGGTGLRIAKDLAENNAGARVLVVCSDIMTVLFHAPCETHIDILIGQALFTDGAAAVIIGANPDTSIEHPLFELVSARQSIIPDSESGIRGTVREMGLTNYLSEKVPKSVGDYINNCLVETFSPIGLSDWNSLFYVVHPGGPAILNRIQEKLDLNEEKLRASRHVLSEYGNMTGPCVLLVLDEVRKKSAEEGNATTGEGLEWGVLLGLGPGLTVETLVLHSIPIN
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University