Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Carthamus tinctorius
Species name
Safflower (Carthamus tinctorius) is a species of eudicot in the family Asteraceae (daisy family).
Species info
Gene sequence info
Carthamus_tinctorius.COMT.fa
Download
>CtAH01T0092200.1
FYLERFKLKDAVVEGGVPFAKVHETSAFEYPELDTGYNATFNNAMVNHSAIVIKEILKCYHGFDNVKHLVDVGGGVGVTLNMIISKHPTINAINFDLPHVIQHAPFYLGIKHVGGDMFLDVPQGDAIFMKWIPHDWSDDHCVKLLKNCYKVLPDDGKVIVVEAIRPLFSDTSTSTKAIANMDAIMMANFLGGKERTEDEFFALAKGAGFTGIKKACQLVTSISLPMVLENAMKLGVLEAIAEAGPDAKLSAREIAYGLSILNRDAPDMLDRMLRLLASYSIVTCTQQDREMKLCQVYGLAPVAKYLIRNEDGMSLGPLLELNLDKVFKLKDAVVEGGVPFAKVHETSAFEYPELDTGYNATFNNAMVNHSAIVIKEILKCYHGFDNVKHLVDVGGGVGVTLNMIISKHPTINAINFDLPHVIQHAPFYLGIKHVGGDMFLDVPQGDAIFMKWILHDWSDDHCVKLLKNCYKVLPDYGKVIVVEAIRPLFSDTSTSTKAIANMDAIMMANFLGGKERTEDEFLALAKGVGFTGIKKACQVRSFSLALV
>CtAH06T0148700.1
MRISALFIQRMEERIGILQAQDPNLNDFFNEAMASLNSIVDVGGGTGTFAKAIAEAFPTHNCIIFDLPHVVNGMEGRNNFSYVRGDVFEAIPKADAMLKRCKEAIPQKENGGKLVIIDMVMKNHDGGDDSLRTQLFFDMLLILKT
>CtAH07T0161000.1
MGSSSPYVNVPVEAKEDESFLFAMQLATASVLPMALKTAIELDLLETIAKAGPGASLSSSQLAAQLPVVNNPEAPVMLDRICSLLASHSVLTCSLKDLDDGGVERLYGLAPVCKFLIKNQDGVSMAPLLLMNQDKDAVLDGGIPFNKAYGMSAFEYHGKDPRFNKVFNSGMFNHSTMTMKKIVDLYDGFNGLTTLVDVGGGTGASLNMIIAKHTSLKGINFDLPHVIEDATTYPGIEHVGGDMFESVPKGDAIFMKWILHDWSDAHCLKFLKNCYEALPANGKVIVAECILPEAPDSTTATQNVVHIDVIMLAHNPGGKERTEKEFEALAKGAGFKGFHKAACALNTWENMGSFSVQCNLTPEKSPKRQ
>CtAH07T0161100.1
MGSSSPYVNVPVEAKEDEKSFLFAVQLATATVLQMALKAAIELDLLETIAKAGSGASLSSSQLAAQLPVVNNPEAPVMLDRICSLLASHSVLTCSLKDLDDGGVERLYGLAPVCKFLIKNQDGVSMAPLLLVNQDKVFMESWYHLKDAVLDGGIPFNKAYGMSAFEYHGKDPRFNKVFNSAMFNNSTMTMKKIVELYDGFNGLTTLVDVGGGTSASLNMIIAKHTSLKGINFDLPHVIEDATTYHGIEHVGGDMFESVPKGDAIFMKSVLHDWSDAHCLKFLKNCYEALPSNGKVIVAEYILPEAADLTTANQNVVHMDVIMLAYTRGGKERTEKEFEALAKGAGFKSFHKAACAHNTWVMEFCK
>CtAH07T0172400.1
MANLGIDCCGIDLVHGANAFEYPSLDARFNEVFNNAMLNHTTLVIKEILKCYLGFAKLKHLVDVGGIKHVGGDMFHDVPQGDAIFMKWILHDWSDDHCIKLLKNCYNALPDDGKVIVVEAILPVLSDTSTSVKATTHMDAIMMTQNPGGKERSEDEFLTLAKGAGFTRIKKECNVCNFWVMELYK
>CtAH07T0173000.1
MGSNDDFAYALQLVTSISLPMVLENAMKLRVLEAISEAGPGARLSAHEIANALSIPNQDAPGMLDRMLRLLASYSIVTCTQQGSEMKPIRVYGLAPVAKYLIQNEDGVSLRALMELILDKVFIKKRAKLQDSVVEGGVPFEKVYGQKTFQYPELDTRYNEVFNNAMVHHSTLVIKELLKCYNGFGNVKHLVDVGGGIGVSLNMIISRYPTINGINFDLPHVIQHAPLYPGIKHVGGDMFFDVPQGDAIFLKWILHDWSDDHCTKLLKNCYKALPTEGKVIVVDAILPFLSDTSTSARANANIDAIVMTHYSGGKERTEDEFLALAKGAGFNGIKKECQVCNMWVMELYK
>CtAH08T0001500.1
MAHLEEEEAFLFAMQLASASVLPMVLKSAIDLDLLEIIAKAGPGAHVSPAYLAAQLPKADNPEAAVMLDRICRLLATYSVLTCTLKKLDHGDGDVERLYGLAPVCKFLVKNEDGVSNAPLLLMNQDKILMESWYHLKDAVLDGGIPFNKAYGMSAFEYHGKDERFNKVFNSGMFNHSTMTMKKILDVYPGFNGVKTLVDVGGGTGASLSMILSKHPSIKGINFDLPHVIQDATNYPGIEHVGGDMFESVPKGDAIFMKWICHDWSDAHCLKFLKNCYKALPENGKVIVAECILPETPDSSLATKNVVHIDVIMLAHNPGGKERTEKEFQALAKAAGFKGFHKPCSALNTWLMEFTK
>CtAH08T0272700.1
MENRHGEAPPCTAATNAGSRLAIMELANMISVPMSLNAVVRLNVADAIWQNGENTPLSASEILSRIFPSGAGDPENLQRILRMLTSYGVFNEHIASGDASKRRYSLTDVGKALVTDENGLSYGAYVLQHHQPELMKAWAVVHEAVVDSSTEPFVKANGGETAYGIYGKKPEMNELMLRAMSGVSVPFMKAVLDGYDGFDGVERLVDVGGSAGDCLRMILEKHSRIKEGVNFDLPEVVAKAPQIDGVTHVGGDMFKFIPKGDAIFMKWVLTTWTDDEVKAIMINCFKSIPVGGKLIACEPVLPKQTDDSHRTRALLEGDIFVMTIYRAKGKHRTEDEYRQLGKSVGFLSFRAIYIDQFYTLLEFQK
>CtAH09T0250400.1
MSNEEEGLQKVMQINSGIVLPMVVKTAMELDLFEIMAKTPGARFSSYDLASKLPSQTPQTRHLLERILRFLATQSILELSIETDEHGNSKNLYSMTPVSNHFVLKQDGTSLVIDGGIPFDKAHGVNAFEYPAKDNRFNQVFNKAMYDNTRIVMKLILEKYKGFEGAEELVDVGGGLGVEHVGGDMFESVPKGDVIFMKWILHDWGDDYCIKLLKNCWAALPEYGKVVVVEVVMPDPEHQPISPADYASSQAAVGSDMIMLIANPGGRERTEKEFDTMAKEAGFSSTRIIQGKTKKI
>CtAH09T0250500.1
MGYPRDGVCPWGVMKYQGTGCALGNEEEFKEQARAKRKRLSSLDGQLLGYTLGVEHTGGDMFESVPKGDVIFMKWILHDWGDDYCIELLKNCWAALPEYGKVVVK
>CtAH09T0250200.1
MSNEEEGLQKMREIRSAIVLPMIIKTAIELDLFEIMAKTPGARFSSCDLASNLPSQTPQTPHLLERILRFLATQSILESTTEIDEHGNSKSLYSMTPVSNHFVRDQDGTSSGSLLLLVYDKVHHLKDAVIDGGIPFNKAHGVNAFEYPAKDNRFNQVFNKAMYDNTRIVMKSILEKYKGFEGVKELVDVGGGLGATLQLIIDKYPNNCWEALPEYGKVVVVERIMPDPEHQPISADDYVSSQAVVSSDMTMLIANPGGKERTKKEFDALAKEGAFNSTKI
FYLERFKLKDAVVEGGVPFAKVHETSAFEYPELDTGYNATFNNAMVNHSAIVIKEILKCYHGFDNVKHLVDVGGGVGVTLNMIISKHPTINAINFDLPHVIQHAPFYLGIKHVGGDMFLDVPQGDAIFMKWIPHDWSDDHCVKLLKNCYKVLPDDGKVIVVEAIRPLFSDTSTSTKAIANMDAIMMANFLGGKERTEDEFFALAKGAGFTGIKKACQLVTSISLPMVLENAMKLGVLEAIAEAGPDAKLSAREIAYGLSILNRDAPDMLDRMLRLLASYSIVTCTQQDREMKLCQVYGLAPVAKYLIRNEDGMSLGPLLELNLDKVFKLKDAVVEGGVPFAKVHETSAFEYPELDTGYNATFNNAMVNHSAIVIKEILKCYHGFDNVKHLVDVGGGVGVTLNMIISKHPTINAINFDLPHVIQHAPFYLGIKHVGGDMFLDVPQGDAIFMKWILHDWSDDHCVKLLKNCYKVLPDYGKVIVVEAIRPLFSDTSTSTKAIANMDAIMMANFLGGKERTEDEFLALAKGVGFTGIKKACQVRSFSLALV
>CtAH06T0148700.1
MRISALFIQRMEERIGILQAQDPNLNDFFNEAMASLNSIVDVGGGTGTFAKAIAEAFPTHNCIIFDLPHVVNGMEGRNNFSYVRGDVFEAIPKADAMLKRCKEAIPQKENGGKLVIIDMVMKNHDGGDDSLRTQLFFDMLLILKT
>CtAH07T0161000.1
MGSSSPYVNVPVEAKEDESFLFAMQLATASVLPMALKTAIELDLLETIAKAGPGASLSSSQLAAQLPVVNNPEAPVMLDRICSLLASHSVLTCSLKDLDDGGVERLYGLAPVCKFLIKNQDGVSMAPLLLMNQDKDAVLDGGIPFNKAYGMSAFEYHGKDPRFNKVFNSGMFNHSTMTMKKIVDLYDGFNGLTTLVDVGGGTGASLNMIIAKHTSLKGINFDLPHVIEDATTYPGIEHVGGDMFESVPKGDAIFMKWILHDWSDAHCLKFLKNCYEALPANGKVIVAECILPEAPDSTTATQNVVHIDVIMLAHNPGGKERTEKEFEALAKGAGFKGFHKAACALNTWENMGSFSVQCNLTPEKSPKRQ
>CtAH07T0161100.1
MGSSSPYVNVPVEAKEDEKSFLFAVQLATATVLQMALKAAIELDLLETIAKAGSGASLSSSQLAAQLPVVNNPEAPVMLDRICSLLASHSVLTCSLKDLDDGGVERLYGLAPVCKFLIKNQDGVSMAPLLLVNQDKVFMESWYHLKDAVLDGGIPFNKAYGMSAFEYHGKDPRFNKVFNSAMFNNSTMTMKKIVELYDGFNGLTTLVDVGGGTSASLNMIIAKHTSLKGINFDLPHVIEDATTYHGIEHVGGDMFESVPKGDAIFMKSVLHDWSDAHCLKFLKNCYEALPSNGKVIVAEYILPEAADLTTANQNVVHMDVIMLAYTRGGKERTEKEFEALAKGAGFKSFHKAACAHNTWVMEFCK
>CtAH07T0172400.1
MANLGIDCCGIDLVHGANAFEYPSLDARFNEVFNNAMLNHTTLVIKEILKCYLGFAKLKHLVDVGGIKHVGGDMFHDVPQGDAIFMKWILHDWSDDHCIKLLKNCYNALPDDGKVIVVEAILPVLSDTSTSVKATTHMDAIMMTQNPGGKERSEDEFLTLAKGAGFTRIKKECNVCNFWVMELYK
>CtAH07T0173000.1
MGSNDDFAYALQLVTSISLPMVLENAMKLRVLEAISEAGPGARLSAHEIANALSIPNQDAPGMLDRMLRLLASYSIVTCTQQGSEMKPIRVYGLAPVAKYLIQNEDGVSLRALMELILDKVFIKKRAKLQDSVVEGGVPFEKVYGQKTFQYPELDTRYNEVFNNAMVHHSTLVIKELLKCYNGFGNVKHLVDVGGGIGVSLNMIISRYPTINGINFDLPHVIQHAPLYPGIKHVGGDMFFDVPQGDAIFLKWILHDWSDDHCTKLLKNCYKALPTEGKVIVVDAILPFLSDTSTSARANANIDAIVMTHYSGGKERTEDEFLALAKGAGFNGIKKECQVCNMWVMELYK
>CtAH08T0001500.1
MAHLEEEEAFLFAMQLASASVLPMVLKSAIDLDLLEIIAKAGPGAHVSPAYLAAQLPKADNPEAAVMLDRICRLLATYSVLTCTLKKLDHGDGDVERLYGLAPVCKFLVKNEDGVSNAPLLLMNQDKILMESWYHLKDAVLDGGIPFNKAYGMSAFEYHGKDERFNKVFNSGMFNHSTMTMKKILDVYPGFNGVKTLVDVGGGTGASLSMILSKHPSIKGINFDLPHVIQDATNYPGIEHVGGDMFESVPKGDAIFMKWICHDWSDAHCLKFLKNCYKALPENGKVIVAECILPETPDSSLATKNVVHIDVIMLAHNPGGKERTEKEFQALAKAAGFKGFHKPCSALNTWLMEFTK
>CtAH08T0272700.1
MENRHGEAPPCTAATNAGSRLAIMELANMISVPMSLNAVVRLNVADAIWQNGENTPLSASEILSRIFPSGAGDPENLQRILRMLTSYGVFNEHIASGDASKRRYSLTDVGKALVTDENGLSYGAYVLQHHQPELMKAWAVVHEAVVDSSTEPFVKANGGETAYGIYGKKPEMNELMLRAMSGVSVPFMKAVLDGYDGFDGVERLVDVGGSAGDCLRMILEKHSRIKEGVNFDLPEVVAKAPQIDGVTHVGGDMFKFIPKGDAIFMKWVLTTWTDDEVKAIMINCFKSIPVGGKLIACEPVLPKQTDDSHRTRALLEGDIFVMTIYRAKGKHRTEDEYRQLGKSVGFLSFRAIYIDQFYTLLEFQK
>CtAH09T0250400.1
MSNEEEGLQKVMQINSGIVLPMVVKTAMELDLFEIMAKTPGARFSSYDLASKLPSQTPQTRHLLERILRFLATQSILELSIETDEHGNSKNLYSMTPVSNHFVLKQDGTSLVIDGGIPFDKAHGVNAFEYPAKDNRFNQVFNKAMYDNTRIVMKLILEKYKGFEGAEELVDVGGGLGVEHVGGDMFESVPKGDVIFMKWILHDWGDDYCIKLLKNCWAALPEYGKVVVVEVVMPDPEHQPISPADYASSQAAVGSDMIMLIANPGGRERTEKEFDTMAKEAGFSSTRIIQGKTKKI
>CtAH09T0250500.1
MGYPRDGVCPWGVMKYQGTGCALGNEEEFKEQARAKRKRLSSLDGQLLGYTLGVEHTGGDMFESVPKGDVIFMKWILHDWGDDYCIELLKNCWAALPEYGKVVVK
>CtAH09T0250200.1
MSNEEEGLQKMREIRSAIVLPMIIKTAIELDLFEIMAKTPGARFSSCDLASNLPSQTPQTPHLLERILRFLATQSILESTTEIDEHGNSKSLYSMTPVSNHFVRDQDGTSSGSLLLLVYDKVHHLKDAVIDGGIPFNKAHGVNAFEYPAKDNRFNQVFNKAMYDNTRIVMKSILEKYKGFEGVKELVDVGGGLGATLQLIIDKYPNNCWEALPEYGKVVVVERIMPDPEHQPISADDYVSSQAVVSSDMTMLIANPGGKERTKKEFDALAKEGAFNSTKI
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University