Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Carthamus tinctorius
Species name
Safflower (Carthamus tinctorius) is a species of eudicot in the family Asteraceae (daisy family).
Species info
Gene sequence info
Carthamus_tinctorius.HIDH.fa
Download
>CtAH10T0048200.1
MTSEDEIIKELPGIIRLFKDGRFQKLHVPVLVPAGIDPTSGVDSRDVVFSPENNVSARLYLPKTTPPNRKLPLVIFFHGGGFIVESAASSTYHNFLNLVAAESSAVVVSVDYRLAPEFPLPAAYEDSWEAIKWVAGHGNGDGPDPWLNEHADLQNVFLAGDSAGGGAAAPSGSYVAPPLGSGPVAGIGVRGAILLHPYFWGIERIGTESDSLKPEMIATLDGLWSMADPESSGPDDPLINPGMDPRIAGMGCSKILVCVGGNDFMRERNWYYKQVIEESGWKGELEVVEDKGEGHVFFLFYPSSPNACALRTRICTFINN
>CtAH10T0263800.1
MGGHVVDDCRGVLKVFGDGSIWRSTEPSFQVPVVDDGSVLWKDVVFDQPNNLSLRLYKPAPIGPDRPDKLPVFYYIHGGGFCIGSRTWPNCQNYCFKLARDLGAVVVAPDYRLAPESRLPLANEDGFSAVKWLRDQATGSEPDPWLVESADFGRVFVCGDSAGGNIAHNVAVRLGAGSKGLDPVRVRGYVLLAPFFGGTVLTRSEAEGPDDAFLNWELIDRFWRLSIPVGDTMDHPLVNPFGPVSVDLEPVELDPILVVCGGCDLLKDRAKDYAERLKSWGKKVTYEEFEGQQHGNGMTYISSFIQSKG
>CtAH11T0185300.1
MGSLPHVVEDCYGLVQIFSDGSIHRHEKIDFSAFPVKDDGSVVWKDYCYDLLHGLRLRFYKPKSSTTAAKLPAIFYLRGGGFCLGSFAWPNIHNSCLRLSSALQAVVVAPDYQLAPEHRLPAAMDDSLAALKWLQDLGRNPKGGGDGDVVDCVDFDRFFVAGDSSGGNIAHHLAVRLGPGSPELAPIKVRGYVMMAPFFGGKERTRSEAEGSPETFLDIDILDMFWRMSLPVGNTADHPYANPFGPQSPSLEPIKLDPILLIAGGDEIMKDRVELYAKRLKELGKMAQYVEFKGKQHGFFTNEPYSNVSDSFLKLIKDFMFEHSS
>CtAH03T0075000.1
MTSIFGSGKIITSDQYLFQINGFLRVHTDGRCERLVGIKTVPSGIDPSTGVHSKDVVISPETNLSVRLYFPKTASPNPKQKLPVVIYFHGGGFAVESARSPTYHPTLNLLAAKSGVIVVSVDYRLAPEHPLPIGYNDSWEAIKWVATHGSKEPWLDDDVADFQKVFLAGDSAGANIAHNMAIRFGSDPIGSIKLNGIILLHPFFGGEDPIGSECGKHKQLKAYTDQFWKLANPDSGSGLDDPWFNPEKDPKVGGLGCGKILVCVAEKDSLRDRGINYRDLMGRSGWNGELEVMETKGEDHVFFLFNPSCENACSLHNKVCSFINQTHHQQSRC
>CtAH03T0074900.1
MNQENIKLQINHHRYQLSSRKKDEVKQRFAPIHRPMTTHSNNHPAMESTQHEILHDFHPILRVYKDGHVHKMTTTPILPPSDDPQTTVRSKDVVISAHPKVAARLYLPKTTTTKLPLLIYIHGGAFAIESAFSTLYHNHLNTLTAAANVAAVSIEYRLAPEHPIPACYDDCWETLKWVLDTQDPWIRNHADLSRVFLAGDSAGANIAHNVMVRFSENGAGSGLKQGRIYVEPRFATGLKIMGMALIHPFFSFDEEDKLWMYLCPGTSGLDDPRMNPAADPGLLAKMVCEKVVVCTAGKDHLRDRGWSYYEALKKSGWGGQLQIMESEDEEHCFHLFNPTCQRAQALNVAGPISGHTTSGIHLRLRHPPSSPPSDSGPPLPELDQRPRQSRRRRRSDWG
>CtAH05T0192700.2
MGSDQEQDVAFELLPFLRLHKDGTVERLYHPTLCPPSPVAATTTTTTTGGVCSKDVIISPNVSARLYLPNNNLPLLSSGGKKLLPILVYFHGGGFCIESAFSTLCHRYMTTLASLANALIVSVDYRLAPENPLPAAYQDSWAALQWVASHANKEHNQRDEPWLVQHADFDRLYIGGDSAGANISHHMAMRAGTENLHGGVKILGAFLSYPYFLGSNPLGSESVTGHEMSLLHKTWMIVYPGAPDGIDNPLINPFAKTAPCLMGLGCRRLIVCVASEDELKDRGVHYHDAVKESGWQGEISLFEAQGEGHCFHIFNPETKNAKEMFKRLAGFLQEC
>CtAH05T0096900.1
MSPADEIIKEIPGLVRVFKDGRIEKFRDPVLVPAGIDPSTGVISKDVVFSPENNNFARIYIPKTTVTQARKLPLLIYFHGGGFVIESAASSTYQGFLNLVAAESGAVVVSADYRLAPEFPLPAAYEDAWAAIGWVAGHGDGDGPDPWLNQYADLQNVFLAGDSAGGNIAHHMAIRAGSDPLPGLRIRGNILLHPYFWGKERVGTESEFIEESVVAILDDLWGLVHPGGVGPEDPFINPGMDPNVAGMGCPKILVCVGGKDVLKERGWWYKQVIEKSGWEGELEVVEDKGEDHVFFLMNPCAPNACTLRTRICTFINN
>CtAH05T0057100.1
MYTIHHFSNFTNLFFTLMASNKELSFELPGVIRVYNDGSVERLMISPYVSPSLQDPINGGISSKDIAISPHVSVRLYLPKSAVPTSSQKLPVFVYIHGGGFVVGSAFTLFEHNYLNTIVSHINALVISVEYRLAPEHLLPTAYEDCWTALQWVASHATSNGKNSENQEPWLVEFGDFERLYIGGDSAGANIVHNLAMRAGRESLNGDVKILGAFLGCPYFWGSSYGVESLPCGCWMMAYPEAEGGIDSPMINPFVGDGDGRGFAAEYGVRKLLVVATEKDEFRDIDVEYFESVKGSEWGGEVELLEIEGESHCFYAMDTTSEKAKVVMERLASFVELSFEIPNLIRVYKDGSVERLMISPYVSPSLQDPVNGISTKDIAISPHVSVRLYLPKSAAPTSSRKLPVFVYVHGGGFVVGSAFTLLEHSYLNAIVSHTNALVISVEYRLAPEHLLPAAYEDCWTALQWVASHATNHGENSENDQEPWLVEFGDFERLYIGGDSAGANIVHNLALQAGRESLNGGVKILGAFLGCPYFWSSSYGVESLAYGCWMMAYPQAEGGIDNPMINPFVGGGGGRGFAAEYGVRKLLVVAAEQDMLRDINVKYFEGVKGSDWDGEVEFLEIEGENHCFYAMDTTSEKAK
>CtAH05T0096700.1
MSSEDEIIKEVPGIIRLFKDGRFQKLHVPVMVPAGVDPTSGVDSKDVMFSPQYNVSARVYIPKTTPPNRKLPLVIYFHGGGFIIESAASSTYHNFLNLVVAESEAVLVSVDYRLVPEFPLSAAYEDSWEAIKWVAEHGNGDGPDPWLNEYADLQNIFLGGDSAGGNIAHHMAIRVGLDPVVGIRVRGAILLHPYFWGKERVGTESDSIKPEVIAMLDDLWSVVDPGSSGADDPLINPGMDSRIAGMGCSKILVCVGGDDFMRERNWYYKQVIEKSGWKGELEVVEDKGEGHLACIFVMSSEDEIIKEFPGIIRLFKDGRFQKLHVPVNVPAGIDPSSGVDSKDVVFSLENNVSARLYIPKTTTQNRKLPLVIYFHGSGFLIESIASSTYHNFLNLVVAESDVVVVSVGYRLAPEFPLPTAYEDSWEAIKWVAEHCNGDGPDPWLNEYADLQNIFLAGDSAGGNIAHHMAIRVGLDHVAGIRVRGAILLHPYFWGKERVGTESNSIKPEVIAMLDDLWSVVDPGSSGADDPLINPGMDPRIVGMGCSKILVCVGGDDFMRERNWYYKQVIEKSGWKGELEVVEDKGEGHGFFILNPSSPNACALRTRICTFINN
>CtAH06T0134900.1
MSFSFSSLPLAHPEEILHDLSPFMLIHQNGRIERLALEETIPPSTDYSTGVRSKDVQISSETGLSARLYLPATNTSQKHNLPLVVYFHGGGFVVGRASGTLFQPFLSRLAFEANVVVVSVDYRRAPEHPLPTAYDDSWDAIKWVVSHATGNGHEPWLTDFVDFERVFFGGESAGANIAHQMAMRIALENDEGVKLSGIVLIHPYFWGETLIGGEVVADVRESNVLGNLWRVANPDTTGRSLTSFAGRRSPEVADGGR
MTSEDEIIKELPGIIRLFKDGRFQKLHVPVLVPAGIDPTSGVDSRDVVFSPENNVSARLYLPKTTPPNRKLPLVIFFHGGGFIVESAASSTYHNFLNLVAAESSAVVVSVDYRLAPEFPLPAAYEDSWEAIKWVAGHGNGDGPDPWLNEHADLQNVFLAGDSAGGGAAAPSGSYVAPPLGSGPVAGIGVRGAILLHPYFWGIERIGTESDSLKPEMIATLDGLWSMADPESSGPDDPLINPGMDPRIAGMGCSKILVCVGGNDFMRERNWYYKQVIEESGWKGELEVVEDKGEGHVFFLFYPSSPNACALRTRICTFINN
>CtAH10T0263800.1
MGGHVVDDCRGVLKVFGDGSIWRSTEPSFQVPVVDDGSVLWKDVVFDQPNNLSLRLYKPAPIGPDRPDKLPVFYYIHGGGFCIGSRTWPNCQNYCFKLARDLGAVVVAPDYRLAPESRLPLANEDGFSAVKWLRDQATGSEPDPWLVESADFGRVFVCGDSAGGNIAHNVAVRLGAGSKGLDPVRVRGYVLLAPFFGGTVLTRSEAEGPDDAFLNWELIDRFWRLSIPVGDTMDHPLVNPFGPVSVDLEPVELDPILVVCGGCDLLKDRAKDYAERLKSWGKKVTYEEFEGQQHGNGMTYISSFIQSKG
>CtAH11T0185300.1
MGSLPHVVEDCYGLVQIFSDGSIHRHEKIDFSAFPVKDDGSVVWKDYCYDLLHGLRLRFYKPKSSTTAAKLPAIFYLRGGGFCLGSFAWPNIHNSCLRLSSALQAVVVAPDYQLAPEHRLPAAMDDSLAALKWLQDLGRNPKGGGDGDVVDCVDFDRFFVAGDSSGGNIAHHLAVRLGPGSPELAPIKVRGYVMMAPFFGGKERTRSEAEGSPETFLDIDILDMFWRMSLPVGNTADHPYANPFGPQSPSLEPIKLDPILLIAGGDEIMKDRVELYAKRLKELGKMAQYVEFKGKQHGFFTNEPYSNVSDSFLKLIKDFMFEHSS
>CtAH03T0075000.1
MTSIFGSGKIITSDQYLFQINGFLRVHTDGRCERLVGIKTVPSGIDPSTGVHSKDVVISPETNLSVRLYFPKTASPNPKQKLPVVIYFHGGGFAVESARSPTYHPTLNLLAAKSGVIVVSVDYRLAPEHPLPIGYNDSWEAIKWVATHGSKEPWLDDDVADFQKVFLAGDSAGANIAHNMAIRFGSDPIGSIKLNGIILLHPFFGGEDPIGSECGKHKQLKAYTDQFWKLANPDSGSGLDDPWFNPEKDPKVGGLGCGKILVCVAEKDSLRDRGINYRDLMGRSGWNGELEVMETKGEDHVFFLFNPSCENACSLHNKVCSFINQTHHQQSRC
>CtAH03T0074900.1
MNQENIKLQINHHRYQLSSRKKDEVKQRFAPIHRPMTTHSNNHPAMESTQHEILHDFHPILRVYKDGHVHKMTTTPILPPSDDPQTTVRSKDVVISAHPKVAARLYLPKTTTTKLPLLIYIHGGAFAIESAFSTLYHNHLNTLTAAANVAAVSIEYRLAPEHPIPACYDDCWETLKWVLDTQDPWIRNHADLSRVFLAGDSAGANIAHNVMVRFSENGAGSGLKQGRIYVEPRFATGLKIMGMALIHPFFSFDEEDKLWMYLCPGTSGLDDPRMNPAADPGLLAKMVCEKVVVCTAGKDHLRDRGWSYYEALKKSGWGGQLQIMESEDEEHCFHLFNPTCQRAQALNVAGPISGHTTSGIHLRLRHPPSSPPSDSGPPLPELDQRPRQSRRRRRSDWG
>CtAH05T0192700.2
MGSDQEQDVAFELLPFLRLHKDGTVERLYHPTLCPPSPVAATTTTTTTGGVCSKDVIISPNVSARLYLPNNNLPLLSSGGKKLLPILVYFHGGGFCIESAFSTLCHRYMTTLASLANALIVSVDYRLAPENPLPAAYQDSWAALQWVASHANKEHNQRDEPWLVQHADFDRLYIGGDSAGANISHHMAMRAGTENLHGGVKILGAFLSYPYFLGSNPLGSESVTGHEMSLLHKTWMIVYPGAPDGIDNPLINPFAKTAPCLMGLGCRRLIVCVASEDELKDRGVHYHDAVKESGWQGEISLFEAQGEGHCFHIFNPETKNAKEMFKRLAGFLQEC
>CtAH05T0096900.1
MSPADEIIKEIPGLVRVFKDGRIEKFRDPVLVPAGIDPSTGVISKDVVFSPENNNFARIYIPKTTVTQARKLPLLIYFHGGGFVIESAASSTYQGFLNLVAAESGAVVVSADYRLAPEFPLPAAYEDAWAAIGWVAGHGDGDGPDPWLNQYADLQNVFLAGDSAGGNIAHHMAIRAGSDPLPGLRIRGNILLHPYFWGKERVGTESEFIEESVVAILDDLWGLVHPGGVGPEDPFINPGMDPNVAGMGCPKILVCVGGKDVLKERGWWYKQVIEKSGWEGELEVVEDKGEDHVFFLMNPCAPNACTLRTRICTFINN
>CtAH05T0057100.1
MYTIHHFSNFTNLFFTLMASNKELSFELPGVIRVYNDGSVERLMISPYVSPSLQDPINGGISSKDIAISPHVSVRLYLPKSAVPTSSQKLPVFVYIHGGGFVVGSAFTLFEHNYLNTIVSHINALVISVEYRLAPEHLLPTAYEDCWTALQWVASHATSNGKNSENQEPWLVEFGDFERLYIGGDSAGANIVHNLAMRAGRESLNGDVKILGAFLGCPYFWGSSYGVESLPCGCWMMAYPEAEGGIDSPMINPFVGDGDGRGFAAEYGVRKLLVVATEKDEFRDIDVEYFESVKGSEWGGEVELLEIEGESHCFYAMDTTSEKAKVVMERLASFVELSFEIPNLIRVYKDGSVERLMISPYVSPSLQDPVNGISTKDIAISPHVSVRLYLPKSAAPTSSRKLPVFVYVHGGGFVVGSAFTLLEHSYLNAIVSHTNALVISVEYRLAPEHLLPAAYEDCWTALQWVASHATNHGENSENDQEPWLVEFGDFERLYIGGDSAGANIVHNLALQAGRESLNGGVKILGAFLGCPYFWSSSYGVESLAYGCWMMAYPQAEGGIDNPMINPFVGGGGGRGFAAEYGVRKLLVVAAEQDMLRDINVKYFEGVKGSDWDGEVEFLEIEGENHCFYAMDTTSEKAK
>CtAH05T0096700.1
MSSEDEIIKEVPGIIRLFKDGRFQKLHVPVMVPAGVDPTSGVDSKDVMFSPQYNVSARVYIPKTTPPNRKLPLVIYFHGGGFIIESAASSTYHNFLNLVVAESEAVLVSVDYRLVPEFPLSAAYEDSWEAIKWVAEHGNGDGPDPWLNEYADLQNIFLGGDSAGGNIAHHMAIRVGLDPVVGIRVRGAILLHPYFWGKERVGTESDSIKPEVIAMLDDLWSVVDPGSSGADDPLINPGMDSRIAGMGCSKILVCVGGDDFMRERNWYYKQVIEKSGWKGELEVVEDKGEGHLACIFVMSSEDEIIKEFPGIIRLFKDGRFQKLHVPVNVPAGIDPSSGVDSKDVVFSLENNVSARLYIPKTTTQNRKLPLVIYFHGSGFLIESIASSTYHNFLNLVVAESDVVVVSVGYRLAPEFPLPTAYEDSWEAIKWVAEHCNGDGPDPWLNEYADLQNIFLAGDSAGGNIAHHMAIRVGLDHVAGIRVRGAILLHPYFWGKERVGTESNSIKPEVIAMLDDLWSVVDPGSSGADDPLINPGMDPRIVGMGCSKILVCVGGDDFMRERNWYYKQVIEKSGWKGELEVVEDKGEGHGFFILNPSSPNACALRTRICTFINN
>CtAH06T0134900.1
MSFSFSSLPLAHPEEILHDLSPFMLIHQNGRIERLALEETIPPSTDYSTGVRSKDVQISSETGLSARLYLPATNTSQKHNLPLVVYFHGGGFVVGRASGTLFQPFLSRLAFEANVVVVSVDYRRAPEHPLPTAYDDSWDAIKWVVSHATGNGHEPWLTDFVDFERVFFGGESAGANIAHQMAMRIALENDEGVKLSGIVLIHPYFWGETLIGGEVVADVRESNVLGNLWRVANPDTTGRSLTSFAGRRSPEVADGGR
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University