Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Carpinus fangiana
Species name
Carpinus fangiana is a species of eudicot in the family Betulaceae (birch family).
Species info
Gene sequence info
Carpinus_fangiana.CHS.fa
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>rna-gnl|WGS:VIBQ|Cfa005174.t1
MSEEILKKYPELAIEGSATVKQRLDICNDAVTRMAVEASQACIKNWGRPMSDITHLVYVSSSEARLPGGDLYLAKGLGLGPETQRVMLYFMGCSGGVSGLRVAKDIAENNPGSRVLLATSETTIIGYKPPSAARPYDLVGVALFGDGAGAMIIGSDPISGNERPLFELHTAIQHFLPDTEKTIDGRLTEEGISFKLARELPQIIEDNIEGFCKKLIKFVGFPDKDYNKMFWAVHPGGPAILNRIEKRLELSPEKLNASRRALMDYGNASSNTIVYVLEYMLEESLMIKKENGDNEWGLILAFGPGITFEGILARNLTV
>rna-gnl|WGS:VIBQ|Cfa007149.t1
MASVEEIRKAQRAHGPANILAIGTATPSNCVSQADYPDYYFRITNSEHMTELKEKFRRMCDKSMIKKRYMHLDENILKENPNMCAYMAPSLDARQDIVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPTDTHLDSLVGQALFGDGAAAIIVGADPDTSIERPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGIISKNIEKSLAEAFAPLGIRDWNSLFWVAHPGGPAILDQVESKLGLKEEKLRATRHVLSEYGNMSSACVLFILDEMRKNSMEEGKATTGEGLEWGVLFGFGPGLTVETVVLHSIPVPVVANH
>rna-gnl|WGS:VIBQ|Cfa007150.t1
MASVEEIFNAQRSQGPANVLAIGTANPSNCIYQADFPDYYFRVTKSEHMTDLKRKFKRICEKSMIRKRHMHVTEDILKENPNMCTFKEPSLDARQEIGVVELPKLAKEAALKAIKEWGQPKSKITHLIFSTTLGISDMPGADYQLTKLLDLKPSVKRIMMYQHGCFGGGTVLRVAKDFAENHKGARVLAVCAEITASCFRGPSESHLDSLVGQSLFGDGAAAVIVGADPDTSVERPLFQLVSATQTLLPDSDGAVEGHMLERGLTFHLLKDLPKIASTNIEKSLVESFSPIGISDWNSLFWIVHPGGPAILDQVEGRLGLEEEKLRASRHILSEYGNMSTACVLFILDEIRKKSVEEGKATTGGGLDWGVLFGLGPGLTVETVVLHSVPVETIN
>rna-gnl|WGS:VIBQ|Cfa011116.t1
MSRINGNGDPDRLYPAQTRRLPSPGKATILALGKAFPSQLIPQECLVEGYIRDTKCVDSSIKEKLERLCKTTTVKTRYTVMSKEILEKYPELATEGSPTIKQRLEIANPAVLEMAKEASLACIKEWGRPAQDITHIVYVSSSEIRLPGGDLHLSSQLGLRSDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRILLTTSETTILGFRPPNKERPYDLVGAALFGDGAAAVIIGSNPLTGQESPFMELNYAVQQFLPGTHNVIDGKLSEEGINFKLGRDLPQKIEENIEEFCKKLMLKADLKEFNDLFWAVHPGGPAILNRLETTLKLTPDKLECSRRALMDYGNVSSNTIFYVMDYMREELKRSSGREEWGLALAFGPGITFEGILVRSL
>rna-gnl|WGS:VIBQ|Cfa014897.t1
MACNISGDKSMIKKRYMYLTEEILKEHPNICAYMAPSLDARQDMVVVEITKLGKEAIVKAIKEWGWPKSKITYLVFCTTSGVDMPGADYQLTKLLGLCPFVKRLMMYQQGCFAGGTVLCLAKDLAENNKGACVLIVCLEIIAVTFHGPNDAHLDSLVGQYKLWSTTISTVSPGPNPKSTPHSSPSPVVFSPFSTDFLLMSSKINNTQALDILPNSLST
>rna-gnl|WGS:VIBQ|Cfa014895.t1
MVTVEEVRKAQRAEGPATVMAIGTATPPNCVEQSTYPDYYFRITNSEHKTELKEKFQRMCDKSMIKKRYMYLTEEILKEHPNICAYMAPSLDARQDMVVVEIPKLGKEAAVKAIKEWGQPKSKITHLVFCTTSGVDMPGADFQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDAHLDSLVGQALFGDGAAAIIVGADPVPEVEKPLFELVSTAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFQPLGISDWNSLFWIAHPGGPAILDQVESKLGLKSEKLRATRHVLSEFGNMSSACVLFILDDMRRKSVENGLKTTGEGLEWGVLFGFGPGLTVETVVLHSLST
>rna-gnl|WGS:VIBQ|Cfa014899.t1
MVTVEEVRKAQRAEGPATVMAIGTATPPNCVEQSTYPDYYFRITNSEHKTELKEKFQRMCDKSMIKKRYMYLTEEILKEHPNICAYMAPSLDARQDMVVVEIPKLGKEAAVKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDAHLDSLVGQALFGDGAAAIIVGADPVPEVEKPLFELVSTAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFQPLGISDWNSLFWIAHPGGPAILDQVESKLGLKSEKLSATRHVLSEFGNMSSACVLFILDDMRRKSVENGLKTTGEGLEWGVLFGFGPGLTVETVVLHSLST
>rna-gnl|WGS:VIBQ|Cfa014892.t1
MVTVEEVHKAQRVEGPAIVKAIGTATPPNCVENGKVISVVACNISGDKSMIKKRYMYLTEEILKEHPNICAYMAPSLDARQDTVVVEIPKLGKEAAVKAIKEWGQPKSKITHLVFCTTIGVDMPGVDYQLTKLLSFRPSMKRLMMYQQGCFAGGTVLCLAKDLAENNKGACVLVALFGDGAAAIIVGVDPVPEVEIFELVYTAQTILPDSDEAIDSHLREVGLTFHLLKDVTGLISKNIEKSLVSAFKPLGISDWNYLFWIAHPGGPTIFDQVESKRKSVENGLKTTGEGLEWGVLFGFGPGLTVKTVVLHSLST
>rna-gnl|WGS:VIBQ|Cfa014898.t1
MVTVEEVCKAQRAEGPATVMAIGTATPPNCMEQSTYPDYYFRITNSEHKTKLKEKFK
MSEEILKKYPELAIEGSATVKQRLDICNDAVTRMAVEASQACIKNWGRPMSDITHLVYVSSSEARLPGGDLYLAKGLGLGPETQRVMLYFMGCSGGVSGLRVAKDIAENNPGSRVLLATSETTIIGYKPPSAARPYDLVGVALFGDGAGAMIIGSDPISGNERPLFELHTAIQHFLPDTEKTIDGRLTEEGISFKLARELPQIIEDNIEGFCKKLIKFVGFPDKDYNKMFWAVHPGGPAILNRIEKRLELSPEKLNASRRALMDYGNASSNTIVYVLEYMLEESLMIKKENGDNEWGLILAFGPGITFEGILARNLTV
>rna-gnl|WGS:VIBQ|Cfa007149.t1
MASVEEIRKAQRAHGPANILAIGTATPSNCVSQADYPDYYFRITNSEHMTELKEKFRRMCDKSMIKKRYMHLDENILKENPNMCAYMAPSLDARQDIVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPTDTHLDSLVGQALFGDGAAAIIVGADPDTSIERPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGIISKNIEKSLAEAFAPLGIRDWNSLFWVAHPGGPAILDQVESKLGLKEEKLRATRHVLSEYGNMSSACVLFILDEMRKNSMEEGKATTGEGLEWGVLFGFGPGLTVETVVLHSIPVPVVANH
>rna-gnl|WGS:VIBQ|Cfa007150.t1
MASVEEIFNAQRSQGPANVLAIGTANPSNCIYQADFPDYYFRVTKSEHMTDLKRKFKRICEKSMIRKRHMHVTEDILKENPNMCTFKEPSLDARQEIGVVELPKLAKEAALKAIKEWGQPKSKITHLIFSTTLGISDMPGADYQLTKLLDLKPSVKRIMMYQHGCFGGGTVLRVAKDFAENHKGARVLAVCAEITASCFRGPSESHLDSLVGQSLFGDGAAAVIVGADPDTSVERPLFQLVSATQTLLPDSDGAVEGHMLERGLTFHLLKDLPKIASTNIEKSLVESFSPIGISDWNSLFWIVHPGGPAILDQVEGRLGLEEEKLRASRHILSEYGNMSTACVLFILDEIRKKSVEEGKATTGGGLDWGVLFGLGPGLTVETVVLHSVPVETIN
>rna-gnl|WGS:VIBQ|Cfa011116.t1
MSRINGNGDPDRLYPAQTRRLPSPGKATILALGKAFPSQLIPQECLVEGYIRDTKCVDSSIKEKLERLCKTTTVKTRYTVMSKEILEKYPELATEGSPTIKQRLEIANPAVLEMAKEASLACIKEWGRPAQDITHIVYVSSSEIRLPGGDLHLSSQLGLRSDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRILLTTSETTILGFRPPNKERPYDLVGAALFGDGAAAVIIGSNPLTGQESPFMELNYAVQQFLPGTHNVIDGKLSEEGINFKLGRDLPQKIEENIEEFCKKLMLKADLKEFNDLFWAVHPGGPAILNRLETTLKLTPDKLECSRRALMDYGNVSSNTIFYVMDYMREELKRSSGREEWGLALAFGPGITFEGILVRSL
>rna-gnl|WGS:VIBQ|Cfa014897.t1
MACNISGDKSMIKKRYMYLTEEILKEHPNICAYMAPSLDARQDMVVVEITKLGKEAIVKAIKEWGWPKSKITYLVFCTTSGVDMPGADYQLTKLLGLCPFVKRLMMYQQGCFAGGTVLCLAKDLAENNKGACVLIVCLEIIAVTFHGPNDAHLDSLVGQYKLWSTTISTVSPGPNPKSTPHSSPSPVVFSPFSTDFLLMSSKINNTQALDILPNSLST
>rna-gnl|WGS:VIBQ|Cfa014895.t1
MVTVEEVRKAQRAEGPATVMAIGTATPPNCVEQSTYPDYYFRITNSEHKTELKEKFQRMCDKSMIKKRYMYLTEEILKEHPNICAYMAPSLDARQDMVVVEIPKLGKEAAVKAIKEWGQPKSKITHLVFCTTSGVDMPGADFQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDAHLDSLVGQALFGDGAAAIIVGADPVPEVEKPLFELVSTAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFQPLGISDWNSLFWIAHPGGPAILDQVESKLGLKSEKLRATRHVLSEFGNMSSACVLFILDDMRRKSVENGLKTTGEGLEWGVLFGFGPGLTVETVVLHSLST
>rna-gnl|WGS:VIBQ|Cfa014899.t1
MVTVEEVRKAQRAEGPATVMAIGTATPPNCVEQSTYPDYYFRITNSEHKTELKEKFQRMCDKSMIKKRYMYLTEEILKEHPNICAYMAPSLDARQDMVVVEIPKLGKEAAVKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDAHLDSLVGQALFGDGAAAIIVGADPVPEVEKPLFELVSTAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFQPLGISDWNSLFWIAHPGGPAILDQVESKLGLKSEKLSATRHVLSEFGNMSSACVLFILDDMRRKSVENGLKTTGEGLEWGVLFGFGPGLTVETVVLHSLST
>rna-gnl|WGS:VIBQ|Cfa014892.t1
MVTVEEVHKAQRVEGPAIVKAIGTATPPNCVENGKVISVVACNISGDKSMIKKRYMYLTEEILKEHPNICAYMAPSLDARQDTVVVEIPKLGKEAAVKAIKEWGQPKSKITHLVFCTTIGVDMPGVDYQLTKLLSFRPSMKRLMMYQQGCFAGGTVLCLAKDLAENNKGACVLVALFGDGAAAIIVGVDPVPEVEIFELVYTAQTILPDSDEAIDSHLREVGLTFHLLKDVTGLISKNIEKSLVSAFKPLGISDWNYLFWIAHPGGPTIFDQVESKRKSVENGLKTTGEGLEWGVLFGFGPGLTVKTVVLHSLST
>rna-gnl|WGS:VIBQ|Cfa014898.t1
MVTVEEVCKAQRAEGPATVMAIGTATPPNCMEQSTYPDYYFRITNSEHKTKLKEKFK
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University