Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Cardamine hirsuta
Species name
Hairy bittercress (Cardamine hirsuta) is a species of eudicot in the family Brassicaceae (mustard family).
Species info
Gene sequence info
Cardamine_hirsuta.HIDH.fa
Download
>CARHR039690.1
MLRRIIDPSSLASPSLFLRFFRQFPSSYSSPITISISGSNLRRLHSPTTLRFICSHSSSDIVYENHPFVRIFKDGRVERLSGTEIVPPSLNTQNDVVSKDVTYSPNHNLSVRLFLPNKSTEVSTGNKLPLLIYIHGGAWIIGSPFSPIYHNFLTEVVKSANCLAVSIQYRRAPEDPVPAAYDDSWSAIQWIFSHFNGSGPEDWINKYADFNRVFLAGDSAGGNISHHMAMRAGKEKLKPRIKGTVIAHPAFWGTDPVDEHDVQDRDYRNRIAEVWEKLASPNSVDGTDDPLFNVVGSGSDFSGLGCEKVLVAVAGKDVFVRQGLAYAAKLKKSGWEGEVEVMEEEDEDHCFHLLNPNSENAPKFLKKFVEFISG
>CARHR039680.1
MESNLTTNHHLPFIRIHKNGHVERLRGNEIVPASLNPQNDVVTKDVVYSPEHDLSVRMFLPNKPIDNKLPLLIYFHGGAYIMQSPFSPVYNNHLTEVVKATNCLAVSVQYRRAPEHPIPAAYDDSWSAIQWIFGGKDDWINEYADFDSVFIAGDSAGANIAHHMGIRAGKEKLNPRIKGIVMVHPGFWGKDPIDERDVQDRKIRSGVEDIWEKIVSPNSVDGVNDPWFNVVGSGSDISGLGCGKVLVAVAGKDVFWRQGLAYAAKLEKSGWKGGIEVVEEEEEGHCFHLQSPDSENALKLMKRFVEFITYVES
>CARHR039710.1
MDSEIASEFLPFIRTYKDGHTERLIGTEIIPASLDPTNDVVSKDVIYSTEHNLSVRLFLPNNKSTELVGAYKLPLLIYIHGGAWIIESPFSPIYHNYLTDLVKSANCLAVSIQYRRAPEDPIPAAYEDAWSAIQWIFSHTNGSGSEEWINKHADFNRVFIAGDSAGGNISHHMAMRAGKEKLEPRIKGIVIVHPAFWGTDPVDEHDVQDIEMRNGIAEVWEKIASPNSVNGTDDPLFNVNGSGSDFSGLICEKVLVAVAGKDVFVRQGLAYAAKLKKSGWEGEVEVMEEEDEEHVFHLQNPNSEKALKFLNKFVEFIIG
>CARHR019790.1
MDSEIAFDYSPRFRVFKNGQIQRLVPETFVPPSLNPENGVGSKDVVYSPEKNLSLRIYLPHTTGDEKIPLLIYFHGGGFIMETAFSSMYHTFLTSTVSASDCIAVSVDYRRAPEHPIPIAYEDSWDAIQWIFTHVPGSGSEEWLNKHADFSRVIFAGDSAGANIVHHMGIRAGKEKLMISGMILCHPYFLSKALIEEMEVGAMRYMEGLWEIASANCENGVEDPWINVFGSGISGLGCGRVLVMVAGNDVLAKGGLGYVAKLEMSGWEGKVEVIETKDEDHVFHLRNPNSDNARRLLQSFVEFVKSD
>CARHR037040.1
METTKKQVSLELLPWLVVHTDGTIERLAGTEVCPPGLDSETRVLSKDIIIEAKTGLTARIYRPDSIQPGQKLPLALYFHGGAFLISSASFPCYHTNLNKLVAEANIIAVSVNYRLAPEHPLPTAYEDSWNTLQTIKTINETWINDYADLNRLFLLGDSAGANISHHLAFKAKQSDQIIKIKGIGLIHPYFWGTKPIGSEAEDEAKKQMVDGWWKFVCPSEKGSDDPWINPFADESPDLEGLDCERVMITVTEKDILRDRGKMYYERLVKSKWKGKVEMMETKGKDHVFHIFEPDCEEALEMVRCLALFINQVEV
>CARHR061420.1
MGATTLTNVTTINHNNTNIHGPVVDEVQGLIKVYKDGHVERPQIVPCVDPSLPLELGVACSDVCIDKLTNVWARLYVPMMTTKSSVSKLPFLVYFHGGGFCIGSASWSCYHEFLARLSARSRCLVMSVNYRLAPENPLPAAYEDGVNAILWLNKARNDNLWAKLCDFDRIFLAGDSSGGNIAHHVAARLAAAEDLAVLKIEGTILIQPFFGGEARTESERRVGNIKSSGLTLAASDAWWKLALPRGATRDHPYCKAVKIKSTVNMRTLVCVAEMDLLMDRNMEMCDGNEKMIKRVVYRGVGHAFHILGKTQLAHTTTLEMLCHIDAFIHNYECL
>CARHR157450.1
MDSEILADYSPMLKIYKSGRVERIMGETTVPPSSEPQNGVISKDVVYSPDNNLSLRVYLPEKATVTAAGEKLPLLVYFHGGGFIIETAFSPTYHTFLTAAVSASDCVAVSVDYRRAPEHPIPISYDDSWTALKWVFSHIAGSGEEAWLNKHADFTKVFLAGDSAGANIAHHMAMKAAKEKLSPGLNGSGISGIILVHPYFWSRTPIDEKETKDATVRMKIDAIWSMASPNSKDGSDDPLINVVQSESVDLSELGCGKVLVMVAEKDALARQGWGYVAKLEKSGWKGKVKLVESEGEDHVFHLMKPTCDKAVEAMHMFSGFLNGVN
>CARHR145890.1
MDSEIAFDRSPAYRVYKSGRIERLLGETTVPPSLTPQNGVVSKDVIFSPENNLSCRIYLPEKISTDKKLPMLIYFHGGGFIIETAFSPTYHTFLTSTVAAANCLTISVDYRRAPEFPIPIPYEDSWDSLKWVLSHISGTGQETWINKHGDFGKLYLAGDSAGGNIAHHLTTRAKRENLEKSVISGIILIHPYFWGKTPIDEFEIRDVARKKGVEGSWGIASPNSKEGVDDPWLNVVGSDDSDLSGLGCGRVLVMVAGDDLFVRQGWGYAAKLKKSGWEGEEVEVMETKDEGHVFHLKDPNTDNARQVVKKLAEFIN
>CARHR197230.1
MATISFSHNHQSSNNRRSGSHHHRHGPVVEEIEGLIKVFNDGCVERPPIVPTVSPTLHPSTKATAFDIKISNDTSTRVYIPDAAAASPSVVTLPLLVYFHGGGFCVGSAAWSCYHDFLTSLAVKARCVVVSVNYRLAPEHRLPAAYDDGVNVFSWLVKQQITNGGYSWVSKCNLSNVFLAGDSAGANIAYQVAVRITGSGKFVNTLNLKGIILIHPFFGGESRTSSEKQQHNSKSSSALTLSASDTYWRLALPRGANRDHPWCNPLMPGCLREAKLPRTMVFMAELDILKDRNLEMCKVMRSHGKRVEGIVHGGVGHAFHILDNSSVSRDRIHDMMCRLHNFIHPL
MLRRIIDPSSLASPSLFLRFFRQFPSSYSSPITISISGSNLRRLHSPTTLRFICSHSSSDIVYENHPFVRIFKDGRVERLSGTEIVPPSLNTQNDVVSKDVTYSPNHNLSVRLFLPNKSTEVSTGNKLPLLIYIHGGAWIIGSPFSPIYHNFLTEVVKSANCLAVSIQYRRAPEDPVPAAYDDSWSAIQWIFSHFNGSGPEDWINKYADFNRVFLAGDSAGGNISHHMAMRAGKEKLKPRIKGTVIAHPAFWGTDPVDEHDVQDRDYRNRIAEVWEKLASPNSVDGTDDPLFNVVGSGSDFSGLGCEKVLVAVAGKDVFVRQGLAYAAKLKKSGWEGEVEVMEEEDEDHCFHLLNPNSENAPKFLKKFVEFISG
>CARHR039680.1
MESNLTTNHHLPFIRIHKNGHVERLRGNEIVPASLNPQNDVVTKDVVYSPEHDLSVRMFLPNKPIDNKLPLLIYFHGGAYIMQSPFSPVYNNHLTEVVKATNCLAVSVQYRRAPEHPIPAAYDDSWSAIQWIFGGKDDWINEYADFDSVFIAGDSAGANIAHHMGIRAGKEKLNPRIKGIVMVHPGFWGKDPIDERDVQDRKIRSGVEDIWEKIVSPNSVDGVNDPWFNVVGSGSDISGLGCGKVLVAVAGKDVFWRQGLAYAAKLEKSGWKGGIEVVEEEEEGHCFHLQSPDSENALKLMKRFVEFITYVES
>CARHR039710.1
MDSEIASEFLPFIRTYKDGHTERLIGTEIIPASLDPTNDVVSKDVIYSTEHNLSVRLFLPNNKSTELVGAYKLPLLIYIHGGAWIIESPFSPIYHNYLTDLVKSANCLAVSIQYRRAPEDPIPAAYEDAWSAIQWIFSHTNGSGSEEWINKHADFNRVFIAGDSAGGNISHHMAMRAGKEKLEPRIKGIVIVHPAFWGTDPVDEHDVQDIEMRNGIAEVWEKIASPNSVNGTDDPLFNVNGSGSDFSGLICEKVLVAVAGKDVFVRQGLAYAAKLKKSGWEGEVEVMEEEDEEHVFHLQNPNSEKALKFLNKFVEFIIG
>CARHR019790.1
MDSEIAFDYSPRFRVFKNGQIQRLVPETFVPPSLNPENGVGSKDVVYSPEKNLSLRIYLPHTTGDEKIPLLIYFHGGGFIMETAFSSMYHTFLTSTVSASDCIAVSVDYRRAPEHPIPIAYEDSWDAIQWIFTHVPGSGSEEWLNKHADFSRVIFAGDSAGANIVHHMGIRAGKEKLMISGMILCHPYFLSKALIEEMEVGAMRYMEGLWEIASANCENGVEDPWINVFGSGISGLGCGRVLVMVAGNDVLAKGGLGYVAKLEMSGWEGKVEVIETKDEDHVFHLRNPNSDNARRLLQSFVEFVKSD
>CARHR037040.1
METTKKQVSLELLPWLVVHTDGTIERLAGTEVCPPGLDSETRVLSKDIIIEAKTGLTARIYRPDSIQPGQKLPLALYFHGGAFLISSASFPCYHTNLNKLVAEANIIAVSVNYRLAPEHPLPTAYEDSWNTLQTIKTINETWINDYADLNRLFLLGDSAGANISHHLAFKAKQSDQIIKIKGIGLIHPYFWGTKPIGSEAEDEAKKQMVDGWWKFVCPSEKGSDDPWINPFADESPDLEGLDCERVMITVTEKDILRDRGKMYYERLVKSKWKGKVEMMETKGKDHVFHIFEPDCEEALEMVRCLALFINQVEV
>CARHR061420.1
MGATTLTNVTTINHNNTNIHGPVVDEVQGLIKVYKDGHVERPQIVPCVDPSLPLELGVACSDVCIDKLTNVWARLYVPMMTTKSSVSKLPFLVYFHGGGFCIGSASWSCYHEFLARLSARSRCLVMSVNYRLAPENPLPAAYEDGVNAILWLNKARNDNLWAKLCDFDRIFLAGDSSGGNIAHHVAARLAAAEDLAVLKIEGTILIQPFFGGEARTESERRVGNIKSSGLTLAASDAWWKLALPRGATRDHPYCKAVKIKSTVNMRTLVCVAEMDLLMDRNMEMCDGNEKMIKRVVYRGVGHAFHILGKTQLAHTTTLEMLCHIDAFIHNYECL
>CARHR157450.1
MDSEILADYSPMLKIYKSGRVERIMGETTVPPSSEPQNGVISKDVVYSPDNNLSLRVYLPEKATVTAAGEKLPLLVYFHGGGFIIETAFSPTYHTFLTAAVSASDCVAVSVDYRRAPEHPIPISYDDSWTALKWVFSHIAGSGEEAWLNKHADFTKVFLAGDSAGANIAHHMAMKAAKEKLSPGLNGSGISGIILVHPYFWSRTPIDEKETKDATVRMKIDAIWSMASPNSKDGSDDPLINVVQSESVDLSELGCGKVLVMVAEKDALARQGWGYVAKLEKSGWKGKVKLVESEGEDHVFHLMKPTCDKAVEAMHMFSGFLNGVN
>CARHR145890.1
MDSEIAFDRSPAYRVYKSGRIERLLGETTVPPSLTPQNGVVSKDVIFSPENNLSCRIYLPEKISTDKKLPMLIYFHGGGFIIETAFSPTYHTFLTSTVAAANCLTISVDYRRAPEFPIPIPYEDSWDSLKWVLSHISGTGQETWINKHGDFGKLYLAGDSAGGNIAHHLTTRAKRENLEKSVISGIILIHPYFWGKTPIDEFEIRDVARKKGVEGSWGIASPNSKEGVDDPWLNVVGSDDSDLSGLGCGRVLVMVAGDDLFVRQGWGYAAKLKKSGWEGEEVEVMETKDEGHVFHLKDPNTDNARQVVKKLAEFIN
>CARHR197230.1
MATISFSHNHQSSNNRRSGSHHHRHGPVVEEIEGLIKVFNDGCVERPPIVPTVSPTLHPSTKATAFDIKISNDTSTRVYIPDAAAASPSVVTLPLLVYFHGGGFCVGSAAWSCYHDFLTSLAVKARCVVVSVNYRLAPEHRLPAAYDDGVNVFSWLVKQQITNGGYSWVSKCNLSNVFLAGDSAGANIAYQVAVRITGSGKFVNTLNLKGIILIHPFFGGESRTSSEKQQHNSKSSSALTLSASDTYWRLALPRGANRDHPWCNPLMPGCLREAKLPRTMVFMAELDILKDRNLEMCKVMRSHGKRVEGIVHGGVGHAFHILDNSSVSRDRIHDMMCRLHNFIHPL
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University