Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Capsicum annuum
Species name
Capsicum annuum is a species of eudicot in the family Solanaceae (nightshade family).
Species info
Gene sequence info
Capsicum_annuum.COMT.fa
Download
>rna-XM_016708725.1
MGSTSHSLTQTEDEAFVFAMQLASASVLPMVLKAAVELDLLEIMAKAGPGAFISPSELAAQLPTKNPEAPVMLDRMFRLLATYSLLNCTLRTLPDGRVERLYSLAPVCKFLTKNGDGVSIAPILLMNQDKVLMESWYHLTDAVLDGGVPFDKAYGMTTFEYRGTDPRFNKVFNCGMSDHTTLSMKKILEDYTGFEGLNSIVDVGGGTGATVNMIVSKYPSIKGINFDLPHVIRDAPSYPGVEQVGGDMFVSVPKADAIFMKWICHDWSDDHCIKLLKNCYEALPANGKVIIVECILPEAPDTSAATKSKVHGDIIMLAHNPGGKERTEK
>rna-XM_016708727.1
MDSTNQNLTQTEDEAFLFAMQLASASVLPMVLKSALELDLLEIMAKAGPGAAISPSELAAQLPTKNPEAPVMLDRMLRLLATYSVLNCTLRTLPDGRVERLYSLAPVCKLLTKNADGVSVAPLLLMNQDKVLMESWYHLTDAVLDGGVPFNKAYGMTAFEYHGTDPRFNKVFNRGMSDHSTMTMKKILEDYKGFEGLNSIVDVGGGTGATVNMIVSKYPSIKGINFDLSHVIEDAPAYPGVEHVGGDMFVSVPKADAIFMKWICHDWSDEHCLKFLKNCYEALPANGKVLVAECILPETPDTSAATKNAVHVDIVMLAHNPGGKERTEKEFEALAKGAGFTGFRRACCAYQTWVMEFHK
>rna-XM_016719694.1
MEHNQLPISGHSEKEENFAYAMQLWSSSVLPFVLHSTVELEVFEILAKANTQLSASQIVCQMPTCKNPDAANMLDRMLYVLASYSLLTYSIQQNERHYGLSAVGKFFVRDEEDGASWGPVLALLQHKVLINSLFGLKDAILEGGVPFDRMHGVNLFEYLEMDPEFSIVFNKAMINHTTLVMKNILEHYKGFEDLETLVDVGGGLGINLNMVTSKYPTIKGTNFDLPHVVQHAPSYKGVVHVGADMFESVPQGDVIFMKSILHDWSDSLCVKLLKNCYKAVPAENGKAIVVETLLPVKPDHAHASVISVSQSDLTMLAHTHGGKERSQHEFEALATEAGFKGINFVCCVCNFWVMEFYK
>rna-XM_016721347.1
MDMALSMDNIVISDEDENSMMKAMHLPCGLVLNMVLKAAIELDLFELIAKSSAQQLSSYEIASQIPTKNPNAPLVLERVLRFLASQSFLTCNIIKDDDGNNHISYKLTPLSQRFIPDKDGSSITPFLLLTMDPVGVNSWFHFKDAIVEGEIPFNKAHGMHAFEYHGKDSRFNGVFNKAMQNLTCIEMKRILECYNGFQGAKEVIDVGGGLGMSLPSIISKYPNIKGINFDLPYVIKDAPTYEGVEHIGGDMFKSVPQGEVIILKEVLHNWDDEYCVKILKNCWRALPKDGKVVLIEHIQPEYPETDLLSKETFSMDMLMMTMFDGGKERTKQQFEALAKQAGFTALKIMARAYYSWVMELYKY
>rna-XM_016722019.1
MPSSFQEMDMALSMDNISISNEDENSMMKAMHLPCGLVLNMVLKAAIELDLFELIAKSSAQQLSSYEIASQIPTKNPNAPLVLERILRFLAIQSFLTCNITNDDDGNNQTSYSLTPLSQSLIPDKDGSSIAPFLVLTVDPVGINSWFHLKDAILEGEIPFNKAHGMHAFEYHGKDSRFNGVFNKAMQNLTCIEMKRILECYNGFQGVKEIIDVGGGHGMSLASIISKYPNIKGINFDLPYVIKDAPTYEGIEHVGGDMFKSIPQGEVIILKAVLHNWDDEYCVKVLKNCWKALPKDGKVVVIEQIQAEYPEMNLLCKHSFSMDIAMMTMVGGGKERTKQQFEALAKQAGFTTALKTVARAYYSWVVELYK
>rna-XM_016721346.1
MALSMDNISISNEDENSMMKAMHLPCGLVLNMVLKAAIELDLFELIAKSSAQKLSSYEIASQIPTKNPNAPLVLERVLRFLASQSFLTCNIIKDDDGNNHTSYKLTPLSQRFIPDKDGSSITPFLLLNADPVSVNSCFHLKDAILLGEVPFNMAHGMPAIEHAGKDSRLNMLFNKAMQNLTCIEMKRILECYNGFQGAKEVIDVGGGLGMSLASIISKHPNIKGINFDLPYVIKDAPTYEGMEHVGGDMFKSVPQGEVIILKEVLHNWDDENCVKILKNCWRALPKDGKIVIIEQIQPEYPEMNLLCKHSFSMDIAMMTIFDGGKERTKQQFEALAKQAGFTTTLKIVARAYYSWVMELYKY
>rna-XM_016689990.1
MGSTSNIQLPTQSEEERNCTYAMQLLSSSVLPFVLHSTIQLDVFEILAKDKTTKLSALEIVSHIPDCKNPDAATMLDRMLYVLASYSLLDCSVIEEKNGAMKRVYGLSGVGKFFVRNEDGASMGPLLALLQDKVFIHSWFELKDAVLEGAVPFDRVHGVHAFEYPKLDPKFNDVFNKAMINHTTIIMKRILENYKGFESLKSLVDVGGGLGVNLKMITSKYPTIKGINFDLPHVVQHAPSYPGVENVGGDMFESVPEGDAIFMKWILHDWSDSHCLKLLKNCYKALPDNGKVIVVEANLPVQPDTDTTVVGVSQCDLIMMAQNPGGKERSEQEFRALATEAGFKGVNLICCVCNFWVMEFHK
>rna-XM_016687647.1
MENGNGEISNTNDKARLAIMDLAHMMSVPMSLNAVVKLKLADAIWQGGSNAPLTSAEILAKIRGPKGGGDAENLQRVLRLLTSYDVFEEHTTDDGFQRRYSLTEVGKTLVTDEDGLSHGSYVLQHHQDAILRTWPMVHEVINDSSSEPFLKANGEKPYNYYGNNPELNSLMLNAMSGVSVPFMKGMLERYDGFQEVKTLVDVGGSGGDCLKMILEKHSSIQLGINFDLPEVVKKAPQIPRIKHVGGDIFDYIPKGDAIFMKWMLPIWTDDECKQIMKNCYDALPKKGKLIACEPVVPNHTDDSQRTRALLGGDIFIMSIYRAKGKHRTEEEFRQLGQAVGFSDCRTFYGDHYFTILEFHKL
>rna-XM_016687649.1
MEKASGKTSNNNNARLAIMELANMISVPMSLNAVVKLKVADAIWEVGSNTPLSPAEILAKIRGPQGGGDSENLQRILRMLMSYGVFEEHVVDDVSQRRYSLAEVGKSLVTDVDSLSHGSYVLQHHQDALMRAWTMVHEAVNDSSTEPFVKANGEPAYNYYGKNPEMNSIMLNAMSGVSVPFMKAILEGYDGFQGVKTLVDVGGSGGDCLKMILEKHSSIQLGINFDLPEVVEKAPQIPRVKHIGGDMFNSIPKGDAIFMKWVLTTWTDDECKQIMKSCYNALPEKGKFIACEPVLPHHTDDSKRTRALLEGDIFVMTIYRAKGKHRTEEEYRQLGRSAGFADCRGFYIDHFFTTLEFQKL
MGSTSHSLTQTEDEAFVFAMQLASASVLPMVLKAAVELDLLEIMAKAGPGAFISPSELAAQLPTKNPEAPVMLDRMFRLLATYSLLNCTLRTLPDGRVERLYSLAPVCKFLTKNGDGVSIAPILLMNQDKVLMESWYHLTDAVLDGGVPFDKAYGMTTFEYRGTDPRFNKVFNCGMSDHTTLSMKKILEDYTGFEGLNSIVDVGGGTGATVNMIVSKYPSIKGINFDLPHVIRDAPSYPGVEQVGGDMFVSVPKADAIFMKWICHDWSDDHCIKLLKNCYEALPANGKVIIVECILPEAPDTSAATKSKVHGDIIMLAHNPGGKERTEK
>rna-XM_016708727.1
MDSTNQNLTQTEDEAFLFAMQLASASVLPMVLKSALELDLLEIMAKAGPGAAISPSELAAQLPTKNPEAPVMLDRMLRLLATYSVLNCTLRTLPDGRVERLYSLAPVCKLLTKNADGVSVAPLLLMNQDKVLMESWYHLTDAVLDGGVPFNKAYGMTAFEYHGTDPRFNKVFNRGMSDHSTMTMKKILEDYKGFEGLNSIVDVGGGTGATVNMIVSKYPSIKGINFDLSHVIEDAPAYPGVEHVGGDMFVSVPKADAIFMKWICHDWSDEHCLKFLKNCYEALPANGKVLVAECILPETPDTSAATKNAVHVDIVMLAHNPGGKERTEKEFEALAKGAGFTGFRRACCAYQTWVMEFHK
>rna-XM_016719694.1
MEHNQLPISGHSEKEENFAYAMQLWSSSVLPFVLHSTVELEVFEILAKANTQLSASQIVCQMPTCKNPDAANMLDRMLYVLASYSLLTYSIQQNERHYGLSAVGKFFVRDEEDGASWGPVLALLQHKVLINSLFGLKDAILEGGVPFDRMHGVNLFEYLEMDPEFSIVFNKAMINHTTLVMKNILEHYKGFEDLETLVDVGGGLGINLNMVTSKYPTIKGTNFDLPHVVQHAPSYKGVVHVGADMFESVPQGDVIFMKSILHDWSDSLCVKLLKNCYKAVPAENGKAIVVETLLPVKPDHAHASVISVSQSDLTMLAHTHGGKERSQHEFEALATEAGFKGINFVCCVCNFWVMEFYK
>rna-XM_016721347.1
MDMALSMDNIVISDEDENSMMKAMHLPCGLVLNMVLKAAIELDLFELIAKSSAQQLSSYEIASQIPTKNPNAPLVLERVLRFLASQSFLTCNIIKDDDGNNHISYKLTPLSQRFIPDKDGSSITPFLLLTMDPVGVNSWFHFKDAIVEGEIPFNKAHGMHAFEYHGKDSRFNGVFNKAMQNLTCIEMKRILECYNGFQGAKEVIDVGGGLGMSLPSIISKYPNIKGINFDLPYVIKDAPTYEGVEHIGGDMFKSVPQGEVIILKEVLHNWDDEYCVKILKNCWRALPKDGKVVLIEHIQPEYPETDLLSKETFSMDMLMMTMFDGGKERTKQQFEALAKQAGFTALKIMARAYYSWVMELYKY
>rna-XM_016722019.1
MPSSFQEMDMALSMDNISISNEDENSMMKAMHLPCGLVLNMVLKAAIELDLFELIAKSSAQQLSSYEIASQIPTKNPNAPLVLERILRFLAIQSFLTCNITNDDDGNNQTSYSLTPLSQSLIPDKDGSSIAPFLVLTVDPVGINSWFHLKDAILEGEIPFNKAHGMHAFEYHGKDSRFNGVFNKAMQNLTCIEMKRILECYNGFQGVKEIIDVGGGHGMSLASIISKYPNIKGINFDLPYVIKDAPTYEGIEHVGGDMFKSIPQGEVIILKAVLHNWDDEYCVKVLKNCWKALPKDGKVVVIEQIQAEYPEMNLLCKHSFSMDIAMMTMVGGGKERTKQQFEALAKQAGFTTALKTVARAYYSWVVELYK
>rna-XM_016721346.1
MALSMDNISISNEDENSMMKAMHLPCGLVLNMVLKAAIELDLFELIAKSSAQKLSSYEIASQIPTKNPNAPLVLERVLRFLASQSFLTCNIIKDDDGNNHTSYKLTPLSQRFIPDKDGSSITPFLLLNADPVSVNSCFHLKDAILLGEVPFNMAHGMPAIEHAGKDSRLNMLFNKAMQNLTCIEMKRILECYNGFQGAKEVIDVGGGLGMSLASIISKHPNIKGINFDLPYVIKDAPTYEGMEHVGGDMFKSVPQGEVIILKEVLHNWDDENCVKILKNCWRALPKDGKIVIIEQIQPEYPEMNLLCKHSFSMDIAMMTIFDGGKERTKQQFEALAKQAGFTTTLKIVARAYYSWVMELYKY
>rna-XM_016689990.1
MGSTSNIQLPTQSEEERNCTYAMQLLSSSVLPFVLHSTIQLDVFEILAKDKTTKLSALEIVSHIPDCKNPDAATMLDRMLYVLASYSLLDCSVIEEKNGAMKRVYGLSGVGKFFVRNEDGASMGPLLALLQDKVFIHSWFELKDAVLEGAVPFDRVHGVHAFEYPKLDPKFNDVFNKAMINHTTIIMKRILENYKGFESLKSLVDVGGGLGVNLKMITSKYPTIKGINFDLPHVVQHAPSYPGVENVGGDMFESVPEGDAIFMKWILHDWSDSHCLKLLKNCYKALPDNGKVIVVEANLPVQPDTDTTVVGVSQCDLIMMAQNPGGKERSEQEFRALATEAGFKGVNLICCVCNFWVMEFHK
>rna-XM_016687647.1
MENGNGEISNTNDKARLAIMDLAHMMSVPMSLNAVVKLKLADAIWQGGSNAPLTSAEILAKIRGPKGGGDAENLQRVLRLLTSYDVFEEHTTDDGFQRRYSLTEVGKTLVTDEDGLSHGSYVLQHHQDAILRTWPMVHEVINDSSSEPFLKANGEKPYNYYGNNPELNSLMLNAMSGVSVPFMKGMLERYDGFQEVKTLVDVGGSGGDCLKMILEKHSSIQLGINFDLPEVVKKAPQIPRIKHVGGDIFDYIPKGDAIFMKWMLPIWTDDECKQIMKNCYDALPKKGKLIACEPVVPNHTDDSQRTRALLGGDIFIMSIYRAKGKHRTEEEFRQLGQAVGFSDCRTFYGDHYFTILEFHKL
>rna-XM_016687649.1
MEKASGKTSNNNNARLAIMELANMISVPMSLNAVVKLKVADAIWEVGSNTPLSPAEILAKIRGPQGGGDSENLQRILRMLMSYGVFEEHVVDDVSQRRYSLAEVGKSLVTDVDSLSHGSYVLQHHQDALMRAWTMVHEAVNDSSTEPFVKANGEPAYNYYGKNPEMNSIMLNAMSGVSVPFMKAILEGYDGFQGVKTLVDVGGSGGDCLKMILEKHSSIQLGINFDLPEVVEKAPQIPRVKHIGGDMFNSIPKGDAIFMKWVLTTWTDDECKQIMKSCYNALPEKGKFIACEPVLPHHTDDSKRTRALLEGDIFVMTIYRAKGKHRTEEEYRQLGRSAGFADCRGFYIDHFFTTLEFQKL
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University