Enzyme
The enzyme catalyses the biosynthesis of pterostilbene from resveratrol.
ROMT
Enzyme
Trans-resveratrol di-O-methyltransferase
Enzyme name
EC:2.1.1.240
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:trans-resveratrol 3,5-O-dimethyltransferase
Sysname
2 S-adenosyl-L-methionine + trans-resveratrol = 2 S-adenosyl-L-homocysteine + pterostilbene (overall reaction) [RN:R09872];(1a) S-adenosyl-L-methionine + trans-resveratrol = S-adenosyl-L-homocysteine + 3-methoxy-4',5-dihydroxy-trans-stilbene [RN:R09870];(1b) S-adenosyl-L-methionine + 3-methoxy-4',5-dihydroxy-trans-stilbene = S-adenosyl-L-homocysteine + pterostilbene [RN:R09871]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];pterostilbene [CPD:C10287];3-methoxy-4',5-dihydroxy-trans-stilbene [CPD:C20154]
Product
Species information
Capsicum annuum
Species name
Capsicum annuum is a species of eudicot in the family Solanaceae (nightshade family).
Species info
Gene sequence info
Capsicum_annuum.ROMT.fa
Download
>rna-XM_016701561.1
MTTIQGPSKTSSLDMSKHESTSTELLHAQAQIWNHIFNFISSSAVRCALQLGIPDALYKHGKPMSLDELSAGLSVVNSSKVSFLAILMRFLVQSGFLNQHEDQYFLTPASRLLAKNEPFNVRSVLLLNHGPAFSKAWSELSAWFQNDSPTAFHNAHGKIFWDYIEEEEPRVLGDIFNDALSSDSRFNTSLLITECKHVFEGLTSLVDVGGGTGTVSIAIAKAFPYLKCAVLELPHVIGHCKGSGNLDFVGGDMFDKIPHANAILLKAILHDWKGKDCVKILKKCKESIPSREKGGKVIIIDTEQ
>rna-XM_016693187.1
MSTSESASELLQAQAQIWNHIFSFISSSALRCAVELDIPDVLYKHGKPMHLSDLSAELSLVDPSKVTFLPNLIRFLVHSGLLNQHDDDCYSLTPASRFLVKNEPLNLRSLLVFTHDPFIQKAWFELGNWYKNDFPTTFHTAHEKSFWDYIVEEPRLGDTFNGLMASESRLIVTVLITECRHIFEGLTSLVDVGGGTGTVATAIAKAFPAIKCTVLDLPHVIENLKSSTGNLEFVGGNMFENIPTANAILLKWIMHDWNDEDCVKILKKCKDSIPSRDKGGKLIIIDIVLEDPKNTTEYARAQHNMDIMMLVCFAAKERTKKEWENLFNEAGFSECKITSIPGSRSLIEVYP
>rna-XM_016712245.1
MALPSDNIEDKSREVMAAQAHIWNHTFNFINSMSLKCAIQLGIPDIIHSHGRPMSLSDIVDALPINNNNARTQDCVYRLMRILIHAGFFIQEDEGYLLTPTSRLLLKDEPLSLAPLVQMELDPNLMDPWHSLSKWLKNGDDSSTPYATTHGMPIFEYAGNEPWLNHLFNEAMASDARLVMSVLTKSGKGVFKGLKSLVDVGGGTGTVARAIADAFPQINCTVLDLPHVIEGLEGCKNLSFVGGDMFKSIPSADAILIKWVLHNWSDEECIKILKKCKESIPSKENGGKVIIIDMVLMDQNLRTRDDKSYETQLFFDMLMMVAVSGKQRSQQDWANLFSHVGFSDYNIIPILGLRSVIEVYP
>rna-XM_016708574.1
MSKSDVELLNKNNVGDEAHSELLAAQAHIWNHAFSYINSMSLKCAIQLGIPDIIHNHGRAMTLSDLVNALPIDDKNKGLDCVYRLMRILTHAGFFIKTNKDINELDQENISYMLTSTSRLLLKDEPLSMIPYLQAQFDPILMGPWHYLSQWFQNGESSTTFAIAHGKPFFEYLEKEPKLNRVFNESMASDARLVISIVIENCKGVFEGLKSLVDLGGGTGTVAKFIANAFPQINCTVLDLPHVVEGCEGSKNLIYVGGDMFKFIPPADVILLESILHDWSDDYCIKILKKCKEAIPSKENGGKLIVIEIVMDHNRDHKSYETQLFLDMLMMVGVNGKERSQQEWAKIFSIAGFSDHNIIPILGLRCVIEVYP
>rna-XM_016712249.1
MALSNTNVGDETSEVLAAQAHIANHVLNYVNSMSLKCATQLGIPDIIHSHGRAMPLSDLIDALPINKAKGQECIYRLMRILIHAGFFIQEEEGYSLTPTSRLLLKDEPLSLAPFVLSQLDPLLVDPWQSLGEWFKNEDSTPFATAHGKPLFEYAGDEPRLNRLFNESMASDARLITSVLIKNGKGIFEGLKSVVDVGGGTGAVGKAISNAFPELKYAVFDLPHVVEGLEGSNNLSYIGGDMFKSVPSTDAIFLKWILHDWSDEDCVKILKKCKEAIPSKENGGKLIVIDIVIDNKNRDDKSFETQLFSDVLMMVHVSGKERSEQEWAKLFSDVGFSDYKISPILGLRSVIEVYP
>rna-XM_016721720.1
MCYSTWNSRYYPLSWPGHDSIQFGFLSQTQVNDKEEEGYLLTPASRLLLKDEPLCQIPFVQMELEPHFMDPWHSLSQWIKNGNDSSTPFAICHVKPLFEYDEKKPKINRQFNEIMASDSRLIMSVVIEHCKAVFEGLKSLVDVGGCPGIVAKIIANALPEIDCIVFDLPHVIEGCEGSKNLSYVEGDMFKSIPSIDEILLKWVLHDWGDEGCIKILKECKEAIPSKEKGGKVIIIDMVLTDHKLQKGDDKSYETQLFFDMLMMVHVSGKERNQQDWAKLFSGAGFGDYNIIPVLGLRSIIEVFPLSVEFAKLNKTPVK
>rna-XM_016690125.1
MVVPIVGEHETEILHAQTHIWNHIFSFINSMSLKSAIQLNIPDILHKHGKPMTLDELVNAISINKSKTTHLRRLMRILIHSGFFLKSPINPDQGPEGGEGYVLAPPARLLLKDEPLSVTPFLLAMLDPILVKPWHHVSEWFESDEPTPFEVAHGRTFWDYAGHEPRLNHFFNDAMASDAKLVMSVVMKYSKDVFEGLNTIVDVGGGTGTVAKTIAKNFPNLKCTVFDLPHVVEGLEPSDNLTYVGGDFFVSIPPADALLLKWILHDWSDEESVKILKKCKEAIPSKEKGGKVIIIDMMVDNKIADDESIETQIFFDMLMMVLVTGRERTEKGWSKIFFEAGFSDYKVTPILGLRSLIEVYP
>rna-XM_016689417.1
MADHNDQNLTPSELLLAETQSWNQLYFFIEHVTLKCAFQLGIPNAITKHGKPMTLSKLMSSLSISPSKYPYFHRLTRILVHYGLLILQKHEDNNVDDGDDSKGYYSLAPTDRYIMKDGPWNSMEDQDSFFFKAWNCLGDWFRNEDPSAFYTAYGDLFWSKLSRDTSSGNWFHANMARDSRSFMNVLIGNEFKDVFKGLTSLVDVGGGTGTVAMAITKKFPDMKCIVLDLPPVVANLQGSENLEFVAGDMFQKIPAANAVLLKSILHDWNDEECVKILKNCKDAITRSGKVIIIDMVMENPELDDESFQAQLFIDMLMMVFLGSKERNKKEWEKLFFDAGFTSYKIILTLGLRSVIELYP
>rna-XM_016691176.1
MALYNKIGEDASQIPAAQGYIWNHIFNYINSMSLKCAIQLGIPDIIHSHGRAMTLSDLVNSLPINNINSTIRNCIYRLMRILIHAGFFIQTNLVNKEEKTEEEEEEGGYLPTPASRLLLKDDPLSLVPLVQVGLDSLMMDPWQYLSMWFEKGDHSSTTPFVIAHGKPFFEYVGNEPRLNHLFNEAMANDSRLSISVIIEHCKEIFEGLKSLVDIGGGTGTMAKSIADMFPQINCIVLDLPHVIEGCEGSKNLSYVGGDMFKFIPSADAILLKLILHDWSDEDCIKILKKCKQAIPSKENGGRVIIIDMVLMDQKGDHNAYETQLFFDMLMMVYSFGRERSQQEWAKLFFDSGFSDYKIIPILGLRSIIEIYP
>rna-XM_016691014.1
MRYYGTDHIWNHTFNFINSMSLKCAIQLGIPDIIHNHGQPMTLSDLVKSLPISNINGKTRNCIYRLMRILFHAGFFAEEKEEEKEEEGYLLTPTSRLFLKNEPLSLVPFLQVQLDPMMMDPWQCLGKWFKNGDHSSSTTPFGAVHGKPFFEYSVDEPRFNRLFNESMSCDAALVTSVITEYCKGAFEGLKSLVDIGGGTGTLAKAIVDTFPQISCTVFDLPQVIEGCEGSKNITYVSGDMFKFNPSVDVIFLKGILHDWSDEDCIKILKKCEKAISIKENGARVIIIDMVLMGQKGDHNAYETKLFMDVLMMVHPFGKERSQQEWAKLFSDSGFSFSDYKIIPILVLRSIIEIYP
>rna-XM_016699780.1
MSTSENSSTELLHAQAQIWNYIFNFVNSSAVSCALQLGILDILYKHGKPMCLDDLSTELSVVNPSKISFLLILMRFLVQSGFLNQHEDHFSLTPASRLLAKNEPFNVRSLLLLNHGPVFSKAWPELSAWFQNDSPTPFHAAHEKSLWDYIEEEEPRVLGDIFNDALASDSRLNTNVLITECKHVFEGLTSLVDVGGGTGTVSMPIAKAFPNIKCTVLDLPHVIGDLKGGGNLEFVAGDMFDQIPHANAILLKCVLHDWMDEDCVKILKKCKESIPSREKRGKVIIIDTVLDDPKKSNEFVRAQHNMDMLMMVLYAAKERTKKEWEKLFIESGFTEYKIVPALGLRSLIEIYP
MTTIQGPSKTSSLDMSKHESTSTELLHAQAQIWNHIFNFISSSAVRCALQLGIPDALYKHGKPMSLDELSAGLSVVNSSKVSFLAILMRFLVQSGFLNQHEDQYFLTPASRLLAKNEPFNVRSVLLLNHGPAFSKAWSELSAWFQNDSPTAFHNAHGKIFWDYIEEEEPRVLGDIFNDALSSDSRFNTSLLITECKHVFEGLTSLVDVGGGTGTVSIAIAKAFPYLKCAVLELPHVIGHCKGSGNLDFVGGDMFDKIPHANAILLKAILHDWKGKDCVKILKKCKESIPSREKGGKVIIIDTEQ
>rna-XM_016693187.1
MSTSESASELLQAQAQIWNHIFSFISSSALRCAVELDIPDVLYKHGKPMHLSDLSAELSLVDPSKVTFLPNLIRFLVHSGLLNQHDDDCYSLTPASRFLVKNEPLNLRSLLVFTHDPFIQKAWFELGNWYKNDFPTTFHTAHEKSFWDYIVEEPRLGDTFNGLMASESRLIVTVLITECRHIFEGLTSLVDVGGGTGTVATAIAKAFPAIKCTVLDLPHVIENLKSSTGNLEFVGGNMFENIPTANAILLKWIMHDWNDEDCVKILKKCKDSIPSRDKGGKLIIIDIVLEDPKNTTEYARAQHNMDIMMLVCFAAKERTKKEWENLFNEAGFSECKITSIPGSRSLIEVYP
>rna-XM_016712245.1
MALPSDNIEDKSREVMAAQAHIWNHTFNFINSMSLKCAIQLGIPDIIHSHGRPMSLSDIVDALPINNNNARTQDCVYRLMRILIHAGFFIQEDEGYLLTPTSRLLLKDEPLSLAPLVQMELDPNLMDPWHSLSKWLKNGDDSSTPYATTHGMPIFEYAGNEPWLNHLFNEAMASDARLVMSVLTKSGKGVFKGLKSLVDVGGGTGTVARAIADAFPQINCTVLDLPHVIEGLEGCKNLSFVGGDMFKSIPSADAILIKWVLHNWSDEECIKILKKCKESIPSKENGGKVIIIDMVLMDQNLRTRDDKSYETQLFFDMLMMVAVSGKQRSQQDWANLFSHVGFSDYNIIPILGLRSVIEVYP
>rna-XM_016708574.1
MSKSDVELLNKNNVGDEAHSELLAAQAHIWNHAFSYINSMSLKCAIQLGIPDIIHNHGRAMTLSDLVNALPIDDKNKGLDCVYRLMRILTHAGFFIKTNKDINELDQENISYMLTSTSRLLLKDEPLSMIPYLQAQFDPILMGPWHYLSQWFQNGESSTTFAIAHGKPFFEYLEKEPKLNRVFNESMASDARLVISIVIENCKGVFEGLKSLVDLGGGTGTVAKFIANAFPQINCTVLDLPHVVEGCEGSKNLIYVGGDMFKFIPPADVILLESILHDWSDDYCIKILKKCKEAIPSKENGGKLIVIEIVMDHNRDHKSYETQLFLDMLMMVGVNGKERSQQEWAKIFSIAGFSDHNIIPILGLRCVIEVYP
>rna-XM_016712249.1
MALSNTNVGDETSEVLAAQAHIANHVLNYVNSMSLKCATQLGIPDIIHSHGRAMPLSDLIDALPINKAKGQECIYRLMRILIHAGFFIQEEEGYSLTPTSRLLLKDEPLSLAPFVLSQLDPLLVDPWQSLGEWFKNEDSTPFATAHGKPLFEYAGDEPRLNRLFNESMASDARLITSVLIKNGKGIFEGLKSVVDVGGGTGAVGKAISNAFPELKYAVFDLPHVVEGLEGSNNLSYIGGDMFKSVPSTDAIFLKWILHDWSDEDCVKILKKCKEAIPSKENGGKLIVIDIVIDNKNRDDKSFETQLFSDVLMMVHVSGKERSEQEWAKLFSDVGFSDYKISPILGLRSVIEVYP
>rna-XM_016721720.1
MCYSTWNSRYYPLSWPGHDSIQFGFLSQTQVNDKEEEGYLLTPASRLLLKDEPLCQIPFVQMELEPHFMDPWHSLSQWIKNGNDSSTPFAICHVKPLFEYDEKKPKINRQFNEIMASDSRLIMSVVIEHCKAVFEGLKSLVDVGGCPGIVAKIIANALPEIDCIVFDLPHVIEGCEGSKNLSYVEGDMFKSIPSIDEILLKWVLHDWGDEGCIKILKECKEAIPSKEKGGKVIIIDMVLTDHKLQKGDDKSYETQLFFDMLMMVHVSGKERNQQDWAKLFSGAGFGDYNIIPVLGLRSIIEVFPLSVEFAKLNKTPVK
>rna-XM_016690125.1
MVVPIVGEHETEILHAQTHIWNHIFSFINSMSLKSAIQLNIPDILHKHGKPMTLDELVNAISINKSKTTHLRRLMRILIHSGFFLKSPINPDQGPEGGEGYVLAPPARLLLKDEPLSVTPFLLAMLDPILVKPWHHVSEWFESDEPTPFEVAHGRTFWDYAGHEPRLNHFFNDAMASDAKLVMSVVMKYSKDVFEGLNTIVDVGGGTGTVAKTIAKNFPNLKCTVFDLPHVVEGLEPSDNLTYVGGDFFVSIPPADALLLKWILHDWSDEESVKILKKCKEAIPSKEKGGKVIIIDMMVDNKIADDESIETQIFFDMLMMVLVTGRERTEKGWSKIFFEAGFSDYKVTPILGLRSLIEVYP
>rna-XM_016689417.1
MADHNDQNLTPSELLLAETQSWNQLYFFIEHVTLKCAFQLGIPNAITKHGKPMTLSKLMSSLSISPSKYPYFHRLTRILVHYGLLILQKHEDNNVDDGDDSKGYYSLAPTDRYIMKDGPWNSMEDQDSFFFKAWNCLGDWFRNEDPSAFYTAYGDLFWSKLSRDTSSGNWFHANMARDSRSFMNVLIGNEFKDVFKGLTSLVDVGGGTGTVAMAITKKFPDMKCIVLDLPPVVANLQGSENLEFVAGDMFQKIPAANAVLLKSILHDWNDEECVKILKNCKDAITRSGKVIIIDMVMENPELDDESFQAQLFIDMLMMVFLGSKERNKKEWEKLFFDAGFTSYKIILTLGLRSVIELYP
>rna-XM_016691176.1
MALYNKIGEDASQIPAAQGYIWNHIFNYINSMSLKCAIQLGIPDIIHSHGRAMTLSDLVNSLPINNINSTIRNCIYRLMRILIHAGFFIQTNLVNKEEKTEEEEEEGGYLPTPASRLLLKDDPLSLVPLVQVGLDSLMMDPWQYLSMWFEKGDHSSTTPFVIAHGKPFFEYVGNEPRLNHLFNEAMANDSRLSISVIIEHCKEIFEGLKSLVDIGGGTGTMAKSIADMFPQINCIVLDLPHVIEGCEGSKNLSYVGGDMFKFIPSADAILLKLILHDWSDEDCIKILKKCKQAIPSKENGGRVIIIDMVLMDQKGDHNAYETQLFFDMLMMVYSFGRERSQQEWAKLFFDSGFSDYKIIPILGLRSIIEIYP
>rna-XM_016691014.1
MRYYGTDHIWNHTFNFINSMSLKCAIQLGIPDIIHNHGQPMTLSDLVKSLPISNINGKTRNCIYRLMRILFHAGFFAEEKEEEKEEEGYLLTPTSRLFLKNEPLSLVPFLQVQLDPMMMDPWQCLGKWFKNGDHSSSTTPFGAVHGKPFFEYSVDEPRFNRLFNESMSCDAALVTSVITEYCKGAFEGLKSLVDIGGGTGTLAKAIVDTFPQISCTVFDLPQVIEGCEGSKNITYVSGDMFKFNPSVDVIFLKGILHDWSDEDCIKILKKCEKAISIKENGARVIIIDMVLMGQKGDHNAYETKLFMDVLMMVHPFGKERSQQEWAKLFSDSGFSFSDYKIIPILVLRSIIEIYP
>rna-XM_016699780.1
MSTSENSSTELLHAQAQIWNYIFNFVNSSAVSCALQLGILDILYKHGKPMCLDDLSTELSVVNPSKISFLLILMRFLVQSGFLNQHEDHFSLTPASRLLAKNEPFNVRSLLLLNHGPVFSKAWPELSAWFQNDSPTPFHAAHEKSLWDYIEEEEPRVLGDIFNDALASDSRLNTNVLITECKHVFEGLTSLVDVGGGTGTVSMPIAKAFPNIKCTVLDLPHVIGDLKGGGNLEFVAGDMFDQIPHANAILLKCVLHDWMDEDCVKILKKCKESIPSREKRGKVIIIDTVLDDPKKSNEFVRAQHNMDMLMMVLYAAKERTKKEWEKLFIESGFTEYKIVPALGLRSLIEIYP
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University