Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Capsicum annuum
Species name
Capsicum annuum is a species of eudicot in the family Solanaceae (nightshade family).
Species info
Gene sequence info
Capsicum_annuum.CHS.fa
Download
>rna-XM_016702139.1
MSENNKNVDGATNHFFQPSRRLPTPGKATILAMGKAFPSQLVPQDCLVEGYMRDTNCQDMAIKEKLERLCKTTTVKTRYTVMSKEILDKYPELAVEGTPTINQRLEIANPAVVEMAKQASLACIKEWGRSTDEITHIVYVSSSEIRLPGGDLHLATELGLRSDIGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNNARPYDLVGAALFGDGAGAVIVGTEPIVGTESPFMELNFALQQFLPGTKNVIDGRLTEEGINFKLGRDLPEKIQDNIEEFCKKLIEKGDQLKETKYNDLFWAVHPGGPAILDRLERTLKLQSGKLDCSRRALMDYGNVSSNTIFYVIEYMRQELQNKKDGGEEWGLALAFGPGITFEGILLRSL
>rna-XM_016710598.1
MVTVEEYRKAQRAEGPATVMAIGTATPSNCVDQSTYPDYYFRITNSEHKTELKEKFKRMCEKSMIKTRYMHLTEEILKENPNMCAYMAPSLDARQDIVVVEVPKLGKEAAQKAIKEWGQPKSKITHLVFCTTSGVDMPGCDYQLAKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSESHLDSLVGQALFGDGAAAIIMGSDPIPGVERPLFQLVSAAQTLLPDSEGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFQPLGISDWNSLFWIAHPGGPAILDQVELKLGLKPEKLKATREVLSNYGNMSSACVLFILDEMRKASTKEGLGTSGEGLEWGVLFGFGPGLTVETVVLHSVAI
>rna-XM_016718115.1
MKLENGQKIMRVHERAEGPAKILAIGIATPFHWVDQTAYPDYYFKVTNSEHFVDLKEKFRRICSRTMIRKRHMILTEEILKKNPNLCSYNGPSLDIRQEILVSEIPKLGKEAALMAIDEWAQPKSKITHLVFCTRSGVDMPGADYQLIKLLGLSPSVQRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSESSAIGFRGPSEAHPENLIAQALFGDGAAAVIIGSDPKPGLERPVFEIVTATQSFVPNGDCHLALHLREMGLTFHCTKDVPPTIAKNVESCLIKAFEPLGISDWNSMFWILHPGGNAIVEQVESTLGLEPEKLRATRNILREYGNLSSACVLFILDEIRKKSARDGLKTSGDGLDLGVLLSFGPGLTIETVVLRSQPI
>rna-XM_016718139.1
MVTVEEVRREQRAKGPATIMAIGTATPSNCVDQATYPDYYFRITNSEHMTELKEKFQRMCDKSMIKKRYMHLTEEILKENPNICEYMAPSLDARQDIVVVEIPKLGKEAAKKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVIRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSMVGQALFGDGAAALIVGSDPLPEVERPLFELVSAAQTLLPDSEGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLIEAFQPLGISDWNSIFWIAHPGGPAILDQVELKLGLKLEKLRATRQVLSDYGNMSSACVLFILDEMRKASAKEGLNTTGEGLDWGVLFGFGPGLTVETVVLHSVSTNLEHPRVQEKEFE
>rna-XM_016726963.1
MVTVEEVRRAERAMGPATILAIGTATPLNCVNQSTYPDYFFRVTKSEHKTELKEKFKRMCDASMIKKRYLHLTEEILKENPSICEHMEPSFDTRQNIVIVEIPKLGQEASQKAINEWGQSKFKITHLIFCTTSGVDMPGADYQLTKLLELSPSIKRFMLYQQGCYGGGAALRLAKDLAENNKDARVLVVCAEIAVQTFHGPSDTELEGLVGQVLFADGAAAVIIGSDPILEVERSLFELVYATQTLLPNTGYAVYGTTLLLEKLG
>rna-XM_016726955.1
MGRLEKMEGKKEINSGNATILALGKAFPHQLVMQEFLVDGYFKNTNCDDPELKQRLTRLCKTTTVKTRYVVMSEEILKKYPELAVEGLPTVKQRLDICNAAVTEMAIEASKSCINKWGRPLSDITHVVYVSSSEARLPGGDLYLAKGLGLSPDTKRVTLYFAGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSVDRPYDLVGVALFGDGAGAMIIGSNPIRDIERPLFELHTAIQHFLPDTEKIIDGRLTEEGISFKLERELPQIIEDNIEDFCDKLISNYTGINDREYNKLFWAVHPGGPAILNRLEKKLELSPDKLSASRRALADYGNASSNTIVYVLEYMLEEKSDNNKQDSDWGLILAFGPGITFEGILTKNLTSY
>rna-XM_016694194.1
MVTVEEILRVQRAEGAAAVLAIGTATPHNGVDQSTYPDYFFRVTNNEHKTERMCDGSVIKKRYIHLTEEILKENPNICEHNAPSFNARQDIVVVEVPKLGKEAAQKAINEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLSPSVKRFMMYQQGCSGGGAVLRLAKDLAENNKGARVLVVCSEILAITFHGPSDTEVDVLIGQVLFGDGAAAVIIGSDPNLEVERPLFELVFATQTLLPDTGYAVYGKTSEAGLKFHLHKNVPRLISNDIEKSLVEIFEPLGISDWNSIFWVVHAGGRAIMDKVESKLGLKPEKLRATRHVLREYGNVASACVLFVLDEIRKNSIKEGLDTTGEGLEWGVLFGFGPGLTIETLVLRSVSNIHK
>rna-XM_016696552.1
MVTVEEVRRAQRAEGPATVLAIGTATPLNCVDQSTYPDYFFRVTNSEHQTDLKEKFKRMCNGSMIEKRYMHLTEEILKENPSICEHKAPSLGARQEIAIVEVPKLGKEAAQKAIEEWGQPISKITHLVFCTTTGVDMPGADCRLAELLGLSPSIKRFMMYQQGCYGGGVVLRLAKDLAENNKCARVLAVCAEITVATFHGPSDTDLDVLVGQALFGDGAGAIIIGSDPIAEVERPLFELVSATQTLIPDTRYAVYGNTSEVGLTVHLHKDVSKLISNNIEKSLTEIFEPLDIFDWNSIFWVVHAGGRAILDQIELKLGLKPEILKATRNVLSEYGNIASACVLFVLDEMRKGSINEGLEWGVLVGFGPGLTIETIVLHNVDKIHK
>rna-XM_016695870.1
MVTVNEIRRAQRAEGPATVLAIGIANPTNCYDQSTYADYFFRVTNSEHKTELMEKFKRMCDGSMIKKRYFHLTEDILKKNPELCEYKAPSFNVRQEIAIVEVPKLAKEAAQKAINEWGQSTSKISHLVFCTTSGVDIPGADYQLTKLLGLGASVKRFMMYQQGCFGGGTALRLAKDLAENNKGARVLAMCSELINLLCFHAPNETESEVMVGQALFSDGASAVIVGSDPIVEVERPLFELVFATQTLLPNSGHAITGDLNEAGLIAQIHKDTPTLISENIERILVDAFGSLGISDWNSIFWVSHAGGRAILHQIELKLNLKPEKLRATRNVMSNYGNMGSACVLFVLDEMRKASIKEGLGTTGEGLEWGVLFGFGPGLTIEAIVLRSVSV
>rna-XM_016695871.1
MVTINGIPAQRAVGPATILSIGTANPPNCFDQSTYADYFFRVTNSEHKAELKEKFKRMCERSMIKKRYFHLTEEILKKNPNICKYKAPSLDARQQIAIVQVPKLGKEAAQKAIKEWGQSKDEITHLVFCTTSGVDVPGADYQLTKLLGLSPSVKRFMIYQQGCTGGATVVRLAKDLAENNKGARVLAVCSEISMFCFHAPSETETDVLIGQALFSDGASAIIVGSDPVLTMERPLFQIVSATQTLLPDSGHAIIGSLTEAGLIAKIHKDTPMLISKNIERILVEAFQPLGISDWNSIFWVSHAGGRAILDQIELELGLKPEKLRATRNVMSDYGNMGSVSVLFVLDEMRKVSIKAELGTTGEGHVCWGVLLGFGPGLTIEAVVLRSLSV
MSENNKNVDGATNHFFQPSRRLPTPGKATILAMGKAFPSQLVPQDCLVEGYMRDTNCQDMAIKEKLERLCKTTTVKTRYTVMSKEILDKYPELAVEGTPTINQRLEIANPAVVEMAKQASLACIKEWGRSTDEITHIVYVSSSEIRLPGGDLHLATELGLRSDIGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNNARPYDLVGAALFGDGAGAVIVGTEPIVGTESPFMELNFALQQFLPGTKNVIDGRLTEEGINFKLGRDLPEKIQDNIEEFCKKLIEKGDQLKETKYNDLFWAVHPGGPAILDRLERTLKLQSGKLDCSRRALMDYGNVSSNTIFYVIEYMRQELQNKKDGGEEWGLALAFGPGITFEGILLRSL
>rna-XM_016710598.1
MVTVEEYRKAQRAEGPATVMAIGTATPSNCVDQSTYPDYYFRITNSEHKTELKEKFKRMCEKSMIKTRYMHLTEEILKENPNMCAYMAPSLDARQDIVVVEVPKLGKEAAQKAIKEWGQPKSKITHLVFCTTSGVDMPGCDYQLAKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSESHLDSLVGQALFGDGAAAIIMGSDPIPGVERPLFQLVSAAQTLLPDSEGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFQPLGISDWNSLFWIAHPGGPAILDQVELKLGLKPEKLKATREVLSNYGNMSSACVLFILDEMRKASTKEGLGTSGEGLEWGVLFGFGPGLTVETVVLHSVAI
>rna-XM_016718115.1
MKLENGQKIMRVHERAEGPAKILAIGIATPFHWVDQTAYPDYYFKVTNSEHFVDLKEKFRRICSRTMIRKRHMILTEEILKKNPNLCSYNGPSLDIRQEILVSEIPKLGKEAALMAIDEWAQPKSKITHLVFCTRSGVDMPGADYQLIKLLGLSPSVQRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSESSAIGFRGPSEAHPENLIAQALFGDGAAAVIIGSDPKPGLERPVFEIVTATQSFVPNGDCHLALHLREMGLTFHCTKDVPPTIAKNVESCLIKAFEPLGISDWNSMFWILHPGGNAIVEQVESTLGLEPEKLRATRNILREYGNLSSACVLFILDEIRKKSARDGLKTSGDGLDLGVLLSFGPGLTIETVVLRSQPI
>rna-XM_016718139.1
MVTVEEVRREQRAKGPATIMAIGTATPSNCVDQATYPDYYFRITNSEHMTELKEKFQRMCDKSMIKKRYMHLTEEILKENPNICEYMAPSLDARQDIVVVEIPKLGKEAAKKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVIRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSMVGQALFGDGAAALIVGSDPLPEVERPLFELVSAAQTLLPDSEGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLIEAFQPLGISDWNSIFWIAHPGGPAILDQVELKLGLKLEKLRATRQVLSDYGNMSSACVLFILDEMRKASAKEGLNTTGEGLDWGVLFGFGPGLTVETVVLHSVSTNLEHPRVQEKEFE
>rna-XM_016726963.1
MVTVEEVRRAERAMGPATILAIGTATPLNCVNQSTYPDYFFRVTKSEHKTELKEKFKRMCDASMIKKRYLHLTEEILKENPSICEHMEPSFDTRQNIVIVEIPKLGQEASQKAINEWGQSKFKITHLIFCTTSGVDMPGADYQLTKLLELSPSIKRFMLYQQGCYGGGAALRLAKDLAENNKDARVLVVCAEIAVQTFHGPSDTELEGLVGQVLFADGAAAVIIGSDPILEVERSLFELVYATQTLLPNTGYAVYGTTLLLEKLG
>rna-XM_016726955.1
MGRLEKMEGKKEINSGNATILALGKAFPHQLVMQEFLVDGYFKNTNCDDPELKQRLTRLCKTTTVKTRYVVMSEEILKKYPELAVEGLPTVKQRLDICNAAVTEMAIEASKSCINKWGRPLSDITHVVYVSSSEARLPGGDLYLAKGLGLSPDTKRVTLYFAGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSVDRPYDLVGVALFGDGAGAMIIGSNPIRDIERPLFELHTAIQHFLPDTEKIIDGRLTEEGISFKLERELPQIIEDNIEDFCDKLISNYTGINDREYNKLFWAVHPGGPAILNRLEKKLELSPDKLSASRRALADYGNASSNTIVYVLEYMLEEKSDNNKQDSDWGLILAFGPGITFEGILTKNLTSY
>rna-XM_016694194.1
MVTVEEILRVQRAEGAAAVLAIGTATPHNGVDQSTYPDYFFRVTNNEHKTERMCDGSVIKKRYIHLTEEILKENPNICEHNAPSFNARQDIVVVEVPKLGKEAAQKAINEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLSPSVKRFMMYQQGCSGGGAVLRLAKDLAENNKGARVLVVCSEILAITFHGPSDTEVDVLIGQVLFGDGAAAVIIGSDPNLEVERPLFELVFATQTLLPDTGYAVYGKTSEAGLKFHLHKNVPRLISNDIEKSLVEIFEPLGISDWNSIFWVVHAGGRAIMDKVESKLGLKPEKLRATRHVLREYGNVASACVLFVLDEIRKNSIKEGLDTTGEGLEWGVLFGFGPGLTIETLVLRSVSNIHK
>rna-XM_016696552.1
MVTVEEVRRAQRAEGPATVLAIGTATPLNCVDQSTYPDYFFRVTNSEHQTDLKEKFKRMCNGSMIEKRYMHLTEEILKENPSICEHKAPSLGARQEIAIVEVPKLGKEAAQKAIEEWGQPISKITHLVFCTTTGVDMPGADCRLAELLGLSPSIKRFMMYQQGCYGGGVVLRLAKDLAENNKCARVLAVCAEITVATFHGPSDTDLDVLVGQALFGDGAGAIIIGSDPIAEVERPLFELVSATQTLIPDTRYAVYGNTSEVGLTVHLHKDVSKLISNNIEKSLTEIFEPLDIFDWNSIFWVVHAGGRAILDQIELKLGLKPEILKATRNVLSEYGNIASACVLFVLDEMRKGSINEGLEWGVLVGFGPGLTIETIVLHNVDKIHK
>rna-XM_016695870.1
MVTVNEIRRAQRAEGPATVLAIGIANPTNCYDQSTYADYFFRVTNSEHKTELMEKFKRMCDGSMIKKRYFHLTEDILKKNPELCEYKAPSFNVRQEIAIVEVPKLAKEAAQKAINEWGQSTSKISHLVFCTTSGVDIPGADYQLTKLLGLGASVKRFMMYQQGCFGGGTALRLAKDLAENNKGARVLAMCSELINLLCFHAPNETESEVMVGQALFSDGASAVIVGSDPIVEVERPLFELVFATQTLLPNSGHAITGDLNEAGLIAQIHKDTPTLISENIERILVDAFGSLGISDWNSIFWVSHAGGRAILHQIELKLNLKPEKLRATRNVMSNYGNMGSACVLFVLDEMRKASIKEGLGTTGEGLEWGVLFGFGPGLTIEAIVLRSVSV
>rna-XM_016695871.1
MVTINGIPAQRAVGPATILSIGTANPPNCFDQSTYADYFFRVTNSEHKAELKEKFKRMCERSMIKKRYFHLTEEILKKNPNICKYKAPSLDARQQIAIVQVPKLGKEAAQKAIKEWGQSKDEITHLVFCTTSGVDVPGADYQLTKLLGLSPSVKRFMIYQQGCTGGATVVRLAKDLAENNKGARVLAVCSEISMFCFHAPSETETDVLIGQALFSDGASAIIVGSDPVLTMERPLFQIVSATQTLLPDSGHAIIGSLTEAGLIAKIHKDTPMLISKNIERILVEAFQPLGISDWNSIFWVSHAGGRAILDQIELELGLKPEKLRATRNVMSDYGNMGSVSVLFVLDEMRKVSIKAELGTTGEGHVCWGVLLGFGPGLTIEAVVLRSLSV
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University