Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Capsicum annuum
Species name
Capsicum annuum is a species of eudicot in the family Solanaceae (nightshade family).
Species info
Gene sequence info
Capsicum_annuum.4CL.fa
Download
>rna-XM_016705836.1
MGTHVAECTQQQEEGEHIFRSRYPPVDVPDNVTLPDFVLHNVELYADRLAFVDATTGKGYTYGEVARDIRRFAKALRSLGLRKGRVVLVVLPNVPEYAIVALGIMAAGGVFSGANPAAHSSEIMKQVESADGKLIVSDLPTYHKVKDCGLPVIILGEERVEGTIHWDELLEAADRASSRTDHITNQEDEIVQQSDLCALPFSSGTTGLSKGVMLTHRNLVANLCSTLFSISPEMVGQVTTLGLIPFFHIYGITGICCATIRNKGKVVVMRRYELRAFLNALITHEVTFAPIVPPIILALVKNPIVDEFDLKKLKLRSIMTAAAPLAPEILNEFEKKFPDVQVQEAYGMTEHSCITLSHSNQHIAKRNSVGFILPNLGVKFVDPDTGRSLPKNTPGEICVKSQCVMKGYYKNESETCLTIDKDGWLHTGDIGYIDDDGDIFLVDRIKELIKYKGFQVAPAELEGILLTHPSVEDAAVVGLPDEEAGEIPAAWVVLNSKAKESHEDIINFVASTAAHYKRVRVVQFVDSIPKSPSGKIMRRLIKEKMLEKLKEGRE
>rna-XM_016708649.1
MASVATVEAQKAEISSTVIPPSNQNQSSEELHVFRSRLPDIVISNDIPLHVYLFEKLSEFQERTCLIAGNTGQTFTFGETHFICQKIAAGLTNIGIKKGDVIMTFLQNCTEFVFTFLAASMIGSVITTANPFYTKSEAFKQLKASNAKLIVTQSQYVDKFRDPVENDPKINEDFLVVTIDDPPENCLHFSVLAEANADDMPKGVVIQPEDPVALPFSSGTTGLPKGVILTHKSLITGVAQLVDGDNPNLYLKHQDVVLCVLPLFHIFALNSVLLVSLRAGASVLLMQKFEIGTLLELIQKYRVSVAAVVPPLVLALAKNPMVDSFDLSSIRLVLSGAAPLGIWYDRGRTSSNNVSIICKATSFNQVRFMWVCGSKCGP*GGRPRNRWLP*PQPTR*NLHSRFSNHERLFE***GHCTNH*R*WMAPHWRYRIC**R**NIHRR*SQRTHQVQRFPGATS*A*VTSSKPSRYCRCCCCAAKG*CCRGSAGCICSPFGPRL*TY*RSYKGIYCQTGGVL*EIAQGVFYSCNSKVSIWKDTEERTESQTGCNSLL
>rna-XM_016707524.1
MPMENETRDLIFRSKLHDIYIPKHLPLHSYCFENISEFNSRPCLIDGANDQIYSYAEVELTSRKVAVGLNKLGVQQKDTIMILLPNSPEFVFAFMGASYLGAISTMANPLFTPAEVLKQAKASSAKIIITLACYIGKVKDYATENDVKLICIDSAPEGCIHFSELTQSDEHEIPDVKIQPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENANLYMHSEDVLMCCLPLFHIYSLNSVLLCGLRIGAAILIMQKFDIVHFLELIQKYKVTIGPFVPPIVLAIAKSPLVDHYDLSSVRTVMSGAAPLGKELEDTVRTKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPDTGCSLPRNQPGEICIRGDQIMKGYLNDLESTTRTIDKEGWLHTGDMGFIDNDDELFIVDRLKELIKYKGFQVAPAELEALLLNHPNISDAAVVPMKDEQAGEVPVAFVVRSNGSTITEDEVKDFVSKQVVFYKRIKRVFFVETVPKSPSGKILRKDLRARLAAGVTN
>rna-XM_016722940.1
MPMENEAKQGDIIFRSKLPDIYIPNHLSLHSYCFENISEFSSRPCLINGANNQIYTYADVELNSRKVAAGLHKQFGIQQKDTIMILLPNSPEFVFAFLGASYLGAISTMANPLFTPAEVVKQVKASNAEIIVTQACHVNKVKDYALENDVKIVCIDSAPEGCVHFSELIQADEHDIPEVQIKPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYIHSEDVMLCVLPLFHIYSLNSVLLCGLRVGAAILIMQKFDIVPFLELIQNYKVTIGPFVPPIVLAIAKSPMVDNYDLSSVRTVMSGAAPLGKELEDTVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPDTGNSLHRNQSGEICIRGDQIMKGYLNDPEATAGTIDKEGWLHTGDIGYIDNDDELFIVDRLKELIKYKGLLNHPNISDAAVVPMKDEQAGEVPVAFVVRSNGSTITEDEVKEFISKQVIFYKRIKRVFFVDAVPKSPSGKILRKDLRAKLAAGFPN
>rna-XM_016724135.1
MEMMNKLQNHDHDEFIFRSKLPNIYIPNHLPLHKYCFENISQFSSRTCLINSTTGATYSYIDVELIAKRIALGLHQLGIEQRDVIMLLLPNSPEFVFAFLGALFRGVICTTANPFYTPSEITKQAKASNAKLIITQSLYVDKIKRYAEENEVKIMCTDDDSTPDDCLSFAELLLNCQNDIHLSDSVKILPDDVAALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHSEDVIMCVLPMFHIYSLNSILLCGLRVGATILIMQKFEIKGLMELVEKYKVTIAPFVPPIVLAIAKSPLVDEYDLSSIRMIMSGAAPMGKELEDTVRAKLPNAILGQGYGMTEAGPVLSMCLAFAKQQFEVKSGSCGTVVRNAEMKIVDTNTGAFLPRNHAGEICIRGDQIMKGYLNNPKATEETIDKEGWLHTGDIGYIDDDDQVFIVDRLKELIKYKGYQVAAAELEAMLISNPNISDAAVVPMKDEVAGEVPVAFVVRANGSKISEDEIKQYVSQQVIFYKRINRVFFTEEIPKAPSGKILRKDLRAKLAAGGLAS
>rna-XM_016689754.1
MDPKQVGDTIFRSKLPDIYIPNHLPLHSYCFQNISEFSYRPCLINGSNDQIYTYADVELTSRKVAAGLNKLKIQQKDTIMILLPNSPEFVFSFLGASYVGAISTMANPMFTQAEVVKQAKASKAKLIITQECNLDKVKDYAFENDVKVICIDESSGDLPEGCLHFSNLILNSVFVSEHDPPEVEIQPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPTLYLHSEDVILCISPLFHIYSLVSILLCGLRVGAAILIMQKFDIVSFFELVEKYKVTIGPFVPPIVLAISKSPVVDNYDLSSVRRVMCGAAPLGKGLEDAVRTKFPHAKFGQGYGMTEAGAPMSMCLAFAKEPFEIKSGACGTVIRNAEMKIVDPDTGISLPRNKPGEICIRGDQIMKGYLNDPEATARTIDKEGWLHSGDIGYIDEDDELFIMDRLKELIKYKGFQVAPAELEALLLNLPDISDVAVIPMKDEEAGEVPVAFVVRSNGSTITEHEIKDFIYKQVIFYKRIKKIFFVDAIPKSPSGKILRKDLKARLAVGLLK
>rna-XM_016691905.1
MEKSGYGNDGIYRSLRPPFYYPKHQNLSMISFLFRNVSSYPDKPALIDADNGETLTFSQFRSSVSRICHGLVNQMGIKKDDVVLIFAPNSIQFPLCFFGVIGLGAIATTVNPMYTVNEVTKQVNDCKPKVIITVPELLDKVSKFGLDILLIGKKENLNLSANSRVVMYDELVGKAGYFDLDGTVIRQSDTAALLYSSGTTGVSKGVVLTHRNFISAGLMVTSDQELAGEMHNVFLCVLPMFHVFGLAVIMYSQLQRGNAIVSMSKFDLEMVLKNVDKYRVTNLWIVPPVVLALAKNPVVKKYNLTSLKQIGSGAAPLGKELMEECAKNLPQTVVMQGYGMTETCGIVSVENQFAGPRHTGSAGTLVPGVEAQIVSVDKPKPLPPGKLGEIWVRGPNMMKGYFNNPQATKLTIDNQGWVHTGDLGYFNEEGMLYVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDAEAGEVPVAYVVRSPNSSLTEVDVQKFIADQVAPFKRLKKVTFINSVPKSVSGKILRRELIEKVRSKL
>rna-XM_016693896.1
MSEAAFQDATTKEMLHRGSVGRLLVNSKAKIRDSKTVIGLPPGEKGELLIKSPIIMQGYIGDPKMTSETLIPSGWLRTSDLCYIDHQGYLLVADRMKELIKYKGYQVTPSGLEQLLQSHPEIVDAAVISYPDEEAGLLPMTFVSETSLKHFLQRTSN
MGTHVAECTQQQEEGEHIFRSRYPPVDVPDNVTLPDFVLHNVELYADRLAFVDATTGKGYTYGEVARDIRRFAKALRSLGLRKGRVVLVVLPNVPEYAIVALGIMAAGGVFSGANPAAHSSEIMKQVESADGKLIVSDLPTYHKVKDCGLPVIILGEERVEGTIHWDELLEAADRASSRTDHITNQEDEIVQQSDLCALPFSSGTTGLSKGVMLTHRNLVANLCSTLFSISPEMVGQVTTLGLIPFFHIYGITGICCATIRNKGKVVVMRRYELRAFLNALITHEVTFAPIVPPIILALVKNPIVDEFDLKKLKLRSIMTAAAPLAPEILNEFEKKFPDVQVQEAYGMTEHSCITLSHSNQHIAKRNSVGFILPNLGVKFVDPDTGRSLPKNTPGEICVKSQCVMKGYYKNESETCLTIDKDGWLHTGDIGYIDDDGDIFLVDRIKELIKYKGFQVAPAELEGILLTHPSVEDAAVVGLPDEEAGEIPAAWVVLNSKAKESHEDIINFVASTAAHYKRVRVVQFVDSIPKSPSGKIMRRLIKEKMLEKLKEGRE
>rna-XM_016708649.1
MASVATVEAQKAEISSTVIPPSNQNQSSEELHVFRSRLPDIVISNDIPLHVYLFEKLSEFQERTCLIAGNTGQTFTFGETHFICQKIAAGLTNIGIKKGDVIMTFLQNCTEFVFTFLAASMIGSVITTANPFYTKSEAFKQLKASNAKLIVTQSQYVDKFRDPVENDPKINEDFLVVTIDDPPENCLHFSVLAEANADDMPKGVVIQPEDPVALPFSSGTTGLPKGVILTHKSLITGVAQLVDGDNPNLYLKHQDVVLCVLPLFHIFALNSVLLVSLRAGASVLLMQKFEIGTLLELIQKYRVSVAAVVPPLVLALAKNPMVDSFDLSSIRLVLSGAAPLGIWYDRGRTSSNNVSIICKATSFNQVRFMWVCGSKCGP*GGRPRNRWLP*PQPTR*NLHSRFSNHERLFE***GHCTNH*R*WMAPHWRYRIC**R**NIHRR*SQRTHQVQRFPGATS*A*VTSSKPSRYCRCCCCAAKG*CCRGSAGCICSPFGPRL*TY*RSYKGIYCQTGGVL*EIAQGVFYSCNSKVSIWKDTEERTESQTGCNSLL
>rna-XM_016707524.1
MPMENETRDLIFRSKLHDIYIPKHLPLHSYCFENISEFNSRPCLIDGANDQIYSYAEVELTSRKVAVGLNKLGVQQKDTIMILLPNSPEFVFAFMGASYLGAISTMANPLFTPAEVLKQAKASSAKIIITLACYIGKVKDYATENDVKLICIDSAPEGCIHFSELTQSDEHEIPDVKIQPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENANLYMHSEDVLMCCLPLFHIYSLNSVLLCGLRIGAAILIMQKFDIVHFLELIQKYKVTIGPFVPPIVLAIAKSPLVDHYDLSSVRTVMSGAAPLGKELEDTVRTKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPDTGCSLPRNQPGEICIRGDQIMKGYLNDLESTTRTIDKEGWLHTGDMGFIDNDDELFIVDRLKELIKYKGFQVAPAELEALLLNHPNISDAAVVPMKDEQAGEVPVAFVVRSNGSTITEDEVKDFVSKQVVFYKRIKRVFFVETVPKSPSGKILRKDLRARLAAGVTN
>rna-XM_016722940.1
MPMENEAKQGDIIFRSKLPDIYIPNHLSLHSYCFENISEFSSRPCLINGANNQIYTYADVELNSRKVAAGLHKQFGIQQKDTIMILLPNSPEFVFAFLGASYLGAISTMANPLFTPAEVVKQVKASNAEIIVTQACHVNKVKDYALENDVKIVCIDSAPEGCVHFSELIQADEHDIPEVQIKPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYIHSEDVMLCVLPLFHIYSLNSVLLCGLRVGAAILIMQKFDIVPFLELIQNYKVTIGPFVPPIVLAIAKSPMVDNYDLSSVRTVMSGAAPLGKELEDTVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPDTGNSLHRNQSGEICIRGDQIMKGYLNDPEATAGTIDKEGWLHTGDIGYIDNDDELFIVDRLKELIKYKGLLNHPNISDAAVVPMKDEQAGEVPVAFVVRSNGSTITEDEVKEFISKQVIFYKRIKRVFFVDAVPKSPSGKILRKDLRAKLAAGFPN
>rna-XM_016724135.1
MEMMNKLQNHDHDEFIFRSKLPNIYIPNHLPLHKYCFENISQFSSRTCLINSTTGATYSYIDVELIAKRIALGLHQLGIEQRDVIMLLLPNSPEFVFAFLGALFRGVICTTANPFYTPSEITKQAKASNAKLIITQSLYVDKIKRYAEENEVKIMCTDDDSTPDDCLSFAELLLNCQNDIHLSDSVKILPDDVAALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHSEDVIMCVLPMFHIYSLNSILLCGLRVGATILIMQKFEIKGLMELVEKYKVTIAPFVPPIVLAIAKSPLVDEYDLSSIRMIMSGAAPMGKELEDTVRAKLPNAILGQGYGMTEAGPVLSMCLAFAKQQFEVKSGSCGTVVRNAEMKIVDTNTGAFLPRNHAGEICIRGDQIMKGYLNNPKATEETIDKEGWLHTGDIGYIDDDDQVFIVDRLKELIKYKGYQVAAAELEAMLISNPNISDAAVVPMKDEVAGEVPVAFVVRANGSKISEDEIKQYVSQQVIFYKRINRVFFTEEIPKAPSGKILRKDLRAKLAAGGLAS
>rna-XM_016689754.1
MDPKQVGDTIFRSKLPDIYIPNHLPLHSYCFQNISEFSYRPCLINGSNDQIYTYADVELTSRKVAAGLNKLKIQQKDTIMILLPNSPEFVFSFLGASYVGAISTMANPMFTQAEVVKQAKASKAKLIITQECNLDKVKDYAFENDVKVICIDESSGDLPEGCLHFSNLILNSVFVSEHDPPEVEIQPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPTLYLHSEDVILCISPLFHIYSLVSILLCGLRVGAAILIMQKFDIVSFFELVEKYKVTIGPFVPPIVLAISKSPVVDNYDLSSVRRVMCGAAPLGKGLEDAVRTKFPHAKFGQGYGMTEAGAPMSMCLAFAKEPFEIKSGACGTVIRNAEMKIVDPDTGISLPRNKPGEICIRGDQIMKGYLNDPEATARTIDKEGWLHSGDIGYIDEDDELFIMDRLKELIKYKGFQVAPAELEALLLNLPDISDVAVIPMKDEEAGEVPVAFVVRSNGSTITEHEIKDFIYKQVIFYKRIKKIFFVDAIPKSPSGKILRKDLKARLAVGLLK
>rna-XM_016691905.1
MEKSGYGNDGIYRSLRPPFYYPKHQNLSMISFLFRNVSSYPDKPALIDADNGETLTFSQFRSSVSRICHGLVNQMGIKKDDVVLIFAPNSIQFPLCFFGVIGLGAIATTVNPMYTVNEVTKQVNDCKPKVIITVPELLDKVSKFGLDILLIGKKENLNLSANSRVVMYDELVGKAGYFDLDGTVIRQSDTAALLYSSGTTGVSKGVVLTHRNFISAGLMVTSDQELAGEMHNVFLCVLPMFHVFGLAVIMYSQLQRGNAIVSMSKFDLEMVLKNVDKYRVTNLWIVPPVVLALAKNPVVKKYNLTSLKQIGSGAAPLGKELMEECAKNLPQTVVMQGYGMTETCGIVSVENQFAGPRHTGSAGTLVPGVEAQIVSVDKPKPLPPGKLGEIWVRGPNMMKGYFNNPQATKLTIDNQGWVHTGDLGYFNEEGMLYVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDAEAGEVPVAYVVRSPNSSLTEVDVQKFIADQVAPFKRLKKVTFINSVPKSVSGKILRRELIEKVRSKL
>rna-XM_016693896.1
MSEAAFQDATTKEMLHRGSVGRLLVNSKAKIRDSKTVIGLPPGEKGELLIKSPIIMQGYIGDPKMTSETLIPSGWLRTSDLCYIDHQGYLLVADRMKELIKYKGYQVTPSGLEQLLQSHPEIVDAAVISYPDEEAGLLPMTFVSETSLKHFLQRTSN
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University