Enzyme
Found in hops (Humulus lupulus). The enzyme can also methylate xanthogalenol.
OMT
Enzyme
Xanthohumol 4-O-methyltransferase
Enzyme name
EC:2.1.1.338
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:desmethylxanthohumol 6'-O-methyltransferase
Sysname
S-adenosyl-L-methionine + desmethylxanthohumol = S-adenosyl-L-homocysteine + xanthohumol [RN:R08004]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];xanthohumol [CPD:C16417]
Product
Species information
Calotropis gigantea
Species name
Mudar (Calotropis gigantea) is a species of eudicot in the family Apocynaceae (dogbane family).
Species info
Gene sequence info
Calotropis_gigantea.OMT.fa
Download
>cal_g009149.t1
MGKDDADENEEIQAQMDIWRYAFGFTEMAVVKCAIELGIADVLESHHGPVPLDHLSSSLGCSPSALYRIMRFLTNRGIFEQVGAASYAQTPLSRLLTRNGEKSMAALVLLESSPVMLEPWHGLRGRVLADGTPAFEAAHGEDVWQYAEKNPSHSKLINDAMACCARLAVSAIIEGCPEVFRSEGIRSLVDVGGGDGTTLGKLVKARPWIRGINFDLPHVVSVAPRRCGVEHVGGDMFKSVPKADAAFLMSVLHDWGDDECIQILKNCKEAIPREQGKVIIVEAVIDEEEGKGEGKDKLKDVGLMLDMVMMAHTTTGKERTSKDWAYVLSEAGFSRHTVKRIQAVQSVIEAYP*
>cal_g009234.t1
MAVSDKSSELLKAEAHIWNQTFSFKNSACLKCAVQLGIADAIEKHGKPMSLSELTAALPIHPSKSPYLYRLMRILVNSAFFTDGITGYALTPAARLLLQDDPLNARDFVLLVLDPVMVKPWNALSDWFQNGIDDDNEKAPFDTAHGKNFWDYTAEEPRLGKLFNDAMASDSNLITNVLMQDCKFVFEGLTSLVDVGGGTGTVARAIVKAFPKLNCTVFDLPHVVANQESMKNLDFVAGDMLEKIPSANSILLKWILHNWSDEDCVKILRNCKKAIPAKENGGKVIIIDMKEPRKNGHLFSAKLVSAAARYFPFWVKKSP*
>cal_g009015.t1
MVDPVHRSAFHYLNEWFRNDDPSAFHTAQGMSYWDYAGQNPDFNDLFNLAMARNTEVVSEALARKWEHVFEGLTSVVDVGDAIPNRDKGGKVIIIELNGEADDEEKEKEGGVLWSTVRALHDLQMMAIHGGKERSKKDWKSIFLAAGFSTDYRLSFRAIACGLLCRSILD*
>cal_g019126.t1
MNGSCDDRDHDQDQELLQAQAHIWNHIFNFINSMSLKCAVELGIPDVIHNLNLQHSGGKPATVSELIEALKIDKAKTPFVSRLMRILTHSGFFVRIKTVGSEKEEAAYALTSASKLLLKENPLSVSPFLLAMLDPILTDPWHRLSDWFRKDDLNPFVTAHGKQLWEMADQEPRLNQFFNKAMASDCQFVSSLITGNNNNNRVFEGLNSLVDVGGGTGTMAKVIAKVFPEMKCTVLDLPHVVQGLEGTKNLSYVGGDMFQFIPPSDAILLKWILHDWSDEECVKILKKCKEAIPNKEKGGKVIIIDMVIGDEEKNSGGYDSGATTETKLFFDMLMMVLVTGSERQEKHWAKLFFQAGFSDYKITPILGLRSLIEVYY*
>cal_g019125.t1
MNASCDENDQDQELLQAQAHIWNHIFNFINSMSLKCAVELGIPDAIHNLHGDGKPATVSELIEALKIDKAKTPNGVSAHANTDSLGFEASTERKLMRPKNGLAGDSARMNRLFTSSDAVLLCFG*
>cal_g011562.t1
MDALAKSGNWSGRSDHMAEDSRADLRTRAPFVKEYFNPPTFVSPLIQADKRVTGKGYIIQLKIRAMNYTNHHEVKSAASDEEELLQVQAQAHIWNHTFSFINSMSLKCAVQRGIPDIIHNHGKPMTLSQLMDALKLDSAKAPCMHHLMRMLIHSGFFLTTKMAENDDDENRGGLYSNF*
>cal_g019124.t1
MNKEAVMMNGGYDQDQELLQAQAHIWNHIFSFINSMSLKCAVELGIPDVIHYLYLRGGGNPATVSEIIDALKLDKAKAPFLSRLMRILTHSGFFIRAKKINVDGNDEKEKEEEEEEGYILTSASKLLLKDNPLSLSPFLHALLDPIMTEPWHRLSDWFRSHHDTSPFVTNHGKEFWEMAGQEPRFNNFFNEAMASDCRLVSSLIIGNNEQVFEGLSSLVDVGGGTGNLSKAIAKTFPEMKCTVMDLPQVVQGLKGTKNLSYVGGDMFQAIPPAHAILLKSILHDWSDEESIKILKKCKEVILSREKGGKIIIIDMVLGEDNHEITETKLSSDMFMMVLVTGRERQEKDWKKIFMKAGFSDYKITPILGLRSLIELYY*
>cal_g013844.t1
MMNTNLVVKSEASPSDDDDEEILQAQAHLWNHTVSFINSMSLKCSVELGIPDIIYNHGKPITLSQLVDALKLDSAKAPFIHRLMNMLIPSVASLLSQIWQEMMRKRKRKLIIFSFLFLSFFSKIAHEVSARYCYPSLIQSRQRHGSSA*
>cal_g011560.t1
MNTNHQMVKSEAFDDEELLQAQAHIWNHTFSFINSTSLKCAVQLGIPDIIHSHGKPMTLSQLMDALKLDSAKAPCMHRLLRMLIHSGFFVTTKMIGNDEKEEEKEAYILSSFASKLLLKDSPWSFRSFLLFQLDPIMTAPWQCLADWFRSNDLHNSFVAAHGKSFWEIAEQEQRLNHFFNEAMASDSRLVSSLIVENNNYKRVFEGLSSLVDVGGGTGNMAKAIAKVSPAIKCTVLDLPRIVQGLEGTKNLSYFGGDMFHFIPPSDAVLLKWILYDWSDEDCVKILKKCKEAIPSKEKGGKMMIIEIVLGDESKIEDDSKATETQLFFNMQMIVMVNGKERNEKDWAKLFFQAGFSSYKITLLLGLRSLIEVYYH*
MGKDDADENEEIQAQMDIWRYAFGFTEMAVVKCAIELGIADVLESHHGPVPLDHLSSSLGCSPSALYRIMRFLTNRGIFEQVGAASYAQTPLSRLLTRNGEKSMAALVLLESSPVMLEPWHGLRGRVLADGTPAFEAAHGEDVWQYAEKNPSHSKLINDAMACCARLAVSAIIEGCPEVFRSEGIRSLVDVGGGDGTTLGKLVKARPWIRGINFDLPHVVSVAPRRCGVEHVGGDMFKSVPKADAAFLMSVLHDWGDDECIQILKNCKEAIPREQGKVIIVEAVIDEEEGKGEGKDKLKDVGLMLDMVMMAHTTTGKERTSKDWAYVLSEAGFSRHTVKRIQAVQSVIEAYP*
>cal_g009234.t1
MAVSDKSSELLKAEAHIWNQTFSFKNSACLKCAVQLGIADAIEKHGKPMSLSELTAALPIHPSKSPYLYRLMRILVNSAFFTDGITGYALTPAARLLLQDDPLNARDFVLLVLDPVMVKPWNALSDWFQNGIDDDNEKAPFDTAHGKNFWDYTAEEPRLGKLFNDAMASDSNLITNVLMQDCKFVFEGLTSLVDVGGGTGTVARAIVKAFPKLNCTVFDLPHVVANQESMKNLDFVAGDMLEKIPSANSILLKWILHNWSDEDCVKILRNCKKAIPAKENGGKVIIIDMKEPRKNGHLFSAKLVSAAARYFPFWVKKSP*
>cal_g009015.t1
MVDPVHRSAFHYLNEWFRNDDPSAFHTAQGMSYWDYAGQNPDFNDLFNLAMARNTEVVSEALARKWEHVFEGLTSVVDVGDAIPNRDKGGKVIIIELNGEADDEEKEKEGGVLWSTVRALHDLQMMAIHGGKERSKKDWKSIFLAAGFSTDYRLSFRAIACGLLCRSILD*
>cal_g019126.t1
MNGSCDDRDHDQDQELLQAQAHIWNHIFNFINSMSLKCAVELGIPDVIHNLNLQHSGGKPATVSELIEALKIDKAKTPFVSRLMRILTHSGFFVRIKTVGSEKEEAAYALTSASKLLLKENPLSVSPFLLAMLDPILTDPWHRLSDWFRKDDLNPFVTAHGKQLWEMADQEPRLNQFFNKAMASDCQFVSSLITGNNNNNRVFEGLNSLVDVGGGTGTMAKVIAKVFPEMKCTVLDLPHVVQGLEGTKNLSYVGGDMFQFIPPSDAILLKWILHDWSDEECVKILKKCKEAIPNKEKGGKVIIIDMVIGDEEKNSGGYDSGATTETKLFFDMLMMVLVTGSERQEKHWAKLFFQAGFSDYKITPILGLRSLIEVYY*
>cal_g019125.t1
MNASCDENDQDQELLQAQAHIWNHIFNFINSMSLKCAVELGIPDAIHNLHGDGKPATVSELIEALKIDKAKTPNGVSAHANTDSLGFEASTERKLMRPKNGLAGDSARMNRLFTSSDAVLLCFG*
>cal_g011562.t1
MDALAKSGNWSGRSDHMAEDSRADLRTRAPFVKEYFNPPTFVSPLIQADKRVTGKGYIIQLKIRAMNYTNHHEVKSAASDEEELLQVQAQAHIWNHTFSFINSMSLKCAVQRGIPDIIHNHGKPMTLSQLMDALKLDSAKAPCMHHLMRMLIHSGFFLTTKMAENDDDENRGGLYSNF*
>cal_g019124.t1
MNKEAVMMNGGYDQDQELLQAQAHIWNHIFSFINSMSLKCAVELGIPDVIHYLYLRGGGNPATVSEIIDALKLDKAKAPFLSRLMRILTHSGFFIRAKKINVDGNDEKEKEEEEEEGYILTSASKLLLKDNPLSLSPFLHALLDPIMTEPWHRLSDWFRSHHDTSPFVTNHGKEFWEMAGQEPRFNNFFNEAMASDCRLVSSLIIGNNEQVFEGLSSLVDVGGGTGNLSKAIAKTFPEMKCTVMDLPQVVQGLKGTKNLSYVGGDMFQAIPPAHAILLKSILHDWSDEESIKILKKCKEVILSREKGGKIIIIDMVLGEDNHEITETKLSSDMFMMVLVTGRERQEKDWKKIFMKAGFSDYKITPILGLRSLIELYY*
>cal_g013844.t1
MMNTNLVVKSEASPSDDDDEEILQAQAHLWNHTVSFINSMSLKCSVELGIPDIIYNHGKPITLSQLVDALKLDSAKAPFIHRLMNMLIPSVASLLSQIWQEMMRKRKRKLIIFSFLFLSFFSKIAHEVSARYCYPSLIQSRQRHGSSA*
>cal_g011560.t1
MNTNHQMVKSEAFDDEELLQAQAHIWNHTFSFINSTSLKCAVQLGIPDIIHSHGKPMTLSQLMDALKLDSAKAPCMHRLLRMLIHSGFFVTTKMIGNDEKEEEKEAYILSSFASKLLLKDSPWSFRSFLLFQLDPIMTAPWQCLADWFRSNDLHNSFVAAHGKSFWEIAEQEQRLNHFFNEAMASDSRLVSSLIVENNNYKRVFEGLSSLVDVGGGTGNMAKAIAKVSPAIKCTVLDLPRIVQGLEGTKNLSYFGGDMFHFIPPSDAVLLKWILYDWSDEDCVKILKKCKEAIPSKEKGGKMMIIEIVLGDESKIEDDSKATETQLFFNMQMIVMVNGKERNEKDWAKLFFQAGFSSYKITLLLGLRSLIEVYYH*
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University