Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Callicarpa americana
Species name
American beauty-berry (Callicarpa americana) is a species of eudicot in the family Lamiaceae (mint family).
Species info
Gene sequence info
Callicarpa_americana.CHS.fa
Download
>Calam.01G035100.1
MATVEEFRRAQRAEGPATILAIGTSNPLNCIDQSTYPDYFFRVTNSEHKIELKEKFKRMCEKSMIKKRYMHLTEEILKENPNMCSYTTPSLDARQDIVVVEVPKLGKKAAQKAIREWGQPKSKITHLVFCTTSGIDMPGADYQLLKLLGLHPSVKRFMMYQQGCFAGGTVLRLAKDLAENNVGARVLAVCSEITVASFRGPSDTHLDNLVGQALFGDGAAAVIVGSDPVVGVERPLFQLVSAMQTLIPDCERAIDGHLREVGILFHILKEVPGLISNNIEKSLKEAFDPLGISDWNSIFWMAHPGGPSIFDQIEAKLALKPEKLRSTRHVLSEYGNMLSAGVLFVLDEMRKVSVKGGLSSTGEGLDWGVLFGFGPGLTIETVVLRSMPI
>Calam.01G035300.1
MFATTISTTTSSLHNHRNLFLANMVRVEEVRRAQRAEGPATILAIGTANPLNCVDQSTFPDYYFRITNSEHMTELKEKFKRMCKKSMIKKRYMHLTEEILKENPNICSYMAPSLDARQDIAVVEVPKLGKEAAQKAIREWGQPKSKITHLIFCTTSGVDTPGADYQLTKLLGLRPTVKRFMMYQQGCFGGGTVLRMAKDLAENNAGARVLVVCSEITVVSFRGPSDDLENLVGQVLFGDGAAAVIVGSDPVIGVEQPFFQLASAAQTLLSEGEGTIDGHLREAGLIIYISKDIPGLISKNIEKCLKESFEPLGISDWNSIFWVAHPGGPAILDQVEAKLALKPEKLQSTRHVLSEYGNMGSTCVLFVLDEMRKVSAKEGLSSTGEGLDWGVLLGFGPGLTIETVVLHSMPIN
>Calam.01G035200.1
MVTVEEVRRAQRAEGPATILAIGTANPLNCVDQSTYSDYYFRVTSGEHKTELKEKFKRMCEKSMIKKRYMHLTEEILKENPNMCSYKAPSLDARQDIVVVEVPKLGKEAAQKAIREWGQPKSKITHLVFCTTSGIDMPGADYQLTKLLGLHPSIKRFMIYQQGCFAGGTVLRLAKELAENNAGARVLVVCSENTVASFRGPSDAHLDNLVGQALFGDGASAVIVGSDPMVGVERSLFQIVSAIQTFIPDSEEAINGHLGEAGMIFHIQKYVPNLISKNIEKSLKEAFEPLGISDWNSIFWIAHPGGPAILDQIEEKLALKPEKLRSTRHVLSEYGNMSSACVLFILDEMRKVSAKKGLSSTGEGLDWGVLFGFGWGLTVETVVLHSMPIN
>Calam.02G035500.1
MVTVEEIRRAQRAEGPATILAIGTATPSNCVDQSTYPDYYFRITDSEHKTELKEKFKRMCEKSMIKKRYMHLTEEILKENPNICAYMAPSLDARQDIVVVEVPKLGKEAAQKAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPSVKRFMMYQQGCFAGGTVLRMAKDLAENNAGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIVGSDPVVGVERPLFQLVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLKEAFTPLGISDWNSIFWIAHPGGPAILDQVEAKLGLKPEKLRSTRHVLSEYGNMSSACVLFILDEMRKSSTKEGLSSTGEGLDWGVLFGFGPGLTVETVVLHSVPIN
>Calam.04G222800.1
MSQININNGETKQYPSPAKRSSTPGKATILAIGKAFPRQLVPQDLLVEGYIRDTNCDDLAIKEKLERLCKTTTVKTRYTVMSKEILNQYPELATEGSPTITQRLEIAHPAVLEMAKEASLACLKEWKRPAEDITHIVYVSSSEIRLPGGDLYLATELGLRNDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKSRPYDLVGAALFGDGAAAVIIGSDPITEKESPFMELNYAIQQFLPGTNNVIDGRLSEEGIYFKLGRDLPQKIEENIEEFCKKLMAKGGLKEYNDLFWAVHPGGPAILNRLESTLGLERKKLECSRRALMDFGNVSSNTIFYVMEYMREELKKEDAEEWGLALAFGPGITFEGILLRSL
>Calam.04G020200.1
MGSEETMQCLKNANPGKATILALGKAFPHQLVLQDFLVDGYFRNTNCDDPELKQKLTRLCKTTSVKTRYVVMSEEILNKYPELAMEGIPTVKQRLDICNSAVTEMAIEASQSCINKWGRSVSDITHLVYVSSSEARLPGGDLYLAKGLGLRPDTQRVMLYFSGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGYRPPSADRPYDLVGVALFGDGAGAMIIGSNPDLKTEKRPLFELHTAIQHFLPGTEKIIDGKLTEEGISFRLDKELPQIIEDNIQDFCIELMGFAGNLEKDYNKLFWAVHPGGPAILNKLEKKLELLPEKLNASRRALADYGNASSNTIVYVLEYMLEEAKSVKNDENEWGLILAFGPGITFEGILTRNLTV
>Calam.06G247900.1
MSQGNNNGGTKQHPSPVAPPVATPGKATVLAIGKAFPSQLVPQDCLVEGYIRDTNSDDLAIKEKLERLCKTTTVKTRYIVLSKEILNKYPELATEGSPTIKQRLDIANPAVVEMAKEASLACLKEWKRPASDITHIVYVSSSEIRLPGGDLYLASELGLKYDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNTSRPYDLVGAALFGDGAAAVIIGTDPIAGKEFPFMELNFAVQQFLPGTHNVIDGRLSEEGMNFRLGRDLPQKIEENIEEFCKKLMAKTGLEDYNDLFWGPIGKHSRFKKPQAGMQKEGTDGFWKC
>Calam.S003450.1
MAPPPLLWVPTRWWGWKRPLFQLVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLKEAFTPLGISDWNSIFWIAHPGGPAILDQVEAKLGLKPEKLRSTRHVLSEYGNMSSACVLFILDEMRKSSTKEGLCSTGEGLDWVCCLDSGRASPSRLWYCIACLSIEGLLHN
>Calam.S003700.1
MVTVEEIRRAQRAEGPATILAIGTATPSNCVDQSTYPDYYFRITDSEHKTELKEKFKRMCEKSMIKKRYMHLTEEILKENPNICAYMAPSLDARQDIVVVEVPKLGKEAAQKAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPSVKRFMMYQQGCFAGAPSFAWPKIWRRTMPELGSCCLLGNHGGDFPRPE
MATVEEFRRAQRAEGPATILAIGTSNPLNCIDQSTYPDYFFRVTNSEHKIELKEKFKRMCEKSMIKKRYMHLTEEILKENPNMCSYTTPSLDARQDIVVVEVPKLGKKAAQKAIREWGQPKSKITHLVFCTTSGIDMPGADYQLLKLLGLHPSVKRFMMYQQGCFAGGTVLRLAKDLAENNVGARVLAVCSEITVASFRGPSDTHLDNLVGQALFGDGAAAVIVGSDPVVGVERPLFQLVSAMQTLIPDCERAIDGHLREVGILFHILKEVPGLISNNIEKSLKEAFDPLGISDWNSIFWMAHPGGPSIFDQIEAKLALKPEKLRSTRHVLSEYGNMLSAGVLFVLDEMRKVSVKGGLSSTGEGLDWGVLFGFGPGLTIETVVLRSMPI
>Calam.01G035300.1
MFATTISTTTSSLHNHRNLFLANMVRVEEVRRAQRAEGPATILAIGTANPLNCVDQSTFPDYYFRITNSEHMTELKEKFKRMCKKSMIKKRYMHLTEEILKENPNICSYMAPSLDARQDIAVVEVPKLGKEAAQKAIREWGQPKSKITHLIFCTTSGVDTPGADYQLTKLLGLRPTVKRFMMYQQGCFGGGTVLRMAKDLAENNAGARVLVVCSEITVVSFRGPSDDLENLVGQVLFGDGAAAVIVGSDPVIGVEQPFFQLASAAQTLLSEGEGTIDGHLREAGLIIYISKDIPGLISKNIEKCLKESFEPLGISDWNSIFWVAHPGGPAILDQVEAKLALKPEKLQSTRHVLSEYGNMGSTCVLFVLDEMRKVSAKEGLSSTGEGLDWGVLLGFGPGLTIETVVLHSMPIN
>Calam.01G035200.1
MVTVEEVRRAQRAEGPATILAIGTANPLNCVDQSTYSDYYFRVTSGEHKTELKEKFKRMCEKSMIKKRYMHLTEEILKENPNMCSYKAPSLDARQDIVVVEVPKLGKEAAQKAIREWGQPKSKITHLVFCTTSGIDMPGADYQLTKLLGLHPSIKRFMIYQQGCFAGGTVLRLAKELAENNAGARVLVVCSENTVASFRGPSDAHLDNLVGQALFGDGASAVIVGSDPMVGVERSLFQIVSAIQTFIPDSEEAINGHLGEAGMIFHIQKYVPNLISKNIEKSLKEAFEPLGISDWNSIFWIAHPGGPAILDQIEEKLALKPEKLRSTRHVLSEYGNMSSACVLFILDEMRKVSAKKGLSSTGEGLDWGVLFGFGWGLTVETVVLHSMPIN
>Calam.02G035500.1
MVTVEEIRRAQRAEGPATILAIGTATPSNCVDQSTYPDYYFRITDSEHKTELKEKFKRMCEKSMIKKRYMHLTEEILKENPNICAYMAPSLDARQDIVVVEVPKLGKEAAQKAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPSVKRFMMYQQGCFAGGTVLRMAKDLAENNAGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIVGSDPVVGVERPLFQLVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLKEAFTPLGISDWNSIFWIAHPGGPAILDQVEAKLGLKPEKLRSTRHVLSEYGNMSSACVLFILDEMRKSSTKEGLSSTGEGLDWGVLFGFGPGLTVETVVLHSVPIN
>Calam.04G222800.1
MSQININNGETKQYPSPAKRSSTPGKATILAIGKAFPRQLVPQDLLVEGYIRDTNCDDLAIKEKLERLCKTTTVKTRYTVMSKEILNQYPELATEGSPTITQRLEIAHPAVLEMAKEASLACLKEWKRPAEDITHIVYVSSSEIRLPGGDLYLATELGLRNDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKSRPYDLVGAALFGDGAAAVIIGSDPITEKESPFMELNYAIQQFLPGTNNVIDGRLSEEGIYFKLGRDLPQKIEENIEEFCKKLMAKGGLKEYNDLFWAVHPGGPAILNRLESTLGLERKKLECSRRALMDFGNVSSNTIFYVMEYMREELKKEDAEEWGLALAFGPGITFEGILLRSL
>Calam.04G020200.1
MGSEETMQCLKNANPGKATILALGKAFPHQLVLQDFLVDGYFRNTNCDDPELKQKLTRLCKTTSVKTRYVVMSEEILNKYPELAMEGIPTVKQRLDICNSAVTEMAIEASQSCINKWGRSVSDITHLVYVSSSEARLPGGDLYLAKGLGLRPDTQRVMLYFSGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGYRPPSADRPYDLVGVALFGDGAGAMIIGSNPDLKTEKRPLFELHTAIQHFLPGTEKIIDGKLTEEGISFRLDKELPQIIEDNIQDFCIELMGFAGNLEKDYNKLFWAVHPGGPAILNKLEKKLELLPEKLNASRRALADYGNASSNTIVYVLEYMLEEAKSVKNDENEWGLILAFGPGITFEGILTRNLTV
>Calam.06G247900.1
MSQGNNNGGTKQHPSPVAPPVATPGKATVLAIGKAFPSQLVPQDCLVEGYIRDTNSDDLAIKEKLERLCKTTTVKTRYIVLSKEILNKYPELATEGSPTIKQRLDIANPAVVEMAKEASLACLKEWKRPASDITHIVYVSSSEIRLPGGDLYLASELGLKYDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNTSRPYDLVGAALFGDGAAAVIIGTDPIAGKEFPFMELNFAVQQFLPGTHNVIDGRLSEEGMNFRLGRDLPQKIEENIEEFCKKLMAKTGLEDYNDLFWGPIGKHSRFKKPQAGMQKEGTDGFWKC
>Calam.S003450.1
MAPPPLLWVPTRWWGWKRPLFQLVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLKEAFTPLGISDWNSIFWIAHPGGPAILDQVEAKLGLKPEKLRSTRHVLSEYGNMSSACVLFILDEMRKSSTKEGLCSTGEGLDWVCCLDSGRASPSRLWYCIACLSIEGLLHN
>Calam.S003700.1
MVTVEEIRRAQRAEGPATILAIGTATPSNCVDQSTYPDYYFRITDSEHKTELKEKFKRMCEKSMIKKRYMHLTEEILKENPNICAYMAPSLDARQDIVVVEVPKLGKEAAQKAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPSVKRFMMYQQGCFAGAPSFAWPKIWRRTMPELGSCCLLGNHGGDFPRPE
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University