Enzyme

Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.

HIDH

Enzyme

2-hydroxyisoflavanone dehydratase

Enzyme name

EC:4.2.1.105

Entry

Lyases;Carbon-oxygen lyases;Hydro-lyases

Class

2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)

Sysname

(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O

Reaction

daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]

Product

Species information

Actinidia chinensis

Species name

Golden kiwifruit (Actinidia chinensis) is a species of eudicot in the family Actinidiaceae (Chinese gooseberry family).

Species info

Gene sequence info

Actinidia_chinensis.HIDH.fa

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>transcript:PSS19192
MGSITTEIAHDFSPFFRVHKDGRIERFRKPEFTPTSDDPQSAVRSKDVVISTETAVSVRLFLPTAAAALNQKLPVLIYVHGGGFCLGSASSPKFHHFAASLADGANVIAVSVDYRLAPDHPLPIAYEDSWDALKWVFSHSDGAGAEPWLNDHADFGRVFVGGDSAGANIANNVAIRAGIDGLKFLGLILIHPYFGGKGFEKMYKYMCPSSSGFNDDPRLNPAMDPGLPKMACERVLFCLAEKDWLVERGREYYEALGKSGWGGERAIMETEGEGHGFHLFDPNCEKTAALMKQLVSFLTRD
>transcript:PSS19757
MDSSRPEVSHEVPPYLRVYKNGTIERLFGNEVAPASFDPQTGVESKDTMITPEAGVFARLYRPSNTPNSQKLPLVVYFHGGAFFISSISDPKYHHSLNVLVAKAKIILISVDYRRAPEHPLPAAYEDSWAALQWVASHASGGGVESWLKGKVDFSKVFLAGDSAGANISHHLAIRAGSNPIGGMKLHGIIMIHPYFWGEKPIGSEAQDPMRKAMVDGWWRFVCPSDRGNDDPLINPVADGAPSLSGMACNRVIVCVAGKDILRDRGRLYYESLVKSEWLGKAVIVEIEGEDHVFHILDPNCEKALYMTECLASFINQE
>transcript:PSS17587
MTCYTTSACFFLFLLFVIASGDCDAAKGGPYLPLQIPKPEVNYKDVTIVDGVCARLYVPISATPNQKLPLVVYFHGGAFTMFSAFLPPYDDYLYSLSTKANVVALSVEYRRPLTYPIPIPFDDSWAAVKWVASHSAGRGPEELVNNHVDFTRVFLQGDSAGGTIAHNIALRAGLEKPEGLNIAGLALMHPYFWGSKPISTRETRNETESALAASVWFVAGGSNIDDPRVNPLEDPNLSSLGCNKVLVVIAEQDIFRDRGFYYYDALGKSGWKGKAEVMETPGEHVFYIHQPNTTYAEDIFGRVSSFVSCA
>transcript:PSS17243
MDSSRPEVSHEVPPYLRVYKDGTIERLFGNEVAPASFDHQTGVESKDTVITPETGVSARLYRPSNTPNSQKLPLVVYFHGGAFFISSISDPKYHHFLNVLVAKAKIILISVDYRRAPEHPLPAAYEDSWAAFQWAASHVSDGGAESWLLGKVDLSKVFLAGDSAGANIAHHLAIRARSNPVGGMKLRGIIMIQPYFWGEIPIGSESQDPVRKAMVDGWWRFVCLSDRGNDDPLINPVADGAPSLSGLACDRVIVCVAGKDILRDRGRLYYESLVKSEWLGKAEIVEIEGEDHVFHIMDPNCEKALYMMECLASFINQE
>transcript:PSS09425
MATATATATTTTNTSQQPYEVDECRGVLRVYSDGSIVRSPKPSFNVPVHDDGSVLWKDVTFDATHNLQLRLYKPASATEPLPIFYYIHGGGFCIGSRTWPNCQNYCFRLALALRAIVVSPDYRLAPENRLPAAIEDGYAAVKWLRDQAEAAEPDPWLAGVADFSRVFISGDSAGGNIAHNLAVGLGAGSAELGPMVRVRGYVLLAPFFGGTVLTRSESEGPKEAFLNWELIDRFWRLSIPVGETTDHPLVNPFGPGSRPLESLDLDPILVVVGGSDLLKDRAEDYANKLKGWGKKVQYVEFEGQHHGFFTIDPSSQPSNDLMRIIKQFIAEN
>transcript:PSS01128
MSIIVEAPGILQVFSDGSVKRFAPEIAPASCEPSSSKGYKSKDVIIDPSKPITARIFLPDLAPTWSGQLPVIVYFHGGGFCIGSTTWIGYHVFLGDLSVASQSIVLSVDYRLAPENRLPVAYEDCYSSIEWLSKQIRSEPWLERVDLSRVFLSGDSAGGNIAHQVAVMIAQRKRTCPVEPKGLLLIHPYFGSEKRTKREMAEGAEGAVAMNDMFWGLSLPEGSDRDYYGCNFETAVLDSTEWPRFPAVVVHVAELDFLKERGVMYAEFLKKNGVKSVELVEAEGESHVYHALNPESEATRLLQKQMSGFIHNF
>transcript:PSS01127
MSIIVEIPGFLQVFSDGSVKRFAPEIAPASCEPSSKGYKSKDVIIDPSKPITARIFLPDLAPTWSGQLPVIVYFHGGAFCIGSTTWIGCHTFLGDLSVASQSIVLSVDYRLVPENRLPVAYEDCYSSIEWLSKQIRSEPWLERADLSRVFLSGESAGGNIAHQVAVMITQRKRTCPVEPKGLLLIHPYFGSEKRTKREMAEGAEGDVAMNDMFWGLSLPEGSDRDYFGCNFETAVLDSTEWQRFLAVVVHVAELDFLKDRGVMYAEFLKKNGVTSVELVEAEGESHVYHAFHPESEATRLLQKQMSGFIHNF
>transcript:PSR99723
MGSNKLEVSVEVLPYLRVYKDGTIERIAGTEVSPADLDPQTGVVSKDIVIIPETGVSARLYRPNLTSEHKKLPLVVYFHGGAFCISSASDPYYHNSLNILVSKADIVVLSVDYRRSPEHPLPAAYEDSWAALEWVASHSGGGGGSEAWLKDSVDFGRVFLAGDSAGANISHHMAIRAGSTRIDGLKIHGIVMIHPYFWGEEPIGSEVMDPIRKAMVDCWWQFVCPSEKGSDDPLMNPFVDGAPSLSGLACDRVIVCVAEKDILRDRGRLYYEKLAKSGWPGTVEVMETEGEDHVFHIFNPNCEKALNMMKCLASFINQE
>transcript:PSR91187
MTATTLDPSLSQQINTKTHRHGAVVEEIEGLIRVYKDGHVERPQIVPCVMSSLASELVVTSRDIVIDKPTNIWARFYLPKYHGNLPLLVYFHGGGFCVGSAAWSCYHEFLAKLAARAGCLILSVNYRLAPENRLPAAYEDGFKALMWVKQQAICGGGNEWWSKKCNFSSIFLAGDSAGANIAHNVAIRLNSCQSMYIKPLTIKGTILIQPFFGGERRTNSEKYTVEPPRSALSLAASDTYWRLALPPGASRDHPWCNPGVKGSIQLGELGISPTMVCVAEMDILRDRNLDMCAALARAGKQVECVVHKSVGHAFQVLNKSQLSQTRTLEMISHIKAFIIR
>transcript:PSR88257
MTATTLDPSLSLQINTKTHHHGAVVEEIEGLIRVYKDGHVERLQIVPCVASSLAPELGVTSRDIVIDKPTNIWARFYLPKYHENLPLLVYFHGGGFCVGSAAWSCYHEFLAELAARANCLILSVNYRLAPENRLPAAYDDGFKALMWVKQQALCGGGNEWWSKQCNFSSIFLAGDSAGANIARNVAIRLNSCQPMAIKPLTIKGTILIEPFFGGERRTNSEKYAVEPPRSALSLAASDTYWRLALPLGANRDHPWCNPGAKGSIQLGELGISPIMVCVAEMDILRDRNLDMCAALARAGKQVERVVHKGVGHAFQVLNKSQLSQTRTLEMISHIKAFITR
>transcript:PSR85375
MASGDTKEVATDLLPLLRHYKDGTVERFIASPYIPPSPHDPATGVSSKDVTISPLVSARLYLPASATQKLPVLVYFHGGGFCIESAFSLFNHRYVNALVSESNAVAVSVEYRLAPENPLPAAYDDSWAALQWVAYHSVDRGADDKSQHRDSWLAEHADFDRLFIGGDSAGANIVHHLAIRAGSEPLPGDLKILGAFLAQPYFWGSDPIGSESPDLHTEENLIQRIWTCVYPSAPGGIDNPAINPFSPDASSVAALGCARLLVCVSGEDELRERGIRYFEEVKRSGWRGEKIELFEVEGEGHAFHFFGFGSENAKRMITRLASFVSQTRLASS
>transcript:PSR85374
MASNTKEVATELLPLLRVYTDGTIERLIGSPLVPPSLSDPATGVSSKDISISLDVSARVYLPKLTPDTNQQKLPIFVYFHGGGFCVESAFSTLHHRYINLLASRAKVLVVSVEFRLAPEYLLPTAYEDSWAALQWISSHSTEGNNDKDPWLIDYGDFDKVYIGGDTTGANIAHNLAMRGGNEPLHGGVKLRGAFLCQPFFWGSKPIRSESSSGRCRLWEFAYPSAPDGVDNPMINPFATGAPSLAGLGCSKLLVCVGENDVAKERGIHYCDVVRECGWGGEVELYEMQGTSHGSHILDPHSEIAKSLMSRLANFFR
>transcript:PSS33604
MATISLDPRLNLQTGKTNHQNSALVEEIEGIIRVYKDGSVERHLVLPNVSCAVNSELSVTSKDVVIDKFTSLWARLYVPSRQYGKLPLLVYFHGGGFCVGSTSWSCYHNFLSNLASIAGCVIVSVNYRLAPENRLPAAYEDGFKAVMWVKQQALNRSDEEKWWLSRCSFSSVFLAGDSAGANIAHNVATRLGSNGTSDPSILKPLCLKGTILIQPFFGGEMRTESERQTVQPPGSALTLPSSDTYWQLSLPVGANRDHHWCNPLAKGATKVGDYGLPPMMVCISEMDILKDRNLEFCAAMASAGKRVEKVIYRGVGHAFQILHNSHLSQLRTHEMMSHLKAFINH
>transcript:PSS33885
MGLASWRSFWGIVYLYPQNSEISHLSSQPSLSLSPMVSNTKTPPPSDLLPVLRVHKDGTVERLLGSPFVPPSPNDPTTGVSSKDTTISPHVSARLYLPPNTTHQKLPVLVYFHGGGFCIESAFSLLCHRYVTSLVALAKIIVVSVEYRLAPEHPLPAAYEDSWATLQWVSSHTLHQENPKKDPWLTKHGDFERLYIGGDSSGANIAHNMAIKASKGLFGGVRITGVILSHPFFWGSDPVGSEPVLGHDQTLSHRTWALVYPNALGGVDNPMINPFARNGPGLAGLGCCRLLVCVATEDELRERGVKYCDEVRKSGWVGELELFEVEGEGHCFHILNPESDNAKNMMKCLADFLLQ
>transcript:PSS31408
MGSNKLEVSVEVLPYLRVYKDGTIERIAGTEVTPADLDPQTGVVSKDIVIIPETGVSARLYRPNLTLEHKKLPLVVYFHGGAFCISSASDPLYHNSLNILVSKADIVVLSVDYRRSPEHPLPAAYEDSWAALQWVASHSGDGGSEVWLKESVDFGRVFLAGDSAGANISHHMAIRAGLTRIEGLKIHGIVMIHPYFWGEEPIGLEVKDPIRKAMVDCWWRFVCPSEKGGDDPLMNPFVDGAPSLSGLACDRVIVCVAEKDILRDRGRLYYEKLAKSGWPGTVEIMKTEGEDHVFHIFNPSCEKALNMMKCLASFINQ
>transcript:PSS29354
MSASTDELAHGFPPLIRVYKDGRVERLKGTEIAPPSTNPKTGVQSKDIVIDPNTALSARIFIPKITKPNQKLPLVIYFHGGGFCIETAFSPQIHNYADSLAAEANAVVLSVNYRRAPEHPLPIAYNDSWAAIQWVASHSTNGGPEVWLKDYVDFNRFFFAGDSAGANIAHNMGIRVGWEVLDRVKVVGIVLIHPYFGGKDPIGGEIDNVNGKARADYLWMFVCPTSSGLDDPLINPVMDPRLSGLGCDKVLVCVAEKDFLRDRGWYYKEELEKSGWGGVVEIMEAEGEGHGFHMFKPTCDNAVAMLKRVVAFINEDMTH
>transcript:PSS29356
MDSELAYELPPFIRVYKDGKVERLMGTEIVPPSSSDPATGVQSKDIVISPETGVSARLYKPKTISPNKKLPLLVYFHGGAFFVQTAFSPTYQHFLNSLVKEANLIVVSVDYRRAPEHHLPIGYDDSWAAVKWAVSQSTVGGHEAWLKDHVDFDLMFFGGDSAGANIAHNMAIRVGSEGLDGGNLVGIVMMHPYFWGKDPIGSEETSMEVRAVIERFWLLTCPSSPGLDDPWLNPASDPKLSCLGCKRVLVFVAERDALRDRGWFYCEALGKSGWGGEVEIVEAQGEDHVFHLEKPNCEKGKDMVKKMASFVNQDKGHGL
>transcript:PSS29355
MDSATAAIVLDFPLFLRLYSDGRVERFSGTDVVPTSTNPVTGVRSKDIVIDTNTDLSARLFVPKITNPNQKLPLVIYFHGGGFCIETAVSPQYHNYADSLAAEANAVVLSVNYRRAPEHPLPIAYNDSWAAIQWVASHSTNGGPEVWLKDYVDFNRIFFAGDSAGANIAHNMGIRVGSEGLNRVRIVGIVLFHPYFGGKEPIGGEIGNVKGKSFSDKLWMFAYPSSSGSDDPMMNPAMDPGLSGLGCEKVLVCVAERDFLRDRGWYYKEELGKSGWGGVVEIMEAVGEDHVFHLLNPTCDNAVAMLKRVVAFINEDKA
>transcript:PSS29357
MDSATAAIVHDFLPVVRLYSDGRVERFSGTDVVQPSTNPLTGVQSKDIVIDTNTDLSARLFVPKITNPNQKLPLVIYFHGGGFCVETAVSPQYHNYADSLAAEANAVVLSVNYRRAPEHPLPIAYNDSWAAIQWVASHSTNGGPEVWLKDYVDFNRIFFAGDSAGANIAHNMGIRVGSEGLNRVRIVGIVLFHPYFGGKEPIGGEIGNVKGKSFSDKLWMFAYPSSSGSDDPMMNPAMDPGLSGLGCEKVLVCVAERDFLRDRGWYYKEELGKSGWGGVVEIMEAVGEDHVFHLLNPTCDNAVAMLKRVVAFINEDKA
>transcript:PSS26098
MDSSTIEITHEFPAFFRVHKDGRIQRFKPFIYVPPTVDPQTGVISKDITIAPEIELKARIFMPEINGQDQKLPLVLHFHGGGFCIGSPFDAIIYSLLTSLASKARAIVVSVDYRLAPEHPLPIAYDDSWSALQWMAAHSTGKGPDPWLNQHADFGRVFLGGESAGANIAHHVAVRVGSSGFDGFRVHGLFLVHAYFVDHEPNKFTPMIRFLYPGSSGLDDDPKLSPKADPGLCKMGCSKVMVCVASKDLLKPRGEDYCEILKNRGWEGTVELVESEGEDHCFHLFNPTNEKAVVLMQTLASFINQD
>transcript:PSS26097
MDSSEVTHDFPPFFRVYKDGRIERYVAIGYVPPAVDPQTGVESKDVTISQETDLKARIFIPQINSSDPKIPLVVHYHGGAFCIGSPFDALSHSFLTSLASEARAIVVSVDYRLAPEHPLPIAYDDSWSALQWIAAHSTGQGPDPWLNQHADFGRVFLAGESAGANIAHHVAVRAGLAGPGYLQVHGLILVHPFFANNEPDKMIRFLYPGSSGSDNDPRLSPLEDPDLDKLGCSQVIVFVAGKDWLKSRGVGYCEILKNRGWEGTVELVESEGEDHCFHLFNPQSEKAVLLVQSLASFINQD
>transcript:PSS26096
MASITTEIAHDFSPYFRVHKDGRIERFGKPQFIPTSDDPKSAVRSKDVVIFPETAVSVRLFLPTAAAPNQKLPLLIYVHGGAFCVGSASSPKFHHFVASLVADANVVAVSVDYRLAPDHPLPIAYEDSWDALKWVFSHSDGAGAEPWLNDHADFGRVFVGGESAGANIANNLAIRAGIDGLKFLGLILIHPYFGGKVCDKLYKYMCPSSSGVDDDPRLNPAVDPGLPKIACERVIFCLAEKDWLVERGREYYEALGKSGWGGEREIMETEGEGHGFHLLDPNCEKAMALMKQLVSFLTRD
>transcript:PSS24378
MVCEKNIVEEVSGWLRVFDDGSVDRTWTGPPEVKFMAEPVPPHSEFINGVATRDVVIDPKSGLRVRIYLPDTADYEKLPILLHFHGGGFCISQADWYMYYSIYTRLALSAKAICVSVYLRLAPEHRLPAACQDGFSALLWLRSLAQSGSSSSHEPWLNAYADFNRVFLIGDSSGGNLVHQVAAWAGKLDLGPLRLAGAIPIHPGFVRSQRSKSELEEPESPFLTLDMVDKFLKLALPVGSTKDHPITCPMGAEISGLRLPPMLFCVAEKDLIRDTEMEYYEAVKNACNTNNNNYEEVDHVELLISSGMGHSFYLNKIAVDMDDKTAQETQKLIQGIADFINKH

Gene tree

Gene tree

Sheng jun & Dong yang Teams, Yunnan agriculture University