Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Brassica oleracea
Species name
Wild cabbage (Brassica oleracea) is a species of eudicot in the family Brassicaceae (mustard family).
Species info
Gene sequence info
Brassica_oleracea.CHS.fa
Download
>rna-XM_013762833.1
MVMGALSLDEIRKAQRGDGPASILAIGTANPPNQVIQAEYPDYYFRITNSEHMTDLKEKFKRMCDKSMIRKRYMHLTEEFLKDNPNICAFMAPSLDVRQDILVTEVPKLGKEAAVNAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLIKLLGLSPFVKRVMMYHQGCYAGGTVLRLAKDIAENNRGARVLIVCSEITVVTFRGPSETHLDSLVGQSLFGDGAAALIVGSDPDTSAGEKPIFEMVSAAQTILPDSKGAIEGHLKEVGLTFHLLKTVPGLISKNIEKCLQEAFKPLGISDWNSLFWIAHPGGPAILDHVEIKLGLKAAKMKATRHVLSEYGNMSSACVFFILDEMRRRAVEDGAETTGEGLEWGVLFGFGPGLTVETVVLHSVPL
>rna-XM_013762407.1
MVMGALSLDEIRKAQRADGPASILAIGTANPPNQVTQAEYPDYYFRITNSEHMTDLKEKFKRMCDKSVIRKRYMHLTEEFLKDTPNICAFMAPSLDVRQDILVAEVPKLGKEAAVKAIKEWGQPKSKITHLVFCTTSGVAMPGADYQLIKLLGLCPSVKRVMMYHQGCYAGGTVLRLAKDIAENNRGARVLIICAEITVVTFRGPSETQLDSLVGQSFFGDGTAALIVGSDPDTSVGEKPIFEMVSAAQTILPDSQGAIEGHLKEVALTFHLLKTVPGLISKNIEKCLEEAFKPLGISDWNSLFWIAHPGGPSILDHVEIKLGLKAEKMKATRHVLSEYGNMSSACIIHLNSLRERSQDWNKHILNLDMGYYVNLAMKSNGGGPMNVCRVGKR
>rna-XM_013765981.1
MVMVGTTSSLDEIRKAQRADGPAGILAIGTANPANHVLQAEYPHNYFRITNSAYMTDLKEKFKRMCDKSTIRKRHMHLTEEFLKENPNMCAYMAPSLDARQDLVVVEVPKLGKDAAVKAIKEWGQPKSKITHVVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFSDGAAALIVGSDPDVSAGEKPIFEMVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLDEAFKPLGISDWNSLFWIAHPGGPAILDDVEKKLGLKAEKMRATRHVLSEYGNMSSACVLFILDEMRRKSVEDGVATTGEGLEWGVLFGFGPGLTVETVVLHSVPV
>rna-XM_013768106.1
MGSIDATELGSEKKPNPGKATILAIGKAFPQQLVMQEYLVDGYFKTTNCDDPELKQKLTRLCKTTTVKTRYVVMSEEILNKYPELATEGGSTVKQRLDICNDAVTEMAVEASRACIENWGRSISDITHLVYVSSSEARLPGGDLYLAKGLGLSPETHRVLLYFVGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSADRPYDLVGVALFGDGAGAMIVGSDPDPVREKPLFELHTAIQNFLPDTEKTIDGKLTEQGINFTLSRELPQIIEDNVESFCKKLIGKAGLAHKDYNQMFWAVHPGGPAILNRMEKRLNLSPEKLSPSRRALMDYGNASSNSIVYVLEYMLEESRKARNMNEGGNEWGLILAFGPGVTFEGIVARNIDV
>rna-XM_013771363.1
MLATGRVAKQKEIAQSTRRVANQGKATVLALGKAFPSNVVSQENLVEEYLREIKCDDPSIKEKLQHLCKTTTVKTRYTVMSSETMQKYPELATEGSPTIKQRLEIANEAVVQMAYEASLACIKEWGRGVEDITHLVYVSSSEFRLPGGDLYLSAQLGLSNEVQRVMFYFLGCYGGVSGMRVAKDIAENNPGSRVLLTTSETMVLGFRPPNKARPYDLVGAALFGDGAAALIIGADPTESENPFMELHYALQQFLPGTQGVIDGRLSEEGISFKLGRELPQKIEDNIEEFCKKLVAKAGSGSLELNDLFWAVHPGGPAILNGLETKLKLKPEKLECSRQALVDYGNASSNTIFYIMDKVRGELEKKGRGGEEWGLGLAFGPGITFEGFLMRSL
>rna-XM_013766928.1
MVMSRPSSSLDEIRKAQRADGPAGILAIGTANPANHVLQAEYPDYYFRITNSEHMTDLKEKFKRMCDKSMIRKRHMHLTEEFLKENPNMCAYMAPSLDVRQDIVVVEVPKLGKEAAVKAIKEWGQPKSKITHVVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFSDGASALIVGSDPDASVGEKPIFEMVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLEEAFKPLGISDWNSLFWIAHPGGPAILDEVEKKLGLKAEKMRATRQVLSEYGNMSSACVLFILDEMRRKSAKDGVATTGEGLEWGVLFGFGPGLTVETVVLHSVPV
>rna-XM_013779478.1
MSSSGMNCVEKQITTRRVANPGKATVLALGKAFPSQVVPQEHLVEGFLRDTKCDDPFIKEKLEHLCKTTTVKTRYTVLSREILDKYPELTTEGSPTIKQRLEIANEAVVEMALEASLGCIKEWGRQVEDITHIVYVSSSEIRLPGGDLYLSAKLGLKSDVNRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARSYDLVGAALFGDGAAAVIIGADPLPSEAPFMELHYAVQQFVPGTQNVIDGRLTEEGINFKLGRDLPQKIEENIEEFCKKLMGKAGDDSMEFNDMFWTVHPGGPAILNRLETKLKLGREKLECSRRALVDYGNVSSNTILYVMEYMRDELKKKGDGALEWGLGLAFGPGITFEGLLLRSLASP
>rna-XM_013741176.1
MGSIDATELASEKKPNPGKATILAIGKAFPHQLVMQEYLVDGYFKTTNCDDPELKQKLTRLCKTTTVKTRYVVMSEEILTKYPEIAIEGGSTVKQRLDICNDAVTEMAVEASRSCIKNWGRSVSDITHLVYVSSSEARLPGGDLFLAKGLGLSPETHRVLLYFVGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSKDRPYDLVGVALFGDGAGAMIIGSDPDPVSEKPLFELHTAIQNFLPDTEKTIDGRLTETGINFTLSRELPQIIEDNVESFCKKLIGKAGLADKDYNQMFWAVHPGGPAILNRMEKRLNLSPEKLSPSRRSLMDYGNASSNSIVYVLEYMLEESRKSRSMSGSENEWGLILAFGPGVTFEGIVARNLDV
>rna-XM_013750528.1
MVMGTPSSLDEIRKAQRADGPAGILAIGTANPANHVIQAEYPDYYFRITNSEHMTDLKEKFKRMCDKSTIRKRHMHLTEEFLKENPDMCAYMAPSLDARQDIVVVEVPKLGKEAAVKAIKEWGQPKSKITHVVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEIIAVTFRGPSDTHLDSLVGQALFSDGAAALIVGSDPDTSAGEKPIFEMVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLDEAFKPLGISDWNSLFWIAHPGGPAILDEVEKKLGLKAEKMRATRHVLSEYGNMSSACVLFILDEMRRKSAEDGVATTGEGLEWGVLFGFGPGLTVETVVLHSVPV
>rna-XM_013751442.1
MGTPSSLGEIRKAQRADGPAGILAIGTANPANHVIQAEYPDYYFRITNSEHMIDLKEKFKRMCDKSGIRKRHMHLTEEFLKDNPNMCAYMAPSLDVRQDVVVVEVPKLGKEAAEKAIKEWGQPKSRITHLVFCTTSGVDMPGADYQLTKLLGLCPSVKRLMMYQQGCFAGATVLRLAKDLAENNRGARVLVVCSEIIALFFRGPSDTHLDSLLGQALFSDGAAALVVGSDPDISVGEKPIFEMVSAAQTILPDSDGAINLQLREAGLTFHLLKHVPRLISKNIEKSLHEAFKPLGISDWNSLFWIAHPGGRAIFDEVEKKLGLKAEKMRATRHVLSEYGNMTSACVLFILDEMRRKSAEDGVATTGEGLEWGVLFGFGPGLTVETVVLHSVPL
MVMGALSLDEIRKAQRGDGPASILAIGTANPPNQVIQAEYPDYYFRITNSEHMTDLKEKFKRMCDKSMIRKRYMHLTEEFLKDNPNICAFMAPSLDVRQDILVTEVPKLGKEAAVNAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLIKLLGLSPFVKRVMMYHQGCYAGGTVLRLAKDIAENNRGARVLIVCSEITVVTFRGPSETHLDSLVGQSLFGDGAAALIVGSDPDTSAGEKPIFEMVSAAQTILPDSKGAIEGHLKEVGLTFHLLKTVPGLISKNIEKCLQEAFKPLGISDWNSLFWIAHPGGPAILDHVEIKLGLKAAKMKATRHVLSEYGNMSSACVFFILDEMRRRAVEDGAETTGEGLEWGVLFGFGPGLTVETVVLHSVPL
>rna-XM_013762407.1
MVMGALSLDEIRKAQRADGPASILAIGTANPPNQVTQAEYPDYYFRITNSEHMTDLKEKFKRMCDKSVIRKRYMHLTEEFLKDTPNICAFMAPSLDVRQDILVAEVPKLGKEAAVKAIKEWGQPKSKITHLVFCTTSGVAMPGADYQLIKLLGLCPSVKRVMMYHQGCYAGGTVLRLAKDIAENNRGARVLIICAEITVVTFRGPSETQLDSLVGQSFFGDGTAALIVGSDPDTSVGEKPIFEMVSAAQTILPDSQGAIEGHLKEVALTFHLLKTVPGLISKNIEKCLEEAFKPLGISDWNSLFWIAHPGGPSILDHVEIKLGLKAEKMKATRHVLSEYGNMSSACIIHLNSLRERSQDWNKHILNLDMGYYVNLAMKSNGGGPMNVCRVGKR
>rna-XM_013765981.1
MVMVGTTSSLDEIRKAQRADGPAGILAIGTANPANHVLQAEYPHNYFRITNSAYMTDLKEKFKRMCDKSTIRKRHMHLTEEFLKENPNMCAYMAPSLDARQDLVVVEVPKLGKDAAVKAIKEWGQPKSKITHVVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFSDGAAALIVGSDPDVSAGEKPIFEMVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLDEAFKPLGISDWNSLFWIAHPGGPAILDDVEKKLGLKAEKMRATRHVLSEYGNMSSACVLFILDEMRRKSVEDGVATTGEGLEWGVLFGFGPGLTVETVVLHSVPV
>rna-XM_013768106.1
MGSIDATELGSEKKPNPGKATILAIGKAFPQQLVMQEYLVDGYFKTTNCDDPELKQKLTRLCKTTTVKTRYVVMSEEILNKYPELATEGGSTVKQRLDICNDAVTEMAVEASRACIENWGRSISDITHLVYVSSSEARLPGGDLYLAKGLGLSPETHRVLLYFVGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSADRPYDLVGVALFGDGAGAMIVGSDPDPVREKPLFELHTAIQNFLPDTEKTIDGKLTEQGINFTLSRELPQIIEDNVESFCKKLIGKAGLAHKDYNQMFWAVHPGGPAILNRMEKRLNLSPEKLSPSRRALMDYGNASSNSIVYVLEYMLEESRKARNMNEGGNEWGLILAFGPGVTFEGIVARNIDV
>rna-XM_013771363.1
MLATGRVAKQKEIAQSTRRVANQGKATVLALGKAFPSNVVSQENLVEEYLREIKCDDPSIKEKLQHLCKTTTVKTRYTVMSSETMQKYPELATEGSPTIKQRLEIANEAVVQMAYEASLACIKEWGRGVEDITHLVYVSSSEFRLPGGDLYLSAQLGLSNEVQRVMFYFLGCYGGVSGMRVAKDIAENNPGSRVLLTTSETMVLGFRPPNKARPYDLVGAALFGDGAAALIIGADPTESENPFMELHYALQQFLPGTQGVIDGRLSEEGISFKLGRELPQKIEDNIEEFCKKLVAKAGSGSLELNDLFWAVHPGGPAILNGLETKLKLKPEKLECSRQALVDYGNASSNTIFYIMDKVRGELEKKGRGGEEWGLGLAFGPGITFEGFLMRSL
>rna-XM_013766928.1
MVMSRPSSSLDEIRKAQRADGPAGILAIGTANPANHVLQAEYPDYYFRITNSEHMTDLKEKFKRMCDKSMIRKRHMHLTEEFLKENPNMCAYMAPSLDVRQDIVVVEVPKLGKEAAVKAIKEWGQPKSKITHVVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFSDGASALIVGSDPDASVGEKPIFEMVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLEEAFKPLGISDWNSLFWIAHPGGPAILDEVEKKLGLKAEKMRATRQVLSEYGNMSSACVLFILDEMRRKSAKDGVATTGEGLEWGVLFGFGPGLTVETVVLHSVPV
>rna-XM_013779478.1
MSSSGMNCVEKQITTRRVANPGKATVLALGKAFPSQVVPQEHLVEGFLRDTKCDDPFIKEKLEHLCKTTTVKTRYTVLSREILDKYPELTTEGSPTIKQRLEIANEAVVEMALEASLGCIKEWGRQVEDITHIVYVSSSEIRLPGGDLYLSAKLGLKSDVNRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARSYDLVGAALFGDGAAAVIIGADPLPSEAPFMELHYAVQQFVPGTQNVIDGRLTEEGINFKLGRDLPQKIEENIEEFCKKLMGKAGDDSMEFNDMFWTVHPGGPAILNRLETKLKLGREKLECSRRALVDYGNVSSNTILYVMEYMRDELKKKGDGALEWGLGLAFGPGITFEGLLLRSLASP
>rna-XM_013741176.1
MGSIDATELASEKKPNPGKATILAIGKAFPHQLVMQEYLVDGYFKTTNCDDPELKQKLTRLCKTTTVKTRYVVMSEEILTKYPEIAIEGGSTVKQRLDICNDAVTEMAVEASRSCIKNWGRSVSDITHLVYVSSSEARLPGGDLFLAKGLGLSPETHRVLLYFVGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSKDRPYDLVGVALFGDGAGAMIIGSDPDPVSEKPLFELHTAIQNFLPDTEKTIDGRLTETGINFTLSRELPQIIEDNVESFCKKLIGKAGLADKDYNQMFWAVHPGGPAILNRMEKRLNLSPEKLSPSRRSLMDYGNASSNSIVYVLEYMLEESRKSRSMSGSENEWGLILAFGPGVTFEGIVARNLDV
>rna-XM_013750528.1
MVMGTPSSLDEIRKAQRADGPAGILAIGTANPANHVIQAEYPDYYFRITNSEHMTDLKEKFKRMCDKSTIRKRHMHLTEEFLKENPDMCAYMAPSLDARQDIVVVEVPKLGKEAAVKAIKEWGQPKSKITHVVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEIIAVTFRGPSDTHLDSLVGQALFSDGAAALIVGSDPDTSAGEKPIFEMVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLDEAFKPLGISDWNSLFWIAHPGGPAILDEVEKKLGLKAEKMRATRHVLSEYGNMSSACVLFILDEMRRKSAEDGVATTGEGLEWGVLFGFGPGLTVETVVLHSVPV
>rna-XM_013751442.1
MGTPSSLGEIRKAQRADGPAGILAIGTANPANHVIQAEYPDYYFRITNSEHMIDLKEKFKRMCDKSGIRKRHMHLTEEFLKDNPNMCAYMAPSLDVRQDVVVVEVPKLGKEAAEKAIKEWGQPKSRITHLVFCTTSGVDMPGADYQLTKLLGLCPSVKRLMMYQQGCFAGATVLRLAKDLAENNRGARVLVVCSEIIALFFRGPSDTHLDSLLGQALFSDGAAALVVGSDPDISVGEKPIFEMVSAAQTILPDSDGAINLQLREAGLTFHLLKHVPRLISKNIEKSLHEAFKPLGISDWNSLFWIAHPGGRAIFDEVEKKLGLKAEKMRATRHVLSEYGNMTSACVLFILDEMRRKSAEDGVATTGEGLEWGVLFGFGPGLTVETVVLHSVPL
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University