Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Boehmeria nivea
Species name
Chinese silk-plant (Boehmeria nivea) is a species of eudicot in the family Urticaceae (nettle family).
Species info
Gene sequence info
Boehmeria_nivea.HIDH.fa
Download
>Bni01T001081.1
MSIVEEAPGYIQVFSDGSVKRFAPETASASDQETSLNGLNFKSKDVIIDPSKPITARIFLPENTPSSTDSLLPLLVYFHGGGFCIGSTTWLGYHRFLGDLSAALRCVVVSVDYRLAPENRLPAAYEDGCTALDWISTSVRGRSSEPWLDGADLSRVFLSGDSAGGNIAHNVAVRTAIAGLEGVKIAGLLLVHPYFGSEERTEREAAAKGAERDVVAMNDMREGAGAESEAPLRWREFPAVAVFVAGRDFLKERGVMYARFLERNGVGDVRLVEAEDECHVFHVFYPESEATRLLQRQMSEFINSAGY
>Bni01T001504.3
MGSASPEVSIDAFPFLRLYTDGTIERLAGTHVAPAGLDPQTGVVSKDVVVSPETGVTARLYLPEVAGREKKLPLAVYFHGGGFFISSTADPVYHNGLNRLASAAQIAVVSVNYRLAPETPLPAAYDDCYAALRWLGSASGGRAEPWLRDAGGRAEPWLRDGADFSRVVLLGDSAGASIAHSLACRLSESDPNPGFTLSGAALIHPYFWGSERVGSEIRDVARSEMVDRWWKVVCPSEKGNDDPLINPFAAGAPSLAGLKSCPRILVLVAGSDILRERGWVYYERVVKSSEFNGKIEIVETEGEDHIFHILCPDSDKAEGLVKCLADFVNQV
>Bni02T002243.1
MSSATTAAAASPPYEVDECRGVLRVYSDGSVVRSASPSFDVPVRDDGSVAWKDLVFDPLHGLSLRLYRPTSAAATDAPLPIFFYIHGGGFCIGSRAWPNCQNYCLRLAAELGALVVSPDYRLAPENRLPAAIEDGFAALKWLRAQAEAAEPADEWLSRGAADYGRVFVSGDSAGGNIAHNAAVWLGAGSAELGAAVRVRGYVLLAPFFGGTVRTKSEAEGPKDAFLNLELIDRFWRLSIPIGETTDHPLVNPFGPLSKSLEEVALDPTLVVVGGSDLLKDRAQIYATKLKSYGKKIDYVEFQGKQHGFFTIDPHSEDSNKLMVIIKSFIAENSK
>Bni04T006080.4
MRFRKSKMATIPMDPQFNQHSRHQHGGGAVAEEIKGLIRVSKDGHVERPPIVPIVPCSSIPPSLDVTCKDVYIDKLTSLWARVYAPNAAAAPEPLPLLVYFHGGGFCVGSAAWSCYHDFLAAVASKAGCVVVSVNYRLAPESCLPAAYEDGLAALLWIKQQAACPSGENRFWLSRCDVSNAFLAGDSAGANIAFHVAERGGAAKGLVLIQPFFGGEARTASERHSAQPPGSALTLAASDAYWRLALPPGAGRDHPWCNPLGAAAGRLREALARVPRVMVCVAETDILRDRNVELCNALAAAGKKVNMVMYRGVGHAFQVLHNSPFAQARTREMLSHIKSFISQ
>Bni06T009544.1
MDSEAEIAFEFSPYFLGIQRRTCRKILRHRRRASWDRSTRRSFLQRRADLLGDRRVGACFCADGRRPRGKLPLLVYFHGGAFLVGSPFCPTYHNFVSSLLMKTRGPLKWVASHDDASGPEPVLNERVDWARVFLGGDSVGGNIVHNMVAQAGEEQPGEKMRLLGACLVHPYFSNREGGDVDKTWKFACPTAVGSGDPRINPKLDPRMARIGCGKVLICLAELDGLRENGIFYYETLIESGWDGDVAIFETKGESHVFHLFNPNCDKALALIKRDIILQQGTKNMHPDLSPLLKVHKDGRVERLLGTATVPASLDPATGVGSLDLVICPETGLSARLYAPEQQQHTADRMPQKLRPLLVYFHGGGFVIESAFSATYHGYLTALAARADAVVLSVDYRLAPEHPLPAAYDDAWVALKWVASRAASDPWLAPRRADRARVYVAGDSAGGNIAHHVAVRAGTEGGLEGVELRGAALIHPYFWGSEPIGNEAAAEKAGGKALVEKLWRFTCPDTRGADHPWINPEKDPDLGPLGCGRVVVFVAEKDALRDRGRRYGEVLEKLKGSGWGGTVEVVEDMGEDHVFHLFKPGCDKAVVMMGKICNFINQDA
>Bni06T009545.1
FVFYYQTLQLLLILSYINKSLIIPRRRNLCSELTHIQKMVPISTDQIAFEIPQRFRIYKDGRVDRFFGNETIPPFTDPQTGVQSKDIILSPESGLSARIFPPRVTDPTQKIPVLVFIHGGAFCLQTPFSPIFHGHVSTLAARSGVVAVSIHYRRAPEHPLPVAFDDSWAATEWAAAHRGGDGPEAWLNDHADLGRVFVMGDSLWATLAHHVVRRAGVDGLGGLRITGLVAIHPFFEKEGPEPDKLLDVIFPTRSKTGDPRVHPGQDPELGRLGCGKVLVCLAEKDHLRERGWAYYEALKKSGWAGHLEVFESQGEQHVFHLFNPTCHNAVALMNKVPRRNLCSEFKPTQKMDPISADQIAFDFPNLFRIYKDGRIDRFDGTETIPPFTDPKTGVQSKDIIISPETGLSARVFMPLISDPTRRLPLLVFIHGGAFCIQTPFSRIYHSHVGTLAAMSDVVAVSVHYGRAPEHPLPIAFEDSWAAIQYIAAHRDGAGPEAWLNNHVDLGRVFVGGDSAGGTLAHYVTRRAGVAGLCGLRIIGLVAIHPFFHTDGVGSDQLLDIIFPTRAGSGDPRVNPIRDPDLGRLGCEKVLICVAEKDSLRERGWAYYEALKNSGWAGSLEVFESQGEDHVFHLFNPTCDNAVAFMNKVLNLTTTMEEQSEVVIEFQYFRIYKDGRIDRLLGEEIVPPSPEAESGVRSKDVVVSPESGLSARLFLPEMTDPTRRVPLVVFLHDGAFCIETPFSPRYHRHGVALASDADAVVLSVHYRRAPEHPLPIAFDDTWDALRWAASHVGGTGPEAWLNDRVDFGRVFLVGASAGATLAHYAARRAGLEGGPSGLRIFGKARVLVFVAEKDFLKDRGLAYYEALKTSEWKGKVEIVESKGEDHILSICSIPIGNPSPLRGKAGRVGGRAKWAAYLWGGSGPPVFFGNDQPDKLIQFIYPTSTVLGDPKLNPGMDPELGRLWCGRVLRLGLFYEALKKSEWKGKVEIVESKVEEDHTFHLFNPNSENAVALMNKHFSFIEELNLTTTMEEQSEVVIEFQYFRIYKDGRIDRLLGEEIVPPSPEAESGVRSKDVVVSPESGLSARLFLPEMPDPTRRVPLVVFLHGGAFCIETPFSPRYHRHGVDLAADADAIILSVHYRRAPEHPLPIAYDDTWDALRWTASHVGGTGPEAWLNDHVDFGRVFLVGASAGATLAHYAARRAGLEGGPSGLHIFGVVLVHPFFGNDQPDKLIQFIYPTNTGSGDPKLNPDMDPELGRLGCGRVLVFVAEKDFLKDRGLAYYEALKKSEWKGKVEIVESKGEDHTFHLFNPSSENAIALMNKLDGRIDRLLGEETVPQSPDGDESGVRSKDVVLSPESGLSARIFLPKSADPTRKLPFLVYFHGGAFCAGNPFSVIYSGHVAALSAEANAVVLSVHYRRAPEHPLPIAYNDALEALKWASAHFNGSGPDPWVNEHADLVRLFVGGDSAGANIAHNAVMRAGLDGPDGPRIAGLLLVHPFFGNEEVDKLLEIIFPSSTGPGDPRVTPGHDPELGRLGCERVLVFVAEKDHLRDRGVSYYEALRNSGWAGSAEVVEELGERHVFHLLDPKSEKAGALVKRAASFSKTADDIIHEFRFFRVHKDGRVTLRFPHSPNVPPSEDHPVNGVRSKDVIISADPRVTARVFLPARPGVKLPVLLYVHGGGFCMQSPFTRTYNDFVATVAGASGAVAVSVDYGLFPARPMPACYDDSWAALRWIAAHAGGAGPEPWLNSHADLGRVFIAGDSAGGNMTHDLVTRVGRVGLPGLTVAGACLIHPYFGGTEDDHMVMYMFPENKGRGDPRISPAAEDLAGIGCGKVLVFVAEKDSLVGPGKRYAEDLREILPFNNTLYHSSISPFPKRKRRTSILFPFHSLKPLQITCTNSTSTTSTEMATISPSQEVAQDFSPFLKIYKDGHIERLVGIDVVPPSLDPETGVESKDVVISPDTGVSARLYVPRGSPDAGGGRKLPLVVYFHGGGFCVETPFCAKYDHAVKTLVAEANVVAVSVDYRLAPENPIPIPYDDSWAAVEWAVAHAGGAGPDEWLNGRADFRRVYFAGDSAGANIAHNAALRVGTAGFPTEGANLAGIVLVHPYFWGLEPIGDEPREPEKRAMAEGIWRFAYPGTTAGSDDPWMNPAKDPDLGRLGCGRVLVCVAEKDGLRDRAWYYKEVLEKSGWVGNVEVFEAKGDDHVFHLSNPTCDNAVALVKKIASFVNDEEN
MSIVEEAPGYIQVFSDGSVKRFAPETASASDQETSLNGLNFKSKDVIIDPSKPITARIFLPENTPSSTDSLLPLLVYFHGGGFCIGSTTWLGYHRFLGDLSAALRCVVVSVDYRLAPENRLPAAYEDGCTALDWISTSVRGRSSEPWLDGADLSRVFLSGDSAGGNIAHNVAVRTAIAGLEGVKIAGLLLVHPYFGSEERTEREAAAKGAERDVVAMNDMREGAGAESEAPLRWREFPAVAVFVAGRDFLKERGVMYARFLERNGVGDVRLVEAEDECHVFHVFYPESEATRLLQRQMSEFINSAGY
>Bni01T001504.3
MGSASPEVSIDAFPFLRLYTDGTIERLAGTHVAPAGLDPQTGVVSKDVVVSPETGVTARLYLPEVAGREKKLPLAVYFHGGGFFISSTADPVYHNGLNRLASAAQIAVVSVNYRLAPETPLPAAYDDCYAALRWLGSASGGRAEPWLRDAGGRAEPWLRDGADFSRVVLLGDSAGASIAHSLACRLSESDPNPGFTLSGAALIHPYFWGSERVGSEIRDVARSEMVDRWWKVVCPSEKGNDDPLINPFAAGAPSLAGLKSCPRILVLVAGSDILRERGWVYYERVVKSSEFNGKIEIVETEGEDHIFHILCPDSDKAEGLVKCLADFVNQV
>Bni02T002243.1
MSSATTAAAASPPYEVDECRGVLRVYSDGSVVRSASPSFDVPVRDDGSVAWKDLVFDPLHGLSLRLYRPTSAAATDAPLPIFFYIHGGGFCIGSRAWPNCQNYCLRLAAELGALVVSPDYRLAPENRLPAAIEDGFAALKWLRAQAEAAEPADEWLSRGAADYGRVFVSGDSAGGNIAHNAAVWLGAGSAELGAAVRVRGYVLLAPFFGGTVRTKSEAEGPKDAFLNLELIDRFWRLSIPIGETTDHPLVNPFGPLSKSLEEVALDPTLVVVGGSDLLKDRAQIYATKLKSYGKKIDYVEFQGKQHGFFTIDPHSEDSNKLMVIIKSFIAENSK
>Bni04T006080.4
MRFRKSKMATIPMDPQFNQHSRHQHGGGAVAEEIKGLIRVSKDGHVERPPIVPIVPCSSIPPSLDVTCKDVYIDKLTSLWARVYAPNAAAAPEPLPLLVYFHGGGFCVGSAAWSCYHDFLAAVASKAGCVVVSVNYRLAPESCLPAAYEDGLAALLWIKQQAACPSGENRFWLSRCDVSNAFLAGDSAGANIAFHVAERGGAAKGLVLIQPFFGGEARTASERHSAQPPGSALTLAASDAYWRLALPPGAGRDHPWCNPLGAAAGRLREALARVPRVMVCVAETDILRDRNVELCNALAAAGKKVNMVMYRGVGHAFQVLHNSPFAQARTREMLSHIKSFISQ
>Bni06T009544.1
MDSEAEIAFEFSPYFLGIQRRTCRKILRHRRRASWDRSTRRSFLQRRADLLGDRRVGACFCADGRRPRGKLPLLVYFHGGAFLVGSPFCPTYHNFVSSLLMKTRGPLKWVASHDDASGPEPVLNERVDWARVFLGGDSVGGNIVHNMVAQAGEEQPGEKMRLLGACLVHPYFSNREGGDVDKTWKFACPTAVGSGDPRINPKLDPRMARIGCGKVLICLAELDGLRENGIFYYETLIESGWDGDVAIFETKGESHVFHLFNPNCDKALALIKRDIILQQGTKNMHPDLSPLLKVHKDGRVERLLGTATVPASLDPATGVGSLDLVICPETGLSARLYAPEQQQHTADRMPQKLRPLLVYFHGGGFVIESAFSATYHGYLTALAARADAVVLSVDYRLAPEHPLPAAYDDAWVALKWVASRAASDPWLAPRRADRARVYVAGDSAGGNIAHHVAVRAGTEGGLEGVELRGAALIHPYFWGSEPIGNEAAAEKAGGKALVEKLWRFTCPDTRGADHPWINPEKDPDLGPLGCGRVVVFVAEKDALRDRGRRYGEVLEKLKGSGWGGTVEVVEDMGEDHVFHLFKPGCDKAVVMMGKICNFINQDA
>Bni06T009545.1
FVFYYQTLQLLLILSYINKSLIIPRRRNLCSELTHIQKMVPISTDQIAFEIPQRFRIYKDGRVDRFFGNETIPPFTDPQTGVQSKDIILSPESGLSARIFPPRVTDPTQKIPVLVFIHGGAFCLQTPFSPIFHGHVSTLAARSGVVAVSIHYRRAPEHPLPVAFDDSWAATEWAAAHRGGDGPEAWLNDHADLGRVFVMGDSLWATLAHHVVRRAGVDGLGGLRITGLVAIHPFFEKEGPEPDKLLDVIFPTRSKTGDPRVHPGQDPELGRLGCGKVLVCLAEKDHLRERGWAYYEALKKSGWAGHLEVFESQGEQHVFHLFNPTCHNAVALMNKVPRRNLCSEFKPTQKMDPISADQIAFDFPNLFRIYKDGRIDRFDGTETIPPFTDPKTGVQSKDIIISPETGLSARVFMPLISDPTRRLPLLVFIHGGAFCIQTPFSRIYHSHVGTLAAMSDVVAVSVHYGRAPEHPLPIAFEDSWAAIQYIAAHRDGAGPEAWLNNHVDLGRVFVGGDSAGGTLAHYVTRRAGVAGLCGLRIIGLVAIHPFFHTDGVGSDQLLDIIFPTRAGSGDPRVNPIRDPDLGRLGCEKVLICVAEKDSLRERGWAYYEALKNSGWAGSLEVFESQGEDHVFHLFNPTCDNAVAFMNKVLNLTTTMEEQSEVVIEFQYFRIYKDGRIDRLLGEEIVPPSPEAESGVRSKDVVVSPESGLSARLFLPEMTDPTRRVPLVVFLHDGAFCIETPFSPRYHRHGVALASDADAVVLSVHYRRAPEHPLPIAFDDTWDALRWAASHVGGTGPEAWLNDRVDFGRVFLVGASAGATLAHYAARRAGLEGGPSGLRIFGKARVLVFVAEKDFLKDRGLAYYEALKTSEWKGKVEIVESKGEDHILSICSIPIGNPSPLRGKAGRVGGRAKWAAYLWGGSGPPVFFGNDQPDKLIQFIYPTSTVLGDPKLNPGMDPELGRLWCGRVLRLGLFYEALKKSEWKGKVEIVESKVEEDHTFHLFNPNSENAVALMNKHFSFIEELNLTTTMEEQSEVVIEFQYFRIYKDGRIDRLLGEEIVPPSPEAESGVRSKDVVVSPESGLSARLFLPEMPDPTRRVPLVVFLHGGAFCIETPFSPRYHRHGVDLAADADAIILSVHYRRAPEHPLPIAYDDTWDALRWTASHVGGTGPEAWLNDHVDFGRVFLVGASAGATLAHYAARRAGLEGGPSGLHIFGVVLVHPFFGNDQPDKLIQFIYPTNTGSGDPKLNPDMDPELGRLGCGRVLVFVAEKDFLKDRGLAYYEALKKSEWKGKVEIVESKGEDHTFHLFNPSSENAIALMNKLDGRIDRLLGEETVPQSPDGDESGVRSKDVVLSPESGLSARIFLPKSADPTRKLPFLVYFHGGAFCAGNPFSVIYSGHVAALSAEANAVVLSVHYRRAPEHPLPIAYNDALEALKWASAHFNGSGPDPWVNEHADLVRLFVGGDSAGANIAHNAVMRAGLDGPDGPRIAGLLLVHPFFGNEEVDKLLEIIFPSSTGPGDPRVTPGHDPELGRLGCERVLVFVAEKDHLRDRGVSYYEALRNSGWAGSAEVVEELGERHVFHLLDPKSEKAGALVKRAASFSKTADDIIHEFRFFRVHKDGRVTLRFPHSPNVPPSEDHPVNGVRSKDVIISADPRVTARVFLPARPGVKLPVLLYVHGGGFCMQSPFTRTYNDFVATVAGASGAVAVSVDYGLFPARPMPACYDDSWAALRWIAAHAGGAGPEPWLNSHADLGRVFIAGDSAGGNMTHDLVTRVGRVGLPGLTVAGACLIHPYFGGTEDDHMVMYMFPENKGRGDPRISPAAEDLAGIGCGKVLVFVAEKDSLVGPGKRYAEDLREILPFNNTLYHSSISPFPKRKRRTSILFPFHSLKPLQITCTNSTSTTSTEMATISPSQEVAQDFSPFLKIYKDGHIERLVGIDVVPPSLDPETGVESKDVVISPDTGVSARLYVPRGSPDAGGGRKLPLVVYFHGGGFCVETPFCAKYDHAVKTLVAEANVVAVSVDYRLAPENPIPIPYDDSWAAVEWAVAHAGGAGPDEWLNGRADFRRVYFAGDSAGANIAHNAALRVGTAGFPTEGANLAGIVLVHPYFWGLEPIGDEPREPEKRAMAEGIWRFAYPGTTAGSDDPWMNPAKDPDLGRLGCGRVLVCVAEKDGLRDRAWYYKEVLEKSGWVGNVEVFEAKGDDHVFHLSNPTCDNAVALVKKIASFVNDEEN
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University