Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Boehmeria nivea
Species name
Chinese silk-plant (Boehmeria nivea) is a species of eudicot in the family Urticaceae (nettle family).
Species info
Gene sequence info
Boehmeria_nivea.4CL.fa
Download
>Bni12T017204.1
MAKCFDPPTNTFFSPRPPIDFPVDRSLSLTALLFRSSASRRLDTALIDDDSGESLTFLELEALVAKLSHALRNRLGVGKNDVVLIFAPNSIYFPVFFLAVAAIGAITTTCNPSYTFFELSKQVKDSKPKLVVTVAELFEKVESFDLPSIILPSPPSTIVKPGSKTLSFSELVETTPDVNLPESDVSQDDVAALLYSSGTTGTSKGVVLTHRNFITTSFMVTSDQDRFGEPRNVFLCFLPMFHIFGLSVIAYSQLRRGNALVSMAKFDFERALRAVEKYRVTHLYLVPPVAIALAKNGDAVRRFDLSSLRVILSGAAPLGRDVMEGCAKNMPSVKITQVSSSRELSSLGPQSRWSLPLSGLMTKECHVIGLFSKGYGMTETCGIVSLEDSREGSRFSGSAGHLAPGIIARITNVETLKPLPPNQLGEVWVKGPNMMQGYFNNPEATNSTIDEQGWVHTGDLGYFDEVGQLFVVDRIKELIKCYGFQVAPAELEGLLLSHPEIVDAVVIPFPDEKAGEVPIAYIVRAPNSSLTEEDVQRFVEKQVAPFKRLRRVTFVSSVPKSVSGKILRRELIQKVRSKI
>Bni13T017586.3
TKSGKQRKNNNPNPFPNTTLPNSKLIHFSLSFSLEPNTTKKMGHQANHDDHEFIFRSKLPDIYIPNHLPLHSYCFEHIAQFKDRPCLIDGPTGETYTYAEVELTSRKVAAGLDRLGIKQGDVIMLLLPNCPEFVFAFLGASFLGAISTTANPFYTPAEIAKQAVAAKARLIVTLAAYVEKIRPFAEENSVRIVCVDEAAAEDCVRFAELTGADEAEIPPVKISPEDAVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFRSDDVILCVLPLFHIYSLNSILLCGLRVGAGILIMPRYDIARLLELVERYGVTIAPFVPPIVLAIAKSPELERYDLSSIRTVMSGGAPMGKELEDAVKERLPHAKLGQGYGMTEAGPVLSMCLAFAKEPFPIKSGACGTVVRNAEMKIVDPDTGASLPRNQAGEICIRGNQIMKGYINDPKATKETIDEGGWLHTGDIGYIDDDDEIFIVDRLKELIKVRGFQVAPAELEALLVAHPNISDAAVVPMKDENAGEIPVAFVVRSNGSKITEEAIKKYISDQVVYYKRIGRVFFIDKIPKSPSGKILRKDLRAKVATEVAN
>Bni02T003142.1
MERSGFARDGVFRSLRPPLVLPKDTSLSLVSFLFRHCSSYPNKPALIDADSSDTLSFSQLRTLSAKLAHSFLTIGVAKNDVVLIFAPNSIHFLACFLGAVAAGAIVTTANPLYTVAELSKQVKDSKPKLVITVPQLWDKVKGFDLPTLILGSPKPQAHKNAMSFDDFVSLSGSASEFPSVDIRQNDTAVLLYSSGTTGMSKGVVLTHRNFISASTMVTMDQEIAGEKHNVFLCVLPMFHVFGLTVISYAQLQRGNAVVSMARFDLQKILSAVERYRITHLWVVPPIVLALAKSGVVSKYDLSSLRHIGSGAAPLGKELMEECAKIIPHCVIAQGYGMTETCGVVSFEDTRGGKRNSGSAGTLVSGVEAQIMSVETSKPLPPKQLGEIWVRGPNMMQGYFNNVEATKLTIDKKGWVHTGDLGYFDEDGHLYVVDRIKELIKYKGFQVAPAELEGLLISHPEILDAVVIPFPDAEAGEVPVAYVVRSPSSSLTEDDVKKFIADQVAPFKRLRRVTFVNSVPKSASGKILRRELIEKVRSKI
>Bni03T005097.1
MITVASSVEAQKPADIAPTTTTTTQHEQQQEQEHRQNISPTGTGTGTSHIFKSKFPDIQISNHLPLHTYCFERMSEYADRPCLISGATGKTYTYAETHLASRKAAAGLSGVGIGRGDAIMILLPNCEEFVISFVAASMLGAVTTTANPYYTAAEISKQLAASKSKLIITQSQYVDKLRDIVDIGDNFKVITTDAPPEKCLHFSVLSEADEINAPEVTIQPDDPVALPFSSGTTGLPKGVVLTHKSLVTSVAQQVDGENPNLYLTPNDVVLCVLPLFHIYSLNSVLLCSLRAGAAVLLMQKFEIGALLTLIQRHRVSMAAVVPPLVLALAKNPTVADFDLSSIRIVLSGAAPLGKELEDALRSRVPQAILGQGYGMTEAGPVLSMSPSFAKQPLPTKSGSCGSVVRNAELKVVDPETACSLSYNQPGEICIRGDQIMKGYLNDDKATAATIDSEGWLHTGDIGYVDDDNEVFIVDRVKELIKFKGFQVPPAELEALLLSHPSIADAAVVPQKDDVAGEVPVAFVVRSNGFDLTEEAVKEFIAKQVVFYKKLHKVYFVHAIPKSPSGKILRKDLRAKLATPSPSSP
>Bni06T008449.1
MNPYDRPCLIDGPTGVTYTFAEDQARRRDHAPSPEFVFAFLGAISTTANPCYTPTEIAKQAAAAKAKLFVSSV
>Bni07T010889.1
MRQSDTAAIMYSSGTTGTSKGVVLSHGNLIAMVELFVRFEASQYSASASEAVYLAVLPMFHIYGLSLFAVGLLSLGATIVVMSKKFDVEEVAEAVERFGVTHFPVVPPILAALARRDDASPRRWRRLQSLKQVSSGAAPLSAKAIEDFVMALPDVDFIQGYGMTESTAVGTRGFNTKKFKNFSSVGLLAPNMEAKVVDWTTGSFLPPGSSGELWLRGPAIMKGYLNNKAETMATINKDGWLRTGDIVYFDQDGYLYVVDRLKEIIKYKGFQIAPADLEAVLASHSEISDVAVAAVADEDSGEIPVAFVVRKNGSSLSEETVIDYVARQVSPYKKIRKVVFTPSIPRSAAGKILRRELRKSLSSKL
>Bni09T013145.2
SLHQPHPIKTKHTKIPSSYIPVTSLAPLLGALILITSNTIKHITNCSKTPPKKKKKKNHFSQIVLAMAEAESINNHKQQDIIFRSKLPDIFIPKELPLHTYCLGNKSPEGAQRPCLINGPTGEVYTYAEVDAGARRVASGLNKLGVGKGDVVMVLLPNCPEFVLTFLGASYRGAVTTAANPFFTPAEILKQAKASGAKLVVTMASYYDKVKDIKVNENEDMVIVCIDTPVPEGCVHFSAVSGADEREMPEAEIEPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLHYSQNDVVLCVLPLFHIYSLNSVLLCGLRAGAAVLIMPKFEIGALLALVERHRVSVAPIVPPIVLAIARHPGLDAHDLSSLRVLKSGGAPLGKELEDTVRAKFPNVTLGQGYGMTEAGPVLTMSLAFAKEPFEVKAGACGTVVRNAEMKIVDPETGSSLPRNQPGEICIRGDQIMKGYLNNREATQNTIDKEGWLHTGDIGFVDDDDELFIVDRLKELIKYKGFQVAPDELEALLLTHPKISDAAVVPMKDEATGEVPVAFVVKSKDSEVTEDEIKQFISKQVVFYKRINRVFFIEAIPKSPSGKILRKDLRAILASGVYQ
>Bni09T013841.1
MANNTSNIAADEEHIFRSRHPAVQVPDDVTLPEFVLQGSEELYAEKVAFVEAVTGKAYTHGEVARKTRRFAGALRSLGLRKGHVVVVVLPNVAEYAIVALGIMAAGCVFSGSNPAGHVSEIKKQVEAAAARLVVTDGPNYEKSFSIFRAKLNFQLHLVACDKEQVKGLEIPVITVDEEPVEGAINWDKLLDAADRAGGARERQLVIRQSDLCALPFSSGTTGVSKGVMLTHRNLVANLCSSLFAVTPEMVGQVTVLGLMPFFHIYGITGICCATLRSKGTVVVMGRYDLRTFLAALIKYEVTFAPIVPPIISDMVHKPAVAEFDLARLKLQSVMSAAAPLAPELLRTFEAKFPGVHVQEAYGLTEHSCITLTHGDPDDKSYSRSAKKNSVGFILPNLEVKFIDPETGRSLPKNTPGELCVRSQCVMQGYYNNKEETDRAIDKEGWLHTGDIAYIDDDGDIFIVDRIKEMIKFKGFQVAPAELEAILLTHPSVEDAAVFPMADEEAGEIPAACVVVAHDAKETEEDILSYVASNVAHYKKIRVLQFVDSIPKSPSGKIMRRLLKDAARLKFAKK
>BniUnT019333.1
MGHQANHDDQEFIFRSKLPDIYIPNHLPLHSYCFEHIAQFKDRPCLIDGPTGETYTYAEVELTSRKVAAGLDRLGIKQGDVIMLLLPNCPEFVFAFLGASFLGAISTTANPFYTPAEIAKQAVAAKARLIVTLAAYVEKIRAFAEENSVRVVCVDEAAADDCVRFAELTGADEAEIPPVKISPEDAVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFRSDDVILCVLPLFHIYSLNSILLCGLRVGAGILIMPRYDIARLLELVERYGVTIAPFVPPIVLAIAKSPELERYDLSSIRTVMSGGAPMGKELEDAVKERLPHAKLGQGYGMTEAGPVLSMCLAFAKEPFPIKSGACGTVVRNAEMKIVDPDTGASLPRNQAGEICIRGNQIMKGYINDPKATKETIDEGGWLHTGDIGYIDDDDEIFIVDRLKELIKVRGFQVAPAELEALLVAHPNISDAAVVPMKDENAGEIPVAFVVRSNGSKITEEAIKKYISDQVVYYKRIGRVFFIDKIPKSPSGKILRKDLRAKVATEVAN
MAKCFDPPTNTFFSPRPPIDFPVDRSLSLTALLFRSSASRRLDTALIDDDSGESLTFLELEALVAKLSHALRNRLGVGKNDVVLIFAPNSIYFPVFFLAVAAIGAITTTCNPSYTFFELSKQVKDSKPKLVVTVAELFEKVESFDLPSIILPSPPSTIVKPGSKTLSFSELVETTPDVNLPESDVSQDDVAALLYSSGTTGTSKGVVLTHRNFITTSFMVTSDQDRFGEPRNVFLCFLPMFHIFGLSVIAYSQLRRGNALVSMAKFDFERALRAVEKYRVTHLYLVPPVAIALAKNGDAVRRFDLSSLRVILSGAAPLGRDVMEGCAKNMPSVKITQVSSSRELSSLGPQSRWSLPLSGLMTKECHVIGLFSKGYGMTETCGIVSLEDSREGSRFSGSAGHLAPGIIARITNVETLKPLPPNQLGEVWVKGPNMMQGYFNNPEATNSTIDEQGWVHTGDLGYFDEVGQLFVVDRIKELIKCYGFQVAPAELEGLLLSHPEIVDAVVIPFPDEKAGEVPIAYIVRAPNSSLTEEDVQRFVEKQVAPFKRLRRVTFVSSVPKSVSGKILRRELIQKVRSKI
>Bni13T017586.3
TKSGKQRKNNNPNPFPNTTLPNSKLIHFSLSFSLEPNTTKKMGHQANHDDHEFIFRSKLPDIYIPNHLPLHSYCFEHIAQFKDRPCLIDGPTGETYTYAEVELTSRKVAAGLDRLGIKQGDVIMLLLPNCPEFVFAFLGASFLGAISTTANPFYTPAEIAKQAVAAKARLIVTLAAYVEKIRPFAEENSVRIVCVDEAAAEDCVRFAELTGADEAEIPPVKISPEDAVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFRSDDVILCVLPLFHIYSLNSILLCGLRVGAGILIMPRYDIARLLELVERYGVTIAPFVPPIVLAIAKSPELERYDLSSIRTVMSGGAPMGKELEDAVKERLPHAKLGQGYGMTEAGPVLSMCLAFAKEPFPIKSGACGTVVRNAEMKIVDPDTGASLPRNQAGEICIRGNQIMKGYINDPKATKETIDEGGWLHTGDIGYIDDDDEIFIVDRLKELIKVRGFQVAPAELEALLVAHPNISDAAVVPMKDENAGEIPVAFVVRSNGSKITEEAIKKYISDQVVYYKRIGRVFFIDKIPKSPSGKILRKDLRAKVATEVAN
>Bni02T003142.1
MERSGFARDGVFRSLRPPLVLPKDTSLSLVSFLFRHCSSYPNKPALIDADSSDTLSFSQLRTLSAKLAHSFLTIGVAKNDVVLIFAPNSIHFLACFLGAVAAGAIVTTANPLYTVAELSKQVKDSKPKLVITVPQLWDKVKGFDLPTLILGSPKPQAHKNAMSFDDFVSLSGSASEFPSVDIRQNDTAVLLYSSGTTGMSKGVVLTHRNFISASTMVTMDQEIAGEKHNVFLCVLPMFHVFGLTVISYAQLQRGNAVVSMARFDLQKILSAVERYRITHLWVVPPIVLALAKSGVVSKYDLSSLRHIGSGAAPLGKELMEECAKIIPHCVIAQGYGMTETCGVVSFEDTRGGKRNSGSAGTLVSGVEAQIMSVETSKPLPPKQLGEIWVRGPNMMQGYFNNVEATKLTIDKKGWVHTGDLGYFDEDGHLYVVDRIKELIKYKGFQVAPAELEGLLISHPEILDAVVIPFPDAEAGEVPVAYVVRSPSSSLTEDDVKKFIADQVAPFKRLRRVTFVNSVPKSASGKILRRELIEKVRSKI
>Bni03T005097.1
MITVASSVEAQKPADIAPTTTTTTQHEQQQEQEHRQNISPTGTGTGTSHIFKSKFPDIQISNHLPLHTYCFERMSEYADRPCLISGATGKTYTYAETHLASRKAAAGLSGVGIGRGDAIMILLPNCEEFVISFVAASMLGAVTTTANPYYTAAEISKQLAASKSKLIITQSQYVDKLRDIVDIGDNFKVITTDAPPEKCLHFSVLSEADEINAPEVTIQPDDPVALPFSSGTTGLPKGVVLTHKSLVTSVAQQVDGENPNLYLTPNDVVLCVLPLFHIYSLNSVLLCSLRAGAAVLLMQKFEIGALLTLIQRHRVSMAAVVPPLVLALAKNPTVADFDLSSIRIVLSGAAPLGKELEDALRSRVPQAILGQGYGMTEAGPVLSMSPSFAKQPLPTKSGSCGSVVRNAELKVVDPETACSLSYNQPGEICIRGDQIMKGYLNDDKATAATIDSEGWLHTGDIGYVDDDNEVFIVDRVKELIKFKGFQVPPAELEALLLSHPSIADAAVVPQKDDVAGEVPVAFVVRSNGFDLTEEAVKEFIAKQVVFYKKLHKVYFVHAIPKSPSGKILRKDLRAKLATPSPSSP
>Bni06T008449.1
MNPYDRPCLIDGPTGVTYTFAEDQARRRDHAPSPEFVFAFLGAISTTANPCYTPTEIAKQAAAAKAKLFVSSV
>Bni07T010889.1
MRQSDTAAIMYSSGTTGTSKGVVLSHGNLIAMVELFVRFEASQYSASASEAVYLAVLPMFHIYGLSLFAVGLLSLGATIVVMSKKFDVEEVAEAVERFGVTHFPVVPPILAALARRDDASPRRWRRLQSLKQVSSGAAPLSAKAIEDFVMALPDVDFIQGYGMTESTAVGTRGFNTKKFKNFSSVGLLAPNMEAKVVDWTTGSFLPPGSSGELWLRGPAIMKGYLNNKAETMATINKDGWLRTGDIVYFDQDGYLYVVDRLKEIIKYKGFQIAPADLEAVLASHSEISDVAVAAVADEDSGEIPVAFVVRKNGSSLSEETVIDYVARQVSPYKKIRKVVFTPSIPRSAAGKILRRELRKSLSSKL
>Bni09T013145.2
SLHQPHPIKTKHTKIPSSYIPVTSLAPLLGALILITSNTIKHITNCSKTPPKKKKKKNHFSQIVLAMAEAESINNHKQQDIIFRSKLPDIFIPKELPLHTYCLGNKSPEGAQRPCLINGPTGEVYTYAEVDAGARRVASGLNKLGVGKGDVVMVLLPNCPEFVLTFLGASYRGAVTTAANPFFTPAEILKQAKASGAKLVVTMASYYDKVKDIKVNENEDMVIVCIDTPVPEGCVHFSAVSGADEREMPEAEIEPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLHYSQNDVVLCVLPLFHIYSLNSVLLCGLRAGAAVLIMPKFEIGALLALVERHRVSVAPIVPPIVLAIARHPGLDAHDLSSLRVLKSGGAPLGKELEDTVRAKFPNVTLGQGYGMTEAGPVLTMSLAFAKEPFEVKAGACGTVVRNAEMKIVDPETGSSLPRNQPGEICIRGDQIMKGYLNNREATQNTIDKEGWLHTGDIGFVDDDDELFIVDRLKELIKYKGFQVAPDELEALLLTHPKISDAAVVPMKDEATGEVPVAFVVKSKDSEVTEDEIKQFISKQVVFYKRINRVFFIEAIPKSPSGKILRKDLRAILASGVYQ
>Bni09T013841.1
MANNTSNIAADEEHIFRSRHPAVQVPDDVTLPEFVLQGSEELYAEKVAFVEAVTGKAYTHGEVARKTRRFAGALRSLGLRKGHVVVVVLPNVAEYAIVALGIMAAGCVFSGSNPAGHVSEIKKQVEAAAARLVVTDGPNYEKSFSIFRAKLNFQLHLVACDKEQVKGLEIPVITVDEEPVEGAINWDKLLDAADRAGGARERQLVIRQSDLCALPFSSGTTGVSKGVMLTHRNLVANLCSSLFAVTPEMVGQVTVLGLMPFFHIYGITGICCATLRSKGTVVVMGRYDLRTFLAALIKYEVTFAPIVPPIISDMVHKPAVAEFDLARLKLQSVMSAAAPLAPELLRTFEAKFPGVHVQEAYGLTEHSCITLTHGDPDDKSYSRSAKKNSVGFILPNLEVKFIDPETGRSLPKNTPGELCVRSQCVMQGYYNNKEETDRAIDKEGWLHTGDIAYIDDDGDIFIVDRIKEMIKFKGFQVAPAELEAILLTHPSVEDAAVFPMADEEAGEIPAACVVVAHDAKETEEDILSYVASNVAHYKKIRVLQFVDSIPKSPSGKIMRRLLKDAARLKFAKK
>BniUnT019333.1
MGHQANHDDQEFIFRSKLPDIYIPNHLPLHSYCFEHIAQFKDRPCLIDGPTGETYTYAEVELTSRKVAAGLDRLGIKQGDVIMLLLPNCPEFVFAFLGASFLGAISTTANPFYTPAEIAKQAVAAKARLIVTLAAYVEKIRAFAEENSVRVVCVDEAAADDCVRFAELTGADEAEIPPVKISPEDAVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFRSDDVILCVLPLFHIYSLNSILLCGLRVGAGILIMPRYDIARLLELVERYGVTIAPFVPPIVLAIAKSPELERYDLSSIRTVMSGGAPMGKELEDAVKERLPHAKLGQGYGMTEAGPVLSMCLAFAKEPFPIKSGACGTVVRNAEMKIVDPDTGASLPRNQAGEICIRGNQIMKGYINDPKATKETIDEGGWLHTGDIGYIDDDDEIFIVDRLKELIKVRGFQVAPAELEALLVAHPNISDAAVVPMKDENAGEIPVAFVVRSNGSKITEEAIKKYISDQVVYYKRIGRVFFIDKIPKSPSGKILRKDLRAKVATEVAN
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University