Enzyme
The enzyme participates in the flavonoid biosynthesis pathway found in plants. It catalyses the double reduction of anthocyanidins, producing (2R,3R)-flavan-3-ol monomers required for the formation of proanthocyanidins. While the enzyme from the legume Medicago truncatula (MtANR) can use both NADPH and NADH as reductant, that from the crucifer Arabidopsis thaliana (AtANR) uses only NADPH. Also, while the substrate preference of MtANR is cyanidin>pelargonidin>delphinidin, the reverse preference is found with AtANR. cf. EC 1.3.1.112, anthocyanidin reductase [(2S)-flavan-3-ol-forming].
ANR
Enzyme
Anthocyanidin reductase
Enzyme name
EC:1.3.1.77
Entry
Oxidoreductases;Acting on the CH-CH group of donors;With NAD+ or NADP+ as acceptor
Class
(2R,3R)-flavan-3-ol:NAD(P)+ 3,4-oxidoreductase
Sysname
a (2R,3R)-flavan-3-ol + 2 NAD(P)+ = an anthocyanidin with a 3-hydroxy group + 2 NAD(P)H + H+ [RN:R07351 R07352]
Reaction
anthocyanidin with a 3-hydroxy group [CPD:C21381];NADH [CPD:C00004];NADPH [CPD:C00005];H+ [CPD:C00080]
Product

Species information
Boea hygrometrica
Species name
Dorcoceras hygrometricum is a species of eudicot in the family Gesneriaceae (African violet family).
Species info

Gene sequence info
Boea_hygrometrica.ANR.fa
Download
>rna-gnl|WGS:LVEL|mrna.F511_05577
MEKGSCRVCVTGGSGYIASLLVKKLLNEGYTVHATVRKLDDHPKIDILKSFHGADTRLKLFVADIYKPEEFDEAIQGCEFVFHVATPLLHSTGFKHNNRVDATVDSARILASLCIRSGTVRRLIYTASVVAASPLKEDGSGYKELMDETCWTPLDFSNPYSDIILQEYTQSKTLAEKEILRSGDGKIEVVSLVCGLVGGETQMPSPPGSLLAILSLLTNDEPAYNSLKFLEELLARVPILHIEDACNAHIFCMKQDSINGRFLCSNGYVSTAEIAGYYRSKYPELSINKDRFDCLKRDTKWVSTLLCERGFEYKFDWKMVLDDSVRYAKETQMLVGLSS
>rna-gnl|WGS:LVEL|mrna.F511_39373
MEEGKCKVCVTGGSGYIASALIKKLLSEGYIVHTTLRDLNDHPKIDTLKSFYGADTGLKLFKADIYRPEEFEEAILGCEFVFHVATPLLHSDGNKFLLRKQYKNRVDATVDSAKRIASLCVRTGTVRRLLYTASVMAASPLKDDGSGYKEFMDETCWTPANFSIPYTTDFLEEYTKAKTFAERELLSFGDGKLEVVTLACGLVGGETLMPNTPGSVLAILGLLTNDEFGYTALKFLENLLAKVPLAHIEDVINALVFCMKEQTMGGRFLCAKGYVSTADMARYYQNKYPEFSIKREHLECPKRYTKWVSVLLEKRGFEYKYDWRVVLDDSVRCAKKNADVGI
MEKGSCRVCVTGGSGYIASLLVKKLLNEGYTVHATVRKLDDHPKIDILKSFHGADTRLKLFVADIYKPEEFDEAIQGCEFVFHVATPLLHSTGFKHNNRVDATVDSARILASLCIRSGTVRRLIYTASVVAASPLKEDGSGYKELMDETCWTPLDFSNPYSDIILQEYTQSKTLAEKEILRSGDGKIEVVSLVCGLVGGETQMPSPPGSLLAILSLLTNDEPAYNSLKFLEELLARVPILHIEDACNAHIFCMKQDSINGRFLCSNGYVSTAEIAGYYRSKYPELSINKDRFDCLKRDTKWVSTLLCERGFEYKFDWKMVLDDSVRYAKETQMLVGLSS
>rna-gnl|WGS:LVEL|mrna.F511_39373
MEEGKCKVCVTGGSGYIASALIKKLLSEGYIVHTTLRDLNDHPKIDTLKSFYGADTGLKLFKADIYRPEEFEEAILGCEFVFHVATPLLHSDGNKFLLRKQYKNRVDATVDSAKRIASLCVRTGTVRRLLYTASVMAASPLKDDGSGYKEFMDETCWTPANFSIPYTTDFLEEYTKAKTFAERELLSFGDGKLEVVTLACGLVGGETLMPNTPGSVLAILGLLTNDEFGYTALKFLENLLAKVPLAHIEDVINALVFCMKEQTMGGRFLCAKGYVSTADMARYYQNKYPEFSIKREHLECPKRYTKWVSVLLEKRGFEYKYDWRVVLDDSVRCAKKNADVGI

Sheng jun & Dong yang Teams, Yunnan agriculture University