Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Boea hygrometrica
Species name
Dorcoceras hygrometricum is a species of eudicot in the family Gesneriaceae (African violet family).
Species info
Gene sequence info
Boea_hygrometrica.COMT.fa
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>rna-gnl|WGS:LVEL|mrna.F511_09926
MADDQYLEEEFAIQLAFGSVIPMVLRAAIELDIFDIIRKAWPDASLSAFELACQLPTKDPDTAATMLDRILRLLAEHALLNCSTKLLPSGDSERRYSLAPAGKLFSKNEDGVSMAPVSLFVQHKVMMESWYHLKDAILEGTVPFNRAHGKTVFQYAATDPSFNQVCNLAMSSQSVILMTKLAEIYKGFEGLNSLVDVGGGIGSVLHMIVSKYPSVKAINFDLPHVIRDAPSYPGVQHIGGDMFAGVPKGDAIFMKWILHDWNDAENIKILKNCYKALPENGKVIICEYILSETPSNGTSVDAVGALADVVMLAHSPSGKERTLQQYEALAIEAGFTKLFKVCRVYGNSWIMEMHK
>rna-gnl|WGS:LVEL|mrna.F511_05200
MESSDKEEACLFAMQLASASVLPMVLKSAIDLNLLELIKKAGPGSFVSPAQLAAQIPTTNPEAHVMLDRILRLLATYSVVKCRLRTLPDGGVERLYGLEPVCEFLTKNDDGVSMAPLVLMNQDKVLIESWFHLKDAVLDGGIPFNKAYGMTAFEYHGTDPRFNKVFNQGMSNHSTIIMKEILDSYGGFHGLKSIVDVGGGTGAILNMIVSKYPTIKGINFDLPHVVEDAPSYPGVEHVGGDMFVSVPKGDAIFMKWICHDWSDEHCRKILKRCYEALPEKGKVILAECILPDAPDTGLSTKNTVHVDVIMLAHNPGGKERTEKEFEALAKGAGFKGFQKVCCAYNSWIMELHK
>rna-gnl|WGS:LVEL|mrna.F511_01262
MGSTMEVEKEDASLAFAMQLASASIVPYALKVAVELDLLELMKKKGPDAFVSPAEIAAELPSSRPDTHNKLDRILRLLSCYSIVICSVKTMPDGGVERLYSLAPVSKFFTKNEDGVSLGLSLIMSLDRIPTEAKSHLKDSILDGGNPFEKAHKMSGFEYLGTDPRFNKVFNSAMSGNSTIVMKKLVETYEGFKGIQTLVDVGGGIGASLQIILSKHPKIKGINFDLPHVIQNAPSYAGVENIGGDMFVGVPKGDAIFMKWILHDWGDTHCLKILERCREALSNNGKIIVLESILPEIPSEGLICDFQLDVAMLTFNPGGKERTENEFHALAKRAGFKECRMVCRVAPFWVLEFYK
>rna-gnl|WGS:LVEL|mrna.F511_43989
MGPTSRLLRSPRNLKQRNVDRAASVLDSILRVLVSHSFLTCSKTEHGLRYGIAPKGKFFVADERGVSMAPFFALTLQQESANWGISFKDMVLEGRALCENAQRHYANFASNSDANKIFNNAMQCVSTLTMKQILKIYNGFDGMHSLVDVGGGNGATLDMIISKYTSIKGINLDLPTVIQTAPTYKGMNIYMCVFVCVCKEKSTYWPSNHRLYLAGVEHVAGDMFAELPKADAIMLKKGKVIVIEHILPEIPQTDVYSRASSLQNILMLLINGRERTKVEYEAMTKEAGFDELRVVCHAFGAYVMELVKF
>rna-gnl|WGS:LVEL|mrna.F511_44994
MVLEGRALYENAQLHYADFASNPDANKIFNNAMECVSTLTMKQILKIYNGFDGLHSLVDVGGGNGATLDMIISKYTSIKGINLDLPTVIQTAPTYKGVEHVAGDMFAELPKADAIMLKVQYLYIWLITLF
>rna-gnl|WGS:LVEL|mrna.F511_47075
MEKQHYSKHEQEDEAFVECGSACVSHVLRLVLDGSLQLGLFEIIGKSGDGAHLSSFDIASQLETCNVDRAASVLDSILRVLVSHSFLTCSKTEHEIRYGIAPKGKFFVADEGGVSMAPFFALTLQEESANWG
>rna-gnl|WGS:LVEL|mrna.F511_47154
MEKQHYSEHEQEDEAFVKCASACVSHVLRLVLDGSLQLGLFEIIGKSGDGAHLSSFDIASQLETCNVDRAASVLDSILRVLVSHSFLTCSKTEHGLGYGIAPKGKFFVADERGVSMAPFFALTLQQESANWR
MADDQYLEEEFAIQLAFGSVIPMVLRAAIELDIFDIIRKAWPDASLSAFELACQLPTKDPDTAATMLDRILRLLAEHALLNCSTKLLPSGDSERRYSLAPAGKLFSKNEDGVSMAPVSLFVQHKVMMESWYHLKDAILEGTVPFNRAHGKTVFQYAATDPSFNQVCNLAMSSQSVILMTKLAEIYKGFEGLNSLVDVGGGIGSVLHMIVSKYPSVKAINFDLPHVIRDAPSYPGVQHIGGDMFAGVPKGDAIFMKWILHDWNDAENIKILKNCYKALPENGKVIICEYILSETPSNGTSVDAVGALADVVMLAHSPSGKERTLQQYEALAIEAGFTKLFKVCRVYGNSWIMEMHK
>rna-gnl|WGS:LVEL|mrna.F511_05200
MESSDKEEACLFAMQLASASVLPMVLKSAIDLNLLELIKKAGPGSFVSPAQLAAQIPTTNPEAHVMLDRILRLLATYSVVKCRLRTLPDGGVERLYGLEPVCEFLTKNDDGVSMAPLVLMNQDKVLIESWFHLKDAVLDGGIPFNKAYGMTAFEYHGTDPRFNKVFNQGMSNHSTIIMKEILDSYGGFHGLKSIVDVGGGTGAILNMIVSKYPTIKGINFDLPHVVEDAPSYPGVEHVGGDMFVSVPKGDAIFMKWICHDWSDEHCRKILKRCYEALPEKGKVILAECILPDAPDTGLSTKNTVHVDVIMLAHNPGGKERTEKEFEALAKGAGFKGFQKVCCAYNSWIMELHK
>rna-gnl|WGS:LVEL|mrna.F511_01262
MGSTMEVEKEDASLAFAMQLASASIVPYALKVAVELDLLELMKKKGPDAFVSPAEIAAELPSSRPDTHNKLDRILRLLSCYSIVICSVKTMPDGGVERLYSLAPVSKFFTKNEDGVSLGLSLIMSLDRIPTEAKSHLKDSILDGGNPFEKAHKMSGFEYLGTDPRFNKVFNSAMSGNSTIVMKKLVETYEGFKGIQTLVDVGGGIGASLQIILSKHPKIKGINFDLPHVIQNAPSYAGVENIGGDMFVGVPKGDAIFMKWILHDWGDTHCLKILERCREALSNNGKIIVLESILPEIPSEGLICDFQLDVAMLTFNPGGKERTENEFHALAKRAGFKECRMVCRVAPFWVLEFYK
>rna-gnl|WGS:LVEL|mrna.F511_43989
MGPTSRLLRSPRNLKQRNVDRAASVLDSILRVLVSHSFLTCSKTEHGLRYGIAPKGKFFVADERGVSMAPFFALTLQQESANWGISFKDMVLEGRALCENAQRHYANFASNSDANKIFNNAMQCVSTLTMKQILKIYNGFDGMHSLVDVGGGNGATLDMIISKYTSIKGINLDLPTVIQTAPTYKGMNIYMCVFVCVCKEKSTYWPSNHRLYLAGVEHVAGDMFAELPKADAIMLKKGKVIVIEHILPEIPQTDVYSRASSLQNILMLLINGRERTKVEYEAMTKEAGFDELRVVCHAFGAYVMELVKF
>rna-gnl|WGS:LVEL|mrna.F511_44994
MVLEGRALYENAQLHYADFASNPDANKIFNNAMECVSTLTMKQILKIYNGFDGLHSLVDVGGGNGATLDMIISKYTSIKGINLDLPTVIQTAPTYKGVEHVAGDMFAELPKADAIMLKVQYLYIWLITLF
>rna-gnl|WGS:LVEL|mrna.F511_47075
MEKQHYSKHEQEDEAFVECGSACVSHVLRLVLDGSLQLGLFEIIGKSGDGAHLSSFDIASQLETCNVDRAASVLDSILRVLVSHSFLTCSKTEHEIRYGIAPKGKFFVADEGGVSMAPFFALTLQEESANWG
>rna-gnl|WGS:LVEL|mrna.F511_47154
MEKQHYSEHEQEDEAFVKCASACVSHVLRLVLDGSLQLGLFEIIGKSGDGAHLSSFDIASQLETCNVDRAASVLDSILRVLVSHSFLTCSKTEHGLGYGIAPKGKFFVADERGVSMAPFFALTLQQESANWR
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University