Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Boea hygrometrica
Species name
Dorcoceras hygrometricum is a species of eudicot in the family Gesneriaceae (African violet family).
Species info
Gene sequence info
Boea_hygrometrica.HIDH.fa
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>rna-gnl|WGS:LVEL|mrna.F511_29103
MASDSKEIAFDLQAFRIYNDGSIKRFIPIQFIPPSDDPNAAVRSKDVVIDSETGLSVRIFMPGRRCDANQKLPLVVYTHGGAFCIGSATGLTYHNHLTNLVEKAKAIAVSVQYRLAPEHPLPTAFDDSWAAFRWVAAHATSEGPDPWLNEHADFRRVFVGGDSAGGNIANDVAVRAGDSKLPGVEVEGIFLVHPWFGGKEEDKLYKLLCPTSSGRDDDPRLNPAVDPRIGKMAGRRVLFFLAEQDSLRNRGMAYSEGLKKSEWSGEVEIMESLGEGHCFHLFNPNKDTAAALVDRLVAFINGR
>rna-gnl|WGS:LVEL|mrna.F511_09580
MGSLPHIVEDCLGIVRVYSDGSISRLTDINLPMKVQDDGSAVWKDCLFDKEHNLHLRLYKPRSPTDVAQLPQLLPPPLLRSASSPPAAVDDAMSSVEWLRDQTLLSNSGGDGWFANGGVDFARVFIVGDSSGGNLAHHVAVQLRRGSPELAPIRVRGYVLMAPFFGGTVRTKSEEEGPELLLNSEILDRQPKVERFELQDKCYPIKKGPRPPAAVDDAMSSVEWLRDQTLLSNSGGDGWFANGGVDFARVFIVGDSSGGNLAHHVAVQLRRGSPELAPIRVRGYVLMAPFFGGTVRTKSEEEGPELLLNSEILDR
>rna-gnl|WGS:LVEL|mrna.F511_08424
MTALTLDPSLSLQVSSNASKNRAIVDEIDGLIRVYKDGHVERPQIMTHAACSSASEFGVTCRDVIVDKYTNIWARFYVPNASPKLLPLLLYFHGGGFCVGSTSWSCYNEFLAKLASKTGCVIVSVNYRLAPENPLPAAYEDGVKAFVWLRQQSSLGKNEWWTNKCDMSNIFLAGDSAGANIAFNVSLRLARRIDIKGVILIQPFFGGESRTHSEKYMAQPPRSALTLAASDTYWRLSLPRGENRDHPWCNPMAKMAPNLEELRNLSIMVCIAEMDILKDRNLELCAKLGQKVDQIMYKGVGHAFQILNKSTLAKARVHELASHIKNFVHK
>rna-gnl|WGS:LVEL|mrna.F511_14411
MSIVAEAPGFIQVFSDGSVKRFAPETAVASPLTSAGGYKSKDVTVDASKPINARIFRPDDEDINVSGMPVLVYFHGGGFCIGSTTWLGYHIFLGNLAATAKTIIVSVDYRLAPEHRLPTSYEDCYSALEWLGSKADPWLRNADLSRVFLCGDSAGGNIAHHVTIKAIKNKIHGVTVKGLVPIHPFFGSERRTELELAEGSGAEVAMNDMFWRLSLPDGADRDFYGCDFEKAEAEWSLFPALLVFVSGLDFLKERGVMYSDFMKKKGVKEVKLIEAEGEVHVFHAWFPESEATFLLQKQITDFIRIFH
>rna-gnl|WGS:LVEL|mrna.F511_11793
METSATTKAVLHDVPPYLKVYEDGTVERFIGVESVPPTLDSDTGVSSKDVIIIPETGVSARIYRPKPTANHHKKHPLVVYFHGGAFCISSTADPKYHDMLSKLVKEAQVFLVSVDYRLAPESPLPAAYEDSWAALQWVASHLEEHGSEDWLKESADFEKVYLAGDSAGANISHHLAIKAGLPSHNQSRGRFKIAGILLVHPYFWGKDPIGVEKENPFFKSVVDKWWEFVCPSDLGCDDPLINPFVIGAPSVEGLASGKILVCVAGNDILRERGRLYYDSLVKSAWKGQAWFLQTEGEDHVFHVIDSGSEKAMELIKKCAQFFNKD
>rna-gnl|WGS:LVEL|mrna.F511_19370
MAANNADSPTPPSPHEVDECRGVLRVYSDGSIWRSNKPSFDVPVRDNGSILWKDVPFGSTNSLQLRLYKPASPLAAKLPVFYYIHGGGFCIGSRTWPNCQNYCFKLALELQAVVISPDYRLAPENRLPAAIEDGYAAVKWLQQQATAEEPDKWLTDVADFSRVFISGDSAGGNIAHHLAVQLRAGSPELSPIRVRGYVYLAPFFGGTARTKFEAEGPKGATLNLELIDRFWRLSIPVGETTDHPLVNPFGPVSPNLEEIELDPILVVVGGSDLLKDRAKEYADKLKRWGKGLGTRSLKGNSMGSSLLIQIPNLPNN
>rna-gnl|WGS:LVEL|mrna.F511_10295
MSGKNSSVFFLLSTYTLHLLLTTSFAANSDNEILYDIYPFIRVYRNGTIQRFIGQGFLPASTDPRTGVQSKDVSIAKDLNVSARIYLPKNAHPGHKIPLLIYYHGGGFFTESAFSPTYHNHMNSLVAKANIVAVSVNYRLAPEHPLPIAYQDSWLALKWVFHHSSGKGGQPWLTKYADFRRVYLGGDSAGGNIAHNMAIRVGLLVSDPDIKVKGMFLNCPGFWGKRRVGNESADSNRVKLSEAIWLHAYPNITGLDDPLVNPGMDPGLKTLGCRRVLVYVGGNDGLRFRGWYYMQVLKRSGWDGIVKVVEVKGEGHVFNLNNPTTPKAIAMLKALASFINQ
>rna-gnl|WGS:LVEL|mrna.F511_10293
MAAANSDEILHDLSPLLRHYKDGRVERMLGSAFIQPSFDPETGVQSKDVEISAGINLSARLYLPKNASPAEKLPILLYFHGGGFVIESAFSELYQNHLNHLVAEANVVAVSVNYRLAPEHPVPAAFEDSWLALEWIATQFREEGREEWIKQHADANRVFLGGDSAGGTIAHYVALRAGIDKLKGGITLRGAFLNCPYFWGELPIADEMNHPHYSKSFLDTLWKYASPSSSQGSDDPLINPEKDPRIARLGCKRLLVHVAEKDVLRARGLLYKDILKKNGWDGEIEVVDVEGEVHVFSVFTPTSETGVAMIKKVASFINAE
>rna-gnl|WGS:LVEL|mrna.F511_10294
MFSGKNSTPLLLFTYTLHLLLTTSFAANAANDILYDIYPFIRVYRNGTIQRFIGQGFLPASTDPRTGVQSKDVSIAKDLNVSARIYLPKNALPGHKIPLLIYYHGGGFFTESAFSPTYHYHMNSLVAKANIVAVSVNYRLAPEHPLPIAYQDSWLALKWVFHHASGKGGEPWLTNYADFGRVYLGGDSAGGNIAHNMAVRVGLEESDPGVKVNGMFLNCPYFWGKRLVGNESADAHVRNFLEAIWLHAYPNSPGLDDPLVNPGKDPGLKTLGCKRVLVYVAGNDGLRFRGWYYMQVLKESGWDGIVKVVEVKGEDHVFNLINPTTPKAIAMLQVLASFLNQ
>rna-gnl|WGS:LVEL|mrna.F511_01571
MDPQSDQATHDFPPFFRVHTSGLIERYIEHDFLPPSEHPSSGVLSKDVVVSPRNNVTARIYLPRTEAPHRNLPLVIYVHGGGFSVESAFSSLYHNYVNSLAAESKSVVVSVEYRLAPEHPIPACYEDCWAATKWVESHSGAGKGDDPWITDYVDFKRVFVAGDSAGANIAHEMVVRAGAESELGIQFTGLILIHPFFGIGKVPKLWDFISPETTGPTDPMLNPAAHRRLLSNLRCERVLVCVAEKDFLKESGVKYRQALKDSDWKGLLEFFETYGEGHVFHLLQPDSENAPLLMNRVIEFIHSEFVLSLL
>rna-gnl|WGS:LVEL|mrna.F511_01570
MKHDFLPASKHPKTGVLSKDVVVSPQNGVTARIYVPPTPGKKLPLIIYVHGGGFAIESAFSSQYHNYANHLAAESGAVVVSVEYRLAPEHPLPACYDDCWDATKWVESHSREWDEGDPWITDYVDFTRVFAAGDSAGANIAHEIVVRAGEEPELGIKFVGLILIHPYFGMGNAEHMWNVICPGTSGPDDSRLHPAAHKKLLSNLRCKRVLVCVAGKDSLKERGVKYHEALKKSDWNGVVEFIETEGEGHVFHLQQPDSDKASLLMKRVVEFINK
MASDSKEIAFDLQAFRIYNDGSIKRFIPIQFIPPSDDPNAAVRSKDVVIDSETGLSVRIFMPGRRCDANQKLPLVVYTHGGAFCIGSATGLTYHNHLTNLVEKAKAIAVSVQYRLAPEHPLPTAFDDSWAAFRWVAAHATSEGPDPWLNEHADFRRVFVGGDSAGGNIANDVAVRAGDSKLPGVEVEGIFLVHPWFGGKEEDKLYKLLCPTSSGRDDDPRLNPAVDPRIGKMAGRRVLFFLAEQDSLRNRGMAYSEGLKKSEWSGEVEIMESLGEGHCFHLFNPNKDTAAALVDRLVAFINGR
>rna-gnl|WGS:LVEL|mrna.F511_09580
MGSLPHIVEDCLGIVRVYSDGSISRLTDINLPMKVQDDGSAVWKDCLFDKEHNLHLRLYKPRSPTDVAQLPQLLPPPLLRSASSPPAAVDDAMSSVEWLRDQTLLSNSGGDGWFANGGVDFARVFIVGDSSGGNLAHHVAVQLRRGSPELAPIRVRGYVLMAPFFGGTVRTKSEEEGPELLLNSEILDRQPKVERFELQDKCYPIKKGPRPPAAVDDAMSSVEWLRDQTLLSNSGGDGWFANGGVDFARVFIVGDSSGGNLAHHVAVQLRRGSPELAPIRVRGYVLMAPFFGGTVRTKSEEEGPELLLNSEILDR
>rna-gnl|WGS:LVEL|mrna.F511_08424
MTALTLDPSLSLQVSSNASKNRAIVDEIDGLIRVYKDGHVERPQIMTHAACSSASEFGVTCRDVIVDKYTNIWARFYVPNASPKLLPLLLYFHGGGFCVGSTSWSCYNEFLAKLASKTGCVIVSVNYRLAPENPLPAAYEDGVKAFVWLRQQSSLGKNEWWTNKCDMSNIFLAGDSAGANIAFNVSLRLARRIDIKGVILIQPFFGGESRTHSEKYMAQPPRSALTLAASDTYWRLSLPRGENRDHPWCNPMAKMAPNLEELRNLSIMVCIAEMDILKDRNLELCAKLGQKVDQIMYKGVGHAFQILNKSTLAKARVHELASHIKNFVHK
>rna-gnl|WGS:LVEL|mrna.F511_14411
MSIVAEAPGFIQVFSDGSVKRFAPETAVASPLTSAGGYKSKDVTVDASKPINARIFRPDDEDINVSGMPVLVYFHGGGFCIGSTTWLGYHIFLGNLAATAKTIIVSVDYRLAPEHRLPTSYEDCYSALEWLGSKADPWLRNADLSRVFLCGDSAGGNIAHHVTIKAIKNKIHGVTVKGLVPIHPFFGSERRTELELAEGSGAEVAMNDMFWRLSLPDGADRDFYGCDFEKAEAEWSLFPALLVFVSGLDFLKERGVMYSDFMKKKGVKEVKLIEAEGEVHVFHAWFPESEATFLLQKQITDFIRIFH
>rna-gnl|WGS:LVEL|mrna.F511_11793
METSATTKAVLHDVPPYLKVYEDGTVERFIGVESVPPTLDSDTGVSSKDVIIIPETGVSARIYRPKPTANHHKKHPLVVYFHGGAFCISSTADPKYHDMLSKLVKEAQVFLVSVDYRLAPESPLPAAYEDSWAALQWVASHLEEHGSEDWLKESADFEKVYLAGDSAGANISHHLAIKAGLPSHNQSRGRFKIAGILLVHPYFWGKDPIGVEKENPFFKSVVDKWWEFVCPSDLGCDDPLINPFVIGAPSVEGLASGKILVCVAGNDILRERGRLYYDSLVKSAWKGQAWFLQTEGEDHVFHVIDSGSEKAMELIKKCAQFFNKD
>rna-gnl|WGS:LVEL|mrna.F511_19370
MAANNADSPTPPSPHEVDECRGVLRVYSDGSIWRSNKPSFDVPVRDNGSILWKDVPFGSTNSLQLRLYKPASPLAAKLPVFYYIHGGGFCIGSRTWPNCQNYCFKLALELQAVVISPDYRLAPENRLPAAIEDGYAAVKWLQQQATAEEPDKWLTDVADFSRVFISGDSAGGNIAHHLAVQLRAGSPELSPIRVRGYVYLAPFFGGTARTKFEAEGPKGATLNLELIDRFWRLSIPVGETTDHPLVNPFGPVSPNLEEIELDPILVVVGGSDLLKDRAKEYADKLKRWGKGLGTRSLKGNSMGSSLLIQIPNLPNN
>rna-gnl|WGS:LVEL|mrna.F511_10295
MSGKNSSVFFLLSTYTLHLLLTTSFAANSDNEILYDIYPFIRVYRNGTIQRFIGQGFLPASTDPRTGVQSKDVSIAKDLNVSARIYLPKNAHPGHKIPLLIYYHGGGFFTESAFSPTYHNHMNSLVAKANIVAVSVNYRLAPEHPLPIAYQDSWLALKWVFHHSSGKGGQPWLTKYADFRRVYLGGDSAGGNIAHNMAIRVGLLVSDPDIKVKGMFLNCPGFWGKRRVGNESADSNRVKLSEAIWLHAYPNITGLDDPLVNPGMDPGLKTLGCRRVLVYVGGNDGLRFRGWYYMQVLKRSGWDGIVKVVEVKGEGHVFNLNNPTTPKAIAMLKALASFINQ
>rna-gnl|WGS:LVEL|mrna.F511_10293
MAAANSDEILHDLSPLLRHYKDGRVERMLGSAFIQPSFDPETGVQSKDVEISAGINLSARLYLPKNASPAEKLPILLYFHGGGFVIESAFSELYQNHLNHLVAEANVVAVSVNYRLAPEHPVPAAFEDSWLALEWIATQFREEGREEWIKQHADANRVFLGGDSAGGTIAHYVALRAGIDKLKGGITLRGAFLNCPYFWGELPIADEMNHPHYSKSFLDTLWKYASPSSSQGSDDPLINPEKDPRIARLGCKRLLVHVAEKDVLRARGLLYKDILKKNGWDGEIEVVDVEGEVHVFSVFTPTSETGVAMIKKVASFINAE
>rna-gnl|WGS:LVEL|mrna.F511_10294
MFSGKNSTPLLLFTYTLHLLLTTSFAANAANDILYDIYPFIRVYRNGTIQRFIGQGFLPASTDPRTGVQSKDVSIAKDLNVSARIYLPKNALPGHKIPLLIYYHGGGFFTESAFSPTYHYHMNSLVAKANIVAVSVNYRLAPEHPLPIAYQDSWLALKWVFHHASGKGGEPWLTNYADFGRVYLGGDSAGGNIAHNMAVRVGLEESDPGVKVNGMFLNCPYFWGKRLVGNESADAHVRNFLEAIWLHAYPNSPGLDDPLVNPGKDPGLKTLGCKRVLVYVAGNDGLRFRGWYYMQVLKESGWDGIVKVVEVKGEDHVFNLINPTTPKAIAMLQVLASFLNQ
>rna-gnl|WGS:LVEL|mrna.F511_01571
MDPQSDQATHDFPPFFRVHTSGLIERYIEHDFLPPSEHPSSGVLSKDVVVSPRNNVTARIYLPRTEAPHRNLPLVIYVHGGGFSVESAFSSLYHNYVNSLAAESKSVVVSVEYRLAPEHPIPACYEDCWAATKWVESHSGAGKGDDPWITDYVDFKRVFVAGDSAGANIAHEMVVRAGAESELGIQFTGLILIHPFFGIGKVPKLWDFISPETTGPTDPMLNPAAHRRLLSNLRCERVLVCVAEKDFLKESGVKYRQALKDSDWKGLLEFFETYGEGHVFHLLQPDSENAPLLMNRVIEFIHSEFVLSLL
>rna-gnl|WGS:LVEL|mrna.F511_01570
MKHDFLPASKHPKTGVLSKDVVVSPQNGVTARIYVPPTPGKKLPLIIYVHGGGFAIESAFSSQYHNYANHLAAESGAVVVSVEYRLAPEHPLPACYDDCWDATKWVESHSREWDEGDPWITDYVDFTRVFAAGDSAGANIAHEIVVRAGEEPELGIKFVGLILIHPYFGMGNAEHMWNVICPGTSGPDDSRLHPAAHKKLLSNLRCKRVLVCVAGKDSLKERGVKYHEALKKSDWNGVVEFIETEGEGHVFHLQQPDSDKASLLMKRVVEFINK
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University