Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Boea hygrometrica
Species name
Dorcoceras hygrometricum is a species of eudicot in the family Gesneriaceae (African violet family).
Species info
Gene sequence info
Boea_hygrometrica.4CL.fa
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>rna-gnl|WGS:LVEL|mrna.F511_12530
MDPISKKEDIIFRSKLPDIYIPKHLPLHSYCFENISKHSKRPCLINGPTGEVYTYEEVELASRKVASGLSKLGVQQGDSIMLLLPNSPEYVLAFLGSSHIGAITTMANPYFTPAEVVKQAKASRAKIIVTQACHVAKVEGYALDNGVKVMCIDAPPAEWCLSFSELTSADEKDIPAVKIHPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYGSQRRCDAKFEIVSVLELIQKYKVTIGPFVPPIVLAIAKSPVVDKYELSSVRMVLSGAAPLGKELEEAARVKFPNAIVGQGYGMTEAGPVLSMCLAFAKQPFEIKSGACGTVVINAEMKIVDTETGASLGRNQPGEICIRGDQIMKGYLNDPVATENTIDKEGWLHTGDIGFIDNDDEIFIVDRLKELIKYKGFQVAPAELEALLLNHPSVSAAAVVSMQDEQAGEVPVAFVVRSNGSIVSEDKIKKYISDQVVFYKRLSRVFFIDSIPVSPSGKILRKELRARLAAGFT
>rna-gnl|WGS:LVEL|mrna.F511_16152
MSTPVIYGKDGIYRSPRPPISLPKDPRMSMIPFLFRDITAISKIPALVDAETGHALTFSDLRTQVFKLSQALLSLNISKNDVVLILSPNSILFPLCFFAIVSIGAIAATANPQYTINELTKQVLDSNPKLIITIHELYDKIKNFGLPCVMISPKTSSFVDRTTNDPIWYYQEMMKSDDTSKVRTRPSVLQTDAAAILYSSGTTGTSKGVVLTHRNFIASALMTTSDQETSNDPKNVVLCFLPMFHVFGLSTILYAQLQRGNTVVIMAHYEIGKVLMAIERYKVTLLYVVPPVIVTFVKQNEIVKLYDISCLREIATGAAPLGKDVMEECGKVFPQAALYQGYGMTETCGVISVERQKATTSRHSGSTGVLNPGVEAQIIDIQTMKPLPPFKTGEIRIRGLNVMQGYFKKEKATIETIDDHGWLHTGDLGYFDEEGQLFVVDRIKELIKCKGFQVAPAELEELLLSHPKIKDAAVIGLPDAEAGEVPIAYIVPLFINSLAEEDVKKLIAQQAVLSWSENAKRLN
>rna-gnl|WGS:LVEL|mrna.F511_22538
MGTITKQEEIIFRSKLPDIYIPKHLPLHSYCFENISKFSSRPCLIDGSTDEVYTYKDVELTSRKVGSGLSKLGINQGDTIMLLLPNSPHFVFAFLGASYIGAVSTMANPFFTPAEVLKQVKASNAKLIITQACYVDKVRDFAQENGITVVCIDSTPPEGCHHFSELTSADERDIPAVKIHPEDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYIHMEDVMLCVMPLFHIYSLNSVLLCGLRVGASILIMKKFDIVPFLELIQKYKVTIGPFVPPIVLAIAKSPVVDKYDLSSVRTVMSGAAPLGRELEDAVRIKFPSAKLGQGYGMTEAGPVLAMCLAFAKEPLEIKSGACGTVVRNAEMKIVDTETGISLGRNQAGEICIRGDQIMKGYLNDPESTEKTIDKEGWLHTGDIGFIDADDELFIVDRLKEIIKYKGFQVAPAELEAILLNHPSISDAAVVPMKDEAAGEVPVAFVVRSNGSAISEDEIKQFVSKQVIFYKRINRVFFIDAVPKSPSGKILRKDLRARLAAGV
>rna-gnl|WGS:LVEL|mrna.F511_14479
MASVKTQNPELPSDLVSTQKQSTSDQTDHIFVSKLPPITIPNNIPLHSFCFQNLSQKSDRTCLLVGNTGRRYTYAEVYQTCRRTAAGLSNLGVKKGDVIMLLLQNCAEFAFCFMGASMIGAVTTTANPFLTRAEIFKQFNASKSKLIVTQGQYVDKLRDPVDAGSNFLKLGRDFSVITVDEPPEGCLPFSVLSEADENDAPEVEIDPDDAVALPFSSGTTGLPKGVILTHKSLITSVAQQVDGENPNWHVKEDDVVLCVLPLFHIFALNAALLCSLRVGAGILLVQKFEMGLLLELIQSHRVSVAAVVPPLVLALAKNPVVDKYDLTSIRLVQSGAAPLGTELEEALLRRLPQAVFGQGYGMTEAGPVLCLSPLFAKQPFPTKSGSCGNVVRNAELKVVSPETGHSLPRNQPGELCIRGSQIMKGYLNDPEATARTIDVDGWLHTGDIGYIDEDDDVFIIDRLKELIKFKGFQVPPAELESLLLSHPNIADAAVVPQNDEAAGEVPVAFVVASSGSEISGEEVKEFVAKQVVFYKRLHKVHFVNAIPKSPAGKILRRELRAKLNAL
>rna-gnl|WGS:LVEL|mrna.F511_07463
METDPKNLAEDEFIFRSKCLPVSVPDDMTLPEFVLSDVDLYLDKMAFVDAVTGKGYTYGEVSRDIKRFSKALRSLGLRKGRVVVVLLPNVAEYAIIALGIMAAGGVFSGANPSAHASEIQKQVEAADAKLIVTDGSTYHKVKDLGLPIIIQGEDRVDGTIYWDELLEAADKASTDTIDEKVEQTDLCALPFSSGTTGLSKGVMLTHRNLVANLCSSLHSVGPDLIGQITILGLIPFFHIYGLTGICCATIRNKGKVVLMRRYDLRTFLNALITHEVTFAPIVPPIILGLVKNPTVDEFDLSKLKLRSIMTAAAPLAPEVLKEFENKFPGVEVQEAYGMTEHSCITLTHGDPNKGRGISKRNSVGFILPNLEVKFIDPETGHSLPKNTPGEICVRSQCVMKGYYKNEYETTLTIDKDGWLHTGDIGYIDDDGDVFLVDRIKELIKYKGFQVAPAELEAILLTHPSVEDAAVVGLPDQESGEIPAAAVVLNSKARESEEDIMNYVSSNVASYKRVRVLQFVDAIPKSPSGKIMRRIIKETMINNI
>rna-gnl|WGS:LVEL|mrna.F511_14470
MEKSGYGRDGIYRSLRPPLFLPNDPNLSMISFLFRNASSFADKPALIDSHTGKILTFSHFKSMVSKVSHGLLELGIKKNDVVLIFSPNTIQFPLSFFGVVTIGAIATTVNPLYTVSELSKQVKDSKPKLIITVQDLLPKVKDIDLPVILLEDEKIGKEQVFNFPNKVTLFTQLVNNEGSIELDGTVNGVRQNDTAALLYSSGTTGTSKGVILTHRNFICASLMITADQESAGDLHNVYLCVLPMFHVFGLAVIMYSQLQRGSAIVSMSKFDLEMILRSVEKYGVTHLWVVPPIVLVLAKNSAVKKYNLSSLKQIGSGAAPLGRELMQECAKNFPQAVVCQGYGMTETCGIVSIENAYAGPRHSGSAGMLVSGVESLIVSVDKLRPLPPGQLGEIWVRGPNMMQGYVNNPQATKLTIDKHGWVHTGDLGYFDDNGQLFVVDRIKELIKYKGFQVAPAELEGLLISHPEILDAVVIPFPDTEAGEVPIAYVVRSPVAPFKRLKRVTFINTVPKSASGKILRRELIEKVRAKL
>rna-gnl|WGS:LVEL|mrna.F511_02506
MECREEKRDHIFRSKLDDIYIPNHLPIHAYCFQNLSSHLSRPAIINGATGEVFTHHELELTARRLAVGFHRIGIRQGHVIMLLLHNSPEFVFAFLAASYIGATTTTANPLYSAAEIDFQAKISKPKLIVTHACHLHKVEDYALNNGAVIVCVDSPPLPHLHLSELKKSDETLMPEVKIHSDDTAVLPFSSGTTGLPKAVMLSHKNIVTCVSVQVDGENPTLHVHAGDLTLCVLPLFHVYSMITIMLCSLRVGSGILIMQKYEINELMGLIQKYKVSIAPFVPPILLAMAKSPEAGAKFDLSSVRRVMCGAAAMDRKLQESVREKLPNATLGQGYGMTEAGVLSMCLGFAKKPFKFKYGSCGSVIRNARMKIVDPLTRASLGRNQPGEICITGDQVMLGYYNDPEATKKTIDEEGWLHTGDIGYIDEDDELFIVDRLKELIKCKGFHVAPAEIEALLLAHPAISDAAVVARKDEVTGEVPVAFVVRAKGSEISDQEIKHYVSKQVVSYKRIRGVYFVNEIPKAPSGKTLRRLLRSRL
>rna-gnl|WGS:LVEL|mrna.F511_28422
MNYENYDPCFPDQPVVDLYLRTWANLPAFRLKDAFVWVDDSPARMGASPSMTYGELNSSVQCISSSLLQQLRRGDTVVILCEPGLELVEVIFACQRAGLKAVPTTPPHPSFASANHHHLARVLSQTKPKAAIAAKCYINRVKEYVSSNYSSSSNRFSQLLQMVEWIPLEDIKGKAHRKASNEQWDFARYSGCRADDVYLIQYTSGATGIPKPVLVTAGAAANNVRTARKAYDLHPNSVIVSWLPQLWLELISEYNATCTPVPSFTLPLVLKRGGVGEGSSRISLESLKNLIIINEPIYKALVDEFVDAVGQFGLKPSCISPSYGLAENCTFVSTAWRSGNDEMFPVYRSLLPSARLSSSVEEAEEIQIVVVNQETHELVNDGIEGEIWLSSPSNASGYLDHPSLTREVFNGRLKNINTAGCFVRTGDRGIVKGKERYLFVTGRCADIIKLENGQEIHPHYIETAAYNSCRNLIRGGCAAAFEVARQIVLVAEVQISEGESLFFKKISETIRKEVKNKENVELGLVVLAKCGSLPKTTSGKIQRWAAKNKLVEGGFKVVTKMEFGNNGDSSLLFKRMIRENEGIKEKDNMVEGQEEIMLATKPYRNHVSLLSSM
MDPISKKEDIIFRSKLPDIYIPKHLPLHSYCFENISKHSKRPCLINGPTGEVYTYEEVELASRKVASGLSKLGVQQGDSIMLLLPNSPEYVLAFLGSSHIGAITTMANPYFTPAEVVKQAKASRAKIIVTQACHVAKVEGYALDNGVKVMCIDAPPAEWCLSFSELTSADEKDIPAVKIHPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYGSQRRCDAKFEIVSVLELIQKYKVTIGPFVPPIVLAIAKSPVVDKYELSSVRMVLSGAAPLGKELEEAARVKFPNAIVGQGYGMTEAGPVLSMCLAFAKQPFEIKSGACGTVVINAEMKIVDTETGASLGRNQPGEICIRGDQIMKGYLNDPVATENTIDKEGWLHTGDIGFIDNDDEIFIVDRLKELIKYKGFQVAPAELEALLLNHPSVSAAAVVSMQDEQAGEVPVAFVVRSNGSIVSEDKIKKYISDQVVFYKRLSRVFFIDSIPVSPSGKILRKELRARLAAGFT
>rna-gnl|WGS:LVEL|mrna.F511_16152
MSTPVIYGKDGIYRSPRPPISLPKDPRMSMIPFLFRDITAISKIPALVDAETGHALTFSDLRTQVFKLSQALLSLNISKNDVVLILSPNSILFPLCFFAIVSIGAIAATANPQYTINELTKQVLDSNPKLIITIHELYDKIKNFGLPCVMISPKTSSFVDRTTNDPIWYYQEMMKSDDTSKVRTRPSVLQTDAAAILYSSGTTGTSKGVVLTHRNFIASALMTTSDQETSNDPKNVVLCFLPMFHVFGLSTILYAQLQRGNTVVIMAHYEIGKVLMAIERYKVTLLYVVPPVIVTFVKQNEIVKLYDISCLREIATGAAPLGKDVMEECGKVFPQAALYQGYGMTETCGVISVERQKATTSRHSGSTGVLNPGVEAQIIDIQTMKPLPPFKTGEIRIRGLNVMQGYFKKEKATIETIDDHGWLHTGDLGYFDEEGQLFVVDRIKELIKCKGFQVAPAELEELLLSHPKIKDAAVIGLPDAEAGEVPIAYIVPLFINSLAEEDVKKLIAQQAVLSWSENAKRLN
>rna-gnl|WGS:LVEL|mrna.F511_22538
MGTITKQEEIIFRSKLPDIYIPKHLPLHSYCFENISKFSSRPCLIDGSTDEVYTYKDVELTSRKVGSGLSKLGINQGDTIMLLLPNSPHFVFAFLGASYIGAVSTMANPFFTPAEVLKQVKASNAKLIITQACYVDKVRDFAQENGITVVCIDSTPPEGCHHFSELTSADERDIPAVKIHPEDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYIHMEDVMLCVMPLFHIYSLNSVLLCGLRVGASILIMKKFDIVPFLELIQKYKVTIGPFVPPIVLAIAKSPVVDKYDLSSVRTVMSGAAPLGRELEDAVRIKFPSAKLGQGYGMTEAGPVLAMCLAFAKEPLEIKSGACGTVVRNAEMKIVDTETGISLGRNQAGEICIRGDQIMKGYLNDPESTEKTIDKEGWLHTGDIGFIDADDELFIVDRLKEIIKYKGFQVAPAELEAILLNHPSISDAAVVPMKDEAAGEVPVAFVVRSNGSAISEDEIKQFVSKQVIFYKRINRVFFIDAVPKSPSGKILRKDLRARLAAGV
>rna-gnl|WGS:LVEL|mrna.F511_14479
MASVKTQNPELPSDLVSTQKQSTSDQTDHIFVSKLPPITIPNNIPLHSFCFQNLSQKSDRTCLLVGNTGRRYTYAEVYQTCRRTAAGLSNLGVKKGDVIMLLLQNCAEFAFCFMGASMIGAVTTTANPFLTRAEIFKQFNASKSKLIVTQGQYVDKLRDPVDAGSNFLKLGRDFSVITVDEPPEGCLPFSVLSEADENDAPEVEIDPDDAVALPFSSGTTGLPKGVILTHKSLITSVAQQVDGENPNWHVKEDDVVLCVLPLFHIFALNAALLCSLRVGAGILLVQKFEMGLLLELIQSHRVSVAAVVPPLVLALAKNPVVDKYDLTSIRLVQSGAAPLGTELEEALLRRLPQAVFGQGYGMTEAGPVLCLSPLFAKQPFPTKSGSCGNVVRNAELKVVSPETGHSLPRNQPGELCIRGSQIMKGYLNDPEATARTIDVDGWLHTGDIGYIDEDDDVFIIDRLKELIKFKGFQVPPAELESLLLSHPNIADAAVVPQNDEAAGEVPVAFVVASSGSEISGEEVKEFVAKQVVFYKRLHKVHFVNAIPKSPAGKILRRELRAKLNAL
>rna-gnl|WGS:LVEL|mrna.F511_07463
METDPKNLAEDEFIFRSKCLPVSVPDDMTLPEFVLSDVDLYLDKMAFVDAVTGKGYTYGEVSRDIKRFSKALRSLGLRKGRVVVVLLPNVAEYAIIALGIMAAGGVFSGANPSAHASEIQKQVEAADAKLIVTDGSTYHKVKDLGLPIIIQGEDRVDGTIYWDELLEAADKASTDTIDEKVEQTDLCALPFSSGTTGLSKGVMLTHRNLVANLCSSLHSVGPDLIGQITILGLIPFFHIYGLTGICCATIRNKGKVVLMRRYDLRTFLNALITHEVTFAPIVPPIILGLVKNPTVDEFDLSKLKLRSIMTAAAPLAPEVLKEFENKFPGVEVQEAYGMTEHSCITLTHGDPNKGRGISKRNSVGFILPNLEVKFIDPETGHSLPKNTPGEICVRSQCVMKGYYKNEYETTLTIDKDGWLHTGDIGYIDDDGDVFLVDRIKELIKYKGFQVAPAELEAILLTHPSVEDAAVVGLPDQESGEIPAAAVVLNSKARESEEDIMNYVSSNVASYKRVRVLQFVDAIPKSPSGKIMRRIIKETMINNI
>rna-gnl|WGS:LVEL|mrna.F511_14470
MEKSGYGRDGIYRSLRPPLFLPNDPNLSMISFLFRNASSFADKPALIDSHTGKILTFSHFKSMVSKVSHGLLELGIKKNDVVLIFSPNTIQFPLSFFGVVTIGAIATTVNPLYTVSELSKQVKDSKPKLIITVQDLLPKVKDIDLPVILLEDEKIGKEQVFNFPNKVTLFTQLVNNEGSIELDGTVNGVRQNDTAALLYSSGTTGTSKGVILTHRNFICASLMITADQESAGDLHNVYLCVLPMFHVFGLAVIMYSQLQRGSAIVSMSKFDLEMILRSVEKYGVTHLWVVPPIVLVLAKNSAVKKYNLSSLKQIGSGAAPLGRELMQECAKNFPQAVVCQGYGMTETCGIVSIENAYAGPRHSGSAGMLVSGVESLIVSVDKLRPLPPGQLGEIWVRGPNMMQGYVNNPQATKLTIDKHGWVHTGDLGYFDDNGQLFVVDRIKELIKYKGFQVAPAELEGLLISHPEILDAVVIPFPDTEAGEVPIAYVVRSPVAPFKRLKRVTFINTVPKSASGKILRRELIEKVRAKL
>rna-gnl|WGS:LVEL|mrna.F511_02506
MECREEKRDHIFRSKLDDIYIPNHLPIHAYCFQNLSSHLSRPAIINGATGEVFTHHELELTARRLAVGFHRIGIRQGHVIMLLLHNSPEFVFAFLAASYIGATTTTANPLYSAAEIDFQAKISKPKLIVTHACHLHKVEDYALNNGAVIVCVDSPPLPHLHLSELKKSDETLMPEVKIHSDDTAVLPFSSGTTGLPKAVMLSHKNIVTCVSVQVDGENPTLHVHAGDLTLCVLPLFHVYSMITIMLCSLRVGSGILIMQKYEINELMGLIQKYKVSIAPFVPPILLAMAKSPEAGAKFDLSSVRRVMCGAAAMDRKLQESVREKLPNATLGQGYGMTEAGVLSMCLGFAKKPFKFKYGSCGSVIRNARMKIVDPLTRASLGRNQPGEICITGDQVMLGYYNDPEATKKTIDEEGWLHTGDIGYIDEDDELFIVDRLKELIKCKGFHVAPAEIEALLLAHPAISDAAVVARKDEVTGEVPVAFVVRAKGSEISDQEIKHYVSKQVVSYKRIRGVYFVNEIPKAPSGKTLRRLLRSRL
>rna-gnl|WGS:LVEL|mrna.F511_28422
MNYENYDPCFPDQPVVDLYLRTWANLPAFRLKDAFVWVDDSPARMGASPSMTYGELNSSVQCISSSLLQQLRRGDTVVILCEPGLELVEVIFACQRAGLKAVPTTPPHPSFASANHHHLARVLSQTKPKAAIAAKCYINRVKEYVSSNYSSSSNRFSQLLQMVEWIPLEDIKGKAHRKASNEQWDFARYSGCRADDVYLIQYTSGATGIPKPVLVTAGAAANNVRTARKAYDLHPNSVIVSWLPQLWLELISEYNATCTPVPSFTLPLVLKRGGVGEGSSRISLESLKNLIIINEPIYKALVDEFVDAVGQFGLKPSCISPSYGLAENCTFVSTAWRSGNDEMFPVYRSLLPSARLSSSVEEAEEIQIVVVNQETHELVNDGIEGEIWLSSPSNASGYLDHPSLTREVFNGRLKNINTAGCFVRTGDRGIVKGKERYLFVTGRCADIIKLENGQEIHPHYIETAAYNSCRNLIRGGCAAAFEVARQIVLVAEVQISEGESLFFKKISETIRKEVKNKENVELGLVVLAKCGSLPKTTSGKIQRWAAKNKLVEGGFKVVTKMEFGNNGDSSLLFKRMIRENEGIKEKDNMVEGQEEIMLATKPYRNHVSLLSSM
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University