Enzyme
The enzyme participates in the flavonoid biosynthesis pathway found in plants. It catalyses the double reduction of anthocyanidins, producing (2R,3R)-flavan-3-ol monomers required for the formation of proanthocyanidins. While the enzyme from the legume Medicago truncatula (MtANR) can use both NADPH and NADH as reductant, that from the crucifer Arabidopsis thaliana (AtANR) uses only NADPH. Also, while the substrate preference of MtANR is cyanidin>pelargonidin>delphinidin, the reverse preference is found with AtANR. cf. EC 1.3.1.112, anthocyanidin reductase [(2S)-flavan-3-ol-forming].
ANR
Enzyme
Anthocyanidin reductase
Enzyme name
EC:1.3.1.77
Entry
Oxidoreductases;Acting on the CH-CH group of donors;With NAD+ or NADP+ as acceptor
Class
(2R,3R)-flavan-3-ol:NAD(P)+ 3,4-oxidoreductase
Sysname
a (2R,3R)-flavan-3-ol + 2 NAD(P)+ = an anthocyanidin with a 3-hydroxy group + 2 NAD(P)H + H+ [RN:R07351 R07352]
Reaction
anthocyanidin with a 3-hydroxy group [CPD:C21381];NADH [CPD:C00004];NADPH [CPD:C00005];H+ [CPD:C00080]
Product
Species information
Betula platyphylla
Species name
Asian white birch (Betula platyphylla) is a species of eudicot in the family Betulaceae (birch family).
Species info
Gene sequence info
Betula_platyphylla.ANR.fa
Download
>BPChr02G14599.v1.1.679
MDLDRMWNYSFCKLIGLRFKIDDDWYSVGNINSDTFDDLQVHFSHLLEGTIFDQLDKGVLVLENGWDEIAQEFIEHGSCETTYVGYELINEAIDIDLWWGFRVADDIGKARQGFANVVDHIVKKQIKMGEKSYCRVCVTGASGYIGSWLVKKLLEKGYTVHATLRNLGETSKVDLLKSLPNADNRLVLFQADIYNPTDFEPAIRGCEYVFHVATPMQHYTQSSQYKDTAEAAIAGVRSIADSCIRSQTVKRLIYTASMTASSPLTEDGASFKSCIDESCWTPLDDVSFTYANDSLLVYTKSKTLAEKEVLKYNEYENSSLEVVTLPCGLVGGETLLPYAPTSVEALLSPLTRNLVWFNALKFLQELWGSIALVHIEDICQAHIFCMEKPSMKGRFLCSAANPTISEIAIYFQEKFPEYEIAKEILEGPKQGVKCDSTKLMKMGFEFIYDEKKILDDSVACGRQRGALM
>BPChr02G14579.v1.1.679
MEEKSNSRVCVTGVSGYIGSSLVKKLLEKGYTVHATLRNLGDTSKVDLLNSLPNADKRLVLFEADIYNPTDFESAIKGCEYVFHVATPMLHNTQSSQYKDTAEAAVAGVRTIADSCIRSQTVKRLIYTASMTASSPLTEDGASFKSCIDESCWTPLDDVSFTYANDSLLAYTKSKTLAEKEVLKYNEYENSRLEVVTLPCGLVGGETLLPYVPGSVEAILSPLTSNLSWFNAFKFLQELWGSIALVHIEDVCQAHIFCMEKPSIKGRFLCAATNPTISEIAIYFKEKFPEYEIAKEFFEGPDQGVVRCDSMKLMKMGFEYIYDENKILDDSVACGRRCRALM
>BPChr04G24402.v1.1.679
MSGTGKVVCVTGASGYIASWLVKLLLQRGYTVKATVRDPNDPKKTEHLLAFDGAKERLHLFKANLVEEGSFDSAVNGCEGVFHFHTASPLLLSATDPESWYMVSKTLAEEAAWRFAKENEIDLVTINPRGKKQLISSYSLGAFMHAVAQTFPNSFYRFVDIRDVANAHIQALEVPSTAGRYCLIETVIHCSEVIKILHKLYPTLRLPEKCDDKPSIPGYQVSKEKAKSLGINFIPLEVTLRDTVESLKQKGFFYF
>BPChr04G14229.v1.1.679
MWYALSKTLTERAAWEFCNKNGIDLVTILPSFIVGPSLSLDLCSTAFDVLGLLKGVFYSPLIKLMAVAVVRLY
>BPChr04G24504.v1.1.679
MSGAEKVVCVTGASGYIASGLVKLLLQRGNTIKATVRDPIIHNRRLLTPDVVVDETWFSDPVMCKELKLWYPLSKTLAEEAAWKFAEECGIDLLMGIVYCVSS
MDLDRMWNYSFCKLIGLRFKIDDDWYSVGNINSDTFDDLQVHFSHLLEGTIFDQLDKGVLVLENGWDEIAQEFIEHGSCETTYVGYELINEAIDIDLWWGFRVADDIGKARQGFANVVDHIVKKQIKMGEKSYCRVCVTGASGYIGSWLVKKLLEKGYTVHATLRNLGETSKVDLLKSLPNADNRLVLFQADIYNPTDFEPAIRGCEYVFHVATPMQHYTQSSQYKDTAEAAIAGVRSIADSCIRSQTVKRLIYTASMTASSPLTEDGASFKSCIDESCWTPLDDVSFTYANDSLLVYTKSKTLAEKEVLKYNEYENSSLEVVTLPCGLVGGETLLPYAPTSVEALLSPLTRNLVWFNALKFLQELWGSIALVHIEDICQAHIFCMEKPSMKGRFLCSAANPTISEIAIYFQEKFPEYEIAKEILEGPKQGVKCDSTKLMKMGFEFIYDEKKILDDSVACGRQRGALM
>BPChr02G14579.v1.1.679
MEEKSNSRVCVTGVSGYIGSSLVKKLLEKGYTVHATLRNLGDTSKVDLLNSLPNADKRLVLFEADIYNPTDFESAIKGCEYVFHVATPMLHNTQSSQYKDTAEAAVAGVRTIADSCIRSQTVKRLIYTASMTASSPLTEDGASFKSCIDESCWTPLDDVSFTYANDSLLAYTKSKTLAEKEVLKYNEYENSRLEVVTLPCGLVGGETLLPYVPGSVEAILSPLTSNLSWFNAFKFLQELWGSIALVHIEDVCQAHIFCMEKPSIKGRFLCAATNPTISEIAIYFKEKFPEYEIAKEFFEGPDQGVVRCDSMKLMKMGFEYIYDENKILDDSVACGRRCRALM
>BPChr04G24402.v1.1.679
MSGTGKVVCVTGASGYIASWLVKLLLQRGYTVKATVRDPNDPKKTEHLLAFDGAKERLHLFKANLVEEGSFDSAVNGCEGVFHFHTASPLLLSATDPESWYMVSKTLAEEAAWRFAKENEIDLVTINPRGKKQLISSYSLGAFMHAVAQTFPNSFYRFVDIRDVANAHIQALEVPSTAGRYCLIETVIHCSEVIKILHKLYPTLRLPEKCDDKPSIPGYQVSKEKAKSLGINFIPLEVTLRDTVESLKQKGFFYF
>BPChr04G14229.v1.1.679
MWYALSKTLTERAAWEFCNKNGIDLVTILPSFIVGPSLSLDLCSTAFDVLGLLKGVFYSPLIKLMAVAVVRLY
>BPChr04G24504.v1.1.679
MSGAEKVVCVTGASGYIASGLVKLLLQRGNTIKATVRDPIIHNRRLLTPDVVVDETWFSDPVMCKELKLWYPLSKTLAEEAAWKFAEECGIDLLMGIVYCVSS
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University