Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Acorus americanus
Species name
Sweetflag (Acorus americanus) is a species of monocot in the family Acoraceae (sweet flag family).
Species info
Gene sequence info
Acorus_americanus.COMT.fa
Download
>Acora.02G099400.1.v1.1
MEIPTGEAAKELIEANSFIWNHFLGFAGTMSLKCAVQLGIPDAIDRHGGPITLPELADALSVHPAKTLHLRRLMRTLAHLGFFVKQTREADGEEVYRFATVSKYLLKNHATGMAPGLLMGLDPEWVAPWHSLGDSLRREEPTPFHAMYGKSCWELMAHRPDVNEMFNESMDARLVMEVVVNEYGHVFKGLRSLVDIGGSTGTVAKAIRKAFPYVRCTTFDLPHVIESATRDASINYVGGNMFKHVPPADAILLKWILHDWSDEDCVKILKRCKEAIPMVGGGK
>Acora.07G191400.1.v1.1
MGLTEKHSRTTEEEVDEATCHYSFKLASSSILPMTLKAVLELDLLEIIATAGPGAQLSPAAVASKLPTTNPEAPAMLDRIFRLLASHSVLTCSVVDGEDGKPKRLYGLTPVAKLLTKNEHGMSTAPLVLLNLDRVFLESWLCLKDAVLEGGTPFNKAHGMTSFEYNSTDPRFSKLFNDSMVNHSTTFMKKILGTYKGFDGLSTVVDVGGGVGGSLAMIVSKHPNIRGINFDLPHVIEAAPPIKGVEHVGGDMFESIPQGDAIFLKWILHDWSDQHCVKLLKNCYKALPPSGKVIISEMILPVAPEVDSMVQLTCALDLILLAHFAGGKERTEGEYETLAKKAGFTRINKVCWAVGSSIMEFQK
>Acora.07G193800.1.v1.1
MGSTDHMISRPTEEEEACHYSMILGSSSVLPMTLKAAIELDLLEIIAAAGPGAELSPSDVASKLPTSNPEAPVMLDRILRLLASYSILTCSVVDGEDGKVKRLYGLAPVAKFLTKNEDGVSMAALVLMNQDKVLMESWYYLKDAVLEGGIPFNKAHGTTSFDYHGKDARFNKVFNAGMFNHSTIALKKILDTYKGFDGLSTIVDVGGGVGGTLKMILSKHTTIKGINFDLPHVIEVAPAITGVEHVGGDMFESVPSGDAIFMKWILHDWSDQHCAKLLKNCYKALPPSGKVIIAEMILPEAPETNTAAQGTFHVDLIMLAHNPGGKERTESEFHALAKEAGFTKFNKACCAFNTWVMEFSK
>Acora.07G191600.1.v1.1
MGLTEKLSRTTEEEVDEATCHYSFKLASSSILPMTLKAVLELDLLEIIATAGPGAQLSPAEVASKLPTTNPEAPAMLDRIFRLLASHSVLTCSVVDGEDGKPQRLYGLTPVAKLLTKNEHGMSTAPLVLLNLDRVFLESWLCLKDAVLEGGIPFNKAHGMTSFEYNSRDPRFSKLFNDSMVNHSTNFMKKILGTYKGFDGLSTVVDVGGGVGGSLAMIVSKHPNIRGINFDLPHVIEAAPPIKGVEHVGGDMFESIPQGDAIFLKWILHNWSDQHCVKLLKNCYKALPPSGKVILSEMTLPVAPEVDSIVQLTCALDLTMLAHFAGGKERTEGEYETLAKEAGFTRINKVCWALGNSIMELQK
>Acora.08G062900.1.v1.1
MGSTENINKTREEEEEEACLYSMLLGSASVLPMTLKAAVELDLLEIIAAAGPGAKLSPSEVASKLPTTNPEAPVMLDRILRLLASYSVLTCSAVDGEDGKVKRLYGLAPVAKYLTKNEDGVSMAPLLLMIQDKVLMESWFYLKDAVLEGGIPFNKAHGMTSFEYHGTNPRFNKMFNDGMVNHSTILLKKLLGIYNGFDDLNTLVDVGGTLKMIVSKHPNIKGINFDLPHVTDVAPLIPGVEHVGGDMFESVPTGDAIFMKWILHDWSDQHCLKLLKNCYKALPPSGKVIVVDMILPVTPGSTTQGNFQADVLMLAVNPGGKERIEGEFEALAIEAGFTGFKKVCCVLNTWVMEFYK
>Acora.08G063100.1.v1.1
MGSIENINKTREEEEGEACLYSMLLGSASVLPMTLKAAVELDLLEIVAAAGPGAKLSPSEVASKLPTTNPEAPVMLDRILRLLASYSVLTCSVVDGEDGKVKRLYGLAPVAKYLTKNEDGVSMAPLLLMIQDMVVMESWY
>Acora.08G062400.1.v1.1
MGSTENINNTREAEEEEACLYSMLLGSASVLPMTLKAAVELDLLEIIAAAGPGAKLSPSEVASKLPTTNPEAPVMLDRILRLLASYSVLTCSAAEGENGKVKRLYGLAPVAKYLTKNEDGVSMAPLVLMNQDKVLMESWYYLKDAVLEGGIPFNKAHGMTSFEYHGTDPRFNKVFNDGMVNHSTIFSKKLLDIYNGFDELNTLVDVGGGVGGTLKKIVTKHPNIKGISFDLPH
>Acora.08G063200.1.v1.1
MTSLEYHSTDSRFNKMFNDSMVNHSTIFLKKLLDIYNGFDDLNTLVDVGGGVGGTLKKIVTEHPNIKGINFDLPHVTDAAPPIPGVEHVERDMFESVPTGDAIFMKWILHDWNDQHCLKLLKNCYKALPPSGKVIVVEMILPVTPTSAKQFNFHADVLMLVLNPGGKERTEGEFDALAKEAGFTGFKMVCCALNTWVMEFYK
>Acora.08G178600.1.v1.1
MGSKDQNVSRTIEEVEELACLCSMKLSCITAFPMTLKAALELDLFEIIAAAGPGAQLSPAEVASKLPTTNPEAHVMLDRIFRQLACYSILTCSVVEGEDGKAKRFYGLAPVGKFLTKNEDEVSMAPLVLMNLDKVHMESWYYLKDAVLEGGVAFDKAHGMTSFEYHNSDPRFNKLFSDAMNTPTLFIMKKLLGIYKGFEGLNTLVDVGGSSGRSLKMIISEHPRIRGINFDLPHVIEAAPPIKGVEHVGGDMFESVPSGDAIFMKWILHNWSDQHCVKLLKNCYKALPPSGKIIVLEQILPVAPEPNTIDNAGTSDCDVIMLAQFQGGKERTEGEYEALAKEAGFTGFKKVCWALGNCVMEFHK
>Acora.08G062600.1.v1.1
MIPRTGEKISLDTNPSPLYIQQQQPSLTPNTRQPKKKNTMGSTENISQKTREEEDEEACLYSMILASSSVLPMTLKAAVELDLLEIIAAAGPGAKLSPFEVASKLPTTNPEAPVMLDRILRLLASYSVLTCSVVDGEDGKVKRLYGLAPVAKYLTKNEDGVSMAPLVLMNQDKVLMESWYYLKDAVLEGGIPFNKAHGTTSFEYHGTDPRFNKVFNDGMVNHSTILLKKLLDIYKGFDNLNTLVDVGGGVGGTLKMIVSKHTNIKGINFDLPHVTDVAPLIPGVEHVGGDMFESVPTGDAIFMKWILHDWSDQHCVKLLKNCYKALPPLGKVIVVEMTLPETAGTYPAAQGNFHVDLIMLAHNPGGKERTEAEFEALAKEAGFTGFKKVCFAFNSWVMEFYK
>Acora.08G062300.1.v1.1
MGSIEHNSRTASEEEEEAACLYSMILASSSILPMTLKAAVELDLLEIIAAAGPGAEFSPSEVASQIPTSNPDAPVMLDRILRLLASYKILTCSLVEGEDGKVTRLYGLAPVAKFLTKNQDGVSMAALVLMNQDKVLMESWYYLKDAVLEGGIPFNKAHGTSSFEYHGKDARFNKVFNAGMYNHSTIVMKKLLETYTGFDGLNTVVDVGGGVGGTLKMIVSKHTNIKGINFDLPHVIDDAPAIPGVEHVGGDMFESVPTGDAIFMKWILHDWSDQHCAKLLKNCYKSLPQSGKVIVVELILPEAPETNTAAQSVIHVDLIMLAHNPGGKERTEREYEALAKEAGFTGFKKACCAFNTWVMEFTK
MEIPTGEAAKELIEANSFIWNHFLGFAGTMSLKCAVQLGIPDAIDRHGGPITLPELADALSVHPAKTLHLRRLMRTLAHLGFFVKQTREADGEEVYRFATVSKYLLKNHATGMAPGLLMGLDPEWVAPWHSLGDSLRREEPTPFHAMYGKSCWELMAHRPDVNEMFNESMDARLVMEVVVNEYGHVFKGLRSLVDIGGSTGTVAKAIRKAFPYVRCTTFDLPHVIESATRDASINYVGGNMFKHVPPADAILLKWILHDWSDEDCVKILKRCKEAIPMVGGGK
>Acora.07G191400.1.v1.1
MGLTEKHSRTTEEEVDEATCHYSFKLASSSILPMTLKAVLELDLLEIIATAGPGAQLSPAAVASKLPTTNPEAPAMLDRIFRLLASHSVLTCSVVDGEDGKPKRLYGLTPVAKLLTKNEHGMSTAPLVLLNLDRVFLESWLCLKDAVLEGGTPFNKAHGMTSFEYNSTDPRFSKLFNDSMVNHSTTFMKKILGTYKGFDGLSTVVDVGGGVGGSLAMIVSKHPNIRGINFDLPHVIEAAPPIKGVEHVGGDMFESIPQGDAIFLKWILHDWSDQHCVKLLKNCYKALPPSGKVIISEMILPVAPEVDSMVQLTCALDLILLAHFAGGKERTEGEYETLAKKAGFTRINKVCWAVGSSIMEFQK
>Acora.07G193800.1.v1.1
MGSTDHMISRPTEEEEACHYSMILGSSSVLPMTLKAAIELDLLEIIAAAGPGAELSPSDVASKLPTSNPEAPVMLDRILRLLASYSILTCSVVDGEDGKVKRLYGLAPVAKFLTKNEDGVSMAALVLMNQDKVLMESWYYLKDAVLEGGIPFNKAHGTTSFDYHGKDARFNKVFNAGMFNHSTIALKKILDTYKGFDGLSTIVDVGGGVGGTLKMILSKHTTIKGINFDLPHVIEVAPAITGVEHVGGDMFESVPSGDAIFMKWILHDWSDQHCAKLLKNCYKALPPSGKVIIAEMILPEAPETNTAAQGTFHVDLIMLAHNPGGKERTESEFHALAKEAGFTKFNKACCAFNTWVMEFSK
>Acora.07G191600.1.v1.1
MGLTEKLSRTTEEEVDEATCHYSFKLASSSILPMTLKAVLELDLLEIIATAGPGAQLSPAEVASKLPTTNPEAPAMLDRIFRLLASHSVLTCSVVDGEDGKPQRLYGLTPVAKLLTKNEHGMSTAPLVLLNLDRVFLESWLCLKDAVLEGGIPFNKAHGMTSFEYNSRDPRFSKLFNDSMVNHSTNFMKKILGTYKGFDGLSTVVDVGGGVGGSLAMIVSKHPNIRGINFDLPHVIEAAPPIKGVEHVGGDMFESIPQGDAIFLKWILHNWSDQHCVKLLKNCYKALPPSGKVILSEMTLPVAPEVDSIVQLTCALDLTMLAHFAGGKERTEGEYETLAKEAGFTRINKVCWALGNSIMELQK
>Acora.08G062900.1.v1.1
MGSTENINKTREEEEEEACLYSMLLGSASVLPMTLKAAVELDLLEIIAAAGPGAKLSPSEVASKLPTTNPEAPVMLDRILRLLASYSVLTCSAVDGEDGKVKRLYGLAPVAKYLTKNEDGVSMAPLLLMIQDKVLMESWFYLKDAVLEGGIPFNKAHGMTSFEYHGTNPRFNKMFNDGMVNHSTILLKKLLGIYNGFDDLNTLVDVGGTLKMIVSKHPNIKGINFDLPHVTDVAPLIPGVEHVGGDMFESVPTGDAIFMKWILHDWSDQHCLKLLKNCYKALPPSGKVIVVDMILPVTPGSTTQGNFQADVLMLAVNPGGKERIEGEFEALAIEAGFTGFKKVCCVLNTWVMEFYK
>Acora.08G063100.1.v1.1
MGSIENINKTREEEEGEACLYSMLLGSASVLPMTLKAAVELDLLEIVAAAGPGAKLSPSEVASKLPTTNPEAPVMLDRILRLLASYSVLTCSVVDGEDGKVKRLYGLAPVAKYLTKNEDGVSMAPLLLMIQDMVVMESWY
>Acora.08G062400.1.v1.1
MGSTENINNTREAEEEEACLYSMLLGSASVLPMTLKAAVELDLLEIIAAAGPGAKLSPSEVASKLPTTNPEAPVMLDRILRLLASYSVLTCSAAEGENGKVKRLYGLAPVAKYLTKNEDGVSMAPLVLMNQDKVLMESWYYLKDAVLEGGIPFNKAHGMTSFEYHGTDPRFNKVFNDGMVNHSTIFSKKLLDIYNGFDELNTLVDVGGGVGGTLKKIVTKHPNIKGISFDLPH
>Acora.08G063200.1.v1.1
MTSLEYHSTDSRFNKMFNDSMVNHSTIFLKKLLDIYNGFDDLNTLVDVGGGVGGTLKKIVTEHPNIKGINFDLPHVTDAAPPIPGVEHVERDMFESVPTGDAIFMKWILHDWNDQHCLKLLKNCYKALPPSGKVIVVEMILPVTPTSAKQFNFHADVLMLVLNPGGKERTEGEFDALAKEAGFTGFKMVCCALNTWVMEFYK
>Acora.08G178600.1.v1.1
MGSKDQNVSRTIEEVEELACLCSMKLSCITAFPMTLKAALELDLFEIIAAAGPGAQLSPAEVASKLPTTNPEAHVMLDRIFRQLACYSILTCSVVEGEDGKAKRFYGLAPVGKFLTKNEDEVSMAPLVLMNLDKVHMESWYYLKDAVLEGGVAFDKAHGMTSFEYHNSDPRFNKLFSDAMNTPTLFIMKKLLGIYKGFEGLNTLVDVGGSSGRSLKMIISEHPRIRGINFDLPHVIEAAPPIKGVEHVGGDMFESVPSGDAIFMKWILHNWSDQHCVKLLKNCYKALPPSGKIIVLEQILPVAPEPNTIDNAGTSDCDVIMLAQFQGGKERTEGEYEALAKEAGFTGFKKVCWALGNCVMEFHK
>Acora.08G062600.1.v1.1
MIPRTGEKISLDTNPSPLYIQQQQPSLTPNTRQPKKKNTMGSTENISQKTREEEDEEACLYSMILASSSVLPMTLKAAVELDLLEIIAAAGPGAKLSPFEVASKLPTTNPEAPVMLDRILRLLASYSVLTCSVVDGEDGKVKRLYGLAPVAKYLTKNEDGVSMAPLVLMNQDKVLMESWYYLKDAVLEGGIPFNKAHGTTSFEYHGTDPRFNKVFNDGMVNHSTILLKKLLDIYKGFDNLNTLVDVGGGVGGTLKMIVSKHTNIKGINFDLPHVTDVAPLIPGVEHVGGDMFESVPTGDAIFMKWILHDWSDQHCVKLLKNCYKALPPLGKVIVVEMTLPETAGTYPAAQGNFHVDLIMLAHNPGGKERTEAEFEALAKEAGFTGFKKVCFAFNSWVMEFYK
>Acora.08G062300.1.v1.1
MGSIEHNSRTASEEEEEAACLYSMILASSSILPMTLKAAVELDLLEIIAAAGPGAEFSPSEVASQIPTSNPDAPVMLDRILRLLASYKILTCSLVEGEDGKVTRLYGLAPVAKFLTKNQDGVSMAALVLMNQDKVLMESWYYLKDAVLEGGIPFNKAHGTSSFEYHGKDARFNKVFNAGMYNHSTIVMKKLLETYTGFDGLNTVVDVGGGVGGTLKMIVSKHTNIKGINFDLPHVIDDAPAIPGVEHVGGDMFESVPTGDAIFMKWILHDWSDQHCAKLLKNCYKSLPQSGKVIVVELILPEAPETNTAAQSVIHVDLIMLAHNPGGKERTEREYEALAKEAGFTGFKKACCAFNTWVMEFTK
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University