Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Betula platyphylla
Species name
Asian white birch (Betula platyphylla) is a species of eudicot in the family Betulaceae (birch family).
Species info
Gene sequence info
Betula_platyphylla.4CL.fa
Download
>BPChr01G13758.v1.1.679
SPPTITCSLYISSQPKLKPNQRKDPKLQPNLHLLSFSPHHPKTFLFSSPFPAAKQTSMEPQKDLQEFIFRSKLPDIYIPNHLPLHTYCFENLSQFKDRPCLINGADGVTYTYAQVELTARKVASGLDKLGIKQGEVIMLLLQNCPEFAFAFLGASYIGAVSTTANPFYTPAEVAKQAKASNTKLIITQSSYVDKVKDFAKENGVKVMCIDSPLDDFLHFSQLTQADENDIPAVKINPDDVVALPYSSGTTGLPKGVMLTHRGLVTSVAQQVDGENPNLYFHSGDVILCVLPLFHIYSLNSVFLCGLRVGASILIMQKFEIVKLLELVQQYKVTIAPFVPPIVLAIAKSPDVQWYDVSSIRTVMSGAAPMGRELEDAVRAKLPNAKLGQGYGMTEAGPVLAMCLAFAKEAFEIKSGACGTVVRNAQMKIVDPDTGASLPRNQAGEICIRGSQIMKGYLNDPEATERTIDKDGWLYTGDIGYIDDNDELFIVDRLKELIKYKGFQVAPAELEAMLVAHPNISDAAVVSMKDEAAGEVPVAFVVKSNGSKISEDDIKQYISRQVVFYKRINQVFFTDAIPKAPSGKILRKDLRARLAAGLAN
>BPChr03G18648.v1.1.679
MISVASNSSTEPQNQEFSPKITPGPTQPSETSACVFKSKLPEIPISDHLPLHTYCFEHLAEFSDRPCLIVGSTGKTYSFAETHLVSQKIAAGLSNLGIKKGDVIMVLLQNCAEFVFSFLGASMLGAVTTTANPFYTSAEVFKQLNSSKAKLIITQSQYVDKLREIGENFPKLGEDFTVITVDDPPEKCLHFSVISEANEGEFSSSTVSIDPDDPVALPFSSGTTGLPKGVVLTHKSLITSVAQQVDGENPNLYLNPDDVVLCVLPLFHIYSLNSVLLCSLRAGAAVLLMQKFEIGALLELIQRHRVSVAAVVPPLVLALAKNPVVANFDLSSIRVVLSGAAPLGKELEEALRNRVPQATLGQGYGMTEAGPVLSMCLGFAKQPYPTKSGSCGTVVRNAELKVIDPETGCSLGHNQPGEICIRGSQIMKGYLNDDAATATTIDVEGWLHTGDIGFVDDDDEIFIVDRVKELIKFKGFQAYGLCILKDGDRVMSDGIRVPPAELEALLVSHPSIADAAVVPQKDDVAGEFPVAFVVRSNDFELTEEAVKEFIAKQVVFYKRLHKVYFVHAIPKSPSGKILRKDLRAKLATASPVP
>BPChr05G17489.v1.1.679
MATTSTSLFNCHITEKQSTQIQQNPKPHPHWYSPETGIYHSKHPSLELPSDPYLDVVSFVFSHQHNGVSALIDSSSGSSISFPELYPLVKSMASGLHNTGISKAFTVPEKVEKLQALGVPAIGVPENVNFDSKKQTTFSAFYKLIYGSFDLAPRPMIKQQDTAAIMYSSGTTGMSKGLLYLGSSVVVMRKFNINAVIKALDRYKVTHFPVVPPILTALTREVKNVGGSSLKSLKQVSCGAAPLSRKVIEDFIQTLPHVDFIQGYGMTESTAVGTRGFNTEKFQNYYSIGLLAPNMQAKVVDWNTGSFSPPGSSGELWLRGPAIMKGYLNNVEATMSTIDKDGWLHTGDLVCFDQEGYIHIFDRLKEIINALDEKSGEVPVAFVVRKNGSRLSAEAVMDYVSEQVAPYRKVRKVVFTNTIPKSAAGKILRRELRNFMTSRL
>BPChr06G30307.v1.1.679
MAKSFNPKTQTYSSPRPPIHLPANPNLSLASFLFQSTSSFPHTLALIDADSGETLTFYQLKLQVTKLAHSLIQLNIDKDDVVLIIAPNSIHFPVCFLAIAALGAVVSTCNPSYTISELSKQVSDCNPKLLITVPELWHKIEEFNLPSIILSSSKSKIVSNPKIWYYSELIKSNRDCDLPEKTVKQSDTAALLYSSGTTGKSKGVILTHKNFIAMSMMVTADQDRYGEPKNVYLCFLPMFHVFGLSAITYSQLRRGNTVVSMGKFEFEKFLGAVEKYRVTYLSVVPPVMILLAKHSAVKKYDLSSLKRISSGAAPLGKDVMEECGKNIPQAKITQGYGLTEACGVISTENPLEESRFSGSTGTLASGVESQIVSTDTLKPLPPNQMGEIWVRGPNMMQGYLNNPEATKLTIDGQGWVHTGDLGYFNEEGQLFVVDRIKELIKCYGFQVAPAELEGLLLSHNEILDAVVIPFPNTKAGEVPIAYVVRSPNSLLTEEDVQQFIAKQGNAIVESGRSFIEKLLI
>BPChr06G02182.v1.1.679
MAIQAKEQEFIFRSKLPDIYIPKHLPIHSYCFENISKVGSRPCLINGLTGKVYTYYDVELTARKVASGLSKLGIQKGDVVMLLLPNSPEFAFVFLGASYLGAMTTAANPFCTAGEVSKQAKSANAKIVVTQACYYDRVKDYTNENGVKIICIDSPPEDCLHFSELTKADENDVAEVDISPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYYHSEDVILCVLPLFHIYSLNSVFLCGLRAGASILILPKFEIVSLLQLIQKHKVTVMPIVPPIVLAITKFPDLDKYDLSSVKMLKSGGAPLGKEIEETVKAKFPNALFGQGYGMTEAGPVLAMCLAFAKEPMEVKSGACGTVVRNAEMKIVDPETGASLPRNQPGEICIRGDQIMKGYINDPEATASTIDKEGWLHTGDIGLIDDNDELFIVDRLKELIKYKGFQVAPAELEALLLTHPNISDAAVVPMKDDLAGEVPVAFVARSNGSQVTEDEIKQFVSKQVVFYKRISRVFFIDVVPKSPSGKILRKELRAKLAAGFSN
>BPChr06G30216.v1.1.679
MAKSFNPKTQTYSSPRPPIHLPANPNLSLASFLFQSTSSFPHTLALIDADSGETLTFYQLKLQVTKLAHSLIQLNIDKDDVVLIIAPNSIHFPVCFLAIAALGAVVSTCNPSYTISELSKQVSDCNPKLLITVPELWHKIEEFNLPSIILSSSKSKIVSNPKIWYYSELIKSNRDCDLPEKTVKQSDTAALLYSSGTTGKSKGVILTHKNFIAMSMMVTADQDRYGEPKNVYLCFLPMFHVFGLSAITYSQLRRGNTVVSMGKFEFEKFLGAVEKYRVTYLSVVPPVMILLAKHSAVKKYDLSSLKRISSGAAPLGKDVMEECGKNIPQAKITQGYGLTEACGVISTENPLEESRFSGSTGTLASGVESQIVSTDTLKPLPPNQMGEIWVRGPNMMQGYLNNPEATKLTIDGQGWVHTGDLGYFNEEGQLFVVDRIKELIKCYGFQVAPAELEGLLLSHNEILDAVVIPFPNTKAGEVPIAYVVRSPNSLLTEEDVQQFIAKQGNAIVESGRSFIEKLLI
>BPChr08G03069.v1.1.679
MIVTNLELILLIKHGRYLLDPLSIHIFIMGTNAQNLAGDDEHIFRSRFPAVQVPDITLPEFVLQDAESYASKVAFVEAVTGKEVTYGDVVRDTRRFSKALRSLGLSKGDAVIVVLPNVAEYAIVALGIMAAGGVFSGANPTAHASEIRKQVEAAEAKLIVTNGPSYEKVKGLGLPTIILGEELIEGAMNWNKLLEAADRAGASSVKVEVQPTDLCALPFSSGTTGLSKGVMLTHRNLVANLCSTLFGVAPELVGHVTTLGLIPFFHIYGITGICCATLRNKGKVVVMGRFELRTFMNALITQEVTFAPIVPPIILQLVKNPVVEEFDLSKLKLQAVMSAAAPLAPEVLTAFENKFPGVQVQEAYGLTEHSCITLTLADPQTGSRLAKKSSVGFILPNLEVKFIDPDTGRSLPSNTPGEICVRSECVMQGYYNNEEETARTIDKQGWLHSGDIGFIDDEGNIFIVDRIKELIKYKGFQVAPAELEAILLTHPSIEDAAVVPLPDDEAGEIPAASIVLTPGGNESEEDVINYVASNVAHYKKVRVVHFVETIPKSPSGKIMRRLIREKMIEKMRANIHS
>BPChr10G06584.v1.1.679
MEKSGYGRDGIYRSVRPPLVLPKDPNLSMVTFLFRNSSSYPHKPALIDADSSQTLSFSQFKSTVATISRGFLGLGITKNDVVLIFAPNSIQFPLCFLGIVAIGAIATTANPLYTVHELARQVKDSNPKLIITVPELWDKVKNFNLPAVFLGSNHSSSSSNVIHFDDLVNLGGTWSGSGSGSDFPDSNVKQNDTAALLYSSGTTGMSKGVILTHGNFIAASLMVSMDQELSGEAHNVFLCVLPMFHVFGLAVILYSQLQIGNAVVSMGRFELEKILRAVERYRVSHLWVVPPIILALAKQDVVKKYDLASLKHVGSGAAPLGKDLMEECARNIPQAVVAQGYGMTETCGIVSVENPRIGARNTGSAGLLAPGVESQIVSVDALKPLPPNQLGEIWVRGPNMMQGYYNNPQATKLTIDKQGWVHTGDLGYFDGDGHLYVVDRIKELIKYKGFQVAPAELEGLLISHPEILDAVVIPFPDAEAGEVPIAYVVRSPNSSLTEVDAMKFIANQVAPFKRLRRVTFINKVPKSASGKILRRELIEKVGSKM
SPPTITCSLYISSQPKLKPNQRKDPKLQPNLHLLSFSPHHPKTFLFSSPFPAAKQTSMEPQKDLQEFIFRSKLPDIYIPNHLPLHTYCFENLSQFKDRPCLINGADGVTYTYAQVELTARKVASGLDKLGIKQGEVIMLLLQNCPEFAFAFLGASYIGAVSTTANPFYTPAEVAKQAKASNTKLIITQSSYVDKVKDFAKENGVKVMCIDSPLDDFLHFSQLTQADENDIPAVKINPDDVVALPYSSGTTGLPKGVMLTHRGLVTSVAQQVDGENPNLYFHSGDVILCVLPLFHIYSLNSVFLCGLRVGASILIMQKFEIVKLLELVQQYKVTIAPFVPPIVLAIAKSPDVQWYDVSSIRTVMSGAAPMGRELEDAVRAKLPNAKLGQGYGMTEAGPVLAMCLAFAKEAFEIKSGACGTVVRNAQMKIVDPDTGASLPRNQAGEICIRGSQIMKGYLNDPEATERTIDKDGWLYTGDIGYIDDNDELFIVDRLKELIKYKGFQVAPAELEAMLVAHPNISDAAVVSMKDEAAGEVPVAFVVKSNGSKISEDDIKQYISRQVVFYKRINQVFFTDAIPKAPSGKILRKDLRARLAAGLAN
>BPChr03G18648.v1.1.679
MISVASNSSTEPQNQEFSPKITPGPTQPSETSACVFKSKLPEIPISDHLPLHTYCFEHLAEFSDRPCLIVGSTGKTYSFAETHLVSQKIAAGLSNLGIKKGDVIMVLLQNCAEFVFSFLGASMLGAVTTTANPFYTSAEVFKQLNSSKAKLIITQSQYVDKLREIGENFPKLGEDFTVITVDDPPEKCLHFSVISEANEGEFSSSTVSIDPDDPVALPFSSGTTGLPKGVVLTHKSLITSVAQQVDGENPNLYLNPDDVVLCVLPLFHIYSLNSVLLCSLRAGAAVLLMQKFEIGALLELIQRHRVSVAAVVPPLVLALAKNPVVANFDLSSIRVVLSGAAPLGKELEEALRNRVPQATLGQGYGMTEAGPVLSMCLGFAKQPYPTKSGSCGTVVRNAELKVIDPETGCSLGHNQPGEICIRGSQIMKGYLNDDAATATTIDVEGWLHTGDIGFVDDDDEIFIVDRVKELIKFKGFQAYGLCILKDGDRVMSDGIRVPPAELEALLVSHPSIADAAVVPQKDDVAGEFPVAFVVRSNDFELTEEAVKEFIAKQVVFYKRLHKVYFVHAIPKSPSGKILRKDLRAKLATASPVP
>BPChr05G17489.v1.1.679
MATTSTSLFNCHITEKQSTQIQQNPKPHPHWYSPETGIYHSKHPSLELPSDPYLDVVSFVFSHQHNGVSALIDSSSGSSISFPELYPLVKSMASGLHNTGISKAFTVPEKVEKLQALGVPAIGVPENVNFDSKKQTTFSAFYKLIYGSFDLAPRPMIKQQDTAAIMYSSGTTGMSKGLLYLGSSVVVMRKFNINAVIKALDRYKVTHFPVVPPILTALTREVKNVGGSSLKSLKQVSCGAAPLSRKVIEDFIQTLPHVDFIQGYGMTESTAVGTRGFNTEKFQNYYSIGLLAPNMQAKVVDWNTGSFSPPGSSGELWLRGPAIMKGYLNNVEATMSTIDKDGWLHTGDLVCFDQEGYIHIFDRLKEIINALDEKSGEVPVAFVVRKNGSRLSAEAVMDYVSEQVAPYRKVRKVVFTNTIPKSAAGKILRRELRNFMTSRL
>BPChr06G30307.v1.1.679
MAKSFNPKTQTYSSPRPPIHLPANPNLSLASFLFQSTSSFPHTLALIDADSGETLTFYQLKLQVTKLAHSLIQLNIDKDDVVLIIAPNSIHFPVCFLAIAALGAVVSTCNPSYTISELSKQVSDCNPKLLITVPELWHKIEEFNLPSIILSSSKSKIVSNPKIWYYSELIKSNRDCDLPEKTVKQSDTAALLYSSGTTGKSKGVILTHKNFIAMSMMVTADQDRYGEPKNVYLCFLPMFHVFGLSAITYSQLRRGNTVVSMGKFEFEKFLGAVEKYRVTYLSVVPPVMILLAKHSAVKKYDLSSLKRISSGAAPLGKDVMEECGKNIPQAKITQGYGLTEACGVISTENPLEESRFSGSTGTLASGVESQIVSTDTLKPLPPNQMGEIWVRGPNMMQGYLNNPEATKLTIDGQGWVHTGDLGYFNEEGQLFVVDRIKELIKCYGFQVAPAELEGLLLSHNEILDAVVIPFPNTKAGEVPIAYVVRSPNSLLTEEDVQQFIAKQGNAIVESGRSFIEKLLI
>BPChr06G02182.v1.1.679
MAIQAKEQEFIFRSKLPDIYIPKHLPIHSYCFENISKVGSRPCLINGLTGKVYTYYDVELTARKVASGLSKLGIQKGDVVMLLLPNSPEFAFVFLGASYLGAMTTAANPFCTAGEVSKQAKSANAKIVVTQACYYDRVKDYTNENGVKIICIDSPPEDCLHFSELTKADENDVAEVDISPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYYHSEDVILCVLPLFHIYSLNSVFLCGLRAGASILILPKFEIVSLLQLIQKHKVTVMPIVPPIVLAITKFPDLDKYDLSSVKMLKSGGAPLGKEIEETVKAKFPNALFGQGYGMTEAGPVLAMCLAFAKEPMEVKSGACGTVVRNAEMKIVDPETGASLPRNQPGEICIRGDQIMKGYINDPEATASTIDKEGWLHTGDIGLIDDNDELFIVDRLKELIKYKGFQVAPAELEALLLTHPNISDAAVVPMKDDLAGEVPVAFVARSNGSQVTEDEIKQFVSKQVVFYKRISRVFFIDVVPKSPSGKILRKELRAKLAAGFSN
>BPChr06G30216.v1.1.679
MAKSFNPKTQTYSSPRPPIHLPANPNLSLASFLFQSTSSFPHTLALIDADSGETLTFYQLKLQVTKLAHSLIQLNIDKDDVVLIIAPNSIHFPVCFLAIAALGAVVSTCNPSYTISELSKQVSDCNPKLLITVPELWHKIEEFNLPSIILSSSKSKIVSNPKIWYYSELIKSNRDCDLPEKTVKQSDTAALLYSSGTTGKSKGVILTHKNFIAMSMMVTADQDRYGEPKNVYLCFLPMFHVFGLSAITYSQLRRGNTVVSMGKFEFEKFLGAVEKYRVTYLSVVPPVMILLAKHSAVKKYDLSSLKRISSGAAPLGKDVMEECGKNIPQAKITQGYGLTEACGVISTENPLEESRFSGSTGTLASGVESQIVSTDTLKPLPPNQMGEIWVRGPNMMQGYLNNPEATKLTIDGQGWVHTGDLGYFNEEGQLFVVDRIKELIKCYGFQVAPAELEGLLLSHNEILDAVVIPFPNTKAGEVPIAYVVRSPNSLLTEEDVQQFIAKQGNAIVESGRSFIEKLLI
>BPChr08G03069.v1.1.679
MIVTNLELILLIKHGRYLLDPLSIHIFIMGTNAQNLAGDDEHIFRSRFPAVQVPDITLPEFVLQDAESYASKVAFVEAVTGKEVTYGDVVRDTRRFSKALRSLGLSKGDAVIVVLPNVAEYAIVALGIMAAGGVFSGANPTAHASEIRKQVEAAEAKLIVTNGPSYEKVKGLGLPTIILGEELIEGAMNWNKLLEAADRAGASSVKVEVQPTDLCALPFSSGTTGLSKGVMLTHRNLVANLCSTLFGVAPELVGHVTTLGLIPFFHIYGITGICCATLRNKGKVVVMGRFELRTFMNALITQEVTFAPIVPPIILQLVKNPVVEEFDLSKLKLQAVMSAAAPLAPEVLTAFENKFPGVQVQEAYGLTEHSCITLTLADPQTGSRLAKKSSVGFILPNLEVKFIDPDTGRSLPSNTPGEICVRSECVMQGYYNNEEETARTIDKQGWLHSGDIGFIDDEGNIFIVDRIKELIKYKGFQVAPAELEAILLTHPSIEDAAVVPLPDDEAGEIPAASIVLTPGGNESEEDVINYVASNVAHYKKVRVVHFVETIPKSPSGKIMRRLIREKMIEKMRANIHS
>BPChr10G06584.v1.1.679
MEKSGYGRDGIYRSVRPPLVLPKDPNLSMVTFLFRNSSSYPHKPALIDADSSQTLSFSQFKSTVATISRGFLGLGITKNDVVLIFAPNSIQFPLCFLGIVAIGAIATTANPLYTVHELARQVKDSNPKLIITVPELWDKVKNFNLPAVFLGSNHSSSSSNVIHFDDLVNLGGTWSGSGSGSDFPDSNVKQNDTAALLYSSGTTGMSKGVILTHGNFIAASLMVSMDQELSGEAHNVFLCVLPMFHVFGLAVILYSQLQIGNAVVSMGRFELEKILRAVERYRVSHLWVVPPIILALAKQDVVKKYDLASLKHVGSGAAPLGKDLMEECARNIPQAVVAQGYGMTETCGIVSVENPRIGARNTGSAGLLAPGVESQIVSVDALKPLPPNQLGEIWVRGPNMMQGYYNNPQATKLTIDKQGWVHTGDLGYFDGDGHLYVVDRIKELIKYKGFQVAPAELEGLLISHPEILDAVVIPFPDAEAGEVPIAYVVRSPNSSLTEVDAMKFIANQVAPFKRLRRVTFINKVPKSASGKILRRELIEKVGSKM
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University