Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Benincasa hispida
Species name
Wax gourd (Benincasa hispida) is a species of eudicot in the family Cucurbitaceae (cucumber family).
Species info
Gene sequence info
Benincasa_hispida.CHS.fa
Download
>Bhi01M001520
MASVVAEIRKAQRADGPAMVLAIGTTAPLNIVLQSDYPDYYFHITNSEDLTHLKQKFTRICENSMIRKRHMYLTEEILRENPNMCAYMAHSLDTRQDIAVVEVPKLGKDAAEKAIKEWGQPKSKITHLIFCTSSGIDMPGADFQLLKLLGLRPSVKRYMIYQQGCFAGGTGIRLAKDLAENNRGARVLVVCSEISAMKFRGPSEIHLDTMIGQALFGDGAAAVIIGTDPDVSVEHPLYELVWTGATLVPDSEGAIEGHLREVGLTCHLLKDVPGLISNNIEKSLKEAFTPLGISDWNSIFWIFHPGGPAILDQVEAKLGLKEEKMRATREVLREYGNMSSVSVLFIMDQMRKNSIEEENSTTGEGLEWGVLFGFGPGITLETVVLHSIDIKETTMKAASH
>Bhi01M001402
MASVVAEIRKAQRADGPATVLAIGTATPPHSVLQSDYPDYYFRITNSEHMTHLKEKFTRMCEKSMIRKRHMYLTEEILRENPNMCAYMAPSLDARQDIVVVEVPKLGKDAAAKAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLLKLLGLRPSVKRYMMYQQGCFAGATVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSETHLDSMVGQALFGDGAAAVIIGSDPDVTVERPLYELVWTGATVVPDSEGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLKEAFTPLGISDWNSIFWIAHPGGPAILDQVEGKLGLKEEKMRATREVLSEYGNMSSACVLFIMDQMRKNSVEEGNSTTGEGLEWGVLFGFGPGLTVETVVLHSIDIKETTLEVASH
>Bhi01M000425
MSRMSCEGSAMLDHPRARRVPTPRTATILALGKAFPSQLVPQECLVEGYIRDTKCVDATIKEKLERLCKTTTVKTRYTVMCKEILDKYPELVTEGSPTIRQRLEIANPAVVEMATEASKACIKEWGRSVEDITHIVYVSSSEIRLPGGDLYIANRLGLKNDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRILLMTSETTILGFRPPNNARPYDLVGAALFGDGAAAVIIGADPVPGQESPFMELNYAVQQFLPDTHNVIDGRLSEEGINFKLGRDLPQRIDDNIEDFCRKLMGKGRLVDFNDLFWVVHPGGPAILNKLENTLRLKSGKLECSRKALMDYGNVSSNTIFYVIENMRENLKREDGEEWGLALAFGPGITFEGILIRSL
>Bhi04M001475
MHPQLELLANDYNNSLFYAIHPGGRAIIDEIEQKLGLEKTKLDVSRKVLREYGNKTGPTVIFISDEMIIDMQYLFYYLMLESMNEY
>Bhi12M001320
MATVDEILKGQRAEGVASVLAIGTAVPSNCIEQSTYPDYYFRITNNEHKTELKQKFKRMCEKSKIERRYMLLTEEILKANPKICAYEAPSLDSRQDIAIVEVPKLGKQAAVNALRQWGRPTADITHLIFCTSSGVDMPGADYRLTNLLGLRPSVKRFMIYQQGCFAGATVLRLLKDLAENNRSARVLAVCSEITAVTFRGPSESHLDSLVGQALFGDGAAAIIVGSDPIPGLERPIFEIISAGQTILPDSDGAIDGHLREVGLTFHLLKDVPALVSNNIRRTLVEAFGPLGLSTDWNSIFWIVHPGGPAILDQIEMELGLEPEKLRASRHVLREYGNMSSACVLFILDEMRKKSIQNGDKTTGEGLEWGVLFGFGPGLTVETVVLRSVPI
MASVVAEIRKAQRADGPAMVLAIGTTAPLNIVLQSDYPDYYFHITNSEDLTHLKQKFTRICENSMIRKRHMYLTEEILRENPNMCAYMAHSLDTRQDIAVVEVPKLGKDAAEKAIKEWGQPKSKITHLIFCTSSGIDMPGADFQLLKLLGLRPSVKRYMIYQQGCFAGGTGIRLAKDLAENNRGARVLVVCSEISAMKFRGPSEIHLDTMIGQALFGDGAAAVIIGTDPDVSVEHPLYELVWTGATLVPDSEGAIEGHLREVGLTCHLLKDVPGLISNNIEKSLKEAFTPLGISDWNSIFWIFHPGGPAILDQVEAKLGLKEEKMRATREVLREYGNMSSVSVLFIMDQMRKNSIEEENSTTGEGLEWGVLFGFGPGITLETVVLHSIDIKETTMKAASH
>Bhi01M001402
MASVVAEIRKAQRADGPATVLAIGTATPPHSVLQSDYPDYYFRITNSEHMTHLKEKFTRMCEKSMIRKRHMYLTEEILRENPNMCAYMAPSLDARQDIVVVEVPKLGKDAAAKAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLLKLLGLRPSVKRYMMYQQGCFAGATVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSETHLDSMVGQALFGDGAAAVIIGSDPDVTVERPLYELVWTGATVVPDSEGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLKEAFTPLGISDWNSIFWIAHPGGPAILDQVEGKLGLKEEKMRATREVLSEYGNMSSACVLFIMDQMRKNSVEEGNSTTGEGLEWGVLFGFGPGLTVETVVLHSIDIKETTLEVASH
>Bhi01M000425
MSRMSCEGSAMLDHPRARRVPTPRTATILALGKAFPSQLVPQECLVEGYIRDTKCVDATIKEKLERLCKTTTVKTRYTVMCKEILDKYPELVTEGSPTIRQRLEIANPAVVEMATEASKACIKEWGRSVEDITHIVYVSSSEIRLPGGDLYIANRLGLKNDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRILLMTSETTILGFRPPNNARPYDLVGAALFGDGAAAVIIGADPVPGQESPFMELNYAVQQFLPDTHNVIDGRLSEEGINFKLGRDLPQRIDDNIEDFCRKLMGKGRLVDFNDLFWVVHPGGPAILNKLENTLRLKSGKLECSRKALMDYGNVSSNTIFYVIENMRENLKREDGEEWGLALAFGPGITFEGILIRSL
>Bhi04M001475
MHPQLELLANDYNNSLFYAIHPGGRAIIDEIEQKLGLEKTKLDVSRKVLREYGNKTGPTVIFISDEMIIDMQYLFYYLMLESMNEY
>Bhi12M001320
MATVDEILKGQRAEGVASVLAIGTAVPSNCIEQSTYPDYYFRITNNEHKTELKQKFKRMCEKSKIERRYMLLTEEILKANPKICAYEAPSLDSRQDIAIVEVPKLGKQAAVNALRQWGRPTADITHLIFCTSSGVDMPGADYRLTNLLGLRPSVKRFMIYQQGCFAGATVLRLLKDLAENNRSARVLAVCSEITAVTFRGPSESHLDSLVGQALFGDGAAAIIVGSDPIPGLERPIFEIISAGQTILPDSDGAIDGHLREVGLTFHLLKDVPALVSNNIRRTLVEAFGPLGLSTDWNSIFWIVHPGGPAILDQIEMELGLEPEKLRASRHVLREYGNMSSACVLFILDEMRKKSIQNGDKTTGEGLEWGVLFGFGPGLTVETVVLRSVPI
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University