Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Begonia fuchsioides
Species name
Begonia fuchsioides is a species of eudicot in the family Begoniaceae (begonia family).
Species info
Gene sequence info
Begonia_fuchsioides.COMT.fa
Download
>Begfu20S02086
MSKICGFVYYMMHLKDAIIEGGNQFREVHGMSVFQYMDVDPEFNKLFNKAMADVSTVVMTRFVEKYEGLKDFCSSVLVDVGGGTGRCLNMIISKYPQIKGINFDLPHLAQSAPSYPGRTNL
>Begfu1480S07939
MADVSTVVMTRFVEKYEGFKDLGSSVLVDVGGGTGRCLNMIISKYPQIKGISFDIHHVAQSAPSFPGVQRVGGDMFSSIPKGNAIMIKTMLHHWDDEKILRRCHEALPEKGKVIIIDMKIPEEPDISEASQHISCLDIMMMMQFDGQERTATEFERLCLKSGFRDFQVVCSVFQVYFAMEFFK
>Begfu1480S07940
MGEEEEACIKAMLVSTSDVLPMVLKAAIDLNLFNLLLAEKGPRSAAEIAAMLPTKAPDTAASRLDRLLHHLASHSLLSWSRRDVGNGRVEVVYGLRPESHFYLAENEKGSFASMLALACHPAIRETWMHLKDAIIEGGNQFRKVHGMSVFQYMDVDPEFNKLFNKAMADLSTVVMSRFVEKYEGFKDLGSSVLVDVGGGTGRCINMIISKYPQIKGISFDLPHVAQSAPSYPGVQQVGGDMFSSIPKGNAIMIKNTLHNWDDENCIKILKRCHEALPEKGKVIIIDMIIPEEPDISMAAQYISSIDITMLMQPNGQERTATEFERLCFKSGFRHFQVVCSVFQVYFALEFSK
>Begfu1480S07941
MGEEEEMCIKAMVISTSDVLPMVLKAAIDLNLFDLLLAENGPKSAAEIAAMLPTKAPDNAASRLDRVLHHLASHSLLSWSRRDVENGRVEVVYGLRPESHIFLSENEKGSLASFFALADHPAIKETWKHLKAAIIEGGNQFRKVHGMSVFQYMEVDPEFHKLFNKAMADVSTVVMTRCLNMIISKYPQIKGISFDLPHVAQSAPSYPGVQQVGGDMFSSIPKGNAIMIKNTLHNWDDENCLKILRRCHEALPEKGRVLIIDMIIPEEPDISMGSQYISSLDLTMLMQLDGQERTATEFETLCFKSGFREFKVVCSVFQVYFAMEFSK
>Begfu1480S19736
MGEEEEACIQAMLVSTSNVLPMVLKAAIDLHLFNLLLLAEKAPKSAAEIATMLLTKAPDTAASRLDRLLHHLASHSLLMHLKDAIIEGLQNVIKPLPFLDKSIFYILENMHANNNLIGNLPSELGSLSNLKVLQLQSNELAGAILTQITELKKLSILNVSWNFLNGSIPPTISNLQKLFKLNLQGNKLSGLIPDSISSMNSLLELQLSTNELRSPIPRMPASLKIALILSSNHFEGQIPHALDRLATLEVMDLSNNKFQGEIPEFMTQMSSMTHLTLSNNNLTGITPKFKPRVEVETSGNPYLINTTTTDSVLFVRRRKIDAHHYNCSCSLYPLIMFSEGQVFFNLVVHFALGFCITSRGSSSE
>Begfu2335S26179
MEGEAGESRNKARLAILELANMISVPLSLNAIVRLNVADAIWDGGANAPLSAQQILTRILPSDGDAENLQRLLRILASYGVFTEHLSNSDDRKYSLTEIGKTLVNNSDGVSYAPYVLQHHQISLNIHRLRVQDELIRSWPLLHEAITDPTTEPFAKANGEPAYSFYGKKPEMNELMQKAMSGTSVPFMNAMLAEYDGFNGVERIVDVGGSGGDCLRMILHRHPDIKEGINFDLPEVVAKAPIIPRVTHVGGDMFRSIPKADAIFMKWILSTWTDDECTSLLENCHRALPAGGKLIACEPVVPRESDSSMRTRALLENDVFVMAIYRAKGKNRTRQEFEKLGRSAGFPTFRVLEIDYFYTVMEFQK
>Begfu8797S42818
MGSAGETQTTPTQVSDEEANLFAMQLASASVLPMVLKAAIELNLLEIVARAGPGALLSPSEIAEQLPTTNPDAAVMLDRMLRLLASYSVLTYSLRTLPDGRVERLYGLAPVCKFLIRNEDAVSIAPLVLMNQDKVLMESWYHLKDAVLEGGIPFNRAYGMTAFDYHGTDPRFNKVFNRGMSDHSTITMKKILETYRGFEGVGSVVDVGGGTGAVISMILSKYPSIKGINFDLPHVIEDAPEYPGVEHVGGDMFVSVPKGDAIFMKWICHDWSDQHCLKLLKNCYEALPRKGKVIVAECILPVAPDSSLATKGVMHIDVIMLAHNPGGKERTQEEFQALAEGAGFQGFRVECCAFNTYVMEFLKSV
>Begfu91244S51206
MASPEIIPDDGEETFSYAVQLSMSSLLPMSLYAAVELGVFEIIANAGPNAGLSSADIAAKLATQNPQSASMLDRILCLLASHSVLHCSQATDANGHLRRVYSLAPVAKFFVRDEDGVALGPFQALVQSKLFLESWSEMKSAVLEGGIPFNKVHGCYSYEYPAKDEHFNEIFNSAMFNYTTIVTKKVLQTYNGFGGIGKLVDVGGGLGTTLSMITSKYPSIKGVNFDLPHVIARAPEYPGVEHVGGDMFESVPRGDAIFLKWILHNWSDEHCLKVLKNCFAALPDAGNVIVVEAIVPNMPETTAACRSMCAMDVQMMTQFSGGKERSREEFTALAIGAGFNGVRFRCFVSNFWIMEFFK
>Begfu91231S43318
MLHSHINTKYLLMTLDSVALSPWQELSKWFHSDYLTAFEMLSGRNFYGHFPDNPEFAKLFNEAMMWDSKMISIALVGECKEVFEGLKSLVDVAGGSGAMMEAIAEAFPHIHCTVLDLPHAIAEKKGRKNMEFVSGDMFEAIPSANAVLLKWVIHNWDDEKSIEILKNCKKAIPSKEEGGKVIIIDMRFDEVTTLDSKIVSIALVEECEEVFEGLKSLANVAGGSRARMEALAEAFPHFHCTLLDLPHAIAEKKGSKNLEF
MSKICGFVYYMMHLKDAIIEGGNQFREVHGMSVFQYMDVDPEFNKLFNKAMADVSTVVMTRFVEKYEGLKDFCSSVLVDVGGGTGRCLNMIISKYPQIKGINFDLPHLAQSAPSYPGRTNL
>Begfu1480S07939
MADVSTVVMTRFVEKYEGFKDLGSSVLVDVGGGTGRCLNMIISKYPQIKGISFDIHHVAQSAPSFPGVQRVGGDMFSSIPKGNAIMIKTMLHHWDDEKILRRCHEALPEKGKVIIIDMKIPEEPDISEASQHISCLDIMMMMQFDGQERTATEFERLCLKSGFRDFQVVCSVFQVYFAMEFFK
>Begfu1480S07940
MGEEEEACIKAMLVSTSDVLPMVLKAAIDLNLFNLLLAEKGPRSAAEIAAMLPTKAPDTAASRLDRLLHHLASHSLLSWSRRDVGNGRVEVVYGLRPESHFYLAENEKGSFASMLALACHPAIRETWMHLKDAIIEGGNQFRKVHGMSVFQYMDVDPEFNKLFNKAMADLSTVVMSRFVEKYEGFKDLGSSVLVDVGGGTGRCINMIISKYPQIKGISFDLPHVAQSAPSYPGVQQVGGDMFSSIPKGNAIMIKNTLHNWDDENCIKILKRCHEALPEKGKVIIIDMIIPEEPDISMAAQYISSIDITMLMQPNGQERTATEFERLCFKSGFRHFQVVCSVFQVYFALEFSK
>Begfu1480S07941
MGEEEEMCIKAMVISTSDVLPMVLKAAIDLNLFDLLLAENGPKSAAEIAAMLPTKAPDNAASRLDRVLHHLASHSLLSWSRRDVENGRVEVVYGLRPESHIFLSENEKGSLASFFALADHPAIKETWKHLKAAIIEGGNQFRKVHGMSVFQYMEVDPEFHKLFNKAMADVSTVVMTRCLNMIISKYPQIKGISFDLPHVAQSAPSYPGVQQVGGDMFSSIPKGNAIMIKNTLHNWDDENCLKILRRCHEALPEKGRVLIIDMIIPEEPDISMGSQYISSLDLTMLMQLDGQERTATEFETLCFKSGFREFKVVCSVFQVYFAMEFSK
>Begfu1480S19736
MGEEEEACIQAMLVSTSNVLPMVLKAAIDLHLFNLLLLAEKAPKSAAEIATMLLTKAPDTAASRLDRLLHHLASHSLLMHLKDAIIEGLQNVIKPLPFLDKSIFYILENMHANNNLIGNLPSELGSLSNLKVLQLQSNELAGAILTQITELKKLSILNVSWNFLNGSIPPTISNLQKLFKLNLQGNKLSGLIPDSISSMNSLLELQLSTNELRSPIPRMPASLKIALILSSNHFEGQIPHALDRLATLEVMDLSNNKFQGEIPEFMTQMSSMTHLTLSNNNLTGITPKFKPRVEVETSGNPYLINTTTTDSVLFVRRRKIDAHHYNCSCSLYPLIMFSEGQVFFNLVVHFALGFCITSRGSSSE
>Begfu2335S26179
MEGEAGESRNKARLAILELANMISVPLSLNAIVRLNVADAIWDGGANAPLSAQQILTRILPSDGDAENLQRLLRILASYGVFTEHLSNSDDRKYSLTEIGKTLVNNSDGVSYAPYVLQHHQISLNIHRLRVQDELIRSWPLLHEAITDPTTEPFAKANGEPAYSFYGKKPEMNELMQKAMSGTSVPFMNAMLAEYDGFNGVERIVDVGGSGGDCLRMILHRHPDIKEGINFDLPEVVAKAPIIPRVTHVGGDMFRSIPKADAIFMKWILSTWTDDECTSLLENCHRALPAGGKLIACEPVVPRESDSSMRTRALLENDVFVMAIYRAKGKNRTRQEFEKLGRSAGFPTFRVLEIDYFYTVMEFQK
>Begfu8797S42818
MGSAGETQTTPTQVSDEEANLFAMQLASASVLPMVLKAAIELNLLEIVARAGPGALLSPSEIAEQLPTTNPDAAVMLDRMLRLLASYSVLTYSLRTLPDGRVERLYGLAPVCKFLIRNEDAVSIAPLVLMNQDKVLMESWYHLKDAVLEGGIPFNRAYGMTAFDYHGTDPRFNKVFNRGMSDHSTITMKKILETYRGFEGVGSVVDVGGGTGAVISMILSKYPSIKGINFDLPHVIEDAPEYPGVEHVGGDMFVSVPKGDAIFMKWICHDWSDQHCLKLLKNCYEALPRKGKVIVAECILPVAPDSSLATKGVMHIDVIMLAHNPGGKERTQEEFQALAEGAGFQGFRVECCAFNTYVMEFLKSV
>Begfu91244S51206
MASPEIIPDDGEETFSYAVQLSMSSLLPMSLYAAVELGVFEIIANAGPNAGLSSADIAAKLATQNPQSASMLDRILCLLASHSVLHCSQATDANGHLRRVYSLAPVAKFFVRDEDGVALGPFQALVQSKLFLESWSEMKSAVLEGGIPFNKVHGCYSYEYPAKDEHFNEIFNSAMFNYTTIVTKKVLQTYNGFGGIGKLVDVGGGLGTTLSMITSKYPSIKGVNFDLPHVIARAPEYPGVEHVGGDMFESVPRGDAIFLKWILHNWSDEHCLKVLKNCFAALPDAGNVIVVEAIVPNMPETTAACRSMCAMDVQMMTQFSGGKERSREEFTALAIGAGFNGVRFRCFVSNFWIMEFFK
>Begfu91231S43318
MLHSHINTKYLLMTLDSVALSPWQELSKWFHSDYLTAFEMLSGRNFYGHFPDNPEFAKLFNEAMMWDSKMISIALVGECKEVFEGLKSLVDVAGGSGAMMEAIAEAFPHIHCTVLDLPHAIAEKKGRKNMEFVSGDMFEAIPSANAVLLKWVIHNWDDEKSIEILKNCKKAIPSKEEGGKVIIIDMRFDEVTTLDSKIVSIALVEECEEVFEGLKSLANVAGGSRARMEALAEAFPHFHCTLLDLPHAIAEKKGSKNLEF
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University