Enzyme

4CL

Enzyme

4-coumarate:CoA ligase

Enzyme name

EC:6.2.1.12

Entry

Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases

Class

4-coumarate:CoA ligase (AMP-forming)

Sysname

ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]

Reaction

AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]

Product

Species information

Begonia fuchsioides

Species name

Begonia fuchsioides is a species of eudicot in the family Begoniaceae (begonia family).

Species info

Gene sequence info

Begonia_fuchsioides.4CL.fa

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>Begfu449S04456
MDVAVILYSSGTTELQLGNAKVLMSEFDLEKYKVTDMWVEPPIVLALAKQGDGDLGYFDESGRLFVVDRIKELIKFKGFQIAPAELEGLLVSHPEILDSVVIPFPDAEAGKIPIAYVVRSPDSSLTEKAMIEFI
>Begfu323S31075
MAALFNPESYIYSSPRPPIVFPADPNLSITSFLFQRTSSFPHRIALVDAVNGGSFTFHQLKIHVSKLSRALLRLGIEKGSVVLIFSPNSLYFAVSFSAIVAIGAIATTCNPSYTVPELLNQVNDCNPKLVITVPELWEKVCPLNLPSIFLESPISSGFPMNRIPSVRFYSDLVAKSSESSEIPDANTVQDDIAAFLYSSGTTGTSKGVVLTHRNFIATALIATGDQDDQGDGMNVALCFLPMFHVYGLAILLYAQLARGNRVVSMAKFELETAMKAVEKHRITHLYAVPPVMIALAKGSTVNKYDSSSLLQISSGGAPLSSDVIVAVKKNFPNAKVLQGYGMTETCAVISKAFPTERSSLSSSTGPLSSGIEAKIIDVETFKPLPPHCLGEIYVRGPSIMRGYLNNVEATKLTIDDQGWLHTGDLGYFNNAGELFIVDRIKELIKCYGFQVAPAELEGILLSHPDIIDAVVIPRVDVKAGEVPVALVVKSASSSITAEDVKKLVANQVAPFKRLRSITFVNSIPKSASGKILRREVIQMVRARM
>Begfu724S40367
MGTHLQALAEEEDDQHIFRSNFPAVQVPENITLPQYVLEDAESYANKVALVEALTGKEITYGEVVRDTKRLSKALRSLGLRKGQVVIVLLPNIAEYPIVVLGIMSSGGVFSGANPSAHSSEIRKQVEVAEAKLIITNGSNYEKVKGFDLPVIVLGEEPIEGAMNWDKLLEAADRAGTELNSVETVKQTDLCALPFSSGTTGVSKGVMLTHGNLVANLCSTLFNVPEEMVGQVTTLGLIPLFHIYGITGICCATLRNKGKVVVMGRFELRMFLNALITQEVTFAPIVPPIILALVKNPIVEEFDLTKLKLQAIMTAAAPLAPEILSAFEKKFSGVDVQEAYGLTEHSCITLNYGVIERNNGRMKKNTVGQILPNLLVKFIDPETGKSLPKNTHGEICVKSQCVMKGYFRNEEETRRTIKNGWLHTGDIGYIDDDGDVFIVDRIKELIKYKGFQVAPAELEAILLTHPSIEDAAVVPLPDEDAGEIPAASVVLGGNATESEEDIIRFVASNVAHYKKIREVQFVDSIPKSPSGKIMRRLIKASMLEKMKPKAQPNIGR
>Begfu723S50641
MAAETKPGDFIFRSKLPDIPIPKHLPLHAYCFENIAEFGSRTCLINGATGEKYTYDEVRRTSIKVAAGLSKLGFGKGDVVMLLVPNSPEFAFVFLAASFLGAITTAANPFFTPAEIGKQAKASKAKLIVTQASFYPKIKDLAQESEPNSVKIICTDSAVDGCLQLSSLINDGDETALPDVKINPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVSQQVDGENPNLYYRKDDVILCVLPLFHIYALNSVFLCSLRVGAAVLLVQKYEIVSFLQMIEKYRVSSVPVVPPIVLATARSPEVDKYDLSSIRVLKSGGAPLGKEIEDSIKCRLPMAVFGQGYGMTEAGPVLTMSLGFAKRPWKVKAGGCGTVVRNAEMKIVDTETGASLPRNSRGEIFIRGDQIMKGYLDDPEATARTIDGEGWLHTGDIGFIDDDDELFIVDRLKELIKFRAFQVAPAELEAILLTHPSISDAAVVPFEFVNEHETTARMKDDQAGEVPVAFVVSPENSQITEDEVKQFISKQVVFYKRLNRVFFIDAVPKSPSGKILRKELRAKLENGRF
>Begfu800S50851
MITVASSIEAQQPELSPTAVKTAGPDLLTKADCETKHIFKSKLPDIPISNHLPLPTYCFERLSEFSDRPCLIVGSTGKTYTFAETHLISQRIGAGLTKLGVKKNDVIMILLQNCAEFVLTFVGAAMIGAVTTTANPFYTGAEVFKQIKSSGAKLIVTQSQYVEKLRAMADEDPKIGEDFTVITIDSPPENCLHFSSISEANEADLPAVTIEPEDAVALPFSSGTTGLPKGVILTHKSLITSVAQQVDGENPNLYLTTDDVVLCVLPLFHIYSLNSVLLCSLRAGAAVLLMQKFEIGAFLELIVRHKVSVAAVVPPLVLALAKNPKVADYDLSSIRVVLSGAAPLGKELEEALQSRLPQATLGQGYGMTEAGPVLSMCLGFARQPFPIKSGSCGTVVRNAELKVIDPLTGASLGYNQPGEICIRGSQIMKANVFDFECHTKLGYLNNDEATANTIDVEGWLHTGDIGYVDDDDEVFIVDRVKELIKFKGFQVPPAELESLLVNHPQIADAAVVPQKDAVAGEVPVAFVVRSNGFELTEDAVKDYIAKQVVFYKKLHRVYFVHAIPKSPAGKILRKDLRAKLSSPSSC
>Begfu817S41677
MKSFDAGEMVKAIERERVTHLTVVPPILRSLTNAAKHSNGSFKSLKQVCCGAAPVSKTEIDEFVRLLPHVDFIQGYGMTESTEVATRGLNTNKFKHYCSAGLLATSMEAKIAPADLEAILISHPKFYSVFSLPFELFCSMKDEECGEIPVAVVVVKPGAMLSSQDVMNYVAKQVAPYKKVR
>Begfu878S42801
MAAGPEVNEFIFRSKLPDIHIPNDLPLHAFCFEKIAEVGSRPCLIDGSTGDIFTYDDVRLTARKVGAGLKSLGVGKGQVIMLLLPNCPEFVFSFLGASYGGAIMTAANPFFTEAEIAKQAKASKAKVIITQACHYEKVKDLPGVNIICTDAPPEGCLHFSDLTKSEEENTPAVEICPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVSQQVDGDNPNLYYGRDDVVLCVLPLFHIYSLNSVLLCSLRSGAAILIMPKFEIKLLLNLIQKYKVSFAPIVPPIVLAIAKSPELESYDLSSIRVLKSGGAPLGKELEDTVRAKFPKAVLGQGYGMTEAGPVLTMSLAFAKYPSPVKPGACGTVVRNAELKVLDIETGASLPRNARGEICIRGGQIMKGYLNDPEATDRTIDKQGWLHTGDIGFVDEDDELFIVDRLKELIKYKGFQVAPAEIEAILLTHPRVSDAAVVPMKDEQAGEVPVAFVVKAKNCEPTEDEVKQFISKQVVFYKRLNRVFFIDAIPKAPSGKILRKNLKAILADGPPN
>Begfu850S42396
METQKSGDFPDWYSPETGIYRSKFPDVDLPSDPFLDVVSFVFSDQHNGRVALIDSSSGYCLSYSDLHSLVKSMAAGLHNAGVSQGDVVLILLPNSILYPIILMGVLYLGVIVTTMNPRSNISEIKKQCAECNVCFAFAECESVSKLQALGFPVVGVPDNVDLGSKPVQFSPFHQFISCSPDLKKKPVINQQDTAAILFSSGTTGASKGVVLTHRNFIAMVELFVRFEASQYKYPCWNNVVLAIMPMFHIYGFCHFCLGLLSLGCSIVVMKSFDADEMVKAIERERVTHLTVVPPILRSLTNAAKHSNGSFKSLKQVCCGAAPLSKAEIDEFVCHFPHVDFIQGYGMTESTAVATRGLNTKKFKNHCSAGLLAPSMEAKVVDYQRGSSLPPGDCGELCLRGPAVMKGYLNNAEATLLTIDSDGWLHTGDIVYFDSDGYLYIVDRVKEMIKYKGFQIAPADLEAVLLSHPKILDVAVIGMKDEECGEIPVAAVVVKPGAELSHQDVINYVAKQVAPYKKVRKVVFAKSIPKSAAGKILRRELKNQIPSKL
>Begfu850S42481
MGSLPNHHEFIFRSKLPDIYIPNHLPLHSYCFQNISEFEDRPCLINGATGETFSYSAVELSSRKVAAGLSKLGIGKGDVIMLMLQNSVEFVFAFLGASQLGAISTTANPFYTPAEVTKQAKSAAVKLIITQSAYVEKVRDFAEQNDVKLMCIDSPPDGVLHFSELSQADERDIPAVKINADDVVALPYSSGTTGLPKGVMLTHRGLVTSVAQQNVILCTQVDGENPNLYFHKNDVILCTLPMFHIYSLNSVLLCALRVGAAILVVQKYDIKGLLELVQKYKVTIAPLVPPIVLDIAKSAEIDNYDLSSIRIVMSGAAPMGKELEDTVSAKLPNAKLGQGYGMTEAGPVLSMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPETGLSLPKNQSGEICIRGSQIMKGYLNDEEATKRTIDGDGWLHTGDVGYIDDDDEVFIVDRLKELIKYKGFQVAPAELEALLAAHPKISAAAVVSMKDETAGEIPVAFVVRSNGWKISEDEIKKYVSDQVVFYKRIRRVFFVESIPMAPSGKILRKNLRARLAEMEA
>Begfu1568S20889
MEKSGYGHDGVYRSIRPGLSLPQAPDLSMVTFLFRNSSSYLHKPALIDADSSETLSFAQLKSMVIEVSHGLLHLGIKKSDVVLIFAPNSIQFPICFLAIIAIGAVATTCNPTYTVSELMKQAKDSKPKLVITVAELWDKAVNLNLPTVLLGPKGSSTPPENSTVSTFDDLVRLGRSENHFPAVKVKQTDTAVILYSSGTTGTSKGVILSHRNFIAASLMITQDQQMAGEMHNVYLNVLPLFHVFGLSCVTFAQLQIGNSMVLMSKFDLEKFLSAVEKYKVTDIWVVPPIVLALAKQKVVKNYDLSSLRHIGSGAAPLGKDLMDECVKNLPGARVIQGYGMTETCGIISIENPRVGVRNTGTAGNIVGGVEAQIISVDTLKPLPPNQTGEIWVRGPNMMHGYFNNPEATNQTIDQNGWVHSGDLGYFDENGRLFVVDRIKELIKFKGFQIAPAELEGLLVSHPEILDSVVIPFPDAEAGEVPIAYVVRSPNSSLTEKDIIEFISKQVAPFKRLRRVTFVNSVPKSVSGKILRRELIEKVRSKI
>Begfu1692S08622
MGSQPNHHEFIFRSKLPDIYIPNHLPLHSYCFENISEFEDRPCLINGVTGETFTYAAVELTSRKVAAGLCKAGIGKGDVIMLMLQNSAEFVFAFLGASHLGAISTTANPFYTPAEVTKQAKSAAVKLIITQSAYVEKVRDFARENDVKLMCIDSPADGVSHFSELTQADERDIPAVKINPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLCFHKNDVILCTLPMFHIYSLNSVLLCALRVGAAILIVQKYDIKGLLELVEKYKVTIAPLAPPIVLDIAKSAEIDDYDLSSIRIVMSGAAPMGKELEDTVSAKLPNAKLGQGYGMTEAGPVLSMCLAFAKVPFEIKSGACGTVVRNAEMKIIDPETGLSLPKNQSGEICIRGSQIMKGYLNDEAATKRTIDGDGWLHTGDVGYVDDDDEVFIVDRLKELIKYKGFQVAPAELEALLAAHPKISAAAVVSMKDESAGEIPVAFVVKSNGWKISEDDIKNYISDQVVFYKRIRRVFFVESIPVAPSGKILRKNLRARLAEMEA
>Begfu1756S22461
MDSTPEKKEHIFRSKLPDIYIPSHLNLHTYCFEHVSKFQDRPCLIDGLSDKVYTYADVHSTTRRTAAGLCKLGIKKGDVILLLLQNSPQFVYAFIGGSYLGAAITTANPFFTAGEIIKQATAANVKLIVTQAAFVDKVKDFSDENNVKIVVTDSSAAGFVKFSDLTSADETDIPEVIIDPDDTVALPFSSGTTGLPKGVMLTHKCMVTGVAQQVDGENPSLNFTSSDVILCVLPIFHIYCLSSIMLSGLRVGAAILIMPRFEINRLFELVDKYKVTVAPFVPPIILAIAKNDNAGNYDLSSVKLVMSGAAPMGKELEDVVRSKLPNAKLGQGYGMTESASAITLSLAFAKHPMEVKPGACGTVIRNAEMKIVDPETGDSLPRNHAGEICIRGNQIMKGYLNDKKATEKTIDEEGWLHTGDVGYVDDDGEVFIVDRLKEMIKYKGFQVAPAELEALLVAHPHISDGAVVSMQDEVTGEVPVAFVVRSNGSNVSENEIKNYISNEVVFYKRINRVFFVDSIPKSPAGKILRKDLRACLAVLPKN
>Begfu2009S24162
MAADGEVNEFIFRSKLPDIHISNDLPLHAFCFEKIAEVGSRPCLINGSTGDIFTYDDVRLTARKVAAGLKTLGVGKGEVIMLLLPNCPEFVFSFLGASYGGAIMTAANPFFTEAEIAKQAKASKAKVIITQACHYDKVKDLAGVNIICTDAPPEGSLHFSDLTKSDEENTPAVEIYPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVSQQVDGDNPNLYYGRDDVVLCVLPLFHIYSLNSVLLCALRSGAAILIMQKFEIKLLLNLIQKYKVSVAPIVPPIVLAIAKSPELENYDLSSIRVLKSGGAPLGKELEDTVRAKFPKAVLGQGYGMTEAGPVLTMSLAFAKYPSPVKPGACGTVIRNAELKVLDIETGASLPRNARGEICIRGDQIMKGYLNDPEATDRTIDKYGWLHTGDIGFVDDDDELFIVDRLKELIKYKGFQVAPAEIEAILLSHPRVSDAAVVPMKDEQAGEVPVAFVVKAKNCQLTEDEVKQFISKQVVFYKRLNRVFFIDAIPKAPSGKILRKNLKAILANGPPN
>Begfu2258S25504
MGTYLQVPAQEDDDQHVFHSNFPTVQVPENITLPQFVLEDAELYANKVALVEALTGKEITYGEVVRDTKRLSKALRSLGLRKGQVFIVLLPNIAEYPIIVLGIMSSGGVFSGANPSSHSSEIKKQVDVADAKLIITNGSNYEKVKGLDIPIIVLGEEPIEGAMNLAKLLEAADRAGTETNSIESVQQNDLCALPFSSGTTGVSKGVMLTHRNLVANLSSTLFNVPKEMVGQVTTLGLIPLFHIYGITGICCATLRNKGKVVVMGRFELRMFLNALITQEVTFAPIDPPIILALVKNPIVEEFDLTKLKLQAIMTAAAPLAPEILSAFEKKFPGVDVQEAYGLTEHSCITLNYGVIERENGKMKKNTVGQILPNLLVKFIDPETGKSLPKNSHGEICVKSQCVMKGYFRNEEETRRTIKNGWLHTGDIGYIDDDGDVFIVDRIKELIKYKGFQVAPAELEAILLTHPSIEDAAVVPLPDEVAGEIPAASVVLGGAEMRRRAKKI
>Begfu2529S27312
MDSTPEKKEHIFRSKLPDIYIPSHLNLHTYCFEHVSKFQDRPCLIDGLSDKVYTYADVHSTTRRTAAGLCKLGIKKGDVILLLLQNSPQFVYAFIGGSYLGAAITTANPFFTAGEIIKQATAANVKLIVTQAAFVDKVKDFSDENNVKIVVTDSSAAGFVKFSDLTSADETDIPEVIIDPDDTVALPFSSGTTGLPKGVMLTHKCMVTGVAQQVDGENPSLNFTSSDVILCVLPIFHIYCLSSIMLSGLRVGAAILIMPRFEINRLFELVDKYKVTVAPFVPPIILAIAKNDNAGNYDLSSVKLVMSGAAPMGKELEDVVRSKLPNAKLGQGYGMTESASAITLSLAFAKHPMEVKPGACGTVIRNAEMKIVDPETGDSLPRNHAGEICIRGNQIMKGYLNDKKATEKTIDEEGWLHTGDVGYVDDDGEVFIVDRLKEMIKYKGFQVAPAELEALLVAHPHISDGAVVSMQDEVTGEVPVAFVVRSNGSNVSENEIKNYISNEVVFYKRINRVFFVDSIPKSPAGKILRKDLRACLAVLPKN
>Begfu3813S33012
MEKSGYGRDGVFRSLRPRLKLFLFLAQNSPHRRDSSETLSFSQLKYMVVKVSHGFLHLGINKNDVVLIFAPNSIQFPICFLGIIAIGAIETTCNPMYTLSELKKQV
>Begfu4391S12202
MDPTPEKDEHIFRSKLPDIYIPSHLNLHTYCFEHVSKFQDRPCLIDGVSDKVYTYAEVYSTARRTAAGLSKLGIKKGDVIMMLLQNSPQFVYAFLAGSYLGAAITTANPFFTPGEIIKQATGANVKLIVTQAAFVDKVKDFSDQNSVKIVVTDSSAAGFVNFSDLTSGEETGIPDVVINPNDTVALPFSSGTTGLPKGVMLTHKCMVTGVAQQVDGENPSLNFSSSDVLLCVLPLFHIYCLSSIMLSGLRVGAAILIMQRFEINRLFELVEKYKVTVAPFVPPIILAIAKNDHTCNYDLSSIKLVMSGAAPLGKELEDAVSSKLPKAKLGQGYGMTESASAISLSLAFAKRPSEVKPGACGTVIRNAEMKIVDPETGASLPRNHAGEICIRGDQIMKGYLNDKKATDSTIDKEQWLHTGDVGYVDDDDEVFIVDRLKEMIKYKGFQVAPAELEAMLIAHPQISDAAVVSMQDEAAGEVPVAFVVRSNGSNISEDEIKEYISNQVVFYKRTKRVFFVDSIPKSPAGKILRKDLRARLAVLPKN
>Begfu4478S35325
MEKSGYGRDGVFRSLRPRLVLPQDPDLSMISFLFRNSSSYSHKPALIDADSSETLSFSQLKSMVIKVSYGFLHLGIKKNDVVLIFAPNSIQFPICFLGIIAIGAIATTCNPMYTLSELRKQVGDSKPKLVITVAELWDKVMSFNLPTVLLGSEGSFPSISSNSKIITFHDLVQLGRLESHFPAVKIKQTDTAVLLYSSGTTGTSKGVILSHRNFISASQMIVSDQIMAGEMHNVYLNVLPLFHVFGLCCITFSQLQKGNCVVIMPKFEFQKLLSAIEKFKVTDLWIVPPIVLALAKQSLVKKYDLSSLRHIGSGAAPLGKDLMEECVKNIPTAQIIQGYGMTETCGIVALENPDVGIRNTGAAGTLVGGVEAQIIDVDTLKSLPPNQMGEIWVRGPNMMQGYFNNPQATRQTIDRNGWVHTGDLGYFDDDGRLFVVDRIKELIKYKGFQIAPAELEGLLVSHPEILDSVVIPFPDAEAGEVPIAYVVRSPNSSLTEEDIMEFIAKQVAPFKRLRRVTFVNSVPKSASGKILRRELIERARSKI
>Begfu6326S50444
MASEKQRNEFIFRSKLPKISVPNHLPLHAYCFENIAEVGPRPCLINAATGDSYTYDEVRSSAIKIAAALAKLGFGKGDVVMNLLPNSPEFAFVFLAASFLGAIMTAANPFFTPAEIEKQVKASKAKIIVTQAVFYTKVRHLVQDSEPNNVTIICTDTPVDGCLRLSSLIDDGEESPVIPDVKISPDDVVALPYSSGTTGLPKGVMLTHKSLVTSISQQVDGENPNLYYHKNDVVLCVLPLFHIYSLNSVFLCALRRGASVLIMHKYEILSLLQLIEKYKVSIVPVVPPIVLAIARSPELDKYDLSSIRVLKSGGAPLGKELEDCVKAKFPKAVFGQGYGMTEAGPVLTMSLGFAKQPFKVKSGGCGTVVRNAEMKIVDVETGASLPRTSSGEICIRGDQIMKGYLNDQEATARTIDGEGWLHTGDIGFLDEDDELYIVDRLKELIKFRAFQVAPAELEAILLTHPSVADAAVVPYVIEPHSSNSFYTTINMKDDQAGEVPVAFVVSPEKSEITEDEIKQFLSKQVVFYKRLNRVFFTDAIPKSPSGKILRKELRAKLVTGVPI
>Begfu6026S38571
MISVASSIEAQQPELSPTAVKPKSPNIFRPVESETDVIFRSKLPEIPIPNHLPLPTYCFERLPEFSDRPCLIVGATGKTYTFGEAHLISKRVGAGLTNLGVKKNDVIMILLQNSAEFVFTFIGAAMIGAVATTANPFYTGAEVFKQIKSSGAKLIVTQSQYVEKLREPTENDPKLGEDFTVITIDNPPEKCIHFSVLSEADDASLPATAISANDAVALPFSSGTTGLPKGVILTHKSLITSVSQQVDGENPNLYLTPDDVVLCVLPLFHIYSLNSVLLCSLRAGAAVLLMQKFEIGAFLELIVRHKVSVAAVVPPLVLALAKNPKVAEFDLSSIRVVLSGAAPLGKELEEALKSRLPQATLGQGYGMTEAGPVLSMCLGFARQPFPTKSGSCGTVVRNAELKVIDPNTGASLGYNQPGEICIRGSQIMKGYLNDDEATKNTIDVDGWLHTGDIGYVDDDEEVFIVDRVKELIKFKGFQVPPAELEALLVSHPAIADAAVVPQKDVVAGEVPVAFVVRSNGSDLTEEDVKEFIAKQVVFYKKLHRVYFVGAIPKSPAGKILRKDLRAKLASS
>Begfu91337S14531
MITVASSIEAQQPELSPAAVKTAAPDRLSKADCETEHIFKSKLPDIPIANHLPLPTYCFERLPEFSDRPCLIVGSTGKTYTFAETHLISQRIGAGLTKLGVKKNDVIMILLQNCAEFVMTFVGAAMIGAVTTTANPFYTGAEVFKQIKSSGAKLIVTQSQYVEKLRGTAEDYPKIGEDFTVITIDSPPEKCLDFSLISEANEADLPAVAIDPEDPVALPFSSGTTGLPKGVILTHKSLITSVAQQVDGENPNLYLTTDDVVLCVLPLFHIYSLNSVLLCSLRAGAAVLLMQKFEIGAFLELIVRHKVSVAAVVPPLVLALAKNPKVAEYDLSSIRVVLSGAAPLGKELEEALQSRLPQATLGQGYGMTEAGPVLSMCLGFARQPFPIKSGSCGTVVRNAELKVIDPLTGASLGYNQPGEICIRGSQIMKGYLNDDEATANTIDVHGWLHTGDIGYVDDDEEVFIVDRVKELIKFKGFQVPPAELESLLVNHPQIADAAVVPQKDAVAGEVPVAFVVRSTGFELSEDAVKEYIAKQVVFYKKLHRVYFVHAIPKSPAGKILRKDLRAKLSPPSPLC

Gene tree

Gene tree

Sheng jun & Dong yang Teams, Yunnan agriculture University