Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Azolla filiculoides
Species name
Azolla filiculoides is a species of fern in the family Salviniaceae.
Species info
Gene sequence info
Azolla_filiculoides.COMT.fa
Download
>Azfi_s0019.g015237
MFIDIPQADAIFMEWILHDWSDGHCMKILENCYKAHPNNGKVIVIDGILRIGWFEEEWGKHS
>Azfi_s0019.g015238
MGLKTLIKLEVFKVMANVDTEKDATERGLYSTEEIVSRMHVSPNAKMSVSIALDRIFRVITSHGVVRAKNDHDTFNKHPTRKCGLNLPIFCQQVLLQTWQFLHKAILDGGQPFKKAHNGLDAFEYGQLNPHFDSIFNSAMAIHSALLIGALLNSYPTYFNDINVLVDVGGGLGSSLHMILSHFPHIRGINFDQPHVIYLAPKYSGRQLWQAYLMYDIMNFKFGEEFVISNVHIFHFTIYTSPWL
>Azfi_s0019.g015239
MGEVVEESMHEMKCEGGVVDQAWLRAFELASLCCLPMGLKTLIKLEVFDVMANADIEKDATERGFYSTEEIVSRMNVSPDAKMRVSIALDRILRVVASHGVIHAKIDHDTFNKHPTRKYGLNLVSQYFVNKEHSLAPMVLMNQDSVFMETWHFLHEAILDGGQPFKKAHNGLEAFEYGQLNPRFDSIFNSAMASHSALLIGALLNSYPTCFHDINVLVDVGGGLGSSLHTIVSHFPHIRGINFDQPHVISLAPKYSGIEHVAGDMFIDIPQADAIFMKWILHDWSDGHCLKILENCYKALPNNGKVIIIDATLPTGIESDLRARVGYHLDLLMFAYNPGGRERTQEDMEYLAKVAGFARLEVKCKLNECSVIELYKLLGVNSSEASVSDDGDRPQSHHHECSEPSKYEERSSFSLDSALPYGRDDELRGPKMAALKLRFKQILNLKNPKHEHASKDGTKEYSAS
>Azfi_s0026.g023303
MGDIVNESMHRVMSEGGLEDQPWLRAVELSLLCCLPMAMSTLIQLKVFDVMAHADTEKGGTTERGLYSAEEIASRMSSVLPDARTRVSVALDRILRVVASHGVVHANVDRDPFTKHPTRRYGLNLVSQYFVQNESSLAPLLCLSVDPVTIKSWHVLHEAILDDGQPFSKAHNGLDLFEYGQLDPHFGSTFNFAMTSYCALPIRYLLESYPTCFDDVNILVDVGGGHGSSLHSIISHFPHIRGINFDQPHVISLAPHYSGIEHVAGDMFIEIPQADAIFMKMILHDWTDEHCMKILENCYKALLNNGKVIIIDAILPMGIERDLRARVGYHLDLQMFAQSIGGRERTHEELENLAKSVGFARLEVKSKLNEYSVIELYKF
>Azfi_s0026.g023313
MGDIVNESMHRVMSEGGLEDQPWLRAVELSLLCCLPMAMSTLIQLKVFDVMAHADTEKGGTTERGLYSAEEIASRMSSVLPDARTRVSVALDRILRVVASHGVVHANVDRDPFTKHPTRRYGLNLVSQYFVQNESSLAPLLCLSVDPVTIKSWHVLHEAILDDGQPFSKAHNGLDLFEYGQLDPHFGSTFNFAMTSYCALPIRYLLESYPTCFDDVNILVDVGGGHGSSLHSIISHFPHIRGINFDQPHVISLAPHYSGIEHVAGDMFIEIPQADAIFMKMILHDWTDEHCMKILENCYKALLNNGKVIIIDAILPMGIERDLRARVGYHLDLQIIGGRERTHEELENLAKSVGFARLEVKSKLNEYSVIELYKF
>Azfi_s0026.g023324
MLRAVELSLLCYLPMSINTLIKLKAFDFMANTDTEKCGTTEGGLCSAEEIVSRMSSSVLAYLAKTRVSIGLDRLLRVVASHGVVHGDIGHDAFTKHPTRKYGLNLVSQCFVHDDSCLAPLHLCAGPVTIKPWHFLHECVLDGGQPFAKAHDGLDLFAYGQTDPHFGSIFNSVMTNGSIVPICDLLDSYPTCFDDINILVDVGGGHGSSFHFIISRFPHIRGINFDQPHVISLAPNYSRIEHVVGDMFIEIPQVDAIFMKLILHDWSDEHCMKILENCYKALLNNGKVIIIDAILPMGFERDLRTHVGYQYDLYMFAQTNGGRERTQEELENLAKSVGFARLEVKSKLNEYSVIKLYKL
MFIDIPQADAIFMEWILHDWSDGHCMKILENCYKAHPNNGKVIVIDGILRIGWFEEEWGKHS
>Azfi_s0019.g015238
MGLKTLIKLEVFKVMANVDTEKDATERGLYSTEEIVSRMHVSPNAKMSVSIALDRIFRVITSHGVVRAKNDHDTFNKHPTRKCGLNLPIFCQQVLLQTWQFLHKAILDGGQPFKKAHNGLDAFEYGQLNPHFDSIFNSAMAIHSALLIGALLNSYPTYFNDINVLVDVGGGLGSSLHMILSHFPHIRGINFDQPHVIYLAPKYSGRQLWQAYLMYDIMNFKFGEEFVISNVHIFHFTIYTSPWL
>Azfi_s0019.g015239
MGEVVEESMHEMKCEGGVVDQAWLRAFELASLCCLPMGLKTLIKLEVFDVMANADIEKDATERGFYSTEEIVSRMNVSPDAKMRVSIALDRILRVVASHGVIHAKIDHDTFNKHPTRKYGLNLVSQYFVNKEHSLAPMVLMNQDSVFMETWHFLHEAILDGGQPFKKAHNGLEAFEYGQLNPRFDSIFNSAMASHSALLIGALLNSYPTCFHDINVLVDVGGGLGSSLHTIVSHFPHIRGINFDQPHVISLAPKYSGIEHVAGDMFIDIPQADAIFMKWILHDWSDGHCLKILENCYKALPNNGKVIIIDATLPTGIESDLRARVGYHLDLLMFAYNPGGRERTQEDMEYLAKVAGFARLEVKCKLNECSVIELYKLLGVNSSEASVSDDGDRPQSHHHECSEPSKYEERSSFSLDSALPYGRDDELRGPKMAALKLRFKQILNLKNPKHEHASKDGTKEYSAS
>Azfi_s0026.g023303
MGDIVNESMHRVMSEGGLEDQPWLRAVELSLLCCLPMAMSTLIQLKVFDVMAHADTEKGGTTERGLYSAEEIASRMSSVLPDARTRVSVALDRILRVVASHGVVHANVDRDPFTKHPTRRYGLNLVSQYFVQNESSLAPLLCLSVDPVTIKSWHVLHEAILDDGQPFSKAHNGLDLFEYGQLDPHFGSTFNFAMTSYCALPIRYLLESYPTCFDDVNILVDVGGGHGSSLHSIISHFPHIRGINFDQPHVISLAPHYSGIEHVAGDMFIEIPQADAIFMKMILHDWTDEHCMKILENCYKALLNNGKVIIIDAILPMGIERDLRARVGYHLDLQMFAQSIGGRERTHEELENLAKSVGFARLEVKSKLNEYSVIELYKF
>Azfi_s0026.g023313
MGDIVNESMHRVMSEGGLEDQPWLRAVELSLLCCLPMAMSTLIQLKVFDVMAHADTEKGGTTERGLYSAEEIASRMSSVLPDARTRVSVALDRILRVVASHGVVHANVDRDPFTKHPTRRYGLNLVSQYFVQNESSLAPLLCLSVDPVTIKSWHVLHEAILDDGQPFSKAHNGLDLFEYGQLDPHFGSTFNFAMTSYCALPIRYLLESYPTCFDDVNILVDVGGGHGSSLHSIISHFPHIRGINFDQPHVISLAPHYSGIEHVAGDMFIEIPQADAIFMKMILHDWTDEHCMKILENCYKALLNNGKVIIIDAILPMGIERDLRARVGYHLDLQIIGGRERTHEELENLAKSVGFARLEVKSKLNEYSVIELYKF
>Azfi_s0026.g023324
MLRAVELSLLCYLPMSINTLIKLKAFDFMANTDTEKCGTTEGGLCSAEEIVSRMSSSVLAYLAKTRVSIGLDRLLRVVASHGVVHGDIGHDAFTKHPTRKYGLNLVSQCFVHDDSCLAPLHLCAGPVTIKPWHFLHECVLDGGQPFAKAHDGLDLFAYGQTDPHFGSIFNSVMTNGSIVPICDLLDSYPTCFDDINILVDVGGGHGSSFHFIISRFPHIRGINFDQPHVISLAPNYSRIEHVVGDMFIEIPQVDAIFMKLILHDWSDEHCMKILENCYKALLNNGKVIIIDAILPMGFERDLRTHVGYQYDLYMFAQTNGGRERTQEELENLAKSVGFARLEVKSKLNEYSVIKLYKL
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University