Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Azolla filiculoides
Species name
Azolla filiculoides is a species of fern in the family Salviniaceae.
Species info
Gene sequence info
Azolla_filiculoides.4CL.fa
Download
>Azfi_s0003.g007625
MAPSESKHEVTSNLAPDSMSPPPVYLFKSKLPTIEIPDHLTLPEYCLQHSSKLGSKPCLIEMGQSGQATSQNHVTTFGDVIKKARCVATGLEPIAGIKKGDVVMLMIPNSSEFVISFLGAAMRGAIVTTCNPFYKSQEIEKQLSASKAKLIITQLGHIHKLTHIHVPHTFQVMVIDHEPLDIHQGQDQQNHHHLAQDHAPLDPPQFGPILSFSSFFDYSDDYQHDNFELDNCLKTSVFDDVHPDDVAALPYSSGTTGLPKGVMLTHRNLVTSISQQVDGDNPNMYFTPDDIVLCVLPMFHIYSLSIVLCCLRVGATMAIMPKFEIEALLEVVQRHRVTVAPLVPPIVLALAKNPLVQRYDLSSIRMLMCGAAPLSKDLQDSFKARVPHAIVAQGYGMTEAGSVLSMSLAFAKYPSPVKSGSCGTVLRNTVVKLIDPETGLSVPHNQPGEICIKGNQIMKGKFQTDCYLNDSVATSNTIDEDGFLHTGDIGIIDDDDELFIVDRVKEIIKFKGFQVPPAELEGILISHPSVTDAACVPKKDEAAGEVPVAFVVLTKGSEVTENELKQFVANQVIFYKKLHTIIFVDHIPKSPSGKILRKELRKRIEEEHIF
>Azfi_s0013.g013344
MESVAKHGDYDDGGGGEYIFRSKLPDIVIPNHLPLTSYCFEHMEQFSEKPCLVQSDGEKMYTYRDVELYSRRICAGFSKLHISKGDVVMLLLPNCVEFVLLFLGLARAGAASTTCNPFYTSQEITKQVIGSKAKMIITQAAYVEKLAEVAHSVLHSFQVMTIDDEIVAGHLHISSVMHANECECPHVDIHPDDLVALPYSSGTTGLPKGVMLTHKSLVTSIAQQVDGDNPNIHMTPNDVILCVLPMFHIYSLNTVLLCSLRVGATIAVMTKFEISGLLDTVQRYKVTIAPLVPPIVLALAKNPIVEKYDLSSIRMLMSGAAPLGKDLEAAFHSRVPQAIIGQGYGMTEAGPVLAMCLAFAKHPFPVKPGACGTVVRNADVKIIDPETGASLPRNMPGEICIRGDQIMKGYVGDTQATTSTIDEHGFLHTGDIGLIDDDDEVFIVDRVKEIIKFKGFQVPPAELEAILLSHPSILDAACVPIPKSPSGKILRKELRSRLEETTAN
>Azfi_s0027.g023677
WQTERMTTLQGEEEEEIIFKSQLPPSPIPSDLSLPQFVFQNIDEYPDAIAIVDASDGRSFTYDQVRSLSFKVAVGLYLNFNIRRGDVVCVILPNIPEYPFIVFGILTSGGVFTGGNTSSHSDELTKQITHSEAKLIITDAISYQKVQHLVAQIPIIIVGPHDPLEGVTPIEKLYETDTTNVCLPQVLQEDLCALPFSSGTTGVSKGVMITHRNLIANLCSTLFDLERANLTPGQNVTLGLMPFFHIYGFTGICCSTLRSKGTVVVMARFELRLFLNALIDYGVTFAPIVPPIILALVKNPLVNEFDLTKLKLLAVMTAAAPLAPDLQKSFEEKFPGVIIQEAYGLTEHSCITLSHCAPDHVRGNSKKGSVGFILPNLEVKFIDPETGKSLPQNKLGELCVRSQCVTIGYFKNDEATKSTIDEKGWLHTGDVGYIDDDGDIFIVDRIKELIKIPNEEAGEIPVACVVLANGSSLKEDDIIHFVASKVASYKKVRMVFFFDSIPKNASGKILRRNARDTVLKRLQDSTNNN
>Azfi_s0030.g024259
MLLLPNCAEFVFLFLGVAMAGSVVTTANPLYKPAEIHRQVQSCQAKLIVTQAVYVEKLAEECERHIRIMTIDEEKEGHDHVSVLFEEKEGPKNPSVGDEDEADKKSGIRPIEPDDVVALPYSSGTTGLPKGVMLTHRSLLTSVAQQVDGENPNLHFSPDDVVLCVLPLLHIFSLNSVLLCSLRAGSAVAIMQRFEVVALLEFVQRYRISVLAVVPPIVLAITKCPTKHLYDLSSVRKVLSGRRPHGERARGRAPRMLAQCRDRPVSSFLLARSKFIDIGYGMTEAGPVLSMCMSFAKNPSPVKPGSAGTVVRNAEMKVVDTETGKSVSYNQPGEICIRGKQIMKGYLNNPEATTYTIDKDGWLHTGDVGFVDDDDEVFIVDRVKEIIKYKGFQVPPAELEGMLLAHPSIHDAAVIPEPDDAVGEMPVAFVVRSNGSDISEDEIKRYIAAQVVFYKRICKVYFVETIPKSPTGKILRRELRKKLADEIALRKSQSA
>Azfi_s0114.g046013
MSGQVVMSPTPISSLNHTTPPANSHQITAPSVPQQPPSSPKHEHIFRSPLPDIDIPTNLSLPDYIFENASRYPHKPCLIDHSSGRTYTYADVQLLSRRVASGLSRLGISRGHVIMLLLPNCPEFVFLFLGAAMRGAVATTANPLYKPDEIHRQARSSHARLIATQAAYAGKLAQECDPHIRILTVDEALDGVTHISSLLECDAATAFVRDMHYEDDRHFSPDDIVALPYSSGTTGLPKGVMLTHRSLITSLAQQVDGENPNIHYTPDDVVLCVLPLIHIFSLNSVLLCALRAGASVAIMQRFEIVNLLEIIQRHRITMVAVVPPIVLAIAKCPVVDRFDLSSVKKVLSGAAPMGKELEDAFRARLPNAIIGQGYGMTEAGPVISMCLSFAKHPTPVKPASCGTVVRNAEMKIVDTESGASLTYNQPGEICIRGKQIMKGYFNNPDATKFTIDKDGWLHSGDVGYVDDDGEVFIVDRVKEIIKYNGYQVPPAELEAMLIVHLEIRDAAVVSEPDEDVGELPVAFVVRSNGSNISEEEIKKYIAKKVVFYKRIRKVYFVDAIPKSPTGKILRRELRKKLVEDALALRRSTTSHT
>Azfi_s0258.g060636
PNSLSFTASCAAMVNSDGAAAGFDPKTFIFRSPRGELTIPPDLTIPSFLFQTTSARAYHHRVAIADASSHLSLTFSQLRLRIGSAARALSYAGISQGDVVLLLSPNTVHFPVLFFAIVSLGAVATTANPAYTPGEIAKQARDSHAKLILVHTDLLPKISGMNLPTIVIDSDSDSDSGKRSPSHPAAMTYLSDAERVSAGHLPPPVRICQADTAVLLYSSGTTGASKAVALSHLNLIASAVQTNSDAARFSEMDLSFFVPIPFFHVYGLSVILFAQLQRGNTIVTTPRFDLVDMLKAIEEYHVTSLPLVPPIMLALAKHDVALKYDLSSVTEITSGAAPLGKETIEEVASRIKIPNVRQGYGMTETAGFISVFPLRAEAKNFATVGPLVAGMEAVVVDPASGERLPPNKQGELWVRGPNVMQGYLNNPEATAATLEKDGWLHTGDLVYIDDDGYIYIMDRLKELIKYKGLQVAPAELEALLLTHPEIKDVAVVPLPDEDAGEVPFAYVVRAKGSSLQERDVIEFVAPQVAPYKKVRKVSFIAAIPRSSSGKILRRSLNKALNHAPS
>Azfi_s0464.g072360
MVNSDGGGAAAATGFDPKAFIFRSPRGELTIPPDLTIPSFLFQTTSARAYHHRVAIADASSRLSLTFSQLRLRIGSAARALSYVGVSQGDVVLLLSPNSIHFPVLFFAIVSLGAVATTANPVYTPREIERQARDSRAKLILVHPDLLPKLSSGLNLPILVIDSDSGTGKRSSSHCPAVSYLSDAERLSAGHLPPPARIRQADTAVLLYSSGTTSASKAVALSHLNLIASAIQTNSDADRLSETDLSFFVAIPFFHAYGLSVILFAQLQRGNTIVTTPRFDLVDMLKAIEEYHVTSLPLVPPIMLALAKHDVALKYDLSSVTEITSAAAPLGKETIEEVASRFKIPNVRQGYGMTETAGFISVFPLRAEAKNFATVGPLVAGMEAVVVDPTSGERLPPNKQGELWVRGPNVMQGYLNNPEATAATLEKDGWLHTGDLVYIDDDGYIYIMDRLKELIKYKALQVAPAELEALLLTHPEIEDVAVVPLPDEDAGEVPFAYVVRAKGSSLQERDVIEFVAPQVAPYKKVRKVCFIDAIPRSSSGKILRRSLNKALSHAPS
>Azfi_s0464.g072362
MVNSAAAAGFDPKTFIFRSPRGELTIPPDLTIPSFLFQTTSARAYHHRIAIVDPSSNLSLTFSQLQLRIRSAARALSYAGISQGDVVLLLSPNSIHFPVLFFAIVWLGAVATTANPVYTPGEIARQARDSRAKLILVHPDLLPKLSGLNLPILVIDSDSSPGKSSPSHGPAVSYLSDAERLSAGHVPPPVHIRQADTAALLYSSGTTGVSKGVILSHLNFIASAIQINSDAARLGEKDLSFFVVIPFFHVYGLSVILFAQLQRGNTIVTMPRFDFVSMLKAIQDYHVTSLPLVPPIMLALAKHDVALKYDLSSVIEITSGAAPLGKETVEEVSKRFKIPDVRQGYGMTETAGIISIFPLRTEAKNFATVGPLVAGMEAVVVDPTSGERLPPNKQGELWVRGPNVMQGYLNNSEATASTLEKDGWLHTGDLVYIDDDGYIYIMDRLKELIKYKGLQVAPAELEALLLTHPEIEDAAVVPLPDEDAGEVPFAYVVRAKGSSLQERDVIEFVAPQVAPYKKVRKVSFIDAIPKSSSGKILRRELPRTPSSRL
>Azfi_s1020.g095355
MVNSGGFDPKTFIFRSPRGELTIPPDLTIPSFLFQTTSARAYHHRVAIADASSRLSLTFSQLRLRIGSAARALSYAGISQGDVVLLLSPNSIHFPVLFFAIVSLGAVATTANPAYTPREIERQARGSRAKLIVAHPGSLPKLSGLNIPTIVIDSDSGTTKTTTTTTTTTHHHHQHHHRHHHPDQRLLSDAERLSAAAGHSPPPVRIRQVDTAALLYSSGTTGPSKAVPLSHLNLIASAIQTNSDAARLGHHDLCFFAVTPFCHVYGLSFLLLAQLQRGNTIVTIPRFNFVDMLKAIQEYHVTSLSLVPPVMLALAKHDAALRYDLSSVIEITSGAAPLGKDAVDGVLKRFKIPDVRQGYGMTETAGVISIVPLRTEAKNFATVGPLVAGMEAVVVDPTSGERLPPNKQGELWVRGPTVMQGYLNNPEATASTLEKDGWLHTGDLVYIDDGGDIYIVDRLKELIKYKGLQVAPAELEALLLTHPEIEDVAVVPLPDEEAGEVPLAYVVRTKGSYLQERDVIEFVAAQVAPYKKVRKVRFIDAIPKSNAGKILRRELARTPSSRL
MAPSESKHEVTSNLAPDSMSPPPVYLFKSKLPTIEIPDHLTLPEYCLQHSSKLGSKPCLIEMGQSGQATSQNHVTTFGDVIKKARCVATGLEPIAGIKKGDVVMLMIPNSSEFVISFLGAAMRGAIVTTCNPFYKSQEIEKQLSASKAKLIITQLGHIHKLTHIHVPHTFQVMVIDHEPLDIHQGQDQQNHHHLAQDHAPLDPPQFGPILSFSSFFDYSDDYQHDNFELDNCLKTSVFDDVHPDDVAALPYSSGTTGLPKGVMLTHRNLVTSISQQVDGDNPNMYFTPDDIVLCVLPMFHIYSLSIVLCCLRVGATMAIMPKFEIEALLEVVQRHRVTVAPLVPPIVLALAKNPLVQRYDLSSIRMLMCGAAPLSKDLQDSFKARVPHAIVAQGYGMTEAGSVLSMSLAFAKYPSPVKSGSCGTVLRNTVVKLIDPETGLSVPHNQPGEICIKGNQIMKGKFQTDCYLNDSVATSNTIDEDGFLHTGDIGIIDDDDELFIVDRVKEIIKFKGFQVPPAELEGILISHPSVTDAACVPKKDEAAGEVPVAFVVLTKGSEVTENELKQFVANQVIFYKKLHTIIFVDHIPKSPSGKILRKELRKRIEEEHIF
>Azfi_s0013.g013344
MESVAKHGDYDDGGGGEYIFRSKLPDIVIPNHLPLTSYCFEHMEQFSEKPCLVQSDGEKMYTYRDVELYSRRICAGFSKLHISKGDVVMLLLPNCVEFVLLFLGLARAGAASTTCNPFYTSQEITKQVIGSKAKMIITQAAYVEKLAEVAHSVLHSFQVMTIDDEIVAGHLHISSVMHANECECPHVDIHPDDLVALPYSSGTTGLPKGVMLTHKSLVTSIAQQVDGDNPNIHMTPNDVILCVLPMFHIYSLNTVLLCSLRVGATIAVMTKFEISGLLDTVQRYKVTIAPLVPPIVLALAKNPIVEKYDLSSIRMLMSGAAPLGKDLEAAFHSRVPQAIIGQGYGMTEAGPVLAMCLAFAKHPFPVKPGACGTVVRNADVKIIDPETGASLPRNMPGEICIRGDQIMKGYVGDTQATTSTIDEHGFLHTGDIGLIDDDDEVFIVDRVKEIIKFKGFQVPPAELEAILLSHPSILDAACVPIPKSPSGKILRKELRSRLEETTAN
>Azfi_s0027.g023677
WQTERMTTLQGEEEEEIIFKSQLPPSPIPSDLSLPQFVFQNIDEYPDAIAIVDASDGRSFTYDQVRSLSFKVAVGLYLNFNIRRGDVVCVILPNIPEYPFIVFGILTSGGVFTGGNTSSHSDELTKQITHSEAKLIITDAISYQKVQHLVAQIPIIIVGPHDPLEGVTPIEKLYETDTTNVCLPQVLQEDLCALPFSSGTTGVSKGVMITHRNLIANLCSTLFDLERANLTPGQNVTLGLMPFFHIYGFTGICCSTLRSKGTVVVMARFELRLFLNALIDYGVTFAPIVPPIILALVKNPLVNEFDLTKLKLLAVMTAAAPLAPDLQKSFEEKFPGVIIQEAYGLTEHSCITLSHCAPDHVRGNSKKGSVGFILPNLEVKFIDPETGKSLPQNKLGELCVRSQCVTIGYFKNDEATKSTIDEKGWLHTGDVGYIDDDGDIFIVDRIKELIKIPNEEAGEIPVACVVLANGSSLKEDDIIHFVASKVASYKKVRMVFFFDSIPKNASGKILRRNARDTVLKRLQDSTNNN
>Azfi_s0030.g024259
MLLLPNCAEFVFLFLGVAMAGSVVTTANPLYKPAEIHRQVQSCQAKLIVTQAVYVEKLAEECERHIRIMTIDEEKEGHDHVSVLFEEKEGPKNPSVGDEDEADKKSGIRPIEPDDVVALPYSSGTTGLPKGVMLTHRSLLTSVAQQVDGENPNLHFSPDDVVLCVLPLLHIFSLNSVLLCSLRAGSAVAIMQRFEVVALLEFVQRYRISVLAVVPPIVLAITKCPTKHLYDLSSVRKVLSGRRPHGERARGRAPRMLAQCRDRPVSSFLLARSKFIDIGYGMTEAGPVLSMCMSFAKNPSPVKPGSAGTVVRNAEMKVVDTETGKSVSYNQPGEICIRGKQIMKGYLNNPEATTYTIDKDGWLHTGDVGFVDDDDEVFIVDRVKEIIKYKGFQVPPAELEGMLLAHPSIHDAAVIPEPDDAVGEMPVAFVVRSNGSDISEDEIKRYIAAQVVFYKRICKVYFVETIPKSPTGKILRRELRKKLADEIALRKSQSA
>Azfi_s0114.g046013
MSGQVVMSPTPISSLNHTTPPANSHQITAPSVPQQPPSSPKHEHIFRSPLPDIDIPTNLSLPDYIFENASRYPHKPCLIDHSSGRTYTYADVQLLSRRVASGLSRLGISRGHVIMLLLPNCPEFVFLFLGAAMRGAVATTANPLYKPDEIHRQARSSHARLIATQAAYAGKLAQECDPHIRILTVDEALDGVTHISSLLECDAATAFVRDMHYEDDRHFSPDDIVALPYSSGTTGLPKGVMLTHRSLITSLAQQVDGENPNIHYTPDDVVLCVLPLIHIFSLNSVLLCALRAGASVAIMQRFEIVNLLEIIQRHRITMVAVVPPIVLAIAKCPVVDRFDLSSVKKVLSGAAPMGKELEDAFRARLPNAIIGQGYGMTEAGPVISMCLSFAKHPTPVKPASCGTVVRNAEMKIVDTESGASLTYNQPGEICIRGKQIMKGYFNNPDATKFTIDKDGWLHSGDVGYVDDDGEVFIVDRVKEIIKYNGYQVPPAELEAMLIVHLEIRDAAVVSEPDEDVGELPVAFVVRSNGSNISEEEIKKYIAKKVVFYKRIRKVYFVDAIPKSPTGKILRRELRKKLVEDALALRRSTTSHT
>Azfi_s0258.g060636
PNSLSFTASCAAMVNSDGAAAGFDPKTFIFRSPRGELTIPPDLTIPSFLFQTTSARAYHHRVAIADASSHLSLTFSQLRLRIGSAARALSYAGISQGDVVLLLSPNTVHFPVLFFAIVSLGAVATTANPAYTPGEIAKQARDSHAKLILVHTDLLPKISGMNLPTIVIDSDSDSDSGKRSPSHPAAMTYLSDAERVSAGHLPPPVRICQADTAVLLYSSGTTGASKAVALSHLNLIASAVQTNSDAARFSEMDLSFFVPIPFFHVYGLSVILFAQLQRGNTIVTTPRFDLVDMLKAIEEYHVTSLPLVPPIMLALAKHDVALKYDLSSVTEITSGAAPLGKETIEEVASRIKIPNVRQGYGMTETAGFISVFPLRAEAKNFATVGPLVAGMEAVVVDPASGERLPPNKQGELWVRGPNVMQGYLNNPEATAATLEKDGWLHTGDLVYIDDDGYIYIMDRLKELIKYKGLQVAPAELEALLLTHPEIKDVAVVPLPDEDAGEVPFAYVVRAKGSSLQERDVIEFVAPQVAPYKKVRKVSFIAAIPRSSSGKILRRSLNKALNHAPS
>Azfi_s0464.g072360
MVNSDGGGAAAATGFDPKAFIFRSPRGELTIPPDLTIPSFLFQTTSARAYHHRVAIADASSRLSLTFSQLRLRIGSAARALSYVGVSQGDVVLLLSPNSIHFPVLFFAIVSLGAVATTANPVYTPREIERQARDSRAKLILVHPDLLPKLSSGLNLPILVIDSDSGTGKRSSSHCPAVSYLSDAERLSAGHLPPPARIRQADTAVLLYSSGTTSASKAVALSHLNLIASAIQTNSDADRLSETDLSFFVAIPFFHAYGLSVILFAQLQRGNTIVTTPRFDLVDMLKAIEEYHVTSLPLVPPIMLALAKHDVALKYDLSSVTEITSAAAPLGKETIEEVASRFKIPNVRQGYGMTETAGFISVFPLRAEAKNFATVGPLVAGMEAVVVDPTSGERLPPNKQGELWVRGPNVMQGYLNNPEATAATLEKDGWLHTGDLVYIDDDGYIYIMDRLKELIKYKALQVAPAELEALLLTHPEIEDVAVVPLPDEDAGEVPFAYVVRAKGSSLQERDVIEFVAPQVAPYKKVRKVCFIDAIPRSSSGKILRRSLNKALSHAPS
>Azfi_s0464.g072362
MVNSAAAAGFDPKTFIFRSPRGELTIPPDLTIPSFLFQTTSARAYHHRIAIVDPSSNLSLTFSQLQLRIRSAARALSYAGISQGDVVLLLSPNSIHFPVLFFAIVWLGAVATTANPVYTPGEIARQARDSRAKLILVHPDLLPKLSGLNLPILVIDSDSSPGKSSPSHGPAVSYLSDAERLSAGHVPPPVHIRQADTAALLYSSGTTGVSKGVILSHLNFIASAIQINSDAARLGEKDLSFFVVIPFFHVYGLSVILFAQLQRGNTIVTMPRFDFVSMLKAIQDYHVTSLPLVPPIMLALAKHDVALKYDLSSVIEITSGAAPLGKETVEEVSKRFKIPDVRQGYGMTETAGIISIFPLRTEAKNFATVGPLVAGMEAVVVDPTSGERLPPNKQGELWVRGPNVMQGYLNNSEATASTLEKDGWLHTGDLVYIDDDGYIYIMDRLKELIKYKGLQVAPAELEALLLTHPEIEDAAVVPLPDEDAGEVPFAYVVRAKGSSLQERDVIEFVAPQVAPYKKVRKVSFIDAIPKSSSGKILRRELPRTPSSRL
>Azfi_s1020.g095355
MVNSGGFDPKTFIFRSPRGELTIPPDLTIPSFLFQTTSARAYHHRVAIADASSRLSLTFSQLRLRIGSAARALSYAGISQGDVVLLLSPNSIHFPVLFFAIVSLGAVATTANPAYTPREIERQARGSRAKLIVAHPGSLPKLSGLNIPTIVIDSDSGTTKTTTTTTTTTHHHHQHHHRHHHPDQRLLSDAERLSAAAGHSPPPVRIRQVDTAALLYSSGTTGPSKAVPLSHLNLIASAIQTNSDAARLGHHDLCFFAVTPFCHVYGLSFLLLAQLQRGNTIVTIPRFNFVDMLKAIQEYHVTSLSLVPPVMLALAKHDAALRYDLSSVIEITSGAAPLGKDAVDGVLKRFKIPDVRQGYGMTETAGVISIVPLRTEAKNFATVGPLVAGMEAVVVDPTSGERLPPNKQGELWVRGPTVMQGYLNNPEATASTLEKDGWLHTGDLVYIDDGGDIYIVDRLKELIKYKGLQVAPAELEALLLTHPEIEDVAVVPLPDEEAGEVPLAYVVRTKGSYLQERDVIEFVAAQVAPYKKVRKVRFIDAIPKSNAGKILRRELARTPSSRL
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University