Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Avicennia marina
Species name
Avicennia marina is a species of eudicot in the family Acanthaceae.
Species info
Gene sequence info
Avicennia_marina.COMT.fa
Download
>jg22736.t1
MENTMISASNGNGEDNEAGVEAITASTSYIFPWVLNAAVQLDVFEIIAKAGDGARLSPSEIASRLPTNGRGEEAAAPLDSMLRLLASYSLLTCSISEDADGGAIERRYGLAPSGKFFARDESGMSLARLQQLGNHQAETMEIGHHSKDAVLGGGVLFERLYGKSFYEYMNSSPEHGKMFHDAMRAHSVFILDKVLETYHGFEGISSIVNVAGGDGATLEMIISKHPSIRGINYDLPEVIQNAPPCEGIEHIGGDMFVEVPQGDTILLKYTLHNWSDEKCIQVLRNCHKALPKNKMGKVIALECVLPEVPRADVHSKFASQMDNAMLILFGAKQRTQHEFEYMAKEAGFAELKVVCYVRGLWVMEFIKPN
>jg22735.t1
METTKISASNGNGEDNEAGVEAITASTSYIFPWVLNAAVQLDVFEIIAKAGDGARLSPSEIASRLPTNGRGEEAAAPLDSMLRLLASYSLLTCSTSENADGDAIERRYGLAPSGKFFARDESGMSLAKLQQLGNHQAETMELGHHSKDAVLGGGVLFERLYGKSFYEYMNSSPEHGKMFHDAMRAHSVFILGKVLETYHGFEGISSIVNVAGGDGATLEMIISKHPSIRGINYDLPEVIQNAPPCEDIVHRNSVHPQAGAASSDSCRRGEVHDPDPESCSGWVVISGHEDGVLRADDEREIVEWHISVLLQFGSRRVLVVSSPSAAEECLTKNDVVFANRPHLLAGKHLGYNYVSVVWSSYGDHWRNLRKISSIEILSTHRLELLHRIRADEVKSMIRTLNRARDGWLSVDMKTVFFELTMNVVMRMIAGKRYYGQNVVEVEGAWRFREIVTETMRLGTPNMADFLPLVRWLGVGGVEKGQVELQRKRDAFMQELIEERKKRFFSYGGGEEAEGKTRTIIELLLGLREKEPEYYTDALIRSQMMVY
>jg2113.t1
MDSSEEEACLFAMQLASASVLPMVLKSAMELDLLELIKKAGPGAFVSPAELAAQLPTANPEAHVMLDRILRLLASYSVLNCSLKRLPNGGVERLYGLAPVCKFLTKNDDGVSMAPLLLMNQDKVLMESWYHLKDAVLDGGIPFNKAYGMTAFDYHGTDPRFNNVFNQGMSNHSTIMMKKILETYKGFEGVKTVVDVGGGTGATLNMIVSKYPNIKGINFDLPHVVVDAPSYPGVEHVGGDMFVSVPKGDAIFMKWICHDWSDDHCLKFLKNCYDALPENGKVILAECILPEAPDSCLETQNVVHVDVIMLAHNPGGKERTEKEFEALAKAAGFKQFHRVCGAYKYSWIMELRK
>jg13820.t1
MDSSDEEACLFSMQLASASVLPMVLKAALELDLLELIKKAGPGAFVSPAELAAQLPTANPEAPVMLDRILRLLSSYSVLNCSLKTLPDGGVRRLYGLAPVCRFLTKNDDGVSMAPLLLMNQDKVLMESWYHLKDAVLDGGIPFNKAYGMTAFEYHGRDPRFNKVFNQGMSNHSTIIMKKILETYDGFEGLKTVVDVGGGTGATLNMIISKYPSIKGINFDLPHVVEDAPSYPGVEHVGGDMFVSVPKGDAIFMKWICHDWSDEHCLQFLKECHEALPENGKVILAECLLPEAPDTGLPTKNVVHVDVIMLAHNPGGKERTEKEFQALAKGAGFKDFRKVCCAYNSWIMELFK
>jg27409.t1
MTPNVSLSLNPALMDPWHRLSAWYKNDSPASFETAHGRTVWQFLRQDPVLNGVFNECMESNSRFVGSVLTQDCRHVFQGLKSMVDVGGRTGTVAKAIVDAFPGLKCIVLDLPHVVVGLEGSTNLTFESGDMFESIPPADAVFLKWIMHDWPDEECLTILKKCKEAIPSKEKGGKEERGLRKIGKSSAAPPASQAT
>jg32652.t1
MPMSLDAVVRLNVDDTIWQGGSNALPPPILKISSTFSACLSAMGLFMNTLHKIVPKEVGKTLVIGENSLSYASYVLWHHQDALLRAWPLVHEAVVDPWSELPFMKALLDGYHGFHRIETLVDVSRSLGDCLKMIVNKNPNIERGANFDLPEWILTALTDDECKQVLKNCYSALPLGGKVIGCEPVLPNGGDDSHRSRTLIERDIFVMTILGIRGNKGQIWNIWRLASP
>jg32445.t1
MEAESTIELEAYHQAKTGALFGAATMLGAAAAGHAPAPWQALGDRIGQAYQIVDDIRDSTLASQALGKPAGQDSRMGRPSAVATYGLVAARARYESLLDDIVAEIPLCPGAEAHTSSYPSRIGRVLPGIVRRAGRLNIKSFKSVAVRLARWTRWRWLAWRNARLADPAFQRWATRFRPTRGVARADTRRLFDLCAGFVYSQAMIAEQALAVCDLSDRHRLIDIGGGAGVFARHVTARFKAISVTVLDLPAVAEQASTALASAEPDTRIQCRGADMWRAPWSPTDAEPPDAISFIRILHDHEDAPVERLLAKAYDTLAPGGLLLIARYAGGRAGRCRLFRVLSMGDGSGPSAQRR
>jg8440.t1
MLDPILTDPWHRVSEWFKTDLPTPFVTAHGTTFWEQVGRNARLNQSFNEGMASDARLVTSVITRDCRQVFEGLKSMVDVGGGTGAVAKIITDAFPGLKCTVLELPHVVAGLEGSEKLDFVGGDMFESIPQGGFSFFVLLPPLCGNGTGVGCGGAGRLSWLWEALGAVGDARGQGQALEGRGGIDTGSSCCSSCGWLPMAGLGGDGIASDEQRSTGRAAAEALCAGGSARATLEGVGRCGAADAAAMPGAACARPVVLGEALQRTN
>jg41202.t1
MFHDAMRAHSVFILDKVLETYHGFEGISSIVNVAGGDGATLEMIISKHPSIRGINYDLPEVIQNAPPCEX
>jg33897.t1
MSTICSPSLYLLPLFLEDIDFTDNSTGIRSPQRRHRCTCCVASMDQSEEETFSFALQLVAGSALPMALKSAMELNLLELIRKVGPGASVSASELAAQLPTNNPHAASIIDRILGFLAASSVLSCSLKPLPDGGVGRLYSLAPVCKYFARNEDGVSLASASFTNQDRVTMECWSQIPVEFGGGIGASLKMIVSKYPRIKAINFDLPHVIQDAPSYLGVEHIGGDIFVSVPKVDAIFMKVILIRGREMSEKEFEALAKQAGFKQMEKVCCAFNVWIMEFRK
>jg33898.t1
MDQSEEETFLFALQLSTGSALPMALKSAMELNLLELIKKAGPEASVSASELAAQLPTNNPHAASMIDRILGFLAASSVLSCSLKPLPDGGVERLYSLAPVCKYLTRNEDGVSLAPVSFMIQDRVMMECWYHIKDAVLEGGIPFDKAHGMNAFEYPATDPRFNKVFNQAMYESSTIYMKKILEEYRGFEGLKSLVDVGGGIGASLKMIVSKYPCIKAINFDLPHVIQNAPSYPGVEHVGGDMFVSVPKADAIFMKWICHDWSDAHCQKLLKNCHEALPENGKVIVAETILPEHPTNGVAFSQAAQGDVMMLAFNPGGRERSERGYEALAREAGFKQMEKVCCAFNVWIMEFRK
>jg31037.t1
MFEAIPKADAAFLMFVLHDWSDDDCIRILKKCLEAIPKSTGKVIIAEAVIEEGDEDKYSDVRLALDLVMLAHTEKGKERTLKEWEYVVKAAGFTRTNFPYSLSRFPFTAPSLLPINNTVASSPSTPTPKAGETRDREKLPSTLFSRAAAQPTTFESVTAFSFLQPTEMARSFSNAKTVSAFLANEISALATFRIRGYAAESQGVVSGGARSGAPNVMLKKGSEESGKTAWVPDPKTGYYRPESEEKAVDPAELREMLIKNKSRGQ
MENTMISASNGNGEDNEAGVEAITASTSYIFPWVLNAAVQLDVFEIIAKAGDGARLSPSEIASRLPTNGRGEEAAAPLDSMLRLLASYSLLTCSISEDADGGAIERRYGLAPSGKFFARDESGMSLARLQQLGNHQAETMEIGHHSKDAVLGGGVLFERLYGKSFYEYMNSSPEHGKMFHDAMRAHSVFILDKVLETYHGFEGISSIVNVAGGDGATLEMIISKHPSIRGINYDLPEVIQNAPPCEGIEHIGGDMFVEVPQGDTILLKYTLHNWSDEKCIQVLRNCHKALPKNKMGKVIALECVLPEVPRADVHSKFASQMDNAMLILFGAKQRTQHEFEYMAKEAGFAELKVVCYVRGLWVMEFIKPN
>jg22735.t1
METTKISASNGNGEDNEAGVEAITASTSYIFPWVLNAAVQLDVFEIIAKAGDGARLSPSEIASRLPTNGRGEEAAAPLDSMLRLLASYSLLTCSTSENADGDAIERRYGLAPSGKFFARDESGMSLAKLQQLGNHQAETMELGHHSKDAVLGGGVLFERLYGKSFYEYMNSSPEHGKMFHDAMRAHSVFILGKVLETYHGFEGISSIVNVAGGDGATLEMIISKHPSIRGINYDLPEVIQNAPPCEDIVHRNSVHPQAGAASSDSCRRGEVHDPDPESCSGWVVISGHEDGVLRADDEREIVEWHISVLLQFGSRRVLVVSSPSAAEECLTKNDVVFANRPHLLAGKHLGYNYVSVVWSSYGDHWRNLRKISSIEILSTHRLELLHRIRADEVKSMIRTLNRARDGWLSVDMKTVFFELTMNVVMRMIAGKRYYGQNVVEVEGAWRFREIVTETMRLGTPNMADFLPLVRWLGVGGVEKGQVELQRKRDAFMQELIEERKKRFFSYGGGEEAEGKTRTIIELLLGLREKEPEYYTDALIRSQMMVY
>jg2113.t1
MDSSEEEACLFAMQLASASVLPMVLKSAMELDLLELIKKAGPGAFVSPAELAAQLPTANPEAHVMLDRILRLLASYSVLNCSLKRLPNGGVERLYGLAPVCKFLTKNDDGVSMAPLLLMNQDKVLMESWYHLKDAVLDGGIPFNKAYGMTAFDYHGTDPRFNNVFNQGMSNHSTIMMKKILETYKGFEGVKTVVDVGGGTGATLNMIVSKYPNIKGINFDLPHVVVDAPSYPGVEHVGGDMFVSVPKGDAIFMKWICHDWSDDHCLKFLKNCYDALPENGKVILAECILPEAPDSCLETQNVVHVDVIMLAHNPGGKERTEKEFEALAKAAGFKQFHRVCGAYKYSWIMELRK
>jg13820.t1
MDSSDEEACLFSMQLASASVLPMVLKAALELDLLELIKKAGPGAFVSPAELAAQLPTANPEAPVMLDRILRLLSSYSVLNCSLKTLPDGGVRRLYGLAPVCRFLTKNDDGVSMAPLLLMNQDKVLMESWYHLKDAVLDGGIPFNKAYGMTAFEYHGRDPRFNKVFNQGMSNHSTIIMKKILETYDGFEGLKTVVDVGGGTGATLNMIISKYPSIKGINFDLPHVVEDAPSYPGVEHVGGDMFVSVPKGDAIFMKWICHDWSDEHCLQFLKECHEALPENGKVILAECLLPEAPDTGLPTKNVVHVDVIMLAHNPGGKERTEKEFQALAKGAGFKDFRKVCCAYNSWIMELFK
>jg27409.t1
MTPNVSLSLNPALMDPWHRLSAWYKNDSPASFETAHGRTVWQFLRQDPVLNGVFNECMESNSRFVGSVLTQDCRHVFQGLKSMVDVGGRTGTVAKAIVDAFPGLKCIVLDLPHVVVGLEGSTNLTFESGDMFESIPPADAVFLKWIMHDWPDEECLTILKKCKEAIPSKEKGGKEERGLRKIGKSSAAPPASQAT
>jg32652.t1
MPMSLDAVVRLNVDDTIWQGGSNALPPPILKISSTFSACLSAMGLFMNTLHKIVPKEVGKTLVIGENSLSYASYVLWHHQDALLRAWPLVHEAVVDPWSELPFMKALLDGYHGFHRIETLVDVSRSLGDCLKMIVNKNPNIERGANFDLPEWILTALTDDECKQVLKNCYSALPLGGKVIGCEPVLPNGGDDSHRSRTLIERDIFVMTILGIRGNKGQIWNIWRLASP
>jg32445.t1
MEAESTIELEAYHQAKTGALFGAATMLGAAAAGHAPAPWQALGDRIGQAYQIVDDIRDSTLASQALGKPAGQDSRMGRPSAVATYGLVAARARYESLLDDIVAEIPLCPGAEAHTSSYPSRIGRVLPGIVRRAGRLNIKSFKSVAVRLARWTRWRWLAWRNARLADPAFQRWATRFRPTRGVARADTRRLFDLCAGFVYSQAMIAEQALAVCDLSDRHRLIDIGGGAGVFARHVTARFKAISVTVLDLPAVAEQASTALASAEPDTRIQCRGADMWRAPWSPTDAEPPDAISFIRILHDHEDAPVERLLAKAYDTLAPGGLLLIARYAGGRAGRCRLFRVLSMGDGSGPSAQRR
>jg8440.t1
MLDPILTDPWHRVSEWFKTDLPTPFVTAHGTTFWEQVGRNARLNQSFNEGMASDARLVTSVITRDCRQVFEGLKSMVDVGGGTGAVAKIITDAFPGLKCTVLELPHVVAGLEGSEKLDFVGGDMFESIPQGGFSFFVLLPPLCGNGTGVGCGGAGRLSWLWEALGAVGDARGQGQALEGRGGIDTGSSCCSSCGWLPMAGLGGDGIASDEQRSTGRAAAEALCAGGSARATLEGVGRCGAADAAAMPGAACARPVVLGEALQRTN
>jg41202.t1
MFHDAMRAHSVFILDKVLETYHGFEGISSIVNVAGGDGATLEMIISKHPSIRGINYDLPEVIQNAPPCEX
>jg33897.t1
MSTICSPSLYLLPLFLEDIDFTDNSTGIRSPQRRHRCTCCVASMDQSEEETFSFALQLVAGSALPMALKSAMELNLLELIRKVGPGASVSASELAAQLPTNNPHAASIIDRILGFLAASSVLSCSLKPLPDGGVGRLYSLAPVCKYFARNEDGVSLASASFTNQDRVTMECWSQIPVEFGGGIGASLKMIVSKYPRIKAINFDLPHVIQDAPSYLGVEHIGGDIFVSVPKVDAIFMKVILIRGREMSEKEFEALAKQAGFKQMEKVCCAFNVWIMEFRK
>jg33898.t1
MDQSEEETFLFALQLSTGSALPMALKSAMELNLLELIKKAGPEASVSASELAAQLPTNNPHAASMIDRILGFLAASSVLSCSLKPLPDGGVERLYSLAPVCKYLTRNEDGVSLAPVSFMIQDRVMMECWYHIKDAVLEGGIPFDKAHGMNAFEYPATDPRFNKVFNQAMYESSTIYMKKILEEYRGFEGLKSLVDVGGGIGASLKMIVSKYPCIKAINFDLPHVIQNAPSYPGVEHVGGDMFVSVPKADAIFMKWICHDWSDAHCQKLLKNCHEALPENGKVIVAETILPEHPTNGVAFSQAAQGDVMMLAFNPGGRERSERGYEALAREAGFKQMEKVCCAFNVWIMEFRK
>jg31037.t1
MFEAIPKADAAFLMFVLHDWSDDDCIRILKKCLEAIPKSTGKVIIAEAVIEEGDEDKYSDVRLALDLVMLAHTEKGKERTLKEWEYVVKAAGFTRTNFPYSLSRFPFTAPSLLPINNTVASSPSTPTPKAGETRDREKLPSTLFSRAAAQPTTFESVTAFSFLQPTEMARSFSNAKTVSAFLANEISALATFRIRGYAAESQGVVSGGARSGAPNVMLKKGSEESGKTAWVPDPKTGYYRPESEEKAVDPAELREMLIKNKSRGQ
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University