Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Averrhoa carambola
Species name
Averrhoa carambola is a species of eudicot in the family Oxalidaceae (wood-sorrel family).
Species info
Gene sequence info
Averrhoa_carambola.HIDH.fa
Download
>Yangtao2006663
MAAISYDPRHTINQVGKNQVQHGFVVEEIEGLIRVYKDGYVERPQIIPIVNSAVTDVNVTARDVVIDKFTNLWARIYVPSCHGKLLPLLVYFHGGGFCVASAAWSCYHEFLANLAAKAGCVIISVNYRLAPENRLPTAYDDGVNTLMWVKQRALSGCSEQKWWQSHCNISNLFLAGDSAGANIVYNVATRLQDSNAIKPLCLKGLILIQPFFGGETRTNSEKHTNQPPNSALTLSASDTYWRLSLPLGATRDHPWCNPLAGGGVARLREMRLPSTLVCVSEMDILKDRNLDFCSALASAGKRVDTYVYKGVGHAFQILRNSQYSQIRVQELLSNLKAFVNQ
>Yangtao2019597
MVFERKLVDEVSGWLRLYDDGSVDRTWTGPPEVKFMAEPVPSHEDKFIDGVSIKDVTIDSSSGLKVRIYLPEPKDDQDQRIKKLPIIVHFHGGGFCISQADWFMYYHVYTKLAKTAQAVVVSVYLRLAPENRLPAACDDGFSALLWLNSLATAESHEPWLNGVGDFNRVFLIGDSSGGNVVHEVAARAGHVDICPVRLVGAIPIHPGFVRSERSRSELEQPESPFLTLDMVDKFLGLALPVGCTKEHQITCPMGPAAPPMEGLNLPPILLCNDLIKDTEMEYYEAMKKANKDVELLINSGMGHSFYLNKIAVDLDPNTRAQTAGLFQGIEEFINKH
>Yangtao2011911
MSNTTTTNPPHEVDECRGVLRVYSDGSIWRSSKPSFNVPVHDDGSVLWKDVAFDAVHGLHLRLYKPASPSSNKLPFFYYIHGGGFCIGSRTWPNCQNYCFRLALELQAVVISPDYRLAPENRLPAAIEDGFVAVKWLQAQAISDTPDSWLTDVADFGNLFISGDSAGGNIAHNLAVRLGAGSPELAPVQVKGYVLLAPFFGGTARSRSEAEGPKDAFLNLELIDRFWRLSIPIGDTTDNPLVNPFGPHSPSLEAVALDPILVVCGGADLLKDRAEDYANRLKNWGKEAEYAEFEGQQHGFFTIYPDSDPSKNLMLLIQKFIHQHSTS
>Yangtao2023330
MRRRRMAATTAIDPSLSLQINSKDSLHRHHGAVVEEIDGLIRVYKDGHVERPQIVPCVTTTLAADLGVTSQDIVIDEYTNIWARFYVPICNGYGNNKLPLLVYFHGGGFCVGSAAWCCYHQFLAKLAKSSCCLIMSVNYRLAPENPLPAAYEDGFKALLWLKQEALRDPSHQYSWTKQCNFSNIFLAGDSAGANIAYNVTTRLGSNEITALKPLTFKGLISIQPFFGGESRTNSEKYMAQPPRSALDLAAADTYWRLALPLGSNRDHPWCNPLLSLKLEGVSRLRLLPKIMVCISELDILKDRNLEFCSALCGAGVRVEQVMYKGVGHAFQVLSKSQISQSRTSDMMDHIKAFITR
>Yangtao2008398
MSSSTNEIAHEHVPYFRAYKDGRIERFFGNDFVPPSSNAFTVSSKDVAIAPETGVSARIFMPINTINPSQKLPLLVYFHGEASIWAPQHLVPAQYEDSWAALKWVASHFNNNQGPESWLNDYADFDRFFLAGDSAGANLVHNIAVQAGVEDLNGVKLSGICLIQPYFGRKCSGVDKCWLFVCPNTSGFNDPRINPAMDSRLSSLRSTTRVLVAVAENDSLRDRGVFYYEALKNSGWCGEVELVETQGEDHVFHLFKPESDKALALVTKLASFINQGIGTCSNK
>Yangtao2008399
MDPKSKEIAHDFAPFLRIYKDGGVERLLGTVTVPPSLDPKTNVESKDVIYSPQNNLYCRLYKPQNTNHCQKLPLLVFCHGGAFCIETASSPTYHNYLNTLVSEANIIAVSVDYRRAPEDPLPAAYEDSWTALKWVASHVNGDCNNEDWINNHVDFQKVFFAGDSAGANIVHNMGLKLGKEKLEGVNVVGLILVHPYFWGNEPVGSETKEEALRLKAEVIWHLACPTTSGCDDFWINPIIDPDLKSLGGTKVLVCVSEKDYLSERAKVYSEKLAKSGWGGSVEIMESKGEDHVFHLFNPTSENAVALMKRIISFINQ
>Yangtao2008402
MDSNTTEIAQDFAPFLRIHKDGRIERLAGTATVPPCLDPKTNVESKDVIHSPQNNLYCRLYKPQINSNQDQKLPLLVYFHGGGFVIMTASSSTYHNYINTLVSEANIIAVSVDYRRAPEDPLPAAYEDSWTAIKWVASHVNGDGNEHWLNNHVDFQKVFFAGDSAGANIVYNMGMKLGKEEKLEGVNVVGLILVHPYFWGNEPVGNETKDVAIRSKIGGVWHLCLFGVAEKDVLTERAKVCSEKLAKSGWGGSVEIMESKGEDHVFHLFNPACENAVPMMKKLVSFINQ
>Yangtao2008400
MDPNTTEIAHDFAPFLRIYKDGRVERLIGTATVPPSLDPITNVESKDVIYSPQNNLYCRLYKPQNTNQGQKLPLIVYIHGGGFCIETASSPTYHNYLNPLVSEAKIITVSVDYRRAPEDPLPAAYEDSWAALKWVASHVNGDGNEDWINNNVDFQKVFLAGDSAGANIVHNVGLKLGKEKLEGVNVVGLILMHPFFWGNEPVGNETRDVDARLKAAGIWHLACPTTSGCDDFWINPINDPDLKSLGCNKVLVCVAEKDTLTERGKVYCEKLASSGWVGSVEIMEAKGEDHVFHLFNPTCENSVALTEKLVSFINQEKHHQHKILLSVSQSSWLLVREVWHYCVVVFFGFVFIENNANVF
>Yangtao2008401
MDSNTTEIVHDFAPYFRISKDSHIERLVGTDTVPPSLDPKTNVDSKDVIYSPQNDLYCRVYKPQNTNQDQKLPLLVYFHGGGFVIMTASSSTYHNYINTLVSEANIIAVSVDYRRAPEDPLPAAYEDSWTALKWVASHVNGDGNEDWLNNHVDFQKVFFAGDSAGGNIVHNMGLKLGKEEKLEGVNVEGLILVHPYFWGNETAGNETKDVAIRSKMEILWRLACPTTSGCDDFLINPINDPDLKSLGCNKVLVCVAEKDILTEKGKVYYEKLAKSGWDGSLEIMESKEEDHTFHLVEPTCGNAVALMKKMVSFINLDKASSS
>Yangtao2008404
MESSSNDVVHDFPHFFKVYKDGRIERHRYADMDFVPTGLDPNTGVQTKDVLVGPDASSKSPLAPENPLPIAYEDSWAGLQWVSTHSNGAGPEPWLNQHADFGRERNDLYKYMCPTSSGCDDDPKLNPAVDPNLKSMGCERVIVMVAETDFLRAAGVAYYETLKNSDWEGTVEFYESEGEDHCFHLFNPNSENARPVMNKMSDFIKQN
>Yangtao2008405
MASSNNEEAFNFPFFKLYKDGRIERRESKLYFVPAGLDPNTGVQTKDVVVSPETGVKARIFKPKTHNPDQKLPLLVHYHGGAFCVGSAFDSGTSFFLTHIVSQANAIAISIDYRLAPENPLPIPHEDSWAGLQWVAAHSKGVGPEPWLNKHADLRRVFLVGDSAGANIAHYVAIQAGVMKPADLNTVGLLMVHPFFGVKEDNEIYRVWSRKVPEKDKLRPRGVAYYETLIKSEWSGFVEWFESKGEDHVFHLFNHSSQNVEPLMKKIADFIKQ
>Yangtao2003788
MSLVAEVPDYLQVFSDGSIKRFAPEIVHTSPESSNGYKSKDVTIDPSRQITARLFLPDAAGSPASLPVLVYFHGGGFCVAMRNKTSQVKIKGMLPIHPFFGSEKRTEKEMANGPEGAVAMNDLFWRLSIPEGSNRDYFGCNLEMQDVSADEWCQFPAVVVFVAGLDFLKERGEMYAEFLQKKGVKEVKLIEEEGESHVFFVFHPKSQATRLLQQQMSKFIKSH
>Yangtao2009909
MGSNNQEIAIDVFPWLQVYKDGTINRLAGTEVVPAGLDPETGVFSKDIVIIPETGVSARLYRHNSRKDGEKKLPLVVYFHGGAFLIASTGEPKYHTSLNKLVAKANVIVASIDYRLAPEHPLPTAYDDSWGAIQWVAAHKGDGGHEPWLKDDVDFDQVFLAGDSAGASIAHHLLTKGLQLKISALRGLQFNISGIAMILPYFWGKEPIGAEVNDPFRREMVNKWWSFVCQSDKGNDDPLINPFVEGSPSLKVLPCDRVFVAVAGSDILRDRGWLYYDQLVKSEWQGKAEIMEIEGEDHVFHIIKPDSEKAKSLIKRWSSFINKGKESSSCV
>Yangtao2019070
MDSTTKEILKELPALIKLYKDGSVERLFCSPNVPSSIDQETGVTSKDITISQDPLVSARLYLPKLVDQSPQKLPILVYFHGGGFCLGSAFTFIEHRYLNKTVSQAQVLAVSIEYRLAPEHPLPAAYEDSWSALQWVASHSVNNSNEVVDKDEWLLNYADFDRLYIGGDSAGANIVHNIAIRAGIETLKCGVKILGAFLSHPFFWGSEAVGRETSANRERDWAYLTWDLVYPSAENGIDNFMINPAGSEAKSLALLALSRLLICVAEQDVFRDRGVWYCDLVKESGWRGEMELFEVKGEGHVFHVLNPQTENAESMFKRLAAFMQ
>Yangtao2019069
MATKTRENPETESVLSKDISISEAPQISARLYLPKLAQPNQKLPILVYFHGGGFCIESAFTLFTHRYLNMLVAQAQVSAVSVEYRQAPEHPLPAAYEDCWAALQWVTSHSSTTAQNEHHNAKDPWISNHGDFDRLFIGGDIAGGNIVHNIAMRAGVESLNCNVNILGDFLSHPYFWGSKPVGSESNANLEKKFCRLVWDFVYPLAENGIDNYMINPVGPGAPSLEGLGCSRLLICVAEKDELRDRGVWYCDLVKESGWRGEVELFEVKGEDHAFHLFNPETENAMNMFKRLASFLLN
>Yangtao2019068
MASVTKEVDRECLPFVRVYKDGSVERPSGSPIVPPSLEDPETGVSSKDVTISQDPSISARLYLPKHTKQDQKLPILVYFHGGGFCVESAFSLVETKLMNSLVSEAKVVGISIEYRLAPEHPIPVVYDDCWAGLQWVASHSMHDDGKDKDPWIKNHGDFDRLFSGGDSSGGNIVHNIAMRAGSEDLQGGVKLSGAFLTHPYFWGSKPIGSEKSEGHDQSVPRQVWDFLYPSAPGGIDNPMMNPLVRGAPSLAGLGCRRLLVSVAELDVLKDRGISYYNALKESGWKGEGKLIQVDGEDHAFHILNYGTETSKKLIQRLASFLSK
MAAISYDPRHTINQVGKNQVQHGFVVEEIEGLIRVYKDGYVERPQIIPIVNSAVTDVNVTARDVVIDKFTNLWARIYVPSCHGKLLPLLVYFHGGGFCVASAAWSCYHEFLANLAAKAGCVIISVNYRLAPENRLPTAYDDGVNTLMWVKQRALSGCSEQKWWQSHCNISNLFLAGDSAGANIVYNVATRLQDSNAIKPLCLKGLILIQPFFGGETRTNSEKHTNQPPNSALTLSASDTYWRLSLPLGATRDHPWCNPLAGGGVARLREMRLPSTLVCVSEMDILKDRNLDFCSALASAGKRVDTYVYKGVGHAFQILRNSQYSQIRVQELLSNLKAFVNQ
>Yangtao2019597
MVFERKLVDEVSGWLRLYDDGSVDRTWTGPPEVKFMAEPVPSHEDKFIDGVSIKDVTIDSSSGLKVRIYLPEPKDDQDQRIKKLPIIVHFHGGGFCISQADWFMYYHVYTKLAKTAQAVVVSVYLRLAPENRLPAACDDGFSALLWLNSLATAESHEPWLNGVGDFNRVFLIGDSSGGNVVHEVAARAGHVDICPVRLVGAIPIHPGFVRSERSRSELEQPESPFLTLDMVDKFLGLALPVGCTKEHQITCPMGPAAPPMEGLNLPPILLCNDLIKDTEMEYYEAMKKANKDVELLINSGMGHSFYLNKIAVDLDPNTRAQTAGLFQGIEEFINKH
>Yangtao2011911
MSNTTTTNPPHEVDECRGVLRVYSDGSIWRSSKPSFNVPVHDDGSVLWKDVAFDAVHGLHLRLYKPASPSSNKLPFFYYIHGGGFCIGSRTWPNCQNYCFRLALELQAVVISPDYRLAPENRLPAAIEDGFVAVKWLQAQAISDTPDSWLTDVADFGNLFISGDSAGGNIAHNLAVRLGAGSPELAPVQVKGYVLLAPFFGGTARSRSEAEGPKDAFLNLELIDRFWRLSIPIGDTTDNPLVNPFGPHSPSLEAVALDPILVVCGGADLLKDRAEDYANRLKNWGKEAEYAEFEGQQHGFFTIYPDSDPSKNLMLLIQKFIHQHSTS
>Yangtao2023330
MRRRRMAATTAIDPSLSLQINSKDSLHRHHGAVVEEIDGLIRVYKDGHVERPQIVPCVTTTLAADLGVTSQDIVIDEYTNIWARFYVPICNGYGNNKLPLLVYFHGGGFCVGSAAWCCYHQFLAKLAKSSCCLIMSVNYRLAPENPLPAAYEDGFKALLWLKQEALRDPSHQYSWTKQCNFSNIFLAGDSAGANIAYNVTTRLGSNEITALKPLTFKGLISIQPFFGGESRTNSEKYMAQPPRSALDLAAADTYWRLALPLGSNRDHPWCNPLLSLKLEGVSRLRLLPKIMVCISELDILKDRNLEFCSALCGAGVRVEQVMYKGVGHAFQVLSKSQISQSRTSDMMDHIKAFITR
>Yangtao2008398
MSSSTNEIAHEHVPYFRAYKDGRIERFFGNDFVPPSSNAFTVSSKDVAIAPETGVSARIFMPINTINPSQKLPLLVYFHGEASIWAPQHLVPAQYEDSWAALKWVASHFNNNQGPESWLNDYADFDRFFLAGDSAGANLVHNIAVQAGVEDLNGVKLSGICLIQPYFGRKCSGVDKCWLFVCPNTSGFNDPRINPAMDSRLSSLRSTTRVLVAVAENDSLRDRGVFYYEALKNSGWCGEVELVETQGEDHVFHLFKPESDKALALVTKLASFINQGIGTCSNK
>Yangtao2008399
MDPKSKEIAHDFAPFLRIYKDGGVERLLGTVTVPPSLDPKTNVESKDVIYSPQNNLYCRLYKPQNTNHCQKLPLLVFCHGGAFCIETASSPTYHNYLNTLVSEANIIAVSVDYRRAPEDPLPAAYEDSWTALKWVASHVNGDCNNEDWINNHVDFQKVFFAGDSAGANIVHNMGLKLGKEKLEGVNVVGLILVHPYFWGNEPVGSETKEEALRLKAEVIWHLACPTTSGCDDFWINPIIDPDLKSLGGTKVLVCVSEKDYLSERAKVYSEKLAKSGWGGSVEIMESKGEDHVFHLFNPTSENAVALMKRIISFINQ
>Yangtao2008402
MDSNTTEIAQDFAPFLRIHKDGRIERLAGTATVPPCLDPKTNVESKDVIHSPQNNLYCRLYKPQINSNQDQKLPLLVYFHGGGFVIMTASSSTYHNYINTLVSEANIIAVSVDYRRAPEDPLPAAYEDSWTAIKWVASHVNGDGNEHWLNNHVDFQKVFFAGDSAGANIVYNMGMKLGKEEKLEGVNVVGLILVHPYFWGNEPVGNETKDVAIRSKIGGVWHLCLFGVAEKDVLTERAKVCSEKLAKSGWGGSVEIMESKGEDHVFHLFNPACENAVPMMKKLVSFINQ
>Yangtao2008400
MDPNTTEIAHDFAPFLRIYKDGRVERLIGTATVPPSLDPITNVESKDVIYSPQNNLYCRLYKPQNTNQGQKLPLIVYIHGGGFCIETASSPTYHNYLNPLVSEAKIITVSVDYRRAPEDPLPAAYEDSWAALKWVASHVNGDGNEDWINNNVDFQKVFLAGDSAGANIVHNVGLKLGKEKLEGVNVVGLILMHPFFWGNEPVGNETRDVDARLKAAGIWHLACPTTSGCDDFWINPINDPDLKSLGCNKVLVCVAEKDTLTERGKVYCEKLASSGWVGSVEIMEAKGEDHVFHLFNPTCENSVALTEKLVSFINQEKHHQHKILLSVSQSSWLLVREVWHYCVVVFFGFVFIENNANVF
>Yangtao2008401
MDSNTTEIVHDFAPYFRISKDSHIERLVGTDTVPPSLDPKTNVDSKDVIYSPQNDLYCRVYKPQNTNQDQKLPLLVYFHGGGFVIMTASSSTYHNYINTLVSEANIIAVSVDYRRAPEDPLPAAYEDSWTALKWVASHVNGDGNEDWLNNHVDFQKVFFAGDSAGGNIVHNMGLKLGKEEKLEGVNVEGLILVHPYFWGNETAGNETKDVAIRSKMEILWRLACPTTSGCDDFLINPINDPDLKSLGCNKVLVCVAEKDILTEKGKVYYEKLAKSGWDGSLEIMESKEEDHTFHLVEPTCGNAVALMKKMVSFINLDKASSS
>Yangtao2008404
MESSSNDVVHDFPHFFKVYKDGRIERHRYADMDFVPTGLDPNTGVQTKDVLVGPDASSKSPLAPENPLPIAYEDSWAGLQWVSTHSNGAGPEPWLNQHADFGRERNDLYKYMCPTSSGCDDDPKLNPAVDPNLKSMGCERVIVMVAETDFLRAAGVAYYETLKNSDWEGTVEFYESEGEDHCFHLFNPNSENARPVMNKMSDFIKQN
>Yangtao2008405
MASSNNEEAFNFPFFKLYKDGRIERRESKLYFVPAGLDPNTGVQTKDVVVSPETGVKARIFKPKTHNPDQKLPLLVHYHGGAFCVGSAFDSGTSFFLTHIVSQANAIAISIDYRLAPENPLPIPHEDSWAGLQWVAAHSKGVGPEPWLNKHADLRRVFLVGDSAGANIAHYVAIQAGVMKPADLNTVGLLMVHPFFGVKEDNEIYRVWSRKVPEKDKLRPRGVAYYETLIKSEWSGFVEWFESKGEDHVFHLFNHSSQNVEPLMKKIADFIKQ
>Yangtao2003788
MSLVAEVPDYLQVFSDGSIKRFAPEIVHTSPESSNGYKSKDVTIDPSRQITARLFLPDAAGSPASLPVLVYFHGGGFCVAMRNKTSQVKIKGMLPIHPFFGSEKRTEKEMANGPEGAVAMNDLFWRLSIPEGSNRDYFGCNLEMQDVSADEWCQFPAVVVFVAGLDFLKERGEMYAEFLQKKGVKEVKLIEEEGESHVFFVFHPKSQATRLLQQQMSKFIKSH
>Yangtao2009909
MGSNNQEIAIDVFPWLQVYKDGTINRLAGTEVVPAGLDPETGVFSKDIVIIPETGVSARLYRHNSRKDGEKKLPLVVYFHGGAFLIASTGEPKYHTSLNKLVAKANVIVASIDYRLAPEHPLPTAYDDSWGAIQWVAAHKGDGGHEPWLKDDVDFDQVFLAGDSAGASIAHHLLTKGLQLKISALRGLQFNISGIAMILPYFWGKEPIGAEVNDPFRREMVNKWWSFVCQSDKGNDDPLINPFVEGSPSLKVLPCDRVFVAVAGSDILRDRGWLYYDQLVKSEWQGKAEIMEIEGEDHVFHIIKPDSEKAKSLIKRWSSFINKGKESSSCV
>Yangtao2019070
MDSTTKEILKELPALIKLYKDGSVERLFCSPNVPSSIDQETGVTSKDITISQDPLVSARLYLPKLVDQSPQKLPILVYFHGGGFCLGSAFTFIEHRYLNKTVSQAQVLAVSIEYRLAPEHPLPAAYEDSWSALQWVASHSVNNSNEVVDKDEWLLNYADFDRLYIGGDSAGANIVHNIAIRAGIETLKCGVKILGAFLSHPFFWGSEAVGRETSANRERDWAYLTWDLVYPSAENGIDNFMINPAGSEAKSLALLALSRLLICVAEQDVFRDRGVWYCDLVKESGWRGEMELFEVKGEGHVFHVLNPQTENAESMFKRLAAFMQ
>Yangtao2019069
MATKTRENPETESVLSKDISISEAPQISARLYLPKLAQPNQKLPILVYFHGGGFCIESAFTLFTHRYLNMLVAQAQVSAVSVEYRQAPEHPLPAAYEDCWAALQWVTSHSSTTAQNEHHNAKDPWISNHGDFDRLFIGGDIAGGNIVHNIAMRAGVESLNCNVNILGDFLSHPYFWGSKPVGSESNANLEKKFCRLVWDFVYPLAENGIDNYMINPVGPGAPSLEGLGCSRLLICVAEKDELRDRGVWYCDLVKESGWRGEVELFEVKGEDHAFHLFNPETENAMNMFKRLASFLLN
>Yangtao2019068
MASVTKEVDRECLPFVRVYKDGSVERPSGSPIVPPSLEDPETGVSSKDVTISQDPSISARLYLPKHTKQDQKLPILVYFHGGGFCVESAFSLVETKLMNSLVSEAKVVGISIEYRLAPEHPIPVVYDDCWAGLQWVASHSMHDDGKDKDPWIKNHGDFDRLFSGGDSSGGNIVHNIAMRAGSEDLQGGVKLSGAFLTHPYFWGSKPIGSEKSEGHDQSVPRQVWDFLYPSAPGGIDNPMMNPLVRGAPSLAGLGCRRLLVSVAELDVLKDRGISYYNALKESGWKGEGKLIQVDGEDHAFHILNYGTETSKKLIQRLASFLSK
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University