Enzyme
A cytochrome P-450 (heme-thiolate) protein found in plants. Acts on a number of flavonoids, including the flavanone naringenin and the flavone apigenin. Does not act on 4-coumarate or 4-coumaroyl-CoA.
F3'H
Enzyme
Flavonoid 3'-hydroxylase
Enzyme name
EC:1.14.14.82
Entry
Oxidoreductases;Acting on paired donors, with incorporation or reduction of molecular oxygen;With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
Class
flavonoid,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3'-hydroxylating)
Sysname
a flavonoid + [reduced NADPH---hemoprotein reductase] + O2 = a 3'-hydroxyflavonoid + [oxidized NADPH---hemoprotein reductase] + H2O [RN:R03615]
Reaction
3'-hydroxyflavonoid [CPD:C02790];[oxidized NADPH---hemoprotein reductase] [CPD:C03161];H2O [CPD:C00001]
Product
Species information
Acorus americanus
Species name
Sweetflag (Acorus americanus) is a species of monocot in the family Acoraceae (sweet flag family).
Species info
Gene sequence info
Acorus_americanus.F3_H.fa
Download
>Acora.04G155400.1.v1.1
MSTLLIILSTLILTTLLYLLLRQPTKPSRLPPGPKGWPVLGNLPQLGPKPHQTMAGLARKYGPLIHLKLGSVHAVVASSPATASLFLKTHDANFCNRPPNAGAKHMAYDGQSIAFAPYGPRWRALRKISTSHLLSPKAIDEFRHVRGEEVSRMVAAILKQEAGRIIFHAAQHFGLKKRDEWMQTVRSAEGSGGVDVGKHLNVCTANAMTRASLGRRLFAEGGEGDREATEFKEMVVELTTLAGAFVLGDFIPSLGWLDPQGVIGKMKRVAKRFDGFLDRIVAEHKEKEKKEKKEDDFLSVLLKLREEEGGGGDDGERLTDVEIKALLLDLFVAGTDTSASTAEWALAELVRHPSILRRAQQELDSVVGRDRLVSEPDLARLPFLQAVIKETFRLHPSTPLSLPHMATDDCEINGYHIPSGSTLFVNVWAIARDPDVWADPLEFNPARFLSGGPKAHVDVRGNDFEVIPFGSGRRICAGINLGLRMVQFMTATLVHAFEWAGPDGLDPEKIDMEEAYGLTLQRAVPLRARLTPRLASHVYRAS
>Acora.04G078100.1.v1.1
MADILILTLTLTLTLLSLILLLLFLSNSHKTKLPPGPKPWPILGNLPDFLPHRGRLHRFLSDLSRLHGPLLTLRRGSSPLLVASTPASASAVLRTHDRSLCSRHVPAAFRFPAYTPSTFIWSTTLDERWRSVRSLCKSELFSSKALDAGSAERERLAARMVESVRERAGARVDVREAVVKVVYRMVGEMVLSADVLERAPFLREQVARAMELAVTPNLEDLWPRVFGGLDLQGLRRETAEQLERMYRVWDDMIAERRRAAEDEATKKQDFFAALLRSGFDDAQIKALFSDLFAAGVDTTTASIEWTLSELVKNACAMAQVKQELDAVVGKHNQVRESHLPELAYLNACIKESLRLHPPVPLLLPHQSEEEDCEVMGHVIPKGCGVMVNVWAIGRDPDAWGHTPDEFCPERFIDHHDDCGVDFKGSHFKFLPFGSGRRACVGMPLGHRMIQLVVASLVHNFDWGLPDGGEADQLDMDDWFELTLERKRPLVLIPS
>Acora.06G203300.1.v1.1
MLSIRIIIQKHSSEKRDIVFPINGGKWDFLKKNPPKRKAMETTPFLLVLSTLILSTLLYILTTTKRGGGAASHHRLPPGPKGWPVLGNLPQLGTKPHQTLAALAKTHGPILRLRLGHVEVVVASSPSAAASFLKTHDANFADRPPNTGGTHMAYDRRDLVFAPYGPRWRMLRRLCSLRLFSNKALDEFTHVREDEVLGMARSFSSASGALVNVGKRLSACATDALGRALMGRRVFGEGREGEAEEFKDMVAELMVLAGEFNVGDFVWGLGWLDLQGIVGRMKRLHRRYDGFLDRIIKEHSMDCSDRKEDFLSVLIGLKDVDGEERLDDVEIKALLLNMFSAGTDTSSSTVEWGLAELIRQPDILKKAQQELDSVVGRARLVSESDLGHLPYFQAVVKETFRLHPSTPLSIPHMASEDCYVDDYFIPKGTTLFVNVWAITHDSKVWPDPLKFDPARFFPDGPAKHVDVKGNDFELIPFGAGRRICVGLNLGLRMVQLMLATLVHGFDWAVDGKVDMEEGYGITLQRAVPLSARPTPRLEPHVYDGVKGSASF
>Acora.08G221900.1.v1.1
MPSQVILDFKGRCRIYTTELDEVVGKDQAVEESDIPNLRYFQAAVKETFRLHPGVPLLIPRRTDEACEVLGYHVPKHAIVFVNVWGMARDPKVWPDEPTEFKSERFVGGDVDVKGQEF
>Acora.08G222200.1.v1.1
MENLTNFTTTITTISALVSLLPLLLLLRRLLRPKNWTNSPPGPTGWPVVGYLPRLTDRLHEDLHHLARTYGPLFSLRMGQRPAIVVSSPDVAREVLKHKDLTFSSRTITEAVRCVTYDATSLVFVPYGARWRLLRKILTTELFSTRAIELLQPARKKQVRGLLKMMYSSWQTKTPVNICDSTFVVSANLVSNLVCSKTLFDDTKKEGRELKEMVWEILEVVGAPNVADLIPFLKVLDPQGLKRRVSKVVKKFDDFFESLIDERLEERKRGVKINENGRLDMLDVFLNYRSDKKDDEMREFSRVDIKGMLSDMFVAGTDTSSSTVEWGLAEILCRPRVYKKVIAELDEVVGKDRAVEESDIPNLRYFQAAVKETFRLHPGVPLLIPRRTDEACEVLGYHVPKHAIVFVNVWGMARDPKVWPDEPTEFKPERFVGGNVDVKGQDFELLPFGTGRRSCVGMPLGHRMVHYVLASLLHAFEWEFPREVLEDSSEKVGITLQKAKGLVGVPKPRLAEHVYKE
>Acora.09G019400.1.v1.1
METTLLLVVSTLFISTLLYILISTTSHRRRRLPPGPKGWPILGNLPQLGPKPHQTLATLAKIHGPILHLRLGHVHVVVASSPSTAASFLKTHDANFADRPPNSGGTHVAYNCQDLVFAPYGPRWRMLRKLCSLHLFSTKALDEFRQVREDEVLNMVRSLHGSRVNNLAVNVGKILNMCATNALSRALMGRRVFGEAEAAAEEFKEMVVELMVVAGEFNVGDFVWGLGWLDPQGVVGRMKKLHRRFDGFLDGIIKEHSMDGSDRKRDLLSVLIGLKEKGEGEERLNDVDIKALLLNMFSAGTDTSSSTVEWALAELILHPDILKKAQQELDSVVGQSRLVSESDLAHLPYFHAIVKETFRLHPSTPLSIPHMASDDCHVDDYFIPKGTTLLVNVWAITHDPNIWPNPLEFDPTRFVPDGPAGHMDVKGNDFELIPFGAGRRICAGMGLGLRMVQLMMATLVHGFDWAVDGKVDMEEAYGITLQRAVPLTAWASPRLEAHVYA
MSTLLIILSTLILTTLLYLLLRQPTKPSRLPPGPKGWPVLGNLPQLGPKPHQTMAGLARKYGPLIHLKLGSVHAVVASSPATASLFLKTHDANFCNRPPNAGAKHMAYDGQSIAFAPYGPRWRALRKISTSHLLSPKAIDEFRHVRGEEVSRMVAAILKQEAGRIIFHAAQHFGLKKRDEWMQTVRSAEGSGGVDVGKHLNVCTANAMTRASLGRRLFAEGGEGDREATEFKEMVVELTTLAGAFVLGDFIPSLGWLDPQGVIGKMKRVAKRFDGFLDRIVAEHKEKEKKEKKEDDFLSVLLKLREEEGGGGDDGERLTDVEIKALLLDLFVAGTDTSASTAEWALAELVRHPSILRRAQQELDSVVGRDRLVSEPDLARLPFLQAVIKETFRLHPSTPLSLPHMATDDCEINGYHIPSGSTLFVNVWAIARDPDVWADPLEFNPARFLSGGPKAHVDVRGNDFEVIPFGSGRRICAGINLGLRMVQFMTATLVHAFEWAGPDGLDPEKIDMEEAYGLTLQRAVPLRARLTPRLASHVYRAS
>Acora.04G078100.1.v1.1
MADILILTLTLTLTLLSLILLLLFLSNSHKTKLPPGPKPWPILGNLPDFLPHRGRLHRFLSDLSRLHGPLLTLRRGSSPLLVASTPASASAVLRTHDRSLCSRHVPAAFRFPAYTPSTFIWSTTLDERWRSVRSLCKSELFSSKALDAGSAERERLAARMVESVRERAGARVDVREAVVKVVYRMVGEMVLSADVLERAPFLREQVARAMELAVTPNLEDLWPRVFGGLDLQGLRRETAEQLERMYRVWDDMIAERRRAAEDEATKKQDFFAALLRSGFDDAQIKALFSDLFAAGVDTTTASIEWTLSELVKNACAMAQVKQELDAVVGKHNQVRESHLPELAYLNACIKESLRLHPPVPLLLPHQSEEEDCEVMGHVIPKGCGVMVNVWAIGRDPDAWGHTPDEFCPERFIDHHDDCGVDFKGSHFKFLPFGSGRRACVGMPLGHRMIQLVVASLVHNFDWGLPDGGEADQLDMDDWFELTLERKRPLVLIPS
>Acora.06G203300.1.v1.1
MLSIRIIIQKHSSEKRDIVFPINGGKWDFLKKNPPKRKAMETTPFLLVLSTLILSTLLYILTTTKRGGGAASHHRLPPGPKGWPVLGNLPQLGTKPHQTLAALAKTHGPILRLRLGHVEVVVASSPSAAASFLKTHDANFADRPPNTGGTHMAYDRRDLVFAPYGPRWRMLRRLCSLRLFSNKALDEFTHVREDEVLGMARSFSSASGALVNVGKRLSACATDALGRALMGRRVFGEGREGEAEEFKDMVAELMVLAGEFNVGDFVWGLGWLDLQGIVGRMKRLHRRYDGFLDRIIKEHSMDCSDRKEDFLSVLIGLKDVDGEERLDDVEIKALLLNMFSAGTDTSSSTVEWGLAELIRQPDILKKAQQELDSVVGRARLVSESDLGHLPYFQAVVKETFRLHPSTPLSIPHMASEDCYVDDYFIPKGTTLFVNVWAITHDSKVWPDPLKFDPARFFPDGPAKHVDVKGNDFELIPFGAGRRICVGLNLGLRMVQLMLATLVHGFDWAVDGKVDMEEGYGITLQRAVPLSARPTPRLEPHVYDGVKGSASF
>Acora.08G221900.1.v1.1
MPSQVILDFKGRCRIYTTELDEVVGKDQAVEESDIPNLRYFQAAVKETFRLHPGVPLLIPRRTDEACEVLGYHVPKHAIVFVNVWGMARDPKVWPDEPTEFKSERFVGGDVDVKGQEF
>Acora.08G222200.1.v1.1
MENLTNFTTTITTISALVSLLPLLLLLRRLLRPKNWTNSPPGPTGWPVVGYLPRLTDRLHEDLHHLARTYGPLFSLRMGQRPAIVVSSPDVAREVLKHKDLTFSSRTITEAVRCVTYDATSLVFVPYGARWRLLRKILTTELFSTRAIELLQPARKKQVRGLLKMMYSSWQTKTPVNICDSTFVVSANLVSNLVCSKTLFDDTKKEGRELKEMVWEILEVVGAPNVADLIPFLKVLDPQGLKRRVSKVVKKFDDFFESLIDERLEERKRGVKINENGRLDMLDVFLNYRSDKKDDEMREFSRVDIKGMLSDMFVAGTDTSSSTVEWGLAEILCRPRVYKKVIAELDEVVGKDRAVEESDIPNLRYFQAAVKETFRLHPGVPLLIPRRTDEACEVLGYHVPKHAIVFVNVWGMARDPKVWPDEPTEFKPERFVGGNVDVKGQDFELLPFGTGRRSCVGMPLGHRMVHYVLASLLHAFEWEFPREVLEDSSEKVGITLQKAKGLVGVPKPRLAEHVYKE
>Acora.09G019400.1.v1.1
METTLLLVVSTLFISTLLYILISTTSHRRRRLPPGPKGWPILGNLPQLGPKPHQTLATLAKIHGPILHLRLGHVHVVVASSPSTAASFLKTHDANFADRPPNSGGTHVAYNCQDLVFAPYGPRWRMLRKLCSLHLFSTKALDEFRQVREDEVLNMVRSLHGSRVNNLAVNVGKILNMCATNALSRALMGRRVFGEAEAAAEEFKEMVVELMVVAGEFNVGDFVWGLGWLDPQGVVGRMKKLHRRFDGFLDGIIKEHSMDGSDRKRDLLSVLIGLKEKGEGEERLNDVDIKALLLNMFSAGTDTSSSTVEWALAELILHPDILKKAQQELDSVVGQSRLVSESDLAHLPYFHAIVKETFRLHPSTPLSIPHMASDDCHVDDYFIPKGTTLLVNVWAITHDPNIWPNPLEFDPTRFVPDGPAGHMDVKGNDFELIPFGAGRRICAGMGLGLRMVQLMMATLVHGFDWAVDGKVDMEEAYGITLQRAVPLTAWASPRLEAHVYA
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University