Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Atriplex hortensis
Species name
Atriplex hortensis is a species of eudicot in the family Chenopodiaceae.
Species info
Gene sequence info
Atriplex_hortensis.COMT.fa
Download
>Ah018476.mRNA1
MGSTSTNTQMGEDEACSFAMTVTSGSVPPMVLKAVIELDVLEIIKRAGPGAHLSPAEITAQLPSKNPDAANMLDRMLRLLASYSILSYTLQTRPDGRVERLYGLAPVCQFLTKNEDGVTLGALSLMNQDKVLMESWYHLKDAVLDGGIPFNKAYGMTAFDYHGTDPRFNKVFNNGMSNHSTITMKRILDTYKGFEGLSSLVDVGGGTGATLNMILSKHPTIKGINFDLPHVIEDAPTYNGVEHVGGDMFASVPKGDAIFMKWICHDWSDEHCLKFLKNCYASLPDHGKVIVCEYILPVAPETSLAARTVFHVDAIMLAHNPGGKERTEQEFESLAKGSGFEGFKVACSAYDTKVMEFLKKTA
>Ah018477.mRNA1
MNSYWKLGAPEEEEGFCIAASLLTASITFGVFKAVKDLNVFEVIKKSGPNAPLSAAEIAAKLSTENPGVAAAALGRMLDLLVSQFVLIVTLVNLPDGVVQRRYGLAPACKFLTPNEDGVSLAPSTNVSMCKAMIESSLFLKDAVLESVEPFTKAHGISFYEYVGENAERREEFHEGINFDQPHVIANAPSYPGVEHVGGNIFVNVPKGDAIFLKNYYDALPEDQGKVIIFEGLRPDPEETTSSIAAKAILQLDMVMMATTGGKERTEKEFKALAFAAGFQGFQVVCSAYNAKIIELPKKN
>Ah018896.mRNA1
MSPSIIGSNESQIHPTTEEETSFMAMCLATWSVPSMVFKTVVEMNVLDIIYNTGPKAQLSAEEIVAQLPTSNPNAAVALDRMLRLLASFTILTCTQKNGPNGHPKRFYGLGPVCQFFAKNDDGVSYAAFAYLVHDKIILDTWKHLKDSVLIGGNNPFENSCGMPFYDYTGIDSRLYKVFYDGMDHHSTIVMKKFLDVYKGFEGISSIVDVGGATGLTLKMILSKYPSITKAINFDLPHIIKNAPSIPGVEHVGGDMYDSIPKADAILMKWIFQAGTDEQCVKLLKNCHESLPEEGKVVICDYVVPETPKNSYQAHTGFIWDVLMLTFLDGKIRTKQEYEIIGKEAGFEAFELVCFACDTWVMEYVKKKTVN
>Ah018895.mRNA1
MSSSIIGSNESQIHPTSEEEASCMAMCLATWSVPSMVFKTVLEMNVLDIIYNTGPKAQLSAEEIVAQLPTTNPNAAVALDRMLRLLASFTILTCTQKNGPNGHPKRLYGLGPVCQFLAKNDDEVSYAAFANLMHDKVIMDTWKHLKDSVLIGGNPFEKSYGMPFFDYLGTDSRFYKVFYDGMDHHSTIVMKKFLDVYEGFEGISSIVDVGGATGLTLKMILSKYPSITKAINFDLPHIIRDAPSVPEVEHVGGDMYNSVPKADAVFMKWTFQSGTDEQCVKLLKNCHEALPEGGKVIICEYVVPETPKTSYQAHTAFIWDAIMLTFPDGKARTKLEYETLGKEAGFEGFKLVCFACDTWVMEYVKKKIAN
>Ah018296.mRNA1
MTSSKMQFQNNGRLNDDEEENNANSIFAMSLLNSSITPIVLQAILELEVFEIINKLGNQVSATEIVANLPAKNPEAATMLDRMLRLLASHSILTCTTRSLPGGPGLAVERVYGLAPVCKFLIKDHNGVSLAPLASISNLIIDSSYQLKDSILKGGHPFERAFGVSHYVYNGRNPTINEKFNTAMASHSKITMDKILETYKGFEDLNSLVDVGGGNGATLTKILSKYPNIRGVEHVGGDMFESIPKGDAVFMKWICHAWSDEQCIKFLKNSYEAIPEEGRVIVCEHVLPDEVETSNAAKFSFQLDAVMMVVPNGKERTQKEFQGLAIAAGFKGFRVASSAYDTKVMEFLKNE
>Ah023669.mRNA1
MTSQVINNGYNGYHTTQPTSLDQDEQLAGFAVTLANAAALPMVLKSAFELKILDIILDAGEGACISTPEIAKKIGSKNPNAPVLLDRMLRLLASHSVLTCKIQKGEKGGVQRVYGPAPLCKYLASNDGQGSLGPLLDLHLDKVMMESWFHLNDYIKEGGVPFKRAHGLIQFDYTGTDARFNHVFNQGMAHHTILVMKKLLEKYHGFDDVKVLVDVGGNIGVNVSMIVAKYPHIKGLNYDLPHVIADAPSYPGVEHVGGDMFESVPHADTIFMKWVLHDWSDEHCLKILKKCYEALPKNGKVILVESLIPVLPEDNLESHMVFSLDCHTLVHNQGGKERSKEDFESLFTQSGFSGINVICCAYDTWVMEIFKK
>Ah022763.mRNA1
MGDNDNLATSPVEDEENDEESFGYALQIVDSMAFPMAMNAIIELDVLGIIAKAGPGRQLLSSEIAASLPGVKNPMVAAIMLERMLWLLATYKVVSCTVVEAKDGGVEKRFGLAPVAKHFVKDRDGVSLAPLMSLSQDKKKNMAPSKPTELDIQNHKPLSVDEEEEANYAYGVQIANSCALPMVLNAAIEIGVLQIINDKAGLDGLLPSEIATEVKASNPEAPAMLDRMLRLLSTYSIVGCNTITTVDGGVERRYKPTSMTKVYVPDEDGVSLAPNLKSKLKDAVLEGGIPFNMVHGMHAFEYPGVDARFNEVFNKAMAQSIIFVKKIFKKYKGLENSNVHKLVDVGGGLGHSVAFITSQYPSIKGINFDLPHVIKDAPSCPGVEHIGGDMFESVPEADAIFLKWILHDWSDDHCLTLLKNCYKALPKDGKVIVVEAIVTDEPETTTFARAISQVDLLMMTQNPGGKERSKREFETLAKGAGFTGINFHCSVHGFWLNVQTKNMYTSLNNNGLLGHSNHIEDAKEEEESYAYAAQILNSCVLPMALKATIDLGVLQVINDMSCSKGGLSPAELAAKIQATNPEAPGMLDRMLRVLATYSVVSCTAVPTPDGGVKRRYGPVPVTRWFVPDQDGVSKLKDAVSEGGIPFNMVHGMHAFEYPGVDARFNEVFNKAMAQSIIFVKKIFKKYKGLENSNVHKLVDVGGGLGHSIAFITSQYPSIKGINFDLPHVIKNAPPCPGVEHIGGDMFVSVPEGDAIFLKWILHDWSDEHCLTLLKNCYKALPKNGKVIVVEAIVTDEPETTALARAISQVDVLMMTQHIGGKERSKREFEALAKGAGFTGINFHCPVYSFWLNNIQTKNMYTSLNNGSLDHPNHKEEVKEEEETYAYAAQILNSCVLPMVLNATIDLGVLQVINDVACSEGGLSPAELATKIQATNPEAPVMLDRMLRVLATYSVVGCTAVPNPDGGVKRRYGPAPVTKWFVPDQDGVSKLKEAVLEGGIPFNKVHGMHAFEYPSVDPRFNDIFNKAMYDQTTYTIKKILEKYKGFQNIHQLVDVGGGLGHSIHAITSKYPSIKGINYDLPHVIEHAPSLPGVEHVGGDMFESVPKGDAIFMKWILHDWSDERCLMLLKNCHKALPENGKVIVVETNITDEPETTALARAISQLDVSMMTQNPGGKERTRREFQALAKATGFSTVNSVCYVSNFWVMEFHK
>Ah030701.mRNA1
MSPEKSTTTAVQPEIDETSEARNKARIAIMELANMISIPMALNAVVRLKVPTAIWSSGANTPLTAADIIPLILPNNPHADADNLGRLLRLLTTYGVFSEHRPLAGEYRRRYSLTDVGRTLVVGDGEGLSHGEYVLQHHQDALVRAWTLVDHAVIGPTSKTPFEVANGEPAYDYYGKNDEMNELMQRAMAGVSVPFMKAVVDGGYDGFDGVVKLVDVGGSAGDCLKMIMSVTHVGGDMFKSIPSADAIFMKWVLTTWSDDEIKLIMKNCYEALPAGGKLIACEPVLPDTSDDSHRTRALLSGDIFVMTIYGAKGRHRMAEEYRQLGISAGFPHFRAVHIDYFFTVLEFQK
>Ah029665.mRNA1
MEEEGNIQQAMQLTTAIALPMALKAAIDLGLFEIIQKAGPGARLSPSDITARLAPDSNNHSQTSQMTDRILRLLSSYSVVSCFVVDNDDNGQPQRLYTLAPLSRYFLQSKDGQGSLAPMFNMIHDPFMTNVWYHMKDAILEGEVPLKKAYGKDPKEAVEKDERFASIFFDSLKEFNILFINKILNEYTGFEGLKSVVDVGGGNGSILKAIISKYPGIKGINFDLPSIIEMQPICPGIEHIAGNMFTSIPTGDAIFMKWVIKNLDDEQCLNVLKNCFKVLPDGGKLMVVELVLPDIPDSSISNRSVFQFDVYLTNMNAEGKERTAGEFQALAKAAGFSGIQAMVRAYDVTLLEFHKTASTN
>Ah036352.mRNA1
WILHDWSDEHCLKLLKNCYKTLTEKGKVIIVEAIMTDDAESTYSARAISQIDIHMMTQNPGGKERSREEFKALAKGAGFGNIKFDCCVFNFWVMELYK
>Ah036360.mRNA1
MVMKVTIDMGVLQLIHAQQGQGLSSEEIATMLQILNKDAPSMLDRMLRLLATYSVVRCSLIPNADGGQERRYGPSPMTKFLVPDADSVSLAPLLDLFIDKVFLQSW
MGSTSTNTQMGEDEACSFAMTVTSGSVPPMVLKAVIELDVLEIIKRAGPGAHLSPAEITAQLPSKNPDAANMLDRMLRLLASYSILSYTLQTRPDGRVERLYGLAPVCQFLTKNEDGVTLGALSLMNQDKVLMESWYHLKDAVLDGGIPFNKAYGMTAFDYHGTDPRFNKVFNNGMSNHSTITMKRILDTYKGFEGLSSLVDVGGGTGATLNMILSKHPTIKGINFDLPHVIEDAPTYNGVEHVGGDMFASVPKGDAIFMKWICHDWSDEHCLKFLKNCYASLPDHGKVIVCEYILPVAPETSLAARTVFHVDAIMLAHNPGGKERTEQEFESLAKGSGFEGFKVACSAYDTKVMEFLKKTA
>Ah018477.mRNA1
MNSYWKLGAPEEEEGFCIAASLLTASITFGVFKAVKDLNVFEVIKKSGPNAPLSAAEIAAKLSTENPGVAAAALGRMLDLLVSQFVLIVTLVNLPDGVVQRRYGLAPACKFLTPNEDGVSLAPSTNVSMCKAMIESSLFLKDAVLESVEPFTKAHGISFYEYVGENAERREEFHEGINFDQPHVIANAPSYPGVEHVGGNIFVNVPKGDAIFLKNYYDALPEDQGKVIIFEGLRPDPEETTSSIAAKAILQLDMVMMATTGGKERTEKEFKALAFAAGFQGFQVVCSAYNAKIIELPKKN
>Ah018896.mRNA1
MSPSIIGSNESQIHPTTEEETSFMAMCLATWSVPSMVFKTVVEMNVLDIIYNTGPKAQLSAEEIVAQLPTSNPNAAVALDRMLRLLASFTILTCTQKNGPNGHPKRFYGLGPVCQFFAKNDDGVSYAAFAYLVHDKIILDTWKHLKDSVLIGGNNPFENSCGMPFYDYTGIDSRLYKVFYDGMDHHSTIVMKKFLDVYKGFEGISSIVDVGGATGLTLKMILSKYPSITKAINFDLPHIIKNAPSIPGVEHVGGDMYDSIPKADAILMKWIFQAGTDEQCVKLLKNCHESLPEEGKVVICDYVVPETPKNSYQAHTGFIWDVLMLTFLDGKIRTKQEYEIIGKEAGFEAFELVCFACDTWVMEYVKKKTVN
>Ah018895.mRNA1
MSSSIIGSNESQIHPTSEEEASCMAMCLATWSVPSMVFKTVLEMNVLDIIYNTGPKAQLSAEEIVAQLPTTNPNAAVALDRMLRLLASFTILTCTQKNGPNGHPKRLYGLGPVCQFLAKNDDEVSYAAFANLMHDKVIMDTWKHLKDSVLIGGNPFEKSYGMPFFDYLGTDSRFYKVFYDGMDHHSTIVMKKFLDVYEGFEGISSIVDVGGATGLTLKMILSKYPSITKAINFDLPHIIRDAPSVPEVEHVGGDMYNSVPKADAVFMKWTFQSGTDEQCVKLLKNCHEALPEGGKVIICEYVVPETPKTSYQAHTAFIWDAIMLTFPDGKARTKLEYETLGKEAGFEGFKLVCFACDTWVMEYVKKKIAN
>Ah018296.mRNA1
MTSSKMQFQNNGRLNDDEEENNANSIFAMSLLNSSITPIVLQAILELEVFEIINKLGNQVSATEIVANLPAKNPEAATMLDRMLRLLASHSILTCTTRSLPGGPGLAVERVYGLAPVCKFLIKDHNGVSLAPLASISNLIIDSSYQLKDSILKGGHPFERAFGVSHYVYNGRNPTINEKFNTAMASHSKITMDKILETYKGFEDLNSLVDVGGGNGATLTKILSKYPNIRGVEHVGGDMFESIPKGDAVFMKWICHAWSDEQCIKFLKNSYEAIPEEGRVIVCEHVLPDEVETSNAAKFSFQLDAVMMVVPNGKERTQKEFQGLAIAAGFKGFRVASSAYDTKVMEFLKNE
>Ah023669.mRNA1
MTSQVINNGYNGYHTTQPTSLDQDEQLAGFAVTLANAAALPMVLKSAFELKILDIILDAGEGACISTPEIAKKIGSKNPNAPVLLDRMLRLLASHSVLTCKIQKGEKGGVQRVYGPAPLCKYLASNDGQGSLGPLLDLHLDKVMMESWFHLNDYIKEGGVPFKRAHGLIQFDYTGTDARFNHVFNQGMAHHTILVMKKLLEKYHGFDDVKVLVDVGGNIGVNVSMIVAKYPHIKGLNYDLPHVIADAPSYPGVEHVGGDMFESVPHADTIFMKWVLHDWSDEHCLKILKKCYEALPKNGKVILVESLIPVLPEDNLESHMVFSLDCHTLVHNQGGKERSKEDFESLFTQSGFSGINVICCAYDTWVMEIFKK
>Ah022763.mRNA1
MGDNDNLATSPVEDEENDEESFGYALQIVDSMAFPMAMNAIIELDVLGIIAKAGPGRQLLSSEIAASLPGVKNPMVAAIMLERMLWLLATYKVVSCTVVEAKDGGVEKRFGLAPVAKHFVKDRDGVSLAPLMSLSQDKKKNMAPSKPTELDIQNHKPLSVDEEEEANYAYGVQIANSCALPMVLNAAIEIGVLQIINDKAGLDGLLPSEIATEVKASNPEAPAMLDRMLRLLSTYSIVGCNTITTVDGGVERRYKPTSMTKVYVPDEDGVSLAPNLKSKLKDAVLEGGIPFNMVHGMHAFEYPGVDARFNEVFNKAMAQSIIFVKKIFKKYKGLENSNVHKLVDVGGGLGHSVAFITSQYPSIKGINFDLPHVIKDAPSCPGVEHIGGDMFESVPEADAIFLKWILHDWSDDHCLTLLKNCYKALPKDGKVIVVEAIVTDEPETTTFARAISQVDLLMMTQNPGGKERSKREFETLAKGAGFTGINFHCSVHGFWLNVQTKNMYTSLNNNGLLGHSNHIEDAKEEEESYAYAAQILNSCVLPMALKATIDLGVLQVINDMSCSKGGLSPAELAAKIQATNPEAPGMLDRMLRVLATYSVVSCTAVPTPDGGVKRRYGPVPVTRWFVPDQDGVSKLKDAVSEGGIPFNMVHGMHAFEYPGVDARFNEVFNKAMAQSIIFVKKIFKKYKGLENSNVHKLVDVGGGLGHSIAFITSQYPSIKGINFDLPHVIKNAPPCPGVEHIGGDMFVSVPEGDAIFLKWILHDWSDEHCLTLLKNCYKALPKNGKVIVVEAIVTDEPETTALARAISQVDVLMMTQHIGGKERSKREFEALAKGAGFTGINFHCPVYSFWLNNIQTKNMYTSLNNGSLDHPNHKEEVKEEEETYAYAAQILNSCVLPMVLNATIDLGVLQVINDVACSEGGLSPAELATKIQATNPEAPVMLDRMLRVLATYSVVGCTAVPNPDGGVKRRYGPAPVTKWFVPDQDGVSKLKEAVLEGGIPFNKVHGMHAFEYPSVDPRFNDIFNKAMYDQTTYTIKKILEKYKGFQNIHQLVDVGGGLGHSIHAITSKYPSIKGINYDLPHVIEHAPSLPGVEHVGGDMFESVPKGDAIFMKWILHDWSDERCLMLLKNCHKALPENGKVIVVETNITDEPETTALARAISQLDVSMMTQNPGGKERTRREFQALAKATGFSTVNSVCYVSNFWVMEFHK
>Ah030701.mRNA1
MSPEKSTTTAVQPEIDETSEARNKARIAIMELANMISIPMALNAVVRLKVPTAIWSSGANTPLTAADIIPLILPNNPHADADNLGRLLRLLTTYGVFSEHRPLAGEYRRRYSLTDVGRTLVVGDGEGLSHGEYVLQHHQDALVRAWTLVDHAVIGPTSKTPFEVANGEPAYDYYGKNDEMNELMQRAMAGVSVPFMKAVVDGGYDGFDGVVKLVDVGGSAGDCLKMIMSVTHVGGDMFKSIPSADAIFMKWVLTTWSDDEIKLIMKNCYEALPAGGKLIACEPVLPDTSDDSHRTRALLSGDIFVMTIYGAKGRHRMAEEYRQLGISAGFPHFRAVHIDYFFTVLEFQK
>Ah029665.mRNA1
MEEEGNIQQAMQLTTAIALPMALKAAIDLGLFEIIQKAGPGARLSPSDITARLAPDSNNHSQTSQMTDRILRLLSSYSVVSCFVVDNDDNGQPQRLYTLAPLSRYFLQSKDGQGSLAPMFNMIHDPFMTNVWYHMKDAILEGEVPLKKAYGKDPKEAVEKDERFASIFFDSLKEFNILFINKILNEYTGFEGLKSVVDVGGGNGSILKAIISKYPGIKGINFDLPSIIEMQPICPGIEHIAGNMFTSIPTGDAIFMKWVIKNLDDEQCLNVLKNCFKVLPDGGKLMVVELVLPDIPDSSISNRSVFQFDVYLTNMNAEGKERTAGEFQALAKAAGFSGIQAMVRAYDVTLLEFHKTASTN
>Ah036352.mRNA1
WILHDWSDEHCLKLLKNCYKTLTEKGKVIIVEAIMTDDAESTYSARAISQIDIHMMTQNPGGKERSREEFKALAKGAGFGNIKFDCCVFNFWVMELYK
>Ah036360.mRNA1
MVMKVTIDMGVLQLIHAQQGQGLSSEEIATMLQILNKDAPSMLDRMLRLLATYSVVRCSLIPNADGGQERRYGPSPMTKFLVPDADSVSLAPLLDLFIDKVFLQSW
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University