Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Acorus americanus
Species name
Sweetflag (Acorus americanus) is a species of monocot in the family Acoraceae (sweet flag family).
Species info
Gene sequence info
Acorus_americanus.CHS.fa
Download
>Acora.01G201900.1.v1.1
MVSVEEIRKAQRAEGPATIMAIGTATPPNAVDQSTYPDYYFRITNSEHKAELKEKFRRMCEKSMIKKRYMHLTEEILKQNPSICEYMAPSLDARQDLVVVEVPKLGKEAATRAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRIAKDLAENTRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGSGALIIGADPIEGVERPIFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGIISKNIEKSLVEAFAPIGISDWNSLFWIAHPGGPAILDQVEEKLGLKEEKLRATRQVLSDYGNMSSACVLFILDEMRRKSKESNAATTGEGLEWGVLFGFGPGLTVETVVLHSVAAV
>Acora.03G203400.1.v1.1
MSTISIEDFRHAQRSDGPATVLAIGTAVPPNMILQSEYPDWYFRVTKSQHKTHLKERLKKMCEKTVVRKRHFYLTEEMLEANPSLIERGAPSLDARQDLVVDEVPRLGMEAAVKAIKEWGEPKSKITHLVFCAAAGIDMPGSDYKLMRLLGLNHNVRRVMIYQQGCFAGAASLRIAKDLAENNRGARVLVVCVEITAMTFAGPSDTHFDTLIGQSLLSDGAASIIVGADPDAETEHPLFQVVSASTTIIPESHGAIDGHIREQGVKFDLMKEVPMFVSKNVERVLVEAFKPIGVTDWNSIFWVTHPGGPYILGAIEKEVGLKEGKLRTAWHVLKEYGNMSSVCVYFVLDEMRRRSAKEGKATTGDGLHWGVLFGFGPGMTIECLTLHSVPIVLDA
>Acora.03G203000.1.v1.1
MSTISIEDFRHAQRSDGPATVLAIGTAVPPNMILQSEYPDWYFRVTKSQHKTHLKERLKKMCEKTAVRKRHFYLTEEMLEANPSLIEHGAPSLDARQDLVVDEVPRLGLEAAVKAIKEWGQPKSKITHLVFCAAAGIDMPGSDYKLMRLLGLNHNVRRVMIYQQGCFAGAASLRIAKDLAENNRGARVLVVCVEITAMTFAGPSDTHFDTLIGQSLLSDGAASIIVGADPDAETEHPLFQVVSASTTIIPESHGAIDGHIREQGVKFDLMKEVPMFVSKNVERVLVEAFKPIGITDWNSIFWVTHPGGPYILGAIEKEVGLKEGKLRTAWHVLKEYGNMSSVCVYFVLDEMRRRSAEEGKATTGDGLDWGVLFGFGPGMTIECLTLHSVPIASDY
>Acora.03G203100.1.v1.1
MREGGLTFHLVKDVPKLISGCIKGQLEEALGPLGVHDWNSIFWVAHPGGRLILDKVEELIGLKEERLRVTRDVLREYGNMSSACVLFIMDEMRRRSAAEGKGTTGEGLELGVLFGFGPGLTVETVVLRSFPTV
>Acora.03G203200.1.v1.1
MSTISIEDFRHAQRSDGPATVLAIGTAVPPNMILQSEYPDWYFRVTKSQHKTHLKERLKKMCEKTAVRKRHFYLTEEMLEANPSLIEHGAPSLDARQDLVVDEVPRLGLEAAVKAIKEWGQPKSKITHLVFCAAAGIDMPGSDYKLMRLLGLNHNVRRVMIYQQGCFAGAASLRIAKDLAENNRGARVLVVCVEITAMTFAGPSDTHFDTLIGQSLLSDGAASIIVGADPDAETEHPLFQVVSASTTIIPESHGAIDGHIREQGVKFDLMKEVPMFVSKNVERVLVEAFKPIGITDWNSIFWVTHPGGPYILGAIEKEVGLKEGKLRTAWHVLKEYGNMSSVCVYFVLDEMRRRSAEEGKATTGDGLDWGVLFGFGPGMTIECLTLHSVPIASDY
>Acora.03G202900.1.v1.1
MHLTEEMLLAHPNIYDDSGPSMDARQDIVVDAVPRLGQAAAAKAIKEWGHPKSSITHLVFHSICGVDIPGSDYKLTRLLGLPNTVKRVMLYQQGCFAGGTVLRVAKDLAENNRGARVLVVCAEVFAMVFNGPSEARLDGLVGQALFGDGAAALVVGADPDPETERPLFQIVSAASKVVPESDGAIEVEELIGLKEERLRVTRDVLREYGNMSSACVLFIMDEMRRRSAAEGKGTTGEGLELGVLFGFGPGLTVETVVLRSFPTV
>Acora.03G203300.1.v1.1
MTKTVDEIWRAQRADSPATVLAIGTAVPPNVYHQSEYPDWYFRVTKSEHKTKLKQKFKRMCEGTTIEKRYMHLTEEMLLAHPNIYDDSGPSMDARQDIVVDAVPRLGQAAAAKAIKEWGHPKSSITHLVFHSICGLDMPGSDYKLTRLLGLPNTVKRVMLYQQGCFAGGTVLRVAKDLAENNRGARVLVVCAEVFAMVFNGPSEARLDGLVGQALFGDGAAALIVGADPDPETERPLFQIVSAASKVVPESDGAIQGHMREGGLTFHLVKDVPKLISGCIKGQLEEALGPLGVHDWNSIFWVAHPGGRLILDKVEELIGLKEERLRVTRDVLREYGNMSSACVLFIMDEMRRRSAAEGKGTTGEGLELGVLFGFGPGLTVETVVLRSFPTV
>Acora.08G035600.1.v1.1
MSGANTNGTTHNNGGNHVSTKRTSTPGKAAVLALGKAFPDNLLLQEQLVEGYFGDTKCEDATMKQKLERLCKTTTVKTRYTVMSKELLSKYPDLAKEGSPTIKQRLEIANQAVLDMATKASLACIADWGRPAAHITHVVYVSSSEIRFPGGDLHLSARLGLTKNVGRVTLYLLGCHGGVAGLRVAKDIAENNKGSRVLLVTSETTVLGYRPPNPSRPYDLVGAALFGDGAAAVVVGADPIEETEFGFMELNHAEQWFVPGTEGVVEGTLTEEGICFRLGRDLPEKIEENVEGFCRSLMEGRVEEGFDGLFWVVHPGGPAILNGVERRLGLGLGKLEWSRRALRDYGNVSSNTVFYVMDYMREVMRRGEGGGGEEWGMVLAFGPGITFEGILVRRLC
>Acora.10G154400.1.v1.1
MVSVDEIRKSQRAEGPATIMAIGTATPPNAVDQSTYPDYYFRITHSEHKADLKEKFRRMCEKSMIKKRYMYLTEEILKQNPSVCAYMAPSLDARQDMVVVEVPKLGKEAATRAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRIAKDLAENNRGARVLVVCSEITAVTFRGPSESHLDSLVGQALFGDGAGALIVGADPVEGIERPIFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGIISKNIEKSLVEAFAPIGIEDWNSLFWVAHPGGPAILDQVEEKLALKEEKLRATRQVLSDYGNMSSACVLFILDEMRRKSLEANAGTTGEGLEWGVLFGFGPGLTVETVVLHSVAV
>Acora.12G041000.1.v1.1
MSSISIEELRRAQRSDGPATILGIGTAVPPNVIPQSEYTDWYFRVTKSEHKTALKAKFKKMCDNSMVRKRHFYLTEEMLEKNPSLIEFGAPSLNARQALVMDEVPRLGMEAAEKAIKEWGQPKSRITHLVFAAAAGIDMPGADYKLLRLMGLNHDVKRVMIYQQGCFAGAQTLRIAKDIAENNRGARVLVVCVEITAMLFAAPDETHLDTFQSQSLLGDGASSVIVGADPDSSERALFQVITASTTIIPESHGAIDGHLREQGVVFDLRREVPLFVSKNVERVLAKAFKPLGISDWNSIFWVTHPGGPYILSSIEKEVGLNEGKLRTAWHVLKEYGNMSSVCVYFILDEMRKRSVAEGKTTTGDGLDWGVLFGFGPGMTIECLTLHSVPVANN
>Acora.12G044200.1.v1.1
MSMTIDEIRRAERADGPASILSMGTVVPPNVYHQAEFPDWYFCITKNEHMTKLKQKIKHKSDRDGSMIDKRCMHVTEEMLNAHPNMCDDTAPSLNVRQDLAVETVPRLGTEAVLLRLLDLPHDTRRVMLYQQGCFAGGTVLRVAKDFAENNRGARVLVVCVDIFAVIFNQPNEARLDGLVGQELVGDDTAAMIIGSDDSEGAIPGKVREVGLTFHLVKDVPGLIPGCIERLLEEAFGGLGVKDWNSVFWVAHPGGRLILDKVGSRKVLREYGNMSSACVLFILDEMRRTSKKEGKGTTGEGLEFGVLFGFGPRLTVETVVLHSCPIV
>Acora.12G040900.1.v1.1
MSMTIDEIRQAQRADGPASILAMGTAVPPNVYHQAEFPDWYFRVTKSEHMTKLKQKFKRMCDGSMIDKRYMHVTEEMLKENPSMCDDTAPSLNVRQDMVVEAVPRLGAEAAVKAIAEWGRPKSEITHLIFHTTCGIDMPGADYKLLRLLDLPHDTRRVMLYQQGCFAGGTVLRIAKDLAENNRGARVLVVCAEIFAVIFNQPNETRLDGLVGQALFGDGAAAMIIGSDVEPDVERPLFQIVSTASNIVQDSEGALLGKVREVGLTLHLVKDVPGLISGSIERLLEEAFGGLGVKDWNSVFWAAHPGGRLILDKVEEKCGLKEERMRATRKVLREYGNMSSACVLFILDEIRRTSEKEGKGTTGEGLEFGVLFGFGPGLTVETVVLRSCPIV
MVSVEEIRKAQRAEGPATIMAIGTATPPNAVDQSTYPDYYFRITNSEHKAELKEKFRRMCEKSMIKKRYMHLTEEILKQNPSICEYMAPSLDARQDLVVVEVPKLGKEAATRAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRIAKDLAENTRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGSGALIIGADPIEGVERPIFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGIISKNIEKSLVEAFAPIGISDWNSLFWIAHPGGPAILDQVEEKLGLKEEKLRATRQVLSDYGNMSSACVLFILDEMRRKSKESNAATTGEGLEWGVLFGFGPGLTVETVVLHSVAAV
>Acora.03G203400.1.v1.1
MSTISIEDFRHAQRSDGPATVLAIGTAVPPNMILQSEYPDWYFRVTKSQHKTHLKERLKKMCEKTVVRKRHFYLTEEMLEANPSLIERGAPSLDARQDLVVDEVPRLGMEAAVKAIKEWGEPKSKITHLVFCAAAGIDMPGSDYKLMRLLGLNHNVRRVMIYQQGCFAGAASLRIAKDLAENNRGARVLVVCVEITAMTFAGPSDTHFDTLIGQSLLSDGAASIIVGADPDAETEHPLFQVVSASTTIIPESHGAIDGHIREQGVKFDLMKEVPMFVSKNVERVLVEAFKPIGVTDWNSIFWVTHPGGPYILGAIEKEVGLKEGKLRTAWHVLKEYGNMSSVCVYFVLDEMRRRSAKEGKATTGDGLHWGVLFGFGPGMTIECLTLHSVPIVLDA
>Acora.03G203000.1.v1.1
MSTISIEDFRHAQRSDGPATVLAIGTAVPPNMILQSEYPDWYFRVTKSQHKTHLKERLKKMCEKTAVRKRHFYLTEEMLEANPSLIEHGAPSLDARQDLVVDEVPRLGLEAAVKAIKEWGQPKSKITHLVFCAAAGIDMPGSDYKLMRLLGLNHNVRRVMIYQQGCFAGAASLRIAKDLAENNRGARVLVVCVEITAMTFAGPSDTHFDTLIGQSLLSDGAASIIVGADPDAETEHPLFQVVSASTTIIPESHGAIDGHIREQGVKFDLMKEVPMFVSKNVERVLVEAFKPIGITDWNSIFWVTHPGGPYILGAIEKEVGLKEGKLRTAWHVLKEYGNMSSVCVYFVLDEMRRRSAEEGKATTGDGLDWGVLFGFGPGMTIECLTLHSVPIASDY
>Acora.03G203100.1.v1.1
MREGGLTFHLVKDVPKLISGCIKGQLEEALGPLGVHDWNSIFWVAHPGGRLILDKVEELIGLKEERLRVTRDVLREYGNMSSACVLFIMDEMRRRSAAEGKGTTGEGLELGVLFGFGPGLTVETVVLRSFPTV
>Acora.03G203200.1.v1.1
MSTISIEDFRHAQRSDGPATVLAIGTAVPPNMILQSEYPDWYFRVTKSQHKTHLKERLKKMCEKTAVRKRHFYLTEEMLEANPSLIEHGAPSLDARQDLVVDEVPRLGLEAAVKAIKEWGQPKSKITHLVFCAAAGIDMPGSDYKLMRLLGLNHNVRRVMIYQQGCFAGAASLRIAKDLAENNRGARVLVVCVEITAMTFAGPSDTHFDTLIGQSLLSDGAASIIVGADPDAETEHPLFQVVSASTTIIPESHGAIDGHIREQGVKFDLMKEVPMFVSKNVERVLVEAFKPIGITDWNSIFWVTHPGGPYILGAIEKEVGLKEGKLRTAWHVLKEYGNMSSVCVYFVLDEMRRRSAEEGKATTGDGLDWGVLFGFGPGMTIECLTLHSVPIASDY
>Acora.03G202900.1.v1.1
MHLTEEMLLAHPNIYDDSGPSMDARQDIVVDAVPRLGQAAAAKAIKEWGHPKSSITHLVFHSICGVDIPGSDYKLTRLLGLPNTVKRVMLYQQGCFAGGTVLRVAKDLAENNRGARVLVVCAEVFAMVFNGPSEARLDGLVGQALFGDGAAALVVGADPDPETERPLFQIVSAASKVVPESDGAIEVEELIGLKEERLRVTRDVLREYGNMSSACVLFIMDEMRRRSAAEGKGTTGEGLELGVLFGFGPGLTVETVVLRSFPTV
>Acora.03G203300.1.v1.1
MTKTVDEIWRAQRADSPATVLAIGTAVPPNVYHQSEYPDWYFRVTKSEHKTKLKQKFKRMCEGTTIEKRYMHLTEEMLLAHPNIYDDSGPSMDARQDIVVDAVPRLGQAAAAKAIKEWGHPKSSITHLVFHSICGLDMPGSDYKLTRLLGLPNTVKRVMLYQQGCFAGGTVLRVAKDLAENNRGARVLVVCAEVFAMVFNGPSEARLDGLVGQALFGDGAAALIVGADPDPETERPLFQIVSAASKVVPESDGAIQGHMREGGLTFHLVKDVPKLISGCIKGQLEEALGPLGVHDWNSIFWVAHPGGRLILDKVEELIGLKEERLRVTRDVLREYGNMSSACVLFIMDEMRRRSAAEGKGTTGEGLELGVLFGFGPGLTVETVVLRSFPTV
>Acora.08G035600.1.v1.1
MSGANTNGTTHNNGGNHVSTKRTSTPGKAAVLALGKAFPDNLLLQEQLVEGYFGDTKCEDATMKQKLERLCKTTTVKTRYTVMSKELLSKYPDLAKEGSPTIKQRLEIANQAVLDMATKASLACIADWGRPAAHITHVVYVSSSEIRFPGGDLHLSARLGLTKNVGRVTLYLLGCHGGVAGLRVAKDIAENNKGSRVLLVTSETTVLGYRPPNPSRPYDLVGAALFGDGAAAVVVGADPIEETEFGFMELNHAEQWFVPGTEGVVEGTLTEEGICFRLGRDLPEKIEENVEGFCRSLMEGRVEEGFDGLFWVVHPGGPAILNGVERRLGLGLGKLEWSRRALRDYGNVSSNTVFYVMDYMREVMRRGEGGGGEEWGMVLAFGPGITFEGILVRRLC
>Acora.10G154400.1.v1.1
MVSVDEIRKSQRAEGPATIMAIGTATPPNAVDQSTYPDYYFRITHSEHKADLKEKFRRMCEKSMIKKRYMYLTEEILKQNPSVCAYMAPSLDARQDMVVVEVPKLGKEAATRAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRIAKDLAENNRGARVLVVCSEITAVTFRGPSESHLDSLVGQALFGDGAGALIVGADPVEGIERPIFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGIISKNIEKSLVEAFAPIGIEDWNSLFWVAHPGGPAILDQVEEKLALKEEKLRATRQVLSDYGNMSSACVLFILDEMRRKSLEANAGTTGEGLEWGVLFGFGPGLTVETVVLHSVAV
>Acora.12G041000.1.v1.1
MSSISIEELRRAQRSDGPATILGIGTAVPPNVIPQSEYTDWYFRVTKSEHKTALKAKFKKMCDNSMVRKRHFYLTEEMLEKNPSLIEFGAPSLNARQALVMDEVPRLGMEAAEKAIKEWGQPKSRITHLVFAAAAGIDMPGADYKLLRLMGLNHDVKRVMIYQQGCFAGAQTLRIAKDIAENNRGARVLVVCVEITAMLFAAPDETHLDTFQSQSLLGDGASSVIVGADPDSSERALFQVITASTTIIPESHGAIDGHLREQGVVFDLRREVPLFVSKNVERVLAKAFKPLGISDWNSIFWVTHPGGPYILSSIEKEVGLNEGKLRTAWHVLKEYGNMSSVCVYFILDEMRKRSVAEGKTTTGDGLDWGVLFGFGPGMTIECLTLHSVPVANN
>Acora.12G044200.1.v1.1
MSMTIDEIRRAERADGPASILSMGTVVPPNVYHQAEFPDWYFCITKNEHMTKLKQKIKHKSDRDGSMIDKRCMHVTEEMLNAHPNMCDDTAPSLNVRQDLAVETVPRLGTEAVLLRLLDLPHDTRRVMLYQQGCFAGGTVLRVAKDFAENNRGARVLVVCVDIFAVIFNQPNEARLDGLVGQELVGDDTAAMIIGSDDSEGAIPGKVREVGLTFHLVKDVPGLIPGCIERLLEEAFGGLGVKDWNSVFWVAHPGGRLILDKVGSRKVLREYGNMSSACVLFILDEMRRTSKKEGKGTTGEGLEFGVLFGFGPRLTVETVVLHSCPIV
>Acora.12G040900.1.v1.1
MSMTIDEIRQAQRADGPASILAMGTAVPPNVYHQAEFPDWYFRVTKSEHMTKLKQKFKRMCDGSMIDKRYMHVTEEMLKENPSMCDDTAPSLNVRQDMVVEAVPRLGAEAAVKAIAEWGRPKSEITHLIFHTTCGIDMPGADYKLLRLLDLPHDTRRVMLYQQGCFAGGTVLRIAKDLAENNRGARVLVVCAEIFAVIFNQPNETRLDGLVGQALFGDGAAAMIIGSDVEPDVERPLFQIVSTASNIVQDSEGALLGKVREVGLTLHLVKDVPGLISGSIERLLEEAFGGLGVKDWNSVFWAAHPGGRLILDKVEEKCGLKEERMRATRKVLREYGNMSSACVLFILDEIRRTSEKEGKGTTGEGLEFGVLFGFGPGLTVETVVLRSCPIV
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University