Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Acorus americanus
Species name
Sweetflag (Acorus americanus) is a species of monocot in the family Acoraceae (sweet flag family).
Species info
Gene sequence info
Acorus_americanus.4CL.fa
Download
>Acora.01G022300.1.v1.1
MAPPHMETSTSPPPSPPPSKDIIFRSKLSDIPIADHLPLHTYCFENLSSLQTHPCLINGSTGETLTYPQVELASRRVAAGLRRLGIRQYDVIMCLLPNSPEFVLTFLAASFLGATITTANPFYTPQETAKQAKACLAKLVVTQSNYVDKVADLGVTIVCVDSEGAPEGCVPFSELASADETELPEVDIKPDDVVALPYSSGTTGLPKGVMLTHRGLVTSVAQQVDGENPNLYFHSEDVILCVLPLFHIYSLNSVLLCGLRAGATILIMSKFEVVALMELVQRYKVTIAPFVPPIVLALAKSPDLDKYDLSSVRTLMSGAAPMGKELEDALRAKIPNAKLGQGYGMTEAGPVLSMCLAFAKEPFEIKSGSCGTVVRNAELKIVDPDTGVSLPRNQAGEICIRGKQIMKGYLNDPEATERTIDKEGWLHTGDIGLVDDDDEIFIVDRLKELIKYKGFQVAPAELEAMLLAHPNIADAAVVPMKDEASGEVPVAFVVRSNGSEITENDIKQYISKQVVFYKRINRVFFIDTIPKAPSGKILRKDLRARLAVGYANGQK
>Acora.01G192600.1.v1.1
MGTYGGDDGIYRSLRPPIGELASHLDLPMLPFLARRAASYPHRLALADADSAETLTFAQLISTVRKLSNSLRRLGIRKGDAVLIVAPNSINYPLIFLSIVSIGAVATTANPAYTVPELSKQAVDSRPRLAVTVNQLYDKVRHLRLPSIILPTPGDDAIPSGDEIIRFADLIATDGPDPPPSDDEEVRSSDVAALLYSSGTTGASKGVVLTHRNFTSAALMVTDDQDRDGDPQNVFLCFLPMFHIFGLSVIAYAQLQRGNLVVSMARFDLDRMLSAVERYRVTHLFVVPPVMIALAKQGKGILRYDLSSLRKLGSGAAPLGKEIMEECVKILPRTQIIQGYGMTETSGIITLEFPEKGERRFGSTGNLVPGVEAKVVSVDTLKPLPPNQLGELWCRGSNVMQGYYNNPQATKLTLDNEGWLHTGDLGYIDEEGQLFVVDRIKELIKYKGYQVAPAELEGLLLSHPEILDAVVIPFPDAEAGEVPIAYVVRSSNSSLTEEDVKKLIAEQVAPFKRLRRVIFVNSVPKSASGKILRRELIEKVRSNL
>Acora.06G002200.1.v1.1
MERPSQLVKEQEEQNVFRSRFPPVPIPDNVTLPDFVLQDAELYSDKPAFMDASTGKTYTHGQVVRDVKRFAKALRALGIRKGHVVLVVLPNVIEYPIIALGVMAAGGVFSGANPLSTPSEIHKQAVDADAKLIVADHSAYDKVKETGIPVIIVGENRAPEGTIAWEDLLTAGDRAGNLPESLNSDALKQDDLCALPYSSGTTGTSKGVMLTHRNLVSNLCSSLFSVGPDMVGQVTALGLMPFFHIYGITGICCATLKCKGKVVVMGRFDIRSFMSALVDHEVNFAPIVPPIMLAMVKNPVVDEFDLGRLKLRSVMTAAAPLAPELLAAFERKFPGVQVQEAYGLTEHSCITLTHGDPRRGHSTAKKNSVGFVLPNLEIKFIDPDTGRSMPRNSPGELCVRSQCVMQGYYRNKEETERAIDGQGWLHTGDVGYIDDDGDVFIVDRIKELIKYKGFQVAPAELEAILLSHPSVEDAAVFGLPDEEAGEVPASCVVMGRGAEEREEEVMKFVASNVASYKRVRVLHFVDTIPKSPSGKIMRRLLRDNMVKRITDKKTSLKP
>Acora.08G012200.1.v1.1
MISLAPQEPQISTISTTLSPPQPQSPPTEHIFRSKLPDIPITNHLPLHSYIFENLSDHADRPCLIVGSTGQILTYSDVHLTIRQTASGLSRRLGLRRGDVVMVLLQNCPEFVYTFMGSSMIGAITTTANPFYTPSELSKQISRSNAKVVVTHSQYAHKVSAEGVPVVTIDDRIDGCLHFSELLEFGLFDPTSMVGGFNPDDAVALPFSSGTTGLPKGVVLTHKSLSTSLSQQVDGENPHVYLTKEDVVICVLPLFHIFALNSVLLCSLRSGAAVLMMQKFEISTLLELIQRYRVSVATVVPPLVLALVKCPMVDEYDLSSIRIVLSGAAPLGKELEETLHGRVPQAIFGQGYGMTEAGPVLSMCLGFAKQPFPTKSGSCGTVVRNAELKVIDPETGYSLPRNKPGEICFRGAQIMKGYLNDPEATKSTIDVEGWLHTGDIGYVDDDDEVFIVDRVKELIKYKGFQVAPAEIEAILHTHPSIIDAAVIPQKDDVAGEVPVAFIVRSNGSELTEASVKEYVAKQVVFYKKVHKVYFVHAIPKSPSGKILRKELRTKLPSS
>Acora.10G026000.1.v1.1
MRRSSTRSTWRRCCTRRDHRVEQWRNIDSHKSIISTSLMATADEVMDGDPHNVFLCFLPMFDVSGLVMIEYTELERGSPVASMVRFTQIQLTWIERRVLWM
MAPPHMETSTSPPPSPPPSKDIIFRSKLSDIPIADHLPLHTYCFENLSSLQTHPCLINGSTGETLTYPQVELASRRVAAGLRRLGIRQYDVIMCLLPNSPEFVLTFLAASFLGATITTANPFYTPQETAKQAKACLAKLVVTQSNYVDKVADLGVTIVCVDSEGAPEGCVPFSELASADETELPEVDIKPDDVVALPYSSGTTGLPKGVMLTHRGLVTSVAQQVDGENPNLYFHSEDVILCVLPLFHIYSLNSVLLCGLRAGATILIMSKFEVVALMELVQRYKVTIAPFVPPIVLALAKSPDLDKYDLSSVRTLMSGAAPMGKELEDALRAKIPNAKLGQGYGMTEAGPVLSMCLAFAKEPFEIKSGSCGTVVRNAELKIVDPDTGVSLPRNQAGEICIRGKQIMKGYLNDPEATERTIDKEGWLHTGDIGLVDDDDEIFIVDRLKELIKYKGFQVAPAELEAMLLAHPNIADAAVVPMKDEASGEVPVAFVVRSNGSEITENDIKQYISKQVVFYKRINRVFFIDTIPKAPSGKILRKDLRARLAVGYANGQK
>Acora.01G192600.1.v1.1
MGTYGGDDGIYRSLRPPIGELASHLDLPMLPFLARRAASYPHRLALADADSAETLTFAQLISTVRKLSNSLRRLGIRKGDAVLIVAPNSINYPLIFLSIVSIGAVATTANPAYTVPELSKQAVDSRPRLAVTVNQLYDKVRHLRLPSIILPTPGDDAIPSGDEIIRFADLIATDGPDPPPSDDEEVRSSDVAALLYSSGTTGASKGVVLTHRNFTSAALMVTDDQDRDGDPQNVFLCFLPMFHIFGLSVIAYAQLQRGNLVVSMARFDLDRMLSAVERYRVTHLFVVPPVMIALAKQGKGILRYDLSSLRKLGSGAAPLGKEIMEECVKILPRTQIIQGYGMTETSGIITLEFPEKGERRFGSTGNLVPGVEAKVVSVDTLKPLPPNQLGELWCRGSNVMQGYYNNPQATKLTLDNEGWLHTGDLGYIDEEGQLFVVDRIKELIKYKGYQVAPAELEGLLLSHPEILDAVVIPFPDAEAGEVPIAYVVRSSNSSLTEEDVKKLIAEQVAPFKRLRRVIFVNSVPKSASGKILRRELIEKVRSNL
>Acora.06G002200.1.v1.1
MERPSQLVKEQEEQNVFRSRFPPVPIPDNVTLPDFVLQDAELYSDKPAFMDASTGKTYTHGQVVRDVKRFAKALRALGIRKGHVVLVVLPNVIEYPIIALGVMAAGGVFSGANPLSTPSEIHKQAVDADAKLIVADHSAYDKVKETGIPVIIVGENRAPEGTIAWEDLLTAGDRAGNLPESLNSDALKQDDLCALPYSSGTTGTSKGVMLTHRNLVSNLCSSLFSVGPDMVGQVTALGLMPFFHIYGITGICCATLKCKGKVVVMGRFDIRSFMSALVDHEVNFAPIVPPIMLAMVKNPVVDEFDLGRLKLRSVMTAAAPLAPELLAAFERKFPGVQVQEAYGLTEHSCITLTHGDPRRGHSTAKKNSVGFVLPNLEIKFIDPDTGRSMPRNSPGELCVRSQCVMQGYYRNKEETERAIDGQGWLHTGDVGYIDDDGDVFIVDRIKELIKYKGFQVAPAELEAILLSHPSVEDAAVFGLPDEEAGEVPASCVVMGRGAEEREEEVMKFVASNVASYKRVRVLHFVDTIPKSPSGKIMRRLLRDNMVKRITDKKTSLKP
>Acora.08G012200.1.v1.1
MISLAPQEPQISTISTTLSPPQPQSPPTEHIFRSKLPDIPITNHLPLHSYIFENLSDHADRPCLIVGSTGQILTYSDVHLTIRQTASGLSRRLGLRRGDVVMVLLQNCPEFVYTFMGSSMIGAITTTANPFYTPSELSKQISRSNAKVVVTHSQYAHKVSAEGVPVVTIDDRIDGCLHFSELLEFGLFDPTSMVGGFNPDDAVALPFSSGTTGLPKGVVLTHKSLSTSLSQQVDGENPHVYLTKEDVVICVLPLFHIFALNSVLLCSLRSGAAVLMMQKFEISTLLELIQRYRVSVATVVPPLVLALVKCPMVDEYDLSSIRIVLSGAAPLGKELEETLHGRVPQAIFGQGYGMTEAGPVLSMCLGFAKQPFPTKSGSCGTVVRNAELKVIDPETGYSLPRNKPGEICFRGAQIMKGYLNDPEATKSTIDVEGWLHTGDIGYVDDDDEVFIVDRVKELIKYKGFQVAPAEIEAILHTHPSIIDAAVIPQKDDVAGEVPVAFIVRSNGSELTEASVKEYVAKQVVFYKKVHKVYFVHAIPKSPSGKILRKELRTKLPSS
>Acora.10G026000.1.v1.1
MRRSSTRSTWRRCCTRRDHRVEQWRNIDSHKSIISTSLMATADEVMDGDPHNVFLCFLPMFDVSGLVMIEYTELERGSPVASMVRFTQIQLTWIERRVLWM
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University