Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Asparagus officinalis
Species name
Garden asparagus (Asparagus officinalis) is a species of monocot in the family Asparagaceae (asparagus family).
Species info
Gene sequence info
Asparagus_officinalis.COMT.fa
Download
>XP_020240977.1
MATTSSSSSDQKEVKKSARLAVMELANMLSVPMALNAVDPPRPSPTSSLDRSTXTPLRTADILCRSFLTPATLLRVLRAAANLQRLLRSSVSHGVFDEHLHGGDLLRRRYSLTEIGKTLVDDEEGNSFAPYVLQHHQDALVKAWPLLHEGILDPTGPDPFTKANGLPAYEFYGKDDEANDLMRRAMAGMSAPFMESFLDGYRRXXXGFDGVGTLVDVGGSSGACLSMIMRRAGNVKVGVNFDLPEVVAGAPEFPGIIHVGGDMFKFIPQGDAIFMKWVLTTWTDEECELILKNCYNALPEGGKVIACEPVVPEETDSSQRTRALLEGDIFVMTVYRALGKERTEDEFRKVGVAAGFTKYRALYLDHFYTVLEFQK
>XP_020241594.1
MGSTQNCITPGPQSTDEEACLYAQQLASFSILPMTLKSAVEXXXXXXDVXTVVTGADGKAERKYGAAPVVKYLTKNEDGVSMAALALMNQDRVLMESWYYLKDAVLDGGIPFNKAYGMTAFEYHGTDQRFNKVFNEGMRNHSTIITKKILETYKGFDGLKTLVDVGGGVGGTLKMILKKHPHIKGINFDLPHVISEAESIPGVEHVGGDMFESVPSGDAIFMKWILHDWSDEHCLKLLKNCWKALPENGKVILMESILPVNPEPTTAAQGVIHVDLIMLAHNPGGKERTENDFDSLAKGAGFSSSKVICGYANSWVLEFYK
>XP_020242046.1
MDPVQNLTTLAPQITTDEDAFIYAHQLVSFSVLPMTLTSAIDLGIFDIIAKAGPGASLSPGEIAAQLPTKNPEAASMLDRMMRLLASYSVLTCTMEARDDGGVERKYGAAPVVKYLAKNEDGVSIAAMAMHQDRVFMESWYYLKDAVLNGGIPFIKAHGMGAFEYLGTDPRVNKAYNEGMKNPSTIITKKILEIYKGFDDLKVLVDVGGGVGGTLKMILQKHPHIKGINIDLPHVISEAEPIPGVEHVTGDIFESVPSGDGILMKWFLHIWSDEDCIKILRNSWKALPEDGKVIIMNNMVPVDPKPTMENQEAIVMDLVLMVKYPGGKERTEMEFHSLAKRAGFSGSEVIYGFANNCMIEFYK
>XP_020242422.1
MGTVQNLTTLAPQITTDEDAFIYAHQLVSFSVLPMTLTSAIDLGIFDIIAKAGPGASLSPGEIAAQLPTKNPEAASMLDRMMRLLASYSVLTCTVEARDDGGVERKYGAAPVVKYLAKNEDGVSIAAMAMHQDRVFMESWYYLKDAVLNGGIPFIKAHGMGAFEYLGTDPRANKVYNEGVKNYSTILTKKILETYKGFDDLKVLVDVGGGVGGTLKMILQKHPHIKGINFDLPHVISEAEPIPGVEHVTGDIFESVPSGDGILMKWFLNIWTDEDCIKILRNCWKALPEDGKVIIMNSMIPVDPKPIMANQEEIFLDLVVMVKYPGGKERTEKEFHSLAKRAGFSSSEVIYGFANNCMIEFYK
>XP_020243634.1
MGSTQNWTTAAPQITTDEEACIYAHQLVSSSILPMTVTSAIDLGIFEIIAKAGPGASLSPVEIAAQLPTENPQAASMLDRMMRLLASYSVLTCTVETRDDGTVERKYGAAPVVKYLTKNEDGVSMAALALNQDRVFIESWYHLKDAVLNGGIPFNKTYGMDLFEYLGTDPRFNQVFNEGMKSHSTIVVKKILETYKGFDNIKVLVDVGGGVGGTLNMILKKHPHIKGINFDLPHVISEAEQIPGVEHVSGDMFDSVPSGDGILMKWNLHMWSDEDCLKILRNCWKALPEDGKVIAMQSIVPDKPEPTMAIQEKIHVDVILMTQFPGGKERTEKEFDTLAKEAGFSRSTVIYGYANCCMIEFHK
>XP_020244003.1
MDPVQNLTTLAPQITTDEDAFIYAHQLVSFSVLPMTLTSAIDLGIFDIIAKAGPGASLSPGEIAAQLPTKNPEAASMLDRMMRLLASYSVLTCTVEARDDGGVERKYGAAPVVKYLAKNEDGVSIAAMALNQDRVFMESWYYLKDAVLNGGIPFIKAHGMGAFEYLGTDPRANKVYNEGVNNYSTILTKKILETYKGFDDLKVLVDVGGGVGGTLKMILQKHSHIKGINIDLPHVISEAEPIPGVEHVTGDIFECVPSGDGILIKWFLNTWSDEDCIQILRNCWKALPEDGKVIIMNSMIPVDPKPIMANQEAILLDLILMAKYPGGKERTENEFHSLAKRAGFSGSEIIYGFANNCMIEFYK
>XP_020244004.1
MDPVQNLTTLAPQITTDEDAFIYAHQLVSFSVLPMTLTSAIDLGIFDIIAKAGPGASLSPGEIAAQLPTKNPEAASMLDRMMRLLASYSVLTCTVEARDDGGVERKYGAAPVVKYLAKNEDGVSIAAMALNQDRVFMESWYYLKDAVLNGGIPFIKAHGMGAFEYLGTDPRANKVYNEGVNNYSTILTKKILETYKGFDDLKVLVDVGGGVGGTLKMILQKHSHIKGINIDLPHVISEAEPIPGVEHVTGDIFECVPSGDGILIKILRNCWKALPEDGKVIIMNSMIPVDPKPIMANQEAILLDLILMAKYPGGKERTENEFHSLAKRAGFSGSEIIYGFANNCMIEFYK
>XP_020253877.1
MAPTFVTSFTQLFGKVKSVVDAAAGLAMISRAVAQTFPEVKVTILDLPHVTEVMDKSEGRIHQYVAGDMFEYIPPADALVLKNCHSLKNCHGLNIHLWDEEEPPTYIVFHILALGSCPEQAFTGYAPAQYYMFYVSVAKYFMKKSGTLSQRG
>XP_020260884.1
MASTYQDDQQYDASADEEMAAFLSAVYIAGAYAVPMTLKAVIELGVLDIIANAGPGRQLSVAEIVSNICTNNAQAATVLDRMLRYLASSSILTCSGTEGAGRVERRYGLSPVGKLFVGVKDGGASLAPLIIMDQHKARQDSCMILLTRQELKHAVLDGVVPFEKVHGMKYFECMRSDPELSRIFNNGMSCTSTLILKIAVGGYPGFKGIQKLVDVGGGTGAALQMIVSKFPQMNGINFDLPHVISHAPPIKGVEHVAGDMFDSIPSGEAVFMKWILHDWSDEDCIKILKNCFEALPDSGKVIIAEFIIPEVPDEDTMTQTMHYADLCMLNFCEGKERTKEEFESLATEAGFSELKLVPSALGIPLIELYK
>XP_020260885.1
MASTYQDDQQYDASADEEMAAFLSAVYIAGAYAVPMTLKAVIELGVLDIIANAGPGRQLSVAEIVSNICTNNAQAATVLDRMLRYLASSSILTCSGTEGAGRVERRYGLSPVGKLFVGVKDGGASLAPLIIMDQHKARQDSWQELKHAVLDGVVPFEKVHGMKYFECMRSDPELSRIFNNGMSCTSTLILKIAVGGYPGFKGIQKLVDVGGGTGAALQMIVSKFPQMNGINFDLPHVISHAPPIKGVEHVAGDMFDSIPSGEAVFMKWILHDWSDEDCIKILKNCFEALPDSGKVIIAEFIIPEVPDEDTMTQTMHYADLCMLNFCEGKERTKEEFESLATEAGFSELKLVPSALGIPLIELYK
>XP_020260886.1
MASTYQDDQQYDASADEEMAAFLSAVYIAGAYAVPMTLKAVIELGVLDIIANAGPGRQLSVAEIVSNICTNNAQAATVLDRMLRYLASSSILTCSGTEGAGRVERRYGLSPVGKLFVGGKDGGASLAPLIIMNMHKARQDSWQEMKYAVLDGVIPFKKINGMHEFEYMKSDHELSKVFNNGMSCASAFILKIVVDSYPGFKGIQKLVDVGGGTGASLQTIISKFPQMNGINFDLPHVISDAPSIKGVEHVAGDMFDSIPSGDAIFMKWILHDWSDKDCLKILKNCLKALPGSGKVIVVDFVIPELPDEDTMTQAMFNTDLCMLNFNEGKERTKDEFESLAKEAGFSELKLVPSAFGIPAIELYK
>XP_020260887.1
MASTYQDDQQYDASADEEMAAFLSAVYIAGAYAVPMTLKAVIELGVLDIIANAGPGRQLSVAEIVSNICTNNAQAATVLDRMLRYLASSSILTCSGTEGAGRVERRYGLSPVGKLFVGGKDGGASLAPLIIMNMHKARQDSWQEMKYAVLDGVIPFKKINGMHEFEYMKSDHELSKVFNNGMSCASAFILKIVVDSYPGFKGIQKLVDVGGGTGASLQTIISKFPQMNGINFDLPHVISDAPSIKGVEHVAGDMFDSIPSGDAIFMKWILHDWSDKDCLKILKNCLKALPGSGKVIVVDFVIPELPDEDTMTQAMFNTDLCMLNFNEGKERTKDEFESLAKEAGFSELKLVPSAFGIPAIELYK
>XP_020262527.1
MAAFLSAVYIAGAYAVPMTLKAVIELGVLDIIANAGPGRQLSVVEIVSNICTNNAQAATVLDRMLRYLASSSILTCSGTEGAGRVERRYGLSPVGKLFAGGKDGGASLAPLIIMNQHKARQASWQELKYAVLDGVIPFKKINGMHEFEYMKSDHELSKVFNDGMSCASAFILKIVVDSYPGFKGIQKLVDVGGGTGASLQTIISKFPQMNGINFDLPHVISDAPPIKGVEHVAGDMFDSIPSGDAVFMKWILHDWSDKDCLKILKNCLKALPGSGKVIVVDFVIPELPDEDTMTQAMFNTDLCMLNFNEGKERTKDEFESLAKEAGFSELKLVPSAFGIPAIELYK
>XP_020266893.1
METLYGRKKSNKSPKYNLLVNQFLIRDTCLLMRYVATQCKGVFKELNILVNVDRAQEPCLCHSKDIPQFKCTVYDLSHVLGSLPENPLINVVGGNTFYHTTTVDANFLMLSNKATNLCFLNTHDTYKMCNKDMLLENRD
MATTSSSSSDQKEVKKSARLAVMELANMLSVPMALNAVDPPRPSPTSSLDRSTXTPLRTADILCRSFLTPATLLRVLRAAANLQRLLRSSVSHGVFDEHLHGGDLLRRRYSLTEIGKTLVDDEEGNSFAPYVLQHHQDALVKAWPLLHEGILDPTGPDPFTKANGLPAYEFYGKDDEANDLMRRAMAGMSAPFMESFLDGYRRXXXGFDGVGTLVDVGGSSGACLSMIMRRAGNVKVGVNFDLPEVVAGAPEFPGIIHVGGDMFKFIPQGDAIFMKWVLTTWTDEECELILKNCYNALPEGGKVIACEPVVPEETDSSQRTRALLEGDIFVMTVYRALGKERTEDEFRKVGVAAGFTKYRALYLDHFYTVLEFQK
>XP_020241594.1
MGSTQNCITPGPQSTDEEACLYAQQLASFSILPMTLKSAVEXXXXXXDVXTVVTGADGKAERKYGAAPVVKYLTKNEDGVSMAALALMNQDRVLMESWYYLKDAVLDGGIPFNKAYGMTAFEYHGTDQRFNKVFNEGMRNHSTIITKKILETYKGFDGLKTLVDVGGGVGGTLKMILKKHPHIKGINFDLPHVISEAESIPGVEHVGGDMFESVPSGDAIFMKWILHDWSDEHCLKLLKNCWKALPENGKVILMESILPVNPEPTTAAQGVIHVDLIMLAHNPGGKERTENDFDSLAKGAGFSSSKVICGYANSWVLEFYK
>XP_020242046.1
MDPVQNLTTLAPQITTDEDAFIYAHQLVSFSVLPMTLTSAIDLGIFDIIAKAGPGASLSPGEIAAQLPTKNPEAASMLDRMMRLLASYSVLTCTMEARDDGGVERKYGAAPVVKYLAKNEDGVSIAAMAMHQDRVFMESWYYLKDAVLNGGIPFIKAHGMGAFEYLGTDPRVNKAYNEGMKNPSTIITKKILEIYKGFDDLKVLVDVGGGVGGTLKMILQKHPHIKGINIDLPHVISEAEPIPGVEHVTGDIFESVPSGDGILMKWFLHIWSDEDCIKILRNSWKALPEDGKVIIMNNMVPVDPKPTMENQEAIVMDLVLMVKYPGGKERTEMEFHSLAKRAGFSGSEVIYGFANNCMIEFYK
>XP_020242422.1
MGTVQNLTTLAPQITTDEDAFIYAHQLVSFSVLPMTLTSAIDLGIFDIIAKAGPGASLSPGEIAAQLPTKNPEAASMLDRMMRLLASYSVLTCTVEARDDGGVERKYGAAPVVKYLAKNEDGVSIAAMAMHQDRVFMESWYYLKDAVLNGGIPFIKAHGMGAFEYLGTDPRANKVYNEGVKNYSTILTKKILETYKGFDDLKVLVDVGGGVGGTLKMILQKHPHIKGINFDLPHVISEAEPIPGVEHVTGDIFESVPSGDGILMKWFLNIWTDEDCIKILRNCWKALPEDGKVIIMNSMIPVDPKPIMANQEEIFLDLVVMVKYPGGKERTEKEFHSLAKRAGFSSSEVIYGFANNCMIEFYK
>XP_020243634.1
MGSTQNWTTAAPQITTDEEACIYAHQLVSSSILPMTVTSAIDLGIFEIIAKAGPGASLSPVEIAAQLPTENPQAASMLDRMMRLLASYSVLTCTVETRDDGTVERKYGAAPVVKYLTKNEDGVSMAALALNQDRVFIESWYHLKDAVLNGGIPFNKTYGMDLFEYLGTDPRFNQVFNEGMKSHSTIVVKKILETYKGFDNIKVLVDVGGGVGGTLNMILKKHPHIKGINFDLPHVISEAEQIPGVEHVSGDMFDSVPSGDGILMKWNLHMWSDEDCLKILRNCWKALPEDGKVIAMQSIVPDKPEPTMAIQEKIHVDVILMTQFPGGKERTEKEFDTLAKEAGFSRSTVIYGYANCCMIEFHK
>XP_020244003.1
MDPVQNLTTLAPQITTDEDAFIYAHQLVSFSVLPMTLTSAIDLGIFDIIAKAGPGASLSPGEIAAQLPTKNPEAASMLDRMMRLLASYSVLTCTVEARDDGGVERKYGAAPVVKYLAKNEDGVSIAAMALNQDRVFMESWYYLKDAVLNGGIPFIKAHGMGAFEYLGTDPRANKVYNEGVNNYSTILTKKILETYKGFDDLKVLVDVGGGVGGTLKMILQKHSHIKGINIDLPHVISEAEPIPGVEHVTGDIFECVPSGDGILIKWFLNTWSDEDCIQILRNCWKALPEDGKVIIMNSMIPVDPKPIMANQEAILLDLILMAKYPGGKERTENEFHSLAKRAGFSGSEIIYGFANNCMIEFYK
>XP_020244004.1
MDPVQNLTTLAPQITTDEDAFIYAHQLVSFSVLPMTLTSAIDLGIFDIIAKAGPGASLSPGEIAAQLPTKNPEAASMLDRMMRLLASYSVLTCTVEARDDGGVERKYGAAPVVKYLAKNEDGVSIAAMALNQDRVFMESWYYLKDAVLNGGIPFIKAHGMGAFEYLGTDPRANKVYNEGVNNYSTILTKKILETYKGFDDLKVLVDVGGGVGGTLKMILQKHSHIKGINIDLPHVISEAEPIPGVEHVTGDIFECVPSGDGILIKILRNCWKALPEDGKVIIMNSMIPVDPKPIMANQEAILLDLILMAKYPGGKERTENEFHSLAKRAGFSGSEIIYGFANNCMIEFYK
>XP_020253877.1
MAPTFVTSFTQLFGKVKSVVDAAAGLAMISRAVAQTFPEVKVTILDLPHVTEVMDKSEGRIHQYVAGDMFEYIPPADALVLKNCHSLKNCHGLNIHLWDEEEPPTYIVFHILALGSCPEQAFTGYAPAQYYMFYVSVAKYFMKKSGTLSQRG
>XP_020260884.1
MASTYQDDQQYDASADEEMAAFLSAVYIAGAYAVPMTLKAVIELGVLDIIANAGPGRQLSVAEIVSNICTNNAQAATVLDRMLRYLASSSILTCSGTEGAGRVERRYGLSPVGKLFVGVKDGGASLAPLIIMDQHKARQDSCMILLTRQELKHAVLDGVVPFEKVHGMKYFECMRSDPELSRIFNNGMSCTSTLILKIAVGGYPGFKGIQKLVDVGGGTGAALQMIVSKFPQMNGINFDLPHVISHAPPIKGVEHVAGDMFDSIPSGEAVFMKWILHDWSDEDCIKILKNCFEALPDSGKVIIAEFIIPEVPDEDTMTQTMHYADLCMLNFCEGKERTKEEFESLATEAGFSELKLVPSALGIPLIELYK
>XP_020260885.1
MASTYQDDQQYDASADEEMAAFLSAVYIAGAYAVPMTLKAVIELGVLDIIANAGPGRQLSVAEIVSNICTNNAQAATVLDRMLRYLASSSILTCSGTEGAGRVERRYGLSPVGKLFVGVKDGGASLAPLIIMDQHKARQDSWQELKHAVLDGVVPFEKVHGMKYFECMRSDPELSRIFNNGMSCTSTLILKIAVGGYPGFKGIQKLVDVGGGTGAALQMIVSKFPQMNGINFDLPHVISHAPPIKGVEHVAGDMFDSIPSGEAVFMKWILHDWSDEDCIKILKNCFEALPDSGKVIIAEFIIPEVPDEDTMTQTMHYADLCMLNFCEGKERTKEEFESLATEAGFSELKLVPSALGIPLIELYK
>XP_020260886.1
MASTYQDDQQYDASADEEMAAFLSAVYIAGAYAVPMTLKAVIELGVLDIIANAGPGRQLSVAEIVSNICTNNAQAATVLDRMLRYLASSSILTCSGTEGAGRVERRYGLSPVGKLFVGGKDGGASLAPLIIMNMHKARQDSWQEMKYAVLDGVIPFKKINGMHEFEYMKSDHELSKVFNNGMSCASAFILKIVVDSYPGFKGIQKLVDVGGGTGASLQTIISKFPQMNGINFDLPHVISDAPSIKGVEHVAGDMFDSIPSGDAIFMKWILHDWSDKDCLKILKNCLKALPGSGKVIVVDFVIPELPDEDTMTQAMFNTDLCMLNFNEGKERTKDEFESLAKEAGFSELKLVPSAFGIPAIELYK
>XP_020260887.1
MASTYQDDQQYDASADEEMAAFLSAVYIAGAYAVPMTLKAVIELGVLDIIANAGPGRQLSVAEIVSNICTNNAQAATVLDRMLRYLASSSILTCSGTEGAGRVERRYGLSPVGKLFVGGKDGGASLAPLIIMNMHKARQDSWQEMKYAVLDGVIPFKKINGMHEFEYMKSDHELSKVFNNGMSCASAFILKIVVDSYPGFKGIQKLVDVGGGTGASLQTIISKFPQMNGINFDLPHVISDAPSIKGVEHVAGDMFDSIPSGDAIFMKWILHDWSDKDCLKILKNCLKALPGSGKVIVVDFVIPELPDEDTMTQAMFNTDLCMLNFNEGKERTKDEFESLAKEAGFSELKLVPSAFGIPAIELYK
>XP_020262527.1
MAAFLSAVYIAGAYAVPMTLKAVIELGVLDIIANAGPGRQLSVVEIVSNICTNNAQAATVLDRMLRYLASSSILTCSGTEGAGRVERRYGLSPVGKLFAGGKDGGASLAPLIIMNQHKARQASWQELKYAVLDGVIPFKKINGMHEFEYMKSDHELSKVFNDGMSCASAFILKIVVDSYPGFKGIQKLVDVGGGTGASLQTIISKFPQMNGINFDLPHVISDAPPIKGVEHVAGDMFDSIPSGDAVFMKWILHDWSDKDCLKILKNCLKALPGSGKVIVVDFVIPELPDEDTMTQAMFNTDLCMLNFNEGKERTKDEFESLAKEAGFSELKLVPSAFGIPAIELYK
>XP_020266893.1
METLYGRKKSNKSPKYNLLVNQFLIRDTCLLMRYVATQCKGVFKELNILVNVDRAQEPCLCHSKDIPQFKCTVYDLSHVLGSLPENPLINVVGGNTFYHTTTVDANFLMLSNKATNLCFLNTHDTYKMCNKDMLLENRD
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University