Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Asparagus officinalis
Species name
Garden asparagus (Asparagus officinalis) is a species of monocot in the family Asparagaceae (asparagus family).
Species info
Gene sequence info
Asparagus_officinalis.HIDH.fa
Download
>XP_020242020.1
MDDNSEILTEFVLRVYKDGHVPRLVGTDTLPAGLAPPXGVTSKDVAINSDVSARLYLPKTATXPQKLPILVYIHGGGFMIESPSPFLPPHLNSLVSQANIVAXSPSIRPRPEHRLPAAYDDSWAALQWAVSPDADPWLTQFGDTGRVFVAGDSAGANIAHXVAMRADKSKEGMILIHPYFWGTEPIGSEVARDPKERKFYEDVWKFVNSGGAHADDPMVNVMAENAPSLKGLPCERVMVAVAGKDALVERGRAYYQALKGSGWGGEVELVDIEDVEHCFHLKNPEVDEAMGLIEKMAAFFAK
>XP_020250695.1
MDPRSEIKVDYAPLFRIYNNGRIDRFTGNTKTPAGFDPVTNVTSKDVTVDSTTGVSARLYLPTFLKTRRLPILVYYHGGVFCVESASSPPYHFFLNLLVSRANIVAVSVDYRLAPEHLIPAAYDDSWAALKWALGSGSDAWLRDYGDFERVFLAGDSAGGNITHNMAMRAGAEGIALEGIQLVHPFFWGTERIGSETMLKAGTVKFIANLWTAVTTPDVGPDDPRFNPIAKSSPSLKGLGCRRAMVCVADCDRLAERGRAYCEVLRGSGWKGEVELVESKGEHVFHLKSPEGEEALALLKKMVEFFTRGRGQDFKSNL
>XP_020250706.1
MYIHGGGFFIGSPYEPMYHNYLVSVVAAAVVVAVSIEYRLAPKHLLPSAYDDAFTAFDWILSRADPWLAERGDYERLFVSGGSAGANIAHNLTMKRGVRIEGMILTHPYFWGATPIDGEITIPL
>XP_020255927.1
MASIDEIEFDSRFIRIYKSGLIQRLIPSDFVQPSIDPETRVSSKDTTINPQTSLSARIYLPNLAHSPSSRLPLIIYYHGGAFCLGSAFSSFTHNYLNPLVAQLNVVLVSVGYRLAPEHPIPAAYDDSWEALKWAVAHVNGEGPDDWLSAHADFDRLFLAGDSAGGNIAHNVAMRAGTERVGDGVEIEGSVIIHPYFLEGKKSNSTEDMEKMWRMTCPSTTGLDDHRINPMAQMAPTLRGLGCRRVLVCLGEKDFLRKGGRSYCERLMESGWEGEGEVFETEGEGHAFHVFDVGSEKAIAQTRKISDFINGI
>XP_020255928.1
MASIDEIEFDSRFIRIYKSGLIQRLIPSDFVQPSIDPETRVSSKDTTINPQTSLSARIYLPNLAHSPSSRLPLIIYYHGGAFCLGSAFSSFTHNYLNPLVAQLNVVLVSVGYRLAPEHPIPAAYDDSWEALKWAVAHVNGEGPDDWLSAHADFDRLFLAGDSAGGNIAHNVAMRAGTERVGDGVEIEGSVIIHPYFLEGKKSNSTEDMEKMWRMTCPSTTGLDDHRINPMAQMAPTLTGLGCRRVLVCLGEKDFLRKGGRSYCERLMESGWEGEGEVFETEGEGHAFHVFDVGSEKAIAQTRKISDFINGI
>XP_020255966.1
MIPHSIYISNREERAERKRAEAMEPQTVSEPNPNVHIRIRDEGAKTLATSNQNPNVCWCKRRIGNSFSLFVFALQGPFDKIGNLKDPDESIVRRFKVNSAKLRHQVMYLIRPPGLPWHNPKSTIITMSNTDTTPIEVRRCEVFFKLFSGRSIARSPDPSFPVPIHDDGTVEWKDVEFDPVHKLSLRLYKPRDPNGSRLPIFYYFHGGGFCIGSRTWPNCQNYCLRLASELQAVIISPDYRLAPEHRLPAAIDDSFSAVKWLHAQSAATDPDTWLSNVADFTRVFISGDSAGGTITHHLAISNFADLAPVRIRGYVLLGPFFGGTQRTKSEAECPKDAFLNLELNDRFWRLSMPIGADIDHPLINPFGPESVSLEKVEIEPMLVVVGGCDLLRDRAVEYAERLKEWGKPVEVAEFEGQQHGFFTIDPWSEPANELMEVVKRFVGESGGGCN
>XP_020255967.1
MIPHSIYISNREERAERKRAEAMEPQTVSEPNPNVHIRDEGAKTLATSNQNPNVCWCKRRIGNSFSLFVFALQGPFDKIGNLKDPDESIVRRFKVNSAKLRHQVMYLIRPPGLPWHNPKSTIITMSNTDTTPIEVRRCEVFFKLFSGRSIARSPDPSFPVPIHDDGTVEWKDVEFDPVHKLSLRLYKPRDPNGSRLPIFYYFHGGGFCIGSRTWPNCQNYCLRLASELQAVIISPDYRLAPEHRLPAAIDDSFSAVKWLHAQSAATDPDTWLSNVADFTRVFISGDSAGGTITHHLAISNFADLAPVRIRGYVLLGPFFGGTQRTKSEAECPKDAFLNLELNDRFWRLSMPIGADIDHPLINPFGPESVSLEKVEIEPMLVVVGGCDLLRDRAVEYAERLKEWGKPVEVAEFEGQQHGFFTIDPWSEPANELMEVVKRFVGESGGGCN
>XP_020255969.1
MYLIRPPGLPWHNPKSTIITMSNTDTTPIEVRRCEVFFKLFSGRSIARSPDPSFPVPIHDDGTVEWKDVEFDPVHKLSLRLYKPRDPNGSRLPIFYYFHGGGFCIGSRTWPNCQNYCLRLASELQAVIISPDYRLAPEHRLPAAIDDSFSAVKWLHAQSAATDPDTWLSNVADFTRVFISGDSAGGTITHHLAISNFADLAPVRIRGYVLLGPFFGGTQRTKSEAECPKDAFLNLELNDRFWRLSMPIGADIDHPLINPFGPESVSLEKVEIEPMLVVVGGCDLLRDRAVEYAERLKEWGKPVEVAEFEGQQHGFFTIDPWSEPANELMEVVKRFVGESGGGCN
>XP_020258208.1
MASTDEIEFDSRFIRIYKSGLIQRLIPSDFVQPSIDPETRVSSKDMTINPQTSLSARIYLPNLAHSPSSRLPLIIYYHGGAFCLGSAFSSFTHNYLNPLVAQLNIVLVSVSYRLAPEHPIPAAYDDSWEALKWAAAHVNGEGPDDWLSAHADFDRLFLAGDSAGGNIAHNVAMRAGTERVGDGVEIEGSVMIHPYFLEGKKSNSTEDMEKMWRMTCPSTTGLDDHRINPMAQMAPTLMGLGCRRVLVCLGEDFLREGGRSYCERLMESGWEGEGEVFETKGEGHAFHVFDVGSEKAIAQTRKISDFINGYSNTDWADDPLDQHSISGYCTFVGGNLVTWRSKKQTVVALPSAEAEYKAMAYAPAR
>XP_020260254.1
LGKQMNLAVLGSGRSGDLRRGDSKWRIVDTFGAASVEPWLAAHGDPSRCILLGVSCGANIADYVARKSVEAGKLIDPVKIVAQVLMYPFFIGSVPTHSEIKLANSYFFDKAMCILAWRLFLPEEEFDLDHPAANPLIPNRGPPLKCMPPTLTVVAEHDWMRDRAIAYSEELRKVNVDAPVLEYKDAVHEFATLDMLLKTPQAQACAEDIAIWVKKYISLRGHEFSY
MDDNSEILTEFVLRVYKDGHVPRLVGTDTLPAGLAPPXGVTSKDVAINSDVSARLYLPKTATXPQKLPILVYIHGGGFMIESPSPFLPPHLNSLVSQANIVAXSPSIRPRPEHRLPAAYDDSWAALQWAVSPDADPWLTQFGDTGRVFVAGDSAGANIAHXVAMRADKSKEGMILIHPYFWGTEPIGSEVARDPKERKFYEDVWKFVNSGGAHADDPMVNVMAENAPSLKGLPCERVMVAVAGKDALVERGRAYYQALKGSGWGGEVELVDIEDVEHCFHLKNPEVDEAMGLIEKMAAFFAK
>XP_020250695.1
MDPRSEIKVDYAPLFRIYNNGRIDRFTGNTKTPAGFDPVTNVTSKDVTVDSTTGVSARLYLPTFLKTRRLPILVYYHGGVFCVESASSPPYHFFLNLLVSRANIVAVSVDYRLAPEHLIPAAYDDSWAALKWALGSGSDAWLRDYGDFERVFLAGDSAGGNITHNMAMRAGAEGIALEGIQLVHPFFWGTERIGSETMLKAGTVKFIANLWTAVTTPDVGPDDPRFNPIAKSSPSLKGLGCRRAMVCVADCDRLAERGRAYCEVLRGSGWKGEVELVESKGEHVFHLKSPEGEEALALLKKMVEFFTRGRGQDFKSNL
>XP_020250706.1
MYIHGGGFFIGSPYEPMYHNYLVSVVAAAVVVAVSIEYRLAPKHLLPSAYDDAFTAFDWILSRADPWLAERGDYERLFVSGGSAGANIAHNLTMKRGVRIEGMILTHPYFWGATPIDGEITIPL
>XP_020255927.1
MASIDEIEFDSRFIRIYKSGLIQRLIPSDFVQPSIDPETRVSSKDTTINPQTSLSARIYLPNLAHSPSSRLPLIIYYHGGAFCLGSAFSSFTHNYLNPLVAQLNVVLVSVGYRLAPEHPIPAAYDDSWEALKWAVAHVNGEGPDDWLSAHADFDRLFLAGDSAGGNIAHNVAMRAGTERVGDGVEIEGSVIIHPYFLEGKKSNSTEDMEKMWRMTCPSTTGLDDHRINPMAQMAPTLRGLGCRRVLVCLGEKDFLRKGGRSYCERLMESGWEGEGEVFETEGEGHAFHVFDVGSEKAIAQTRKISDFINGI
>XP_020255928.1
MASIDEIEFDSRFIRIYKSGLIQRLIPSDFVQPSIDPETRVSSKDTTINPQTSLSARIYLPNLAHSPSSRLPLIIYYHGGAFCLGSAFSSFTHNYLNPLVAQLNVVLVSVGYRLAPEHPIPAAYDDSWEALKWAVAHVNGEGPDDWLSAHADFDRLFLAGDSAGGNIAHNVAMRAGTERVGDGVEIEGSVIIHPYFLEGKKSNSTEDMEKMWRMTCPSTTGLDDHRINPMAQMAPTLTGLGCRRVLVCLGEKDFLRKGGRSYCERLMESGWEGEGEVFETEGEGHAFHVFDVGSEKAIAQTRKISDFINGI
>XP_020255966.1
MIPHSIYISNREERAERKRAEAMEPQTVSEPNPNVHIRIRDEGAKTLATSNQNPNVCWCKRRIGNSFSLFVFALQGPFDKIGNLKDPDESIVRRFKVNSAKLRHQVMYLIRPPGLPWHNPKSTIITMSNTDTTPIEVRRCEVFFKLFSGRSIARSPDPSFPVPIHDDGTVEWKDVEFDPVHKLSLRLYKPRDPNGSRLPIFYYFHGGGFCIGSRTWPNCQNYCLRLASELQAVIISPDYRLAPEHRLPAAIDDSFSAVKWLHAQSAATDPDTWLSNVADFTRVFISGDSAGGTITHHLAISNFADLAPVRIRGYVLLGPFFGGTQRTKSEAECPKDAFLNLELNDRFWRLSMPIGADIDHPLINPFGPESVSLEKVEIEPMLVVVGGCDLLRDRAVEYAERLKEWGKPVEVAEFEGQQHGFFTIDPWSEPANELMEVVKRFVGESGGGCN
>XP_020255967.1
MIPHSIYISNREERAERKRAEAMEPQTVSEPNPNVHIRDEGAKTLATSNQNPNVCWCKRRIGNSFSLFVFALQGPFDKIGNLKDPDESIVRRFKVNSAKLRHQVMYLIRPPGLPWHNPKSTIITMSNTDTTPIEVRRCEVFFKLFSGRSIARSPDPSFPVPIHDDGTVEWKDVEFDPVHKLSLRLYKPRDPNGSRLPIFYYFHGGGFCIGSRTWPNCQNYCLRLASELQAVIISPDYRLAPEHRLPAAIDDSFSAVKWLHAQSAATDPDTWLSNVADFTRVFISGDSAGGTITHHLAISNFADLAPVRIRGYVLLGPFFGGTQRTKSEAECPKDAFLNLELNDRFWRLSMPIGADIDHPLINPFGPESVSLEKVEIEPMLVVVGGCDLLRDRAVEYAERLKEWGKPVEVAEFEGQQHGFFTIDPWSEPANELMEVVKRFVGESGGGCN
>XP_020255969.1
MYLIRPPGLPWHNPKSTIITMSNTDTTPIEVRRCEVFFKLFSGRSIARSPDPSFPVPIHDDGTVEWKDVEFDPVHKLSLRLYKPRDPNGSRLPIFYYFHGGGFCIGSRTWPNCQNYCLRLASELQAVIISPDYRLAPEHRLPAAIDDSFSAVKWLHAQSAATDPDTWLSNVADFTRVFISGDSAGGTITHHLAISNFADLAPVRIRGYVLLGPFFGGTQRTKSEAECPKDAFLNLELNDRFWRLSMPIGADIDHPLINPFGPESVSLEKVEIEPMLVVVGGCDLLRDRAVEYAERLKEWGKPVEVAEFEGQQHGFFTIDPWSEPANELMEVVKRFVGESGGGCN
>XP_020258208.1
MASTDEIEFDSRFIRIYKSGLIQRLIPSDFVQPSIDPETRVSSKDMTINPQTSLSARIYLPNLAHSPSSRLPLIIYYHGGAFCLGSAFSSFTHNYLNPLVAQLNIVLVSVSYRLAPEHPIPAAYDDSWEALKWAAAHVNGEGPDDWLSAHADFDRLFLAGDSAGGNIAHNVAMRAGTERVGDGVEIEGSVMIHPYFLEGKKSNSTEDMEKMWRMTCPSTTGLDDHRINPMAQMAPTLMGLGCRRVLVCLGEDFLREGGRSYCERLMESGWEGEGEVFETKGEGHAFHVFDVGSEKAIAQTRKISDFINGYSNTDWADDPLDQHSISGYCTFVGGNLVTWRSKKQTVVALPSAEAEYKAMAYAPAR
>XP_020260254.1
LGKQMNLAVLGSGRSGDLRRGDSKWRIVDTFGAASVEPWLAAHGDPSRCILLGVSCGANIADYVARKSVEAGKLIDPVKIVAQVLMYPFFIGSVPTHSEIKLANSYFFDKAMCILAWRLFLPEEEFDLDHPAANPLIPNRGPPLKCMPPTLTVVAEHDWMRDRAIAYSEELRKVNVDAPVLEYKDAVHEFATLDMLLKTPQAQACAEDIAIWVKKYISLRGHEFSY
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University