Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Asparagus officinalis
Species name
Garden asparagus (Asparagus officinalis) is a species of monocot in the family Asparagaceae (asparagus family).
Species info
Gene sequence info
Asparagus_officinalis.4CL.fa
Download
>XP_020244752.1
MGDLTVQESGQHIFRSKYSTPIRVHENTTLPEFVLRDALEYSDKVALVEASTGKAYTYGEVVRDTARFARALGSLGLRKGHVVAVALPNLAVYPVVALGIMAAGGVFSGVNPSALASEIRKQVEDSEAKIVVADEATYDKVKDFGVPVIVIGETLTPDAVNWKELLEAADRAGHSNAVENNLTQDDLCALPYSSGTTGTSKGVMLTHRNIISNLCSSLFSFGADMIGQVTTLGLMPFFHIYGITGICCAALKTKGKVVVMGRFDLRAYLEILIEHEVTFAPIVPAIILAMVKSPLVDEFDLRRLKLQSVLTAAAPLAPELRAAFEEKYPGVVVQEAYGLTEHSCITLTHGDPRKGHGVAKKNSVGFILPNLEVKFVDPETGKPLPKNTPGEICVRSKCVMQGYYKNKEETERTVDGEGWLHTGDIGYIDDDGDVFIVDRIKELIKYKGFQVAPAELEAILLTHPSVDDVAVFGLPDEDAGELPAACIVMSKSAAETEEDIKSYVASNVASYKRIRVVKFVESIPKSASGKIMRRFLRESVANNRR
>XP_020260662.1
MTEAGPVISMCPGFAKNPTPAKSGSCGTVVRNAELKVLDPDTGLSLGRNQPGEICIRGPQIMKGYLNDPVATSATIDVEGWLHTGDIGYVDDDDEVYIVDRVKELIKFKGFQVPPAELEALLLGHPSIADAAVIPQKDEVAGEVPVAFVVPSKDSDLTEEAIKEFISKQVVFYKRLQRVYFIHSIPKSPSGKILRKDLRAKLSAAS
>XP_020260907.1
MIGLAKQGMVMRRRFDLGSLRWVCSGAAPLGRDVMEEVANSFPEVELVQGYGLTETCSIVSLERPQAWARKFGSTGYLMPGIEAKIISIGTSKTLPPNQNGEILVRGPNIMQGYFKNLEATKFTLDEEGWLHTGDLGYFDEKGQLYVEDRLKELIKCKGFQVAPAELESVLTSHPEILDAAVVPMEDAEAGEVPVAFVVTRNSSLTEVDVQKFVASQVAPFKRLRRVIFENSIPKTASGKILRRELTNTVKTLRRELSDKVRSKL
>XP_020260908.1
SPSSSAASIPSPTARPHRLRLRTTAQTLTFRQLRSAVSSFASALSRLGIRKGDVVLIFAPNSVLFPVSFLSIISLGAIATTVNPLYTVGELKKQALDSGAKLVLTVPDLVPKVSSLNLPIILLAENANKDVSFPTFYDLIKNQSPSEFAPPEINQDDTVALLYSSGTTGASKGVVLTHRNFISVAMMAVQDQDTRGEPPNIFLCFLPMFHIFGLSVITFAQLARGNTVVVMKRFDMEMTLRSIERYRVSYLFVVPPVMIALAKQGKVTKYDLSSLRRLGSGAAPLGKDVMEEVAGIFPQADIVQGYGLTESCGIVSLELPRGASLRQYGSTGNLVSGVEGKVVSVDTLRSLPPNQLGELCFRGPNMMRGYFNNSQASKLTKDKEGWLHTGDLGYFNEEGQLFVVDRIKELIKYKGFQEFDVI
>XP_020262417.1
MPGCMFGAKLVVTQSAYIDRLPKIDDLIVITIDDPMPGCMFFGEINSADENDVPDVSIDPDDAVAMPFSSGTTGLPKGVVLTHPEHLCQAWPQQVDGENPNLWMRAGEDVMLCVLPMFHIFRAELGAAVRDEGGARCDNARFEMERMLEAIER
>XP_020262537.1
SPSAASLSRLGIRKGDVVLIFSPNSLLFPISFLSIVSLGAIATTVNPHYTVPELKQQALDSGTKLVLTVPDLLPKAMYAVPPVMTALAKQGKPTGYDLSSLRRIAAGAAPLGKDVMEEVSEIFPRADIIQGYALTESCGVMSLELPKGAPRQFGSAGHLISGVEGKVVSVDTLKSLPPNQLGELCFRGPNIMRGYFNNPQATELTIDKEGWLHTGDLGYFNEEGQVFIVDRIKELIKYKGFQVAPKMNFGFLLSYPKILDAAVIPFPDAEAGEVPIAFVVRSHNCSLTEFDVQKFIANQVAPFKRLRRVTFVNSIPKSASGKILRRELRERVKSKL
>XP_020264712.1
MTEAGPVLSMCLAFAKEPFDVKSGSCGTVVRNAELKIVDPDTGFSLSRNQPGEICIRGHQIMKGYLNDPESTERTIDKEGWLHTGDIGYVDDDDEIFIVDRLKELIKYKGFQVAPAELEAMLITHPNIADAAVVPMKDDLAGEMPVSFVVRSGGSEITEDEIKQFVSKQVVFYKRIHKVFFVDAIPKAPSGKILRKDLRARLAAGFPNGQQL
MGDLTVQESGQHIFRSKYSTPIRVHENTTLPEFVLRDALEYSDKVALVEASTGKAYTYGEVVRDTARFARALGSLGLRKGHVVAVALPNLAVYPVVALGIMAAGGVFSGVNPSALASEIRKQVEDSEAKIVVADEATYDKVKDFGVPVIVIGETLTPDAVNWKELLEAADRAGHSNAVENNLTQDDLCALPYSSGTTGTSKGVMLTHRNIISNLCSSLFSFGADMIGQVTTLGLMPFFHIYGITGICCAALKTKGKVVVMGRFDLRAYLEILIEHEVTFAPIVPAIILAMVKSPLVDEFDLRRLKLQSVLTAAAPLAPELRAAFEEKYPGVVVQEAYGLTEHSCITLTHGDPRKGHGVAKKNSVGFILPNLEVKFVDPETGKPLPKNTPGEICVRSKCVMQGYYKNKEETERTVDGEGWLHTGDIGYIDDDGDVFIVDRIKELIKYKGFQVAPAELEAILLTHPSVDDVAVFGLPDEDAGELPAACIVMSKSAAETEEDIKSYVASNVASYKRIRVVKFVESIPKSASGKIMRRFLRESVANNRR
>XP_020260662.1
MTEAGPVISMCPGFAKNPTPAKSGSCGTVVRNAELKVLDPDTGLSLGRNQPGEICIRGPQIMKGYLNDPVATSATIDVEGWLHTGDIGYVDDDDEVYIVDRVKELIKFKGFQVPPAELEALLLGHPSIADAAVIPQKDEVAGEVPVAFVVPSKDSDLTEEAIKEFISKQVVFYKRLQRVYFIHSIPKSPSGKILRKDLRAKLSAAS
>XP_020260907.1
MIGLAKQGMVMRRRFDLGSLRWVCSGAAPLGRDVMEEVANSFPEVELVQGYGLTETCSIVSLERPQAWARKFGSTGYLMPGIEAKIISIGTSKTLPPNQNGEILVRGPNIMQGYFKNLEATKFTLDEEGWLHTGDLGYFDEKGQLYVEDRLKELIKCKGFQVAPAELESVLTSHPEILDAAVVPMEDAEAGEVPVAFVVTRNSSLTEVDVQKFVASQVAPFKRLRRVIFENSIPKTASGKILRRELTNTVKTLRRELSDKVRSKL
>XP_020260908.1
SPSSSAASIPSPTARPHRLRLRTTAQTLTFRQLRSAVSSFASALSRLGIRKGDVVLIFAPNSVLFPVSFLSIISLGAIATTVNPLYTVGELKKQALDSGAKLVLTVPDLVPKVSSLNLPIILLAENANKDVSFPTFYDLIKNQSPSEFAPPEINQDDTVALLYSSGTTGASKGVVLTHRNFISVAMMAVQDQDTRGEPPNIFLCFLPMFHIFGLSVITFAQLARGNTVVVMKRFDMEMTLRSIERYRVSYLFVVPPVMIALAKQGKVTKYDLSSLRRLGSGAAPLGKDVMEEVAGIFPQADIVQGYGLTESCGIVSLELPRGASLRQYGSTGNLVSGVEGKVVSVDTLRSLPPNQLGELCFRGPNMMRGYFNNSQASKLTKDKEGWLHTGDLGYFNEEGQLFVVDRIKELIKYKGFQEFDVI
>XP_020262417.1
MPGCMFGAKLVVTQSAYIDRLPKIDDLIVITIDDPMPGCMFFGEINSADENDVPDVSIDPDDAVAMPFSSGTTGLPKGVVLTHPEHLCQAWPQQVDGENPNLWMRAGEDVMLCVLPMFHIFRAELGAAVRDEGGARCDNARFEMERMLEAIER
>XP_020262537.1
SPSAASLSRLGIRKGDVVLIFSPNSLLFPISFLSIVSLGAIATTVNPHYTVPELKQQALDSGTKLVLTVPDLLPKAMYAVPPVMTALAKQGKPTGYDLSSLRRIAAGAAPLGKDVMEEVSEIFPRADIIQGYALTESCGVMSLELPKGAPRQFGSAGHLISGVEGKVVSVDTLKSLPPNQLGELCFRGPNIMRGYFNNPQATELTIDKEGWLHTGDLGYFNEEGQVFIVDRIKELIKYKGFQVAPKMNFGFLLSYPKILDAAVIPFPDAEAGEVPIAFVVRSHNCSLTEFDVQKFIANQVAPFKRLRRVTFVNSIPKSASGKILRRELRERVKSKL
>XP_020264712.1
MTEAGPVLSMCLAFAKEPFDVKSGSCGTVVRNAELKIVDPDTGFSLSRNQPGEICIRGHQIMKGYLNDPESTERTIDKEGWLHTGDIGYVDDDDEIFIVDRLKELIKYKGFQVAPAELEAMLITHPNIADAAVVPMKDDLAGEMPVSFVVRSGGSEITEDEIKQFVSKQVVFYKRIHKVFFVDAIPKAPSGKILRKDLRARLAAGFPNGQQL
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University