Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Aristolochia fimbriata
Species name
Aristolochia fimbriata is a species of flowering plant in the family Aristolochiaceae (birthwort family).
Species info
Gene sequence info
Aristolochia_fimbriata.COMT.fa
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>Af02G353300.1
MGTPASSVLLQALQPWRRLEQIKTPLLASSSAVESRYHLMEETNVGSKAVDLGQLAGLPMALEAAIELNVIEILANSAGRESKLLSSSQIVEQIPARNPKAAAVTLERILRFLASNSVLTSTRNEKGEMLYGLTPVCEYFLPNKDGVSLATLVTFANDKVMMQSWHHLKEAVLTEGSVPPFNIAHDGMNAFEYNARDERFNKLFNDAMFNHSTLVLRQVLENYKEFERLEEIVDVGGGIGASLKMITSRYPHIKGTNFDLPHVIAEAPPCPGVKHVAGDMFEGVPTGEAIFMKWILHDWDDERCKRVLKNCWRALPETGKVISVEFILPEDITNDPICRQIMYADLFMLAVNEGGKERTLVEFEGLAKESGFAAIRPFPCSGGLSVLEFHKKPLDD
>Af02G353200.1
MGSTLNQVKGSDDNEACMFAMQLASLSVLPMSLKAAIELDVLEIIAKAGPGAHLSPSEIASQLPTRNPEAPAMLDRILRLLASYSVLTCSLVDVPDGAVQRRYGLAPVCKFLVKNRDGVSISPLVLMNQDKVLMESWYYLKDAVLDGGIPFNKAYGMSAFEYHGTDGRFNKVFNRGMSDHSTLVMNKILETYSGFQGLKELVDVGGGVGATLNLIVSKYPHIKGTNFDLQHVIEDAPSYPGVEHVGGDMFVKVPSAEAIFMKWILHDWSDAHCLKLLQNCHKALPETGKVIIAESILPEAPETNLAANGVLHVDMIMLAHNPGGKERTRKEFEELANASGFTGFKLQCSAYNTWVMEFHK
>Af03G068300.1
MSVINFSSIQEMGEGEEHKRYAALTISSLISFPYVIRAAIKLGVFDIIAEVGPDAFLSSEDIASKIPNTSPTTPIALERILRMLLINDILKSSHADGELRPRYGLGKLGQYLVSGAPGASVAPTHLLAGDKVMVDGLYYLEDAVLDPSCEPFVKANGKTLFEFMGEDLRFRKVFHEAMRGGSIMTAAVIFDKYKGFEDVKDIVDVGGSSGAVVAEIVAKYPHIRGRNFDLPYVIANAPQFPGVEHVSGNMFESIPTAETIFMKSILHDWDDEQCIEILKNCWKALPDGGKVIDVDLVVPTKIENDLESLRVLGLDMTMMACCPRGRERTIEEFQYLRKAAGFAELKDFPVSNGLRVLEFHKSL
>Af03G281300.1
MTGEISEKNNDQFGDCLSGLGLSTFICTSMSLKAAIKLRVFEIIYAAGAGASLTAAEIAAEIPTKNPDAAASLEKILRILASNSLLTVSYEGGDADGKRVYYGLSSWASTLAPHGADGVSSAAHYLLPTNEAMVAAMHRLEDAVLERGAVPFQKVHGETIFEFAERDAGFGKVFHNAMSHASAMAMAKAFEVYDGFEKATEIVDVGGGVGTCLSMIVSKYPHVRGINFDLPYVVADAPKFPGVTHVGGDMFQAIPKTDTIFMKTILHDWNDEMCVKLLRNCWEALPPEGGKVIAVEYVLPPEVGNDTASLVATTHDILVMACCPEAKERTLKEFGHLSKAAGFAWMNNFPVGHGVYVMEFHKFITA
>Af03G281600.1
MCSSMENINLQASSSDRLGGFALSAFVCTSMALKAAINLKVFEIISNSGATGASLSAAEITAQIPTNNPNAAAALERILRILAANSLLTVSYKDEEEAAAYYGLSSWVASLVPHGAGAGDGASCVEHYLLNSHETIMAGLHRLEDAVMEEGAVPFERAHGMKLFELMEKESTGFRKVFHDAMNNVSAMVMARVFEIYDVFEKVKEIVDVGGGSGTCVAMIVSKYPHIRAINFDLPYVIANAPRHPGVTHVAGDMFQSVPKASDTIFMKCILHSWNDDKCVKLLRKCWEALPAEGGKVVVVEYVVPSTVRNDMASLNSTTHDILMMGVFLEGKERTLKEFRRLSQASGFAEMKNFPVAHGIQLLEFHKRRCSTTA
>Af06G064400.1
MATSGGRSESSKSSAARLAMMELANMMSVPMSLNAVVTLKVPDAIWDGGANTPLSAAEILSRLGRPVPPADPDNLQRILRMLVAYDVFREHPARKYSLTEIGQTLVAAGEEGLSYGAYVLQHHQEALVRAWPLLHTAVEDPAEEPFVRANGKSAYGYYGEKPEMNELMQKAMSGVSAPFIEAVLDGYAPGFAGIRRLVDVGGSSGACLRSIMERHPNVEEGVNFDLPEVVARAPNFPGITHVGGDMFQSIPSGDAIFMKWVLTTWTDDECKLILKNCFIALPEGGKVIACEPVLPEEIDSSSRTRALLEGDIFVMTIYRAKGKERTEEEFRQLGLAVGFSNFRAFYLDHFYTLLEFQK
>Af06G174700.1
MGGSIDGHELPVYHHFSHWVLHNWDDERCKRVLKNCWRALPEVGKVISAEFILPEDITNDPICHQIMYVDLLMLAVNEGGKERTLVEFEGLAKESGFAAIRSLPYSSGFSVLEFHKKPLDD
>Af07G058900.1
MTGAISEKNNDQFGDCLSGLGLSTFICTSMSLKAAIKLRGGDADGKRVYYGLSSWASTLEPHGADGISSAAHYLLPTNEAMVAAMHRLEDAVLERGAVPFQKVHGETIFEFAERDAGFGKVFHNAMSHASAMAMAKAFEVYDGFEKATEIVDVGGGVGTCLSMIVSKYPHVWGINYDLPYVVADAPKFPVPKMESERDSFVFELRRQSNLWSWNQFRTAINSNPFLIFRASFCRV
MGTPASSVLLQALQPWRRLEQIKTPLLASSSAVESRYHLMEETNVGSKAVDLGQLAGLPMALEAAIELNVIEILANSAGRESKLLSSSQIVEQIPARNPKAAAVTLERILRFLASNSVLTSTRNEKGEMLYGLTPVCEYFLPNKDGVSLATLVTFANDKVMMQSWHHLKEAVLTEGSVPPFNIAHDGMNAFEYNARDERFNKLFNDAMFNHSTLVLRQVLENYKEFERLEEIVDVGGGIGASLKMITSRYPHIKGTNFDLPHVIAEAPPCPGVKHVAGDMFEGVPTGEAIFMKWILHDWDDERCKRVLKNCWRALPETGKVISVEFILPEDITNDPICRQIMYADLFMLAVNEGGKERTLVEFEGLAKESGFAAIRPFPCSGGLSVLEFHKKPLDD
>Af02G353200.1
MGSTLNQVKGSDDNEACMFAMQLASLSVLPMSLKAAIELDVLEIIAKAGPGAHLSPSEIASQLPTRNPEAPAMLDRILRLLASYSVLTCSLVDVPDGAVQRRYGLAPVCKFLVKNRDGVSISPLVLMNQDKVLMESWYYLKDAVLDGGIPFNKAYGMSAFEYHGTDGRFNKVFNRGMSDHSTLVMNKILETYSGFQGLKELVDVGGGVGATLNLIVSKYPHIKGTNFDLQHVIEDAPSYPGVEHVGGDMFVKVPSAEAIFMKWILHDWSDAHCLKLLQNCHKALPETGKVIIAESILPEAPETNLAANGVLHVDMIMLAHNPGGKERTRKEFEELANASGFTGFKLQCSAYNTWVMEFHK
>Af03G068300.1
MSVINFSSIQEMGEGEEHKRYAALTISSLISFPYVIRAAIKLGVFDIIAEVGPDAFLSSEDIASKIPNTSPTTPIALERILRMLLINDILKSSHADGELRPRYGLGKLGQYLVSGAPGASVAPTHLLAGDKVMVDGLYYLEDAVLDPSCEPFVKANGKTLFEFMGEDLRFRKVFHEAMRGGSIMTAAVIFDKYKGFEDVKDIVDVGGSSGAVVAEIVAKYPHIRGRNFDLPYVIANAPQFPGVEHVSGNMFESIPTAETIFMKSILHDWDDEQCIEILKNCWKALPDGGKVIDVDLVVPTKIENDLESLRVLGLDMTMMACCPRGRERTIEEFQYLRKAAGFAELKDFPVSNGLRVLEFHKSL
>Af03G281300.1
MTGEISEKNNDQFGDCLSGLGLSTFICTSMSLKAAIKLRVFEIIYAAGAGASLTAAEIAAEIPTKNPDAAASLEKILRILASNSLLTVSYEGGDADGKRVYYGLSSWASTLAPHGADGVSSAAHYLLPTNEAMVAAMHRLEDAVLERGAVPFQKVHGETIFEFAERDAGFGKVFHNAMSHASAMAMAKAFEVYDGFEKATEIVDVGGGVGTCLSMIVSKYPHVRGINFDLPYVVADAPKFPGVTHVGGDMFQAIPKTDTIFMKTILHDWNDEMCVKLLRNCWEALPPEGGKVIAVEYVLPPEVGNDTASLVATTHDILVMACCPEAKERTLKEFGHLSKAAGFAWMNNFPVGHGVYVMEFHKFITA
>Af03G281600.1
MCSSMENINLQASSSDRLGGFALSAFVCTSMALKAAINLKVFEIISNSGATGASLSAAEITAQIPTNNPNAAAALERILRILAANSLLTVSYKDEEEAAAYYGLSSWVASLVPHGAGAGDGASCVEHYLLNSHETIMAGLHRLEDAVMEEGAVPFERAHGMKLFELMEKESTGFRKVFHDAMNNVSAMVMARVFEIYDVFEKVKEIVDVGGGSGTCVAMIVSKYPHIRAINFDLPYVIANAPRHPGVTHVAGDMFQSVPKASDTIFMKCILHSWNDDKCVKLLRKCWEALPAEGGKVVVVEYVVPSTVRNDMASLNSTTHDILMMGVFLEGKERTLKEFRRLSQASGFAEMKNFPVAHGIQLLEFHKRRCSTTA
>Af06G064400.1
MATSGGRSESSKSSAARLAMMELANMMSVPMSLNAVVTLKVPDAIWDGGANTPLSAAEILSRLGRPVPPADPDNLQRILRMLVAYDVFREHPARKYSLTEIGQTLVAAGEEGLSYGAYVLQHHQEALVRAWPLLHTAVEDPAEEPFVRANGKSAYGYYGEKPEMNELMQKAMSGVSAPFIEAVLDGYAPGFAGIRRLVDVGGSSGACLRSIMERHPNVEEGVNFDLPEVVARAPNFPGITHVGGDMFQSIPSGDAIFMKWVLTTWTDDECKLILKNCFIALPEGGKVIACEPVLPEEIDSSSRTRALLEGDIFVMTIYRAKGKERTEEEFRQLGLAVGFSNFRAFYLDHFYTLLEFQK
>Af06G174700.1
MGGSIDGHELPVYHHFSHWVLHNWDDERCKRVLKNCWRALPEVGKVISAEFILPEDITNDPICHQIMYVDLLMLAVNEGGKERTLVEFEGLAKESGFAAIRSLPYSSGFSVLEFHKKPLDD
>Af07G058900.1
MTGAISEKNNDQFGDCLSGLGLSTFICTSMSLKAAIKLRGGDADGKRVYYGLSSWASTLEPHGADGISSAAHYLLPTNEAMVAAMHRLEDAVLERGAVPFQKVHGETIFEFAERDAGFGKVFHNAMSHASAMAMAKAFEVYDGFEKATEIVDVGGGVGTCLSMIVSKYPHVWGINYDLPYVVADAPKFPVPKMESERDSFVFELRRQSNLWSWNQFRTAINSNPFLIFRASFCRV
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University