Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Aristolochia fimbriata
Species name
Aristolochia fimbriata is a species of flowering plant in the family Aristolochiaceae (birthwort family).
Species info
Gene sequence info
Aristolochia_fimbriata.HIDH.fa
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>Af01G262100.1
MGAISLSDTRFSSYVGNGHGQHGAVVEEIEGLIRLYKDGHVERPPIVPNVSAAFSTDPDVISRDVTVDDFNAVWARLYVPMRQTKLPLLVYFHGGGFCVGSAAWRSYHEFLSQLASTADCLIMSVNYRLAPEHPLPAAFEDGVSAVKWVRQQAVSSGEEHKWWASRCNFSKVFVGGDSAGACLAHNVVTRLRSPTALKPVTIGGVILIQPFFAGESRTASEKNMVQPASSALSLRASDAYWRLALPPGTNRDHPWCNPLSKSAAIYQNMENLNLPPTMVCISELDILKDRNLEFCAAMKSAGKSVEQVVYMGVGHAFQILHNYPLSQIRTQEMIAHIKAFIS
>Af03G226200.1
MLGLAGIISRTPLKTSLPKKRTEYRGVLAGICSDIAMTGAEDETEVVLDFPNAFRCYKSGRVDRFIGTDVVPPGVDPATGVASKDAALLPDVSARLFLPKIADPAAKNKLPVLLHFHGGIFVLHTPFSGAYSSYLASLAAAANALIVSVNYRRAPESPLPAAFDDSWAAFQWVTSHAGGSGPDPWLADHGDFARVFLAGDSVGAAISHHVARRLGEEGSAEATARPAGAILVHPFFWGTHEMGPKDEDPRRWGFIERIWRFLCPGTSGADDPLINPLVGWPTAMAGLGCGRVLVCVAEKDGLRSWGWAYYEGLRSSGWNGTVEIVESEGEDHVFHLKKPESGHVRELMNRLVDFINNSP
>Af03G226500.1
MSRRKLPIVVYVHGGLYVGGSPFSSIYHPYHNKLASKSKVIVVGVKFRVPPEVPFTTSFQDVWTTLKWVASNDSADGDPWLSKFGDFQKVTLMGDCTGCILVNEATRRAATEPLPNGVTINALVLVHPVFWGEKPIPGEEDFYEGLNLLGSGLWKLAQPNCGNGSDDPMLNPAGPLAPPLTDLACKRVLVCSAEKDWLKFRAWDYYTKLGLSGWAGDAEYWETDSEDHAFHLYDPSNEDAKILLQRVAAFINGRHASSMTSRVTPLF
>Af03G226400.1
METEKEIEKDLQPVCIVYKDGTVQRFDDSEEVPAGEDSKTGVSSRDVTVSEESDVTARLFLPRIKSGRKFPVVLYLHGGLYVGGSPSSSLYHPYMIQVAYKSRAVVIGVKFRVPPEVSFSTSIEDVWTALKWVASEATGGSDPWLTKYGDFEKLILMGDCTGCVLVNAVVHRSVKEPLPNGVKINGLVLVHPCFWGEEAIPGEEEYFRNLYDFSAGLWKLAMPDTPGCNDPVLNPTGPLSPPLTDLPCKRALICSAEKDWLKFRAWDYYTKLGTSGWAGDAEYWETDTEDHLFHIYDPSNEDAKVLLKRVDTFINGKPAPPIMRRVTALF
>Af03G226300.1
MAGEEENQVVFELPQLFRCYKSGRVDRFIGTDVVPAGVDPATGVASKDVTLVPPDVVSARLFLPKIADPAKKLPVFVHFHGGVFVIQTPFSASSHNFLTSLAAAAGAIVVSVHYRRAPESPLPAAFEDSWAAFRWVVSHGGGSGPEPWLAEHGDFGRVFVGGESAGATISHYVARRAGREGGAAGPTIAGAVLVHPYFWGIHEMGPKDVSPQQSGFMEKFWRFVCPGTSGGDDPLINPLAGWPAAMAEVGAGRVLVCVAEKDRMRSWGLAYYEGLRSSGWKGTAEMFESEGEEHVFHLLKAESDKSRELKSKIVDFIKQTDQ
>Af05G126700.1
MEVAEDPDQMVVQEYPPFVRIYKSGRVERLKGNDVVPASVDSSSAVSSKDVAISGDVSARLFLPNNNDADPSEEKKKKKLPVLLYVHGGGFVIETPFSPAYHAYVGSLAAAAGVVAVSVHYRRAPEHPLPAAYDDAWTALAWVASHADGAGPEPWLADHADCTKVFLAGDSAGGNIVHDLLLRAGEGGIAGGIAAHPPVGAVLVHPYFWGARPTHAPPGADPTALWPGMEKFWKFVCPNTTGEDDPRTNPHAGGPAGFASLAGKRVLVCLAEKDFLTVWGRMYCDALGSGGYYKGTVEMLESEGEGHVFHLFNPECQKAKEMMSRVVDFINRDD
>Af05G149200.1
MYDHNPIPVSPMLEEASSSPRLNAVAEETNVERRAGGTYDRRLHLHLFPLSACATPRARGNSFQGGDFAGVFLAGNSAGAAISHHIACHLGEQGSATATARPAGAILVHSGRRLRRGLSRRE
>Af05G181600.1
MATSVPHEVENCRNTLRVFSDGSIVRSTQPSFNVPVHDDGTVVWKDVEFDPTHRLSLRLYKPAPSPQSAGAAPKLPIFYYFHGGGFCIGSRAWPTCQNYCLHLARELRAVVVAPDYRLAPEDRLPAALHDAFAAVEWLREQAAAEEPDAWLDGVADYGRVFISGDSAGGNIAHYLAVRLGAGSPAVTPVRVRGYVYLAPFFGGTVRTKSEEMSPKDAFFPLDLNDRFWRLSLPEGENTDHLISNPFGLGSPSLERVELDPILVVVGTADLLRDRAKEYALKLQGWGKRVQFAEFAEQQHGFFTIDPFSPVSNELMRLIKRFMAENSES
MGAISLSDTRFSSYVGNGHGQHGAVVEEIEGLIRLYKDGHVERPPIVPNVSAAFSTDPDVISRDVTVDDFNAVWARLYVPMRQTKLPLLVYFHGGGFCVGSAAWRSYHEFLSQLASTADCLIMSVNYRLAPEHPLPAAFEDGVSAVKWVRQQAVSSGEEHKWWASRCNFSKVFVGGDSAGACLAHNVVTRLRSPTALKPVTIGGVILIQPFFAGESRTASEKNMVQPASSALSLRASDAYWRLALPPGTNRDHPWCNPLSKSAAIYQNMENLNLPPTMVCISELDILKDRNLEFCAAMKSAGKSVEQVVYMGVGHAFQILHNYPLSQIRTQEMIAHIKAFIS
>Af03G226200.1
MLGLAGIISRTPLKTSLPKKRTEYRGVLAGICSDIAMTGAEDETEVVLDFPNAFRCYKSGRVDRFIGTDVVPPGVDPATGVASKDAALLPDVSARLFLPKIADPAAKNKLPVLLHFHGGIFVLHTPFSGAYSSYLASLAAAANALIVSVNYRRAPESPLPAAFDDSWAAFQWVTSHAGGSGPDPWLADHGDFARVFLAGDSVGAAISHHVARRLGEEGSAEATARPAGAILVHPFFWGTHEMGPKDEDPRRWGFIERIWRFLCPGTSGADDPLINPLVGWPTAMAGLGCGRVLVCVAEKDGLRSWGWAYYEGLRSSGWNGTVEIVESEGEDHVFHLKKPESGHVRELMNRLVDFINNSP
>Af03G226500.1
MSRRKLPIVVYVHGGLYVGGSPFSSIYHPYHNKLASKSKVIVVGVKFRVPPEVPFTTSFQDVWTTLKWVASNDSADGDPWLSKFGDFQKVTLMGDCTGCILVNEATRRAATEPLPNGVTINALVLVHPVFWGEKPIPGEEDFYEGLNLLGSGLWKLAQPNCGNGSDDPMLNPAGPLAPPLTDLACKRVLVCSAEKDWLKFRAWDYYTKLGLSGWAGDAEYWETDSEDHAFHLYDPSNEDAKILLQRVAAFINGRHASSMTSRVTPLF
>Af03G226400.1
METEKEIEKDLQPVCIVYKDGTVQRFDDSEEVPAGEDSKTGVSSRDVTVSEESDVTARLFLPRIKSGRKFPVVLYLHGGLYVGGSPSSSLYHPYMIQVAYKSRAVVIGVKFRVPPEVSFSTSIEDVWTALKWVASEATGGSDPWLTKYGDFEKLILMGDCTGCVLVNAVVHRSVKEPLPNGVKINGLVLVHPCFWGEEAIPGEEEYFRNLYDFSAGLWKLAMPDTPGCNDPVLNPTGPLSPPLTDLPCKRALICSAEKDWLKFRAWDYYTKLGTSGWAGDAEYWETDTEDHLFHIYDPSNEDAKVLLKRVDTFINGKPAPPIMRRVTALF
>Af03G226300.1
MAGEEENQVVFELPQLFRCYKSGRVDRFIGTDVVPAGVDPATGVASKDVTLVPPDVVSARLFLPKIADPAKKLPVFVHFHGGVFVIQTPFSASSHNFLTSLAAAAGAIVVSVHYRRAPESPLPAAFEDSWAAFRWVVSHGGGSGPEPWLAEHGDFGRVFVGGESAGATISHYVARRAGREGGAAGPTIAGAVLVHPYFWGIHEMGPKDVSPQQSGFMEKFWRFVCPGTSGGDDPLINPLAGWPAAMAEVGAGRVLVCVAEKDRMRSWGLAYYEGLRSSGWKGTAEMFESEGEEHVFHLLKAESDKSRELKSKIVDFIKQTDQ
>Af05G126700.1
MEVAEDPDQMVVQEYPPFVRIYKSGRVERLKGNDVVPASVDSSSAVSSKDVAISGDVSARLFLPNNNDADPSEEKKKKKLPVLLYVHGGGFVIETPFSPAYHAYVGSLAAAAGVVAVSVHYRRAPEHPLPAAYDDAWTALAWVASHADGAGPEPWLADHADCTKVFLAGDSAGGNIVHDLLLRAGEGGIAGGIAAHPPVGAVLVHPYFWGARPTHAPPGADPTALWPGMEKFWKFVCPNTTGEDDPRTNPHAGGPAGFASLAGKRVLVCLAEKDFLTVWGRMYCDALGSGGYYKGTVEMLESEGEGHVFHLFNPECQKAKEMMSRVVDFINRDD
>Af05G149200.1
MYDHNPIPVSPMLEEASSSPRLNAVAEETNVERRAGGTYDRRLHLHLFPLSACATPRARGNSFQGGDFAGVFLAGNSAGAAISHHIACHLGEQGSATATARPAGAILVHSGRRLRRGLSRRE
>Af05G181600.1
MATSVPHEVENCRNTLRVFSDGSIVRSTQPSFNVPVHDDGTVVWKDVEFDPTHRLSLRLYKPAPSPQSAGAAPKLPIFYYFHGGGFCIGSRAWPTCQNYCLHLARELRAVVVAPDYRLAPEDRLPAALHDAFAAVEWLREQAAAEEPDAWLDGVADYGRVFISGDSAGGNIAHYLAVRLGAGSPAVTPVRVRGYVYLAPFFGGTVRTKSEEMSPKDAFFPLDLNDRFWRLSLPEGENTDHLISNPFGLGSPSLERVELDPILVVVGTADLLRDRAKEYALKLQGWGKRVQFAEFAEQQHGFFTIDPFSPVSNELMRLIKRFMAENSES
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University