Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Aristolochia fimbriata
Species name
Aristolochia fimbriata is a species of flowering plant in the family Aristolochiaceae (birthwort family).
Species info
Gene sequence info
Aristolochia_fimbriata.4CL.fa
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>Af01G043700.1
MGSASGEFIFRSKLPDIDIPKDLTLHSYCFQNIDSHRSRPCIINGSTGDVYTYGEVELTARKVAAGLHRLGVEKGQVIMLLLPNSPEFIFAFMGASYRGAVSTTANPFYTPAEIAKQARASDARVVVTQACHVDKVRDLAEERGIKIVTVDAPPPGCLHFSELAAADEAELPAVDVSPDDVVALPYSSGTTGLPKGVMLTHRGQVTSVAQQVDGENPNLYMCSDDVILCVLPMFHIYSLNSVLFCGLRVGAAILVMAKFDIASLMELVQRYRVTITPIVPPIVLAITKSPLVDSHDLSSVRTVMSGAAPMGKELEDSVRTKFPNAKLGQGYGMTEAGPVLSMCLAFAKEPFEIKSGSCGTVVRNAEMKIVDPETGASLPRNQPGEICIRGAQIMKGYLNDPEATERTIDKEGWLHTGDIGYVDDDDELFIVDRLKEIIKYKGFQVAPAELEALLITHPFIADAAVVSMKDELAGEVPVAFVVKSNGSVITEEEIKQFISKQVIFYKRISRVFFTDAIPKAPSGKILRKDLRARLAAGIPN
>Af02G002300.1
MISVASHETQTKISSPTPAVGDSSPETVIFRSKLPDIPISNHLPLHTYCFEKASEFSDRPCLISGSNGKTYTFAETQKLCQRTGAGLSKLGIKKGEVVMLLLQNCPEFVFAFMGASMLGAVTTTANPFCTTSEIFKQYTASGARLVITQSHYVDKLRDETNFPKIGRDNFTVVTVDDPPADDCLSFSEMISSADERDLPTVSIDPDDAVALPFSSGTTGLPKGVILTHKSLITSIAQQVDGENPNLFLTSDDIVLCVLPLFHIYSLNSVLLCSLRAGAGVLIMQKFEIGSLLELIQRHRVSVATVVPPLVLALAKNPMVEKFDLSSIRIVLSGAAPLGKELEEALRSRVPQAIFGQGYGMTEAGPVLSMCLGFAKQSLPTKSGSCGTVVRNAELKVIDPETGFSLRHNQPGEICIRGAQIMKGYLNDPEATASTIDVEGWLHTGDIGYVDDDEEVFIVDRVKELIKFKGFQVPPAEIEALLVSHPSIADAAVVPQKDDAAGEVPVAFIVRANDFDLTEEAVKEFIAKQVVFYKRLHKVYFVHAIPKSPAGKILRKDLRAKLAQAAAT
>Af03G090200.1
MAQEEHVFRSQYPAVPVPDLTLPEFVLQDADKYADKVAVVEAVTGKSLTYSQLVRDTARFAAALRTTAGLGKGGVVVVVLPNVAEYPVIALGIMAAGGVFSGANPAAHPSEIRKQAEDAGAAVVVTSGSVHEKVSGLAAAVPIIVVGEERVEGAMHWEEFLSTGEAASGGAAVSQDDLCALPYSSGTTGASKGVMLTHRNLVANLCSTLFAVEEEMVGNVTTLGLMPFFHIYGITGICCATLRNKGKVVAMSRFELRSFLASLIAHEVNFAPIVPPIMLALVKNPIVDEFDLTKLKLRAVMTAAAPLAPELLSAFEEKFPGVQVQEAYGLTEHSCITLTHGDPKREHGISKRNSVGFILPNLEVKFVDPETGKSLPKNTSGEVCVRSQCVMKGYYRKDYETERTIDSDGWLHTGDVGYIDDDGDIFIIDRIKELIKYKGFQVAPAELEAILLTHPSVDDAAVVPLPDEEAGEVPAACVVMNPNANETEEDIINYVASNVATYKKVRVVQFVDAIPKSHSVCTSLFDRVLLGTPTLLSARRYRKDLQELLIRKLHVIPDF
>Af03G090210.1
MAQEEHIFRSKFPGVPVPDLTLPEFVLQDADKYADKVAVVDAVTGKSFTYAEVVRDTARFASALRTTAGLTKGGVVVVVLPNVAEYPVITLGIMAAGGVFSGANPAAHPLEIRKQVKDCEAAVIVTDASIYEKVKGHGVATPIIVVGEERVEGTMHWDDFLSTAQASGGVAASQDDLCALPYSSGTTGASKGVMLTHRNLVANLCSTLFAVDEELIGQVTTLGLMPFFHIYGITGICCATLRNKGKVVAMGRFELRSFLSALIAHEVNFAPIVPPIMLALVKNPIVDEFDLTQLKLRAVMTAAAPLAPELLSAFEKKFPGVQVQEAYGLTEHSCITLTHGDQMTENRVSKKNSVGFILPNLEVKFLDPETGKSLPANTPGELCVRSQCVMKGYYRKAAETGQTIDSDGWLHTGDVGYIDDDGDIFIIDRIKELIKHKGFQVAPAELEAILLTHPSVDDVAVVPLPDEEAGEIPAACVVKNPNAKVTEQDIMNYVASNVAAYKKVRVVQFVDAIPKSHSGKIMRRLIRDSMIKTLGGHPQIMSRL
>Af07G009700.1
MMEKSGYGKDGIYRSLRPPILFPREQSLSMVSFLFQKSSSYQDRLALVDSETGEALDFGQLKTMVQRVSHGFVKLGLKKGDVILILAPNSIEYPVCFLGIVASGAIATTVNPLYTVAEISKQAKDSGAKLVVTVPALWDKVKDLGLRPLLLGPKNESSKLIASNYGAIHFSDLGEMAGRVSDFPQSSINQTDTAALLYSSGTTGVSKGVILTHRNFITASLMATSDQDFDGEGPNVFVCFLPMFHIFGLSILTYAQLRRGNTVVVMARFELEAVLQSIEKYRVSYMFGVPPVMIALAKQNWGRKYDLSSLKKIGSGAAPLGKDIMEECARVFPDAQIIQGYGMTESCGICSLENPKEAVRHYGSTGCLVQGVEAKIVSVDTLKPLPPAQLGEIWIRGPNMMRGYFNDQQATKLTIDKQGWLHTGDLGYFDEEGRLFVVDRIKELIKYKGFQVAPAELEGVLLSHPEILDAVVIPYPDAEAGEVPIGYVVRLPSSSLNEEDVKKFVANQVAHFKRLRRVTFVNSVPKSAAGKILRRELIEKVRSKL
MGSASGEFIFRSKLPDIDIPKDLTLHSYCFQNIDSHRSRPCIINGSTGDVYTYGEVELTARKVAAGLHRLGVEKGQVIMLLLPNSPEFIFAFMGASYRGAVSTTANPFYTPAEIAKQARASDARVVVTQACHVDKVRDLAEERGIKIVTVDAPPPGCLHFSELAAADEAELPAVDVSPDDVVALPYSSGTTGLPKGVMLTHRGQVTSVAQQVDGENPNLYMCSDDVILCVLPMFHIYSLNSVLFCGLRVGAAILVMAKFDIASLMELVQRYRVTITPIVPPIVLAITKSPLVDSHDLSSVRTVMSGAAPMGKELEDSVRTKFPNAKLGQGYGMTEAGPVLSMCLAFAKEPFEIKSGSCGTVVRNAEMKIVDPETGASLPRNQPGEICIRGAQIMKGYLNDPEATERTIDKEGWLHTGDIGYVDDDDELFIVDRLKEIIKYKGFQVAPAELEALLITHPFIADAAVVSMKDELAGEVPVAFVVKSNGSVITEEEIKQFISKQVIFYKRISRVFFTDAIPKAPSGKILRKDLRARLAAGIPN
>Af02G002300.1
MISVASHETQTKISSPTPAVGDSSPETVIFRSKLPDIPISNHLPLHTYCFEKASEFSDRPCLISGSNGKTYTFAETQKLCQRTGAGLSKLGIKKGEVVMLLLQNCPEFVFAFMGASMLGAVTTTANPFCTTSEIFKQYTASGARLVITQSHYVDKLRDETNFPKIGRDNFTVVTVDDPPADDCLSFSEMISSADERDLPTVSIDPDDAVALPFSSGTTGLPKGVILTHKSLITSIAQQVDGENPNLFLTSDDIVLCVLPLFHIYSLNSVLLCSLRAGAGVLIMQKFEIGSLLELIQRHRVSVATVVPPLVLALAKNPMVEKFDLSSIRIVLSGAAPLGKELEEALRSRVPQAIFGQGYGMTEAGPVLSMCLGFAKQSLPTKSGSCGTVVRNAELKVIDPETGFSLRHNQPGEICIRGAQIMKGYLNDPEATASTIDVEGWLHTGDIGYVDDDEEVFIVDRVKELIKFKGFQVPPAEIEALLVSHPSIADAAVVPQKDDAAGEVPVAFIVRANDFDLTEEAVKEFIAKQVVFYKRLHKVYFVHAIPKSPAGKILRKDLRAKLAQAAAT
>Af03G090200.1
MAQEEHVFRSQYPAVPVPDLTLPEFVLQDADKYADKVAVVEAVTGKSLTYSQLVRDTARFAAALRTTAGLGKGGVVVVVLPNVAEYPVIALGIMAAGGVFSGANPAAHPSEIRKQAEDAGAAVVVTSGSVHEKVSGLAAAVPIIVVGEERVEGAMHWEEFLSTGEAASGGAAVSQDDLCALPYSSGTTGASKGVMLTHRNLVANLCSTLFAVEEEMVGNVTTLGLMPFFHIYGITGICCATLRNKGKVVAMSRFELRSFLASLIAHEVNFAPIVPPIMLALVKNPIVDEFDLTKLKLRAVMTAAAPLAPELLSAFEEKFPGVQVQEAYGLTEHSCITLTHGDPKREHGISKRNSVGFILPNLEVKFVDPETGKSLPKNTSGEVCVRSQCVMKGYYRKDYETERTIDSDGWLHTGDVGYIDDDGDIFIIDRIKELIKYKGFQVAPAELEAILLTHPSVDDAAVVPLPDEEAGEVPAACVVMNPNANETEEDIINYVASNVATYKKVRVVQFVDAIPKSHSVCTSLFDRVLLGTPTLLSARRYRKDLQELLIRKLHVIPDF
>Af03G090210.1
MAQEEHIFRSKFPGVPVPDLTLPEFVLQDADKYADKVAVVDAVTGKSFTYAEVVRDTARFASALRTTAGLTKGGVVVVVLPNVAEYPVITLGIMAAGGVFSGANPAAHPLEIRKQVKDCEAAVIVTDASIYEKVKGHGVATPIIVVGEERVEGTMHWDDFLSTAQASGGVAASQDDLCALPYSSGTTGASKGVMLTHRNLVANLCSTLFAVDEELIGQVTTLGLMPFFHIYGITGICCATLRNKGKVVAMGRFELRSFLSALIAHEVNFAPIVPPIMLALVKNPIVDEFDLTQLKLRAVMTAAAPLAPELLSAFEKKFPGVQVQEAYGLTEHSCITLTHGDQMTENRVSKKNSVGFILPNLEVKFLDPETGKSLPANTPGELCVRSQCVMKGYYRKAAETGQTIDSDGWLHTGDVGYIDDDGDIFIIDRIKELIKHKGFQVAPAELEAILLTHPSVDDVAVVPLPDEEAGEIPAACVVKNPNAKVTEQDIMNYVASNVAAYKKVRVVQFVDAIPKSHSGKIMRRLIRDSMIKTLGGHPQIMSRL
>Af07G009700.1
MMEKSGYGKDGIYRSLRPPILFPREQSLSMVSFLFQKSSSYQDRLALVDSETGEALDFGQLKTMVQRVSHGFVKLGLKKGDVILILAPNSIEYPVCFLGIVASGAIATTVNPLYTVAEISKQAKDSGAKLVVTVPALWDKVKDLGLRPLLLGPKNESSKLIASNYGAIHFSDLGEMAGRVSDFPQSSINQTDTAALLYSSGTTGVSKGVILTHRNFITASLMATSDQDFDGEGPNVFVCFLPMFHIFGLSILTYAQLRRGNTVVVMARFELEAVLQSIEKYRVSYMFGVPPVMIALAKQNWGRKYDLSSLKKIGSGAAPLGKDIMEECARVFPDAQIIQGYGMTESCGICSLENPKEAVRHYGSTGCLVQGVEAKIVSVDTLKPLPPAQLGEIWIRGPNMMRGYFNDQQATKLTIDKQGWLHTGDLGYFDEEGRLFVVDRIKELIKYKGFQVAPAELEGVLLSHPEILDAVVIPYPDAEAGEVPIGYVVRLPSSSLNEEDVKKFVANQVAHFKRLRRVTFVNSVPKSAAGKILRRELIEKVRSKL
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University