Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Zea mays
Species name
Maize (Zea mays) is a species of monocot in the family Poaceae (grass family).
Species info
Gene sequence info
Zea_mays.4CL.fa
Download
>rna-NM_001365506.1
MVSPTEPQAETTVFRSTLPDIAIPDHLPLHDYVLERLAERRDRACLIDGATGETLTFGDVDRLSRRVAAGMRACLGVRSGGTVMLLLPNSVEFALAFLACSRLGAAATTANPLHTPPEIAKQAAASGATVVITEPAFVGKVRGLAGVAVVATGDGAEGCVSFSDLASSADDGSAALPEAAAAATAIDVANDVVALPYSSGTTGLPKGVMLSHRGLVTSVAQLVDGDNPNLYFREDDVVLCVLPMFHVYSLHSILLCGMRAGAALVIMKRFDTLRMFELVKRHGITIVPLVLPIAVEMVKSDAIDRHDLSSVRMVISGAAPMGKELQDLLRAKLPRAVLGQGYGMTEAGPVLSMCMAFAKEPLPVKSGACGTVVRNAELKIIDPETGLSLHRNQPGEICIRGKQLMKGYLNNPEATAKTIDSEGWLHTGDIGYVDDGDEIFIVDRLKELIKYKGFQVAPAELEAMLIAHPSIADAAVVQMKDDSCGEIPVAFVVASGGSGITEDEIKQYVAKQVVFYKRLHKIFFVEAIPKAPSGKILRKDLRAKLASGFSNGSSC
>rna-XM_008674394.4
MARTAAPAAGYGEDGVYRSPRPAVRIESDTGLSLNDLLFRRADVCPSALALVDSATGQSLTFAAFRSAVLTTAVALSSRAGVRRGDVVLFFAPNCFLYPVCFFAVTALGAVATTANPLYTPREVAKQATDSRAKLAITVSELLPKIVDLGFPTILLDGGGDGDAASAAASKPQGASVTLYSDLVSGARETEYRRPPTKQSDTTALMYSSGTTGASKGVILTHRNFISAAAMMTADQDALGEGPNVFLCFLPMFHIFGLSVITFAQMQRGNSVVVMSRFDMDSVMAAVQRHRVTHLFCVPPVMIALAKLGSVGKYDLSSLRFIGSGAAPLGKDVMEGVAKNFPEAVIAQGYGMTETCGIISLEYPEKGQIRQFGSTGALVSGVEAKIVDVETLICLPPNQLGEICVRGPNIMQGYFNNVQATEFTIKQGWLHTGDIGYFDEGGQLFVVDRLKELIKYKGFQIAPAELEGLLLSHPEILDAVVIPFPDAEAGEVPIAYVVRSSESSLTEVDVQKFIEKQVAYYKKLRRVTFVDSVPKSASGKILRRELISKVRSSKL
>rna-XM_020547235.2
MDAVVIPLPNAKAGEVPIAYIVRSPDSSLTEVDVQKFIEKQVTTTSPTGTHKLANPKGEVATARAAAACNTIMWL
>rna-NM_001153038.2
MVGTVSLAAGYGSDGVYRSPRLVAAIASDPGLSVTDLVLRRAAACPSAPALVDAATGRALTFGALRSAVLVAAAALSSRAGVRRGDAVLLLAPNCVLYPVCFLAVTALGAVATTANPLYTPREIAKQAADARARLVVTVSDLLPKISGLRLPIVLLDGDGAPVPSGCPSSNVTLYSDLVAGVQEAEYRHTPIGQGDTAALFYSSGTTGESKGVVLTHRNFIAAATMVTSDQDELGEGHNVFLCFLPMFHIFGMSVITLGQLQRGNAVVVMARFDVDAVLAAIERHRVTYLFCAPPAMIALAKHSRGGRYDLSSLRCIGSGAAPLGKDVMVAMADRFPGVDIIQGYGMTETCGIISLEYVQKGCARQFGSTGALVTGVEAKIVNAKTMKHLPPSQLGEICVRGPNIMEGYFNNVQATESTIKNGWLHTGDLGYFDERGQLHVVDRLKELIKYKGFQIAPAELEGLLLSHPEILDAAVIPYPDAEAGEVPIAYVVLSPKSSLAEADVQKFIEKQVAHYKRLRKVTFVGSVPKSAAGKILRRELIAQVRLSKL
>rna-NM_001156842.1
MGDAAIAVVHEADEEEQEHIFRSRFPPVDLPDDVTVPEFVLAGAEAYADKVALVEAAPGGRSYTYGEVARDVARFARALRSVGVRKGHVVVVALPNLAVYPVVSLGIMSAGAVFSGVNPRAIAAEIKKQVEDSDAKLVVTNEVAYDKVKDAGVPVIGIGDDMERLPGAISWDELLAAADRTGAPVVALDPVQQSDLCALPYSSGTTGVSKGVMLSHRNLVSNLCSSMFAVGEELVGQVVTLGLMPFFHIYGITGICCSTLRHKGTVVVMDRFDLRTFLGALVTHRVMFAPVVPPVMLAMVKSPVADDFDLSGLALRSIMTAAAPLAPDLLAAFEKKFPGVQVEEAYGLTEHSCITLTHAASGDDARQGPVQVAKKNSVGFILPNLEVKFVDPDTGRSLPKNTPGEICVRSQAVMQGYYRKKEETERTIDAKGWLHTGDVGYIDDDGDVFIVDRIKELIKYKGFQVAPAELEAILLSHPSVQDAAVFGLPDEEAGEVPVSCVVRRCGASESEADIMAYVAGRVASYKKLRLLQFVDVIHKSVSGKILRRQLRDEFVSRTKTAAA
>rna-NM_001153005.1
MGDAAIAAVHLHESEEEHIFRSRFPPVAVPDDVTVPEFVLADAEAYADKTALVEAAPGGRSYTYGELVRDVARFARALRSIGVRRGHVVVVALPNLAVYPVVSLGIMSAGAVFSGVNPRAVAAEIKKQVEDSEARLVVADAVAYDKVKDAGVPVIGIGDVARLPGAIGWDELLAMADRAGAPVVALEPAQQSDLCALPYSSGTTGVSKGVMLSHRNLVSSLCSSMFAVGQELVGQVVTLGLMPFFHIYGITGICCATLRHKGTVVVMDRFDLRAFLGALLTHRVMFAPVVPPVMLAMVKSPVADEFDLSGLALRSVMTAAAPLAPDLLAAFERKFPGVQVEEAYGLTEHSCITLTHASGGGEDVGSAVQVAKKKSVGFILPNLEVKFVDPDTGRSLPKNTPGEICVRSQAVMQGYYRKKEETERTIDAAGWLHTGDVGYIDDDGDVFIVDRIKELIKYKGFQVAPAELEAILLSHPSVEDAAVFGLPDEEAGEVPASCVVRRRGAPESEADMMAYVAGRVASYKKLRLLRFVDAIPKSVSGKILRRQLRDEFVKKTAAA
>rna-XM_008680760.3
MITVAAPEAQPQVAAAAAVAAPEETVFRSKLPDIDIPTHLPLHDYCFSRAAEAAGAPCLIAAATGRTYTYAETRLLCRKAAACLHGLGVAQGDRVMLLLQNSVEFVLAFFGASFLGAVTTAANPFCTPQEIHKQFSASGAKVVVTHSAYVAKLRHGAFPRIGTVSGGGVDGNALLTVLTIDGDAADTPEGCLAFWELLTSGDGDALPEVSISPDDPVALPFSSGTTGLPKGVVLTHGGQVTNVAQQVDGANPNLYMREGDVALCVLPLFHIFSLNSVLLCAMRAGAAVMLMPKFEMGAMLEGIQRWRVTVAAVVPPLVLALAKNPALEKYDLSSIRIVLSGAAPLGKDLVDALRARVPQAVFGQGYGMTEAGPVLSMCPAFAKEPAPAKPGSCGTVVRNAELKVVDPDTGLSLGRNLPGEICIRGPQIMKGYLNDPEATARTIDVHGWLHTGDIGYVDDDDEVFIVDRVKELIKFKGFQVPPAELEALLVAHPSIADAAVVPQKDEAAGEVPVAFVVRAADADIAEDAIKEFISKQVVFYKRLHKVYFTPSIPKSASGKILRRELRAKLAAAATA
>rna-NM_001111788.2
MGSVDAAIAVPVPAAEEKAVEEKAVVFRSKLPDIEIDSSMALHTYCFGKMGEVAERACLVDGLTGASYTYAEVESLSRRAASGLRAMGVGKGDVVMSLLRNCPEFAFTFLGAARLGAATTTANPFYTPHEVHRQAEAAGARLIVTEACAVEKVREFAAERGIPVVTVDGRFDGCVEFAELIAAEELEADADIHPDDVVALPYSSGTTGLPKGVMLTHRSLITSVAQQVDGENPNLYFRKDDVVLCLLPLFHIYSLNSVLLAGLRAGSTIVIMRKFDLGALVDLVRRYVITIAPFVPPIVVEIAKSPRVTAGDLASIRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPYPVKSGSCGTVVRNAELKIVDPDTGAALGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHTGDIGYVDDDDEIFIVDRLKEIIKYKGFQVPPAELEALLITHPEIKDAAVVSMNDDLAGEIPVAFIVRTEGSQVTEDEIKQFVAKEVVFYKKIHKVFFTESIPKNPSGKILRKDLRARLAAGVH
>rna-NM_001175023.1
MPKGVMLTHRSLVTSVAQQVDGENPNLYFSKDDVVLCVLPLFHIYSLNSVLLAGLRAGCAIVIMRKFEIGALVELVRAHGVTVAPFVPPIVVEIAKSPRVGAADLASIRMVMSGAAPMGKDLQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFEVKSGSCGTVVRNAELKIVDPDTSASLGRNQPGEICIRGEQIMKGYLNDPEATKNTIDKDGWLHTGDIGYVDDDDEIFIVDRLKEIIKYKGFQVPPAELEALLITHPEIKDAAVVSMKDEVAGEVPVAFIIRSEGSEISENEIKQFVAKEVVFYKRINRVFFTDSIPKNPSGKILRKDLRARLAAGIPSSDNTQSKS
MVSPTEPQAETTVFRSTLPDIAIPDHLPLHDYVLERLAERRDRACLIDGATGETLTFGDVDRLSRRVAAGMRACLGVRSGGTVMLLLPNSVEFALAFLACSRLGAAATTANPLHTPPEIAKQAAASGATVVITEPAFVGKVRGLAGVAVVATGDGAEGCVSFSDLASSADDGSAALPEAAAAATAIDVANDVVALPYSSGTTGLPKGVMLSHRGLVTSVAQLVDGDNPNLYFREDDVVLCVLPMFHVYSLHSILLCGMRAGAALVIMKRFDTLRMFELVKRHGITIVPLVLPIAVEMVKSDAIDRHDLSSVRMVISGAAPMGKELQDLLRAKLPRAVLGQGYGMTEAGPVLSMCMAFAKEPLPVKSGACGTVVRNAELKIIDPETGLSLHRNQPGEICIRGKQLMKGYLNNPEATAKTIDSEGWLHTGDIGYVDDGDEIFIVDRLKELIKYKGFQVAPAELEAMLIAHPSIADAAVVQMKDDSCGEIPVAFVVASGGSGITEDEIKQYVAKQVVFYKRLHKIFFVEAIPKAPSGKILRKDLRAKLASGFSNGSSC
>rna-XM_008674394.4
MARTAAPAAGYGEDGVYRSPRPAVRIESDTGLSLNDLLFRRADVCPSALALVDSATGQSLTFAAFRSAVLTTAVALSSRAGVRRGDVVLFFAPNCFLYPVCFFAVTALGAVATTANPLYTPREVAKQATDSRAKLAITVSELLPKIVDLGFPTILLDGGGDGDAASAAASKPQGASVTLYSDLVSGARETEYRRPPTKQSDTTALMYSSGTTGASKGVILTHRNFISAAAMMTADQDALGEGPNVFLCFLPMFHIFGLSVITFAQMQRGNSVVVMSRFDMDSVMAAVQRHRVTHLFCVPPVMIALAKLGSVGKYDLSSLRFIGSGAAPLGKDVMEGVAKNFPEAVIAQGYGMTETCGIISLEYPEKGQIRQFGSTGALVSGVEAKIVDVETLICLPPNQLGEICVRGPNIMQGYFNNVQATEFTIKQGWLHTGDIGYFDEGGQLFVVDRLKELIKYKGFQIAPAELEGLLLSHPEILDAVVIPFPDAEAGEVPIAYVVRSSESSLTEVDVQKFIEKQVAYYKKLRRVTFVDSVPKSASGKILRRELISKVRSSKL
>rna-XM_020547235.2
MDAVVIPLPNAKAGEVPIAYIVRSPDSSLTEVDVQKFIEKQVTTTSPTGTHKLANPKGEVATARAAAACNTIMWL
>rna-NM_001153038.2
MVGTVSLAAGYGSDGVYRSPRLVAAIASDPGLSVTDLVLRRAAACPSAPALVDAATGRALTFGALRSAVLVAAAALSSRAGVRRGDAVLLLAPNCVLYPVCFLAVTALGAVATTANPLYTPREIAKQAADARARLVVTVSDLLPKISGLRLPIVLLDGDGAPVPSGCPSSNVTLYSDLVAGVQEAEYRHTPIGQGDTAALFYSSGTTGESKGVVLTHRNFIAAATMVTSDQDELGEGHNVFLCFLPMFHIFGMSVITLGQLQRGNAVVVMARFDVDAVLAAIERHRVTYLFCAPPAMIALAKHSRGGRYDLSSLRCIGSGAAPLGKDVMVAMADRFPGVDIIQGYGMTETCGIISLEYVQKGCARQFGSTGALVTGVEAKIVNAKTMKHLPPSQLGEICVRGPNIMEGYFNNVQATESTIKNGWLHTGDLGYFDERGQLHVVDRLKELIKYKGFQIAPAELEGLLLSHPEILDAAVIPYPDAEAGEVPIAYVVLSPKSSLAEADVQKFIEKQVAHYKRLRKVTFVGSVPKSAAGKILRRELIAQVRLSKL
>rna-NM_001156842.1
MGDAAIAVVHEADEEEQEHIFRSRFPPVDLPDDVTVPEFVLAGAEAYADKVALVEAAPGGRSYTYGEVARDVARFARALRSVGVRKGHVVVVALPNLAVYPVVSLGIMSAGAVFSGVNPRAIAAEIKKQVEDSDAKLVVTNEVAYDKVKDAGVPVIGIGDDMERLPGAISWDELLAAADRTGAPVVALDPVQQSDLCALPYSSGTTGVSKGVMLSHRNLVSNLCSSMFAVGEELVGQVVTLGLMPFFHIYGITGICCSTLRHKGTVVVMDRFDLRTFLGALVTHRVMFAPVVPPVMLAMVKSPVADDFDLSGLALRSIMTAAAPLAPDLLAAFEKKFPGVQVEEAYGLTEHSCITLTHAASGDDARQGPVQVAKKNSVGFILPNLEVKFVDPDTGRSLPKNTPGEICVRSQAVMQGYYRKKEETERTIDAKGWLHTGDVGYIDDDGDVFIVDRIKELIKYKGFQVAPAELEAILLSHPSVQDAAVFGLPDEEAGEVPVSCVVRRCGASESEADIMAYVAGRVASYKKLRLLQFVDVIHKSVSGKILRRQLRDEFVSRTKTAAA
>rna-NM_001153005.1
MGDAAIAAVHLHESEEEHIFRSRFPPVAVPDDVTVPEFVLADAEAYADKTALVEAAPGGRSYTYGELVRDVARFARALRSIGVRRGHVVVVALPNLAVYPVVSLGIMSAGAVFSGVNPRAVAAEIKKQVEDSEARLVVADAVAYDKVKDAGVPVIGIGDVARLPGAIGWDELLAMADRAGAPVVALEPAQQSDLCALPYSSGTTGVSKGVMLSHRNLVSSLCSSMFAVGQELVGQVVTLGLMPFFHIYGITGICCATLRHKGTVVVMDRFDLRAFLGALLTHRVMFAPVVPPVMLAMVKSPVADEFDLSGLALRSVMTAAAPLAPDLLAAFERKFPGVQVEEAYGLTEHSCITLTHASGGGEDVGSAVQVAKKKSVGFILPNLEVKFVDPDTGRSLPKNTPGEICVRSQAVMQGYYRKKEETERTIDAAGWLHTGDVGYIDDDGDVFIVDRIKELIKYKGFQVAPAELEAILLSHPSVEDAAVFGLPDEEAGEVPASCVVRRRGAPESEADMMAYVAGRVASYKKLRLLRFVDAIPKSVSGKILRRQLRDEFVKKTAAA
>rna-XM_008680760.3
MITVAAPEAQPQVAAAAAVAAPEETVFRSKLPDIDIPTHLPLHDYCFSRAAEAAGAPCLIAAATGRTYTYAETRLLCRKAAACLHGLGVAQGDRVMLLLQNSVEFVLAFFGASFLGAVTTAANPFCTPQEIHKQFSASGAKVVVTHSAYVAKLRHGAFPRIGTVSGGGVDGNALLTVLTIDGDAADTPEGCLAFWELLTSGDGDALPEVSISPDDPVALPFSSGTTGLPKGVVLTHGGQVTNVAQQVDGANPNLYMREGDVALCVLPLFHIFSLNSVLLCAMRAGAAVMLMPKFEMGAMLEGIQRWRVTVAAVVPPLVLALAKNPALEKYDLSSIRIVLSGAAPLGKDLVDALRARVPQAVFGQGYGMTEAGPVLSMCPAFAKEPAPAKPGSCGTVVRNAELKVVDPDTGLSLGRNLPGEICIRGPQIMKGYLNDPEATARTIDVHGWLHTGDIGYVDDDDEVFIVDRVKELIKFKGFQVPPAELEALLVAHPSIADAAVVPQKDEAAGEVPVAFVVRAADADIAEDAIKEFISKQVVFYKRLHKVYFTPSIPKSASGKILRRELRAKLAAAATA
>rna-NM_001111788.2
MGSVDAAIAVPVPAAEEKAVEEKAVVFRSKLPDIEIDSSMALHTYCFGKMGEVAERACLVDGLTGASYTYAEVESLSRRAASGLRAMGVGKGDVVMSLLRNCPEFAFTFLGAARLGAATTTANPFYTPHEVHRQAEAAGARLIVTEACAVEKVREFAAERGIPVVTVDGRFDGCVEFAELIAAEELEADADIHPDDVVALPYSSGTTGLPKGVMLTHRSLITSVAQQVDGENPNLYFRKDDVVLCLLPLFHIYSLNSVLLAGLRAGSTIVIMRKFDLGALVDLVRRYVITIAPFVPPIVVEIAKSPRVTAGDLASIRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPYPVKSGSCGTVVRNAELKIVDPDTGAALGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHTGDIGYVDDDDEIFIVDRLKEIIKYKGFQVPPAELEALLITHPEIKDAAVVSMNDDLAGEIPVAFIVRTEGSQVTEDEIKQFVAKEVVFYKKIHKVFFTESIPKNPSGKILRKDLRARLAAGVH
>rna-NM_001175023.1
MPKGVMLTHRSLVTSVAQQVDGENPNLYFSKDDVVLCVLPLFHIYSLNSVLLAGLRAGCAIVIMRKFEIGALVELVRAHGVTVAPFVPPIVVEIAKSPRVGAADLASIRMVMSGAAPMGKDLQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFEVKSGSCGTVVRNAELKIVDPDTSASLGRNQPGEICIRGEQIMKGYLNDPEATKNTIDKDGWLHTGDIGYVDDDDEIFIVDRLKEIIKYKGFQVPPAELEALLITHPEIKDAAVVSMKDEVAGEVPVAFIIRSEGSEISENEIKQFVAKEVVFYKRINRVFFTDSIPKNPSGKILRKDLRARLAAGIPSSDNTQSKS
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University