Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Xanthoceras sorbifolium
Species name
Yellow-horn (Xanthoceras sorbifolium) is a species of eudicot in the family Sapindaceae (soapberry family).
Species info
Gene sequence info
Xanthoceras_sorbifolium.4CL.fa
Download
>XS04G13672.1
MTEAGPVLSMCLGFAKEPYPTKSGSCGTVVRNAELKVIDPETGCSLGYNQPGEICIRGPQIMKGYLNDVESTATTIDVEGWLHTGDIGYVDDDDEVFIVDRVKEIIKFKGFQVPPAELEALLINHSSIADAAVVPQKDEVAGEVPVAFVVRSNGFELTEEAIKEYIAKQVVFYKRLHKVYFVHAIPKSPSGKILRKDLRAKLAVAASPIS
>XS04G12455.1
MAPQLNQEEDIIFRSKLPEIYIPNHLPLHSYVFQNISKVDSRPCLISGSTGHVYTYAEVELISRKVASGFNKIGIQQYQVIMVLLPNCPEFVFSFLGASYIGAIATMANPFFMPAEISKQPEASNAKLIITQACHVDKVREFTQEKDVQIVCIDTAPDGCLHFSELSQTEETQLPEVDIHPEDVVALPYSSSTTGLPKGVMLTHQGLVTSVAQQVEGDNPNLYFHSEDVILCVLPMFHVYALNSIMLCGLRVGATILIMQKFEINSLLQLVQKHKVTVAPIVPPIVLAIAKSPDTAKYDLSSIRILKSGAAPLGKELEDAVRAKFPNAILGQKIMMTSGEEFVRMGSDHDDDARDIESEQTPLLIAGDSKRDHWRWIIPILLARRNLISRADKAKTKTDSKRQRDADLEQTEIVEILPSSPQVWIEVHCDGTNDSTDVSDVKLQHANIAQILGDEEHLRSPCISNTLSKAEAPARGFFKSLLKSRNSHIILLLCVSAAMSIGFGINEKGLRTGWQQGVIIILAIIILVVVSLRRHFLHKHSEKHNPLRKMQMMSQVTQAPNKIKLPSQIDKVSIITQIIGLSVSILILVVVFLRFRLGKEHHDSGVPELERKSSMKDFMDIVKRVIMKPSGNVSILTTSLAMLVVRIMEELPLVVTLGILYWYKKALSDRAFAQEPLACVSMGSVTTICTGKTGGLTRQATKAFIDADVNIILISEEDVSVLEAIKIECGLLHNPERMAVEGEVLRRWTDEERMVMVDNISVIGNSLPSDKLLLVQCLKQKGHTVAMVEARANDTPALKEANLGITIGSWSSELARETSDIVVWDGDFNSLLIICKYGRCAYDNIQKYIQFEVTMFLVWALDTVITTVAFGDAPITTIQWFWANLIVAFAGGLGLLTEPPSKELMEKPPVNQTDPFITKAIWRNIITQALFQAAILVTFQFTSKSILHINNKEVSETMVFNIFVLCQVFNLINARKPNRKNVFKGIHQNRWFWVAVIVIVVPQVAFIEIAHILGGNAKLNGGQWGICVLTGMLSLLIDFTAKCISTLFMYCLTGSHLGSAGMCMYGC
>XS06G16438.3
MEALLAHNEEQIFRSRYPAVPVPDVTLPEFVLQDVELYGDKVAFVEAVTGKAYTYSEVARDIRRFAKALRSLGLRKGRVVVVVLPNVAEYGIVALGIMAAGGVFSGANPTAHSSEIKKQVEAADAKLIVTSGPIYEKVKDLDLPVIVLDEERIESAMNWKELLEAADRAGNNFTNNEIHQTDLCALPFSSGTTGMSKGVMLTHRNLVANLCSTLFSVGPEMIGQVTTLGLIPFFHIYGITGICCATLRNKGKVVVMNRFELRTFLNALITQEVTFAPIVPPIILALVKNPIVEEFDLSKLKLKAVMTAAAPLAPELLAAFEKKFPDVQVQEVKDLDLPVIVLDEERIESAMNWKELLEAADRAGNNFTNNEIHQTDLCALPFSSGTTGMSKGVMLTHRNLVANLCSTLFSVGPEMIGQVTTLGLIPFFHIYGITGICCATLRNKGKVVVMNRFELRTFLNALITQEVTFAPIVPPIILALVKNPIVEEFDLSKLKLKAVMTAAAPLAPELLAAFEKKFPDVQVQEVCTLLYINLTQFW*AYGLTEHSCITLTHGDPAIPNGISKKNSVGFILPNLEIKFIDPETGRSLPKNTAGEICVRSQCVMQGLWTD*AQLHHTHTWRPCHTQWHFKEKLSWVHSPQSRNQVYRSRNRSISPQEHRWRNLC*KPMCHARYKLHKY**QKYR*LTSYNHIYVSYFNNEEETARTIDKNGWLHTGDIGCIDDDGDIFIVDRIKELIKYKGFQVTSTMKRKLPGPLTRMGGCILETLDA*MMMEISLSWIASKS*SSTKVFK*DQHVSLLS
>XS08G18978.1
MAPQLNQEEDIIFRSKLPEIYIPNHLPLHSYVFQNISKVDSRPCLINGSTGHVYTYAEVELISRKVASGFNKIGIQQYQVLMVLLPNCPEFVFSFLGASYIGAIATMANPFFMPAEISKQAEASNAKLIITQACHVDKVKEFAQEKDVQIVCIDTAPDGCLHFSELSQTDETQLQEVDIHPEDVVALPYSSGTTGLPKGVMLTHQGLVTSVAQQVDGDNPNLYFHSEDVILCVLPMFHVYALNSIMLCGLRVGATILIMQKFEINSLLQLAQKHKVTVAPIVPPIVLAIAKSPDTDKYDLSSIRILKSGAAPLGKELEDAVRAKFPNAILGQGYGMTEAGPVLAMCLAFAKEPYSIKPGACGTVVRNAEMKIVEPETGKSLPRNQPGEICIRGAQIMKGIWNDRGRACVGNVFGICKGTI*HKTRSLWNSGQKC*NEDS*A*NR*ISAEESAW*DLHQRSSNHERCAIDFIILGYLNDSEATKRTIDQDGWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEAMLLSHPNIRDAAVVGLKDDAAGEVPVAFVVKSNDSQITEDEIKQFISKQIEG*CSWGSSCGICGEIK*FSNN*R*DQAIYFKTGIYIL**LGGVLQENKSCIFH*SNSESSIWQDIKKGFESQISSRISKL
>XS09G20673.1
MEKSGYGRDGIYRSLRPPLVFPKDPNLSMVTFLFRNSFSYESKPALIEADSSSSLTFSEFKSTLIKVSHGFRHLGIRKNDVVLIFAPNSIQFPVCFLGLIAIGAIATTANPLYTVNELSKQVEDSNAKLVVTVPELWDTVKGFNLPVVILGSKEKMSSSALTSNSKSKVVHFHDLVELSGNVSEFPDVSIKQRDTAALLYSSGTTGVSKGVILTHGNFIAASLMITMDQELAGELNSVYLCALPMFHVFGLAVLVYSQLQKGNTVVSMAKFDFEMALRAIEKYRVTHFWVVPPIVLALAKHSLVKKFDLSSLKHIGSGAAPLGKDLMEECSKNIPHAMVLQGYGMTETCGIISVENPRLAVRNSGSAGLLVAGVEAQIISVDTLKPLPPNQLGEIWVRGPNMMQGYFNNKQATILTIDKQGWVHTGDLGYFDENGQLYVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPYPDAEAGEVPVAYVVRSPNSSLTEDDVQNFIAKQIS*C*SW*GPSCICCSLAK*LADRR*CSEFHC*TGNMSCTF*KIKKSNIHKQRSEVSFRENT*ERDDSESTIQNL
>XS12G05504.1
MDAKEDQHEFIFRSKLTDIYIPNHLPLHTYCFENISQFNDRPCIINGPTGDVYTYADVELTSRKVAAGLDKLGIKQGDVVMLLLQNCPQFVFAFLGASYIGAISTTANPFYTPAEIAKQATASKAKLIITQALYAEKVKDFAAESGVRVMTVDSSPDHYQNCLHFQELTEADENDTPAIKINPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGDNPNLYFHKEDVILCVLPLFHIYSLNSVLLCALRVGAAILIMQKFEILTLMELVQKHKVTIAPFVPPIVLSIAKSPDIDMYDLSSIRTVMSGAAPMGKELEDAVRAKLPNAKLGQGYGMTEAGPVLSMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPDSGASLPRNQSGEICIRGSQIMKGVWDDRSRTSTVNVLGICKGTLRDQIRCVRDCGKKCRDEDRRP*FRCLPSSKSIW*DLHQRKPDHERYTYITSSFSSKNICFWYKINYRIICYKFMLPCMCIA*MHTQIQGWEKRDRKEIF*LRYLNDEEATRRTIDKDGWLHTGDIGFIDDDDELFIVDRLKELIKYKGFQVAPAELEAMLIAHPNISDAAVVP*GT*MTRRRQGEP*TKMDGCTQVT*ASLTMMMSYSSLIV*KN*SNTRASKWPQPSSKLC*LPIPTSPMLLSYR*KMRLQEKFLWHSWSDQTVLKSLKMKSSNTSPNR*YSTRELIGYSSQTQFQKLHQAKSCEKT*EQHWLLVCPI
MTEAGPVLSMCLGFAKEPYPTKSGSCGTVVRNAELKVIDPETGCSLGYNQPGEICIRGPQIMKGYLNDVESTATTIDVEGWLHTGDIGYVDDDDEVFIVDRVKEIIKFKGFQVPPAELEALLINHSSIADAAVVPQKDEVAGEVPVAFVVRSNGFELTEEAIKEYIAKQVVFYKRLHKVYFVHAIPKSPSGKILRKDLRAKLAVAASPIS
>XS04G12455.1
MAPQLNQEEDIIFRSKLPEIYIPNHLPLHSYVFQNISKVDSRPCLISGSTGHVYTYAEVELISRKVASGFNKIGIQQYQVIMVLLPNCPEFVFSFLGASYIGAIATMANPFFMPAEISKQPEASNAKLIITQACHVDKVREFTQEKDVQIVCIDTAPDGCLHFSELSQTEETQLPEVDIHPEDVVALPYSSSTTGLPKGVMLTHQGLVTSVAQQVEGDNPNLYFHSEDVILCVLPMFHVYALNSIMLCGLRVGATILIMQKFEINSLLQLVQKHKVTVAPIVPPIVLAIAKSPDTAKYDLSSIRILKSGAAPLGKELEDAVRAKFPNAILGQKIMMTSGEEFVRMGSDHDDDARDIESEQTPLLIAGDSKRDHWRWIIPILLARRNLISRADKAKTKTDSKRQRDADLEQTEIVEILPSSPQVWIEVHCDGTNDSTDVSDVKLQHANIAQILGDEEHLRSPCISNTLSKAEAPARGFFKSLLKSRNSHIILLLCVSAAMSIGFGINEKGLRTGWQQGVIIILAIIILVVVSLRRHFLHKHSEKHNPLRKMQMMSQVTQAPNKIKLPSQIDKVSIITQIIGLSVSILILVVVFLRFRLGKEHHDSGVPELERKSSMKDFMDIVKRVIMKPSGNVSILTTSLAMLVVRIMEELPLVVTLGILYWYKKALSDRAFAQEPLACVSMGSVTTICTGKTGGLTRQATKAFIDADVNIILISEEDVSVLEAIKIECGLLHNPERMAVEGEVLRRWTDEERMVMVDNISVIGNSLPSDKLLLVQCLKQKGHTVAMVEARANDTPALKEANLGITIGSWSSELARETSDIVVWDGDFNSLLIICKYGRCAYDNIQKYIQFEVTMFLVWALDTVITTVAFGDAPITTIQWFWANLIVAFAGGLGLLTEPPSKELMEKPPVNQTDPFITKAIWRNIITQALFQAAILVTFQFTSKSILHINNKEVSETMVFNIFVLCQVFNLINARKPNRKNVFKGIHQNRWFWVAVIVIVVPQVAFIEIAHILGGNAKLNGGQWGICVLTGMLSLLIDFTAKCISTLFMYCLTGSHLGSAGMCMYGC
>XS06G16438.3
MEALLAHNEEQIFRSRYPAVPVPDVTLPEFVLQDVELYGDKVAFVEAVTGKAYTYSEVARDIRRFAKALRSLGLRKGRVVVVVLPNVAEYGIVALGIMAAGGVFSGANPTAHSSEIKKQVEAADAKLIVTSGPIYEKVKDLDLPVIVLDEERIESAMNWKELLEAADRAGNNFTNNEIHQTDLCALPFSSGTTGMSKGVMLTHRNLVANLCSTLFSVGPEMIGQVTTLGLIPFFHIYGITGICCATLRNKGKVVVMNRFELRTFLNALITQEVTFAPIVPPIILALVKNPIVEEFDLSKLKLKAVMTAAAPLAPELLAAFEKKFPDVQVQEVKDLDLPVIVLDEERIESAMNWKELLEAADRAGNNFTNNEIHQTDLCALPFSSGTTGMSKGVMLTHRNLVANLCSTLFSVGPEMIGQVTTLGLIPFFHIYGITGICCATLRNKGKVVVMNRFELRTFLNALITQEVTFAPIVPPIILALVKNPIVEEFDLSKLKLKAVMTAAAPLAPELLAAFEKKFPDVQVQEVCTLLYINLTQFW*AYGLTEHSCITLTHGDPAIPNGISKKNSVGFILPNLEIKFIDPETGRSLPKNTAGEICVRSQCVMQGLWTD*AQLHHTHTWRPCHTQWHFKEKLSWVHSPQSRNQVYRSRNRSISPQEHRWRNLC*KPMCHARYKLHKY**QKYR*LTSYNHIYVSYFNNEEETARTIDKNGWLHTGDIGCIDDDGDIFIVDRIKELIKYKGFQVTSTMKRKLPGPLTRMGGCILETLDA*MMMEISLSWIASKS*SSTKVFK*DQHVSLLS
>XS08G18978.1
MAPQLNQEEDIIFRSKLPEIYIPNHLPLHSYVFQNISKVDSRPCLINGSTGHVYTYAEVELISRKVASGFNKIGIQQYQVLMVLLPNCPEFVFSFLGASYIGAIATMANPFFMPAEISKQAEASNAKLIITQACHVDKVKEFAQEKDVQIVCIDTAPDGCLHFSELSQTDETQLQEVDIHPEDVVALPYSSGTTGLPKGVMLTHQGLVTSVAQQVDGDNPNLYFHSEDVILCVLPMFHVYALNSIMLCGLRVGATILIMQKFEINSLLQLAQKHKVTVAPIVPPIVLAIAKSPDTDKYDLSSIRILKSGAAPLGKELEDAVRAKFPNAILGQGYGMTEAGPVLAMCLAFAKEPYSIKPGACGTVVRNAEMKIVEPETGKSLPRNQPGEICIRGAQIMKGIWNDRGRACVGNVFGICKGTI*HKTRSLWNSGQKC*NEDS*A*NR*ISAEESAW*DLHQRSSNHERCAIDFIILGYLNDSEATKRTIDQDGWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEAMLLSHPNIRDAAVVGLKDDAAGEVPVAFVVKSNDSQITEDEIKQFISKQIEG*CSWGSSCGICGEIK*FSNN*R*DQAIYFKTGIYIL**LGGVLQENKSCIFH*SNSESSIWQDIKKGFESQISSRISKL
>XS09G20673.1
MEKSGYGRDGIYRSLRPPLVFPKDPNLSMVTFLFRNSFSYESKPALIEADSSSSLTFSEFKSTLIKVSHGFRHLGIRKNDVVLIFAPNSIQFPVCFLGLIAIGAIATTANPLYTVNELSKQVEDSNAKLVVTVPELWDTVKGFNLPVVILGSKEKMSSSALTSNSKSKVVHFHDLVELSGNVSEFPDVSIKQRDTAALLYSSGTTGVSKGVILTHGNFIAASLMITMDQELAGELNSVYLCALPMFHVFGLAVLVYSQLQKGNTVVSMAKFDFEMALRAIEKYRVTHFWVVPPIVLALAKHSLVKKFDLSSLKHIGSGAAPLGKDLMEECSKNIPHAMVLQGYGMTETCGIISVENPRLAVRNSGSAGLLVAGVEAQIISVDTLKPLPPNQLGEIWVRGPNMMQGYFNNKQATILTIDKQGWVHTGDLGYFDENGQLYVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPYPDAEAGEVPVAYVVRSPNSSLTEDDVQNFIAKQIS*C*SW*GPSCICCSLAK*LADRR*CSEFHC*TGNMSCTF*KIKKSNIHKQRSEVSFRENT*ERDDSESTIQNL
>XS12G05504.1
MDAKEDQHEFIFRSKLTDIYIPNHLPLHTYCFENISQFNDRPCIINGPTGDVYTYADVELTSRKVAAGLDKLGIKQGDVVMLLLQNCPQFVFAFLGASYIGAISTTANPFYTPAEIAKQATASKAKLIITQALYAEKVKDFAAESGVRVMTVDSSPDHYQNCLHFQELTEADENDTPAIKINPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGDNPNLYFHKEDVILCVLPLFHIYSLNSVLLCALRVGAAILIMQKFEILTLMELVQKHKVTIAPFVPPIVLSIAKSPDIDMYDLSSIRTVMSGAAPMGKELEDAVRAKLPNAKLGQGYGMTEAGPVLSMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPDSGASLPRNQSGEICIRGSQIMKGVWDDRSRTSTVNVLGICKGTLRDQIRCVRDCGKKCRDEDRRP*FRCLPSSKSIW*DLHQRKPDHERYTYITSSFSSKNICFWYKINYRIICYKFMLPCMCIA*MHTQIQGWEKRDRKEIF*LRYLNDEEATRRTIDKDGWLHTGDIGFIDDDDELFIVDRLKELIKYKGFQVAPAELEAMLIAHPNISDAAVVP*GT*MTRRRQGEP*TKMDGCTQVT*ASLTMMMSYSSLIV*KN*SNTRASKWPQPSSKLC*LPIPTSPMLLSYR*KMRLQEKFLWHSWSDQTVLKSLKMKSSNTSPNR*YSTRELIGYSSQTQFQKLHQAKSCEKT*EQHWLLVCPI
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University