Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Wurfbainia villosum
Species name
Species info
Gene sequence info
Wurfbainia_villosum.COMT.fa
Download
>Avi01G000287.t1
MDSNGAAFHLTPEEDEEACVRARQLTTGSVLPMVLKTAIELGLLQMLVDAGPAAALGPDEIAARLTTQNPSAPDMVDRILRLLAANDIVRCAATENGRRKYSPAPICKYLTDNDATSAGSMANLVLMHQDEVMINIWRYLKEAILNGGHPVLAAYGMTTFEYQAGDPRFSKVFNNAMKGISSLVVKHLLRKYNGFDDVRVLVDVGGNVGGNVHMITCFHPHIKGINFDLPHIIADAPPLPGVEHRGGDMFESVPTGDAIFLKLILHDWSDELCVKLLKNCWKSLPEKGKVIVVESVVPAVPESSPTAKAILQLDLSMMAYNVGGKERTEKEFRALAAAGGFHGFDLFPVFADSFVMEFIK
>Avi12G001433.t1
MGSLREEVPEMTPEEDEVACMLAMTLGSASIPPMTLRAAVELGLLEILVKAGYGAKLSPAEIAAQLPTQNPQAAAMVDRILRLLAAYNVVACAVETGADGRVGRKYGAAPACKYLTKNEDGVSMAALVLMNQDKVLMESWYHLAEAVLDGGIPFNKAYGMTAFEYHGTDPRFNRVFNEGMKNHSIIFTKKLLENYHGFEDIQVLVDVGGGVGGTLSMITAKYPRIKGINFDLPHVISEAPAFPGVEHVGGDMFASVPNGDAMFMKWILHDWSDEHCAKILENCWKALPEKGKVMLFECIVPAVPEANLRAQGVLHMDLVMLAHNPGGKERTKEDFEALATQAGFQGFKSTYIYANTYIIEFTK
>Avi12G001434.t1
MSPVGAAVWELTQEEDEAACMYAMQLASASIPPMTLKAAIELGLLEILAKAGSAAKLSAAEIAAQLPTQNPQAATMVDRMLRLLAAYDVVTCAVAGADADADGLPARTYGPAPVCKYLTKNADGVSMAALALMNQDKVLMESWYHLKDAVLDGGIPFNKAYGMTAFEYHGTDPRFNTVFNEGMKNHSIILTKKLLEIYRGFDDVNVLVDVGGGIGATLYMITSKHPNIRGINFDLSHVISEAPPFPGVEHVGGDMFAAVPTADAIFMKWILHDWSDEHCAKLLKNCYSSLPAHGKVIVVECVLPVVPEPTLKSQGVFHIDLIMLAHNPGGKERTEQEFESLAKQAGFAGFKATYIFANTWVMEFTK
>Avi12G000542.t1
MAPPQLSPEEEEQAFCRAHQLSSATVLPMVLRTAIELGLIEMLVEAGPTASLSSEELAARLPTTNPSAADMVDRILRLLAANAVVSCAADGGRRKYTAAPICKYYVQNDDGGTLADVVLLQHDQVLIDTWRYLTGSILNGGHPVTEAYGTSTFEYQGGDPRFNKMFNGAMKGHSTLLMNKLLRRYDGFADVQVLVDVGGNTGSNLRLITSFYPHVRGINFDLPHVVADAPALPRVEHRGGDMFEAVPAGDAIMLKWILHDWSDEHCVKILKNCWKALPAEKGKVVVVEYALPEMPEATPEAMPIFQLDLCMATYNVGGKERTAEEFKALAKEAGFHGFKALPGFAGSWVLEFHQVDRVLLVVVDRFPIKIP
>Avi12G000543.t1
MAPPQLSPEEEEEQAFCRAHQLSSAAVLPMVLRTAIELGLIEMLVEAGPTAALSSDELAARLPTTNPSAADMVERILRLLAANAVVGCAADGGRRKYTAAPICKYLVQNDDGGTLAGVVLLHQDQVMIDTWRYLTGSILIGGHPVTEAYGTSTFEYQGGDPRFNKMFNGAMKGHSTLVMNKLLRRYDGFADVQVLVDVGGNTGSNLRLITSFYPHVRGINFDLPHVVADAPALPRVEHRGGDMFEAVPSGDAIMLKWILHDWSDEHCVKILKNCWKALPAEKGKVVMVEYVLPEAPEATPEAMSIFQLDLCMAAYNVGGKERTAEEFKALAKEAGFHGFKALPGFAGSWVLEFIK
>Avi12G000541.t1
MAPLQLSPEEEEQACCRAHQLSTAAVLPMVLRTAIELGLIEMLIEAGPIAALSSEELAARLPTTNPSAADMVERILRLLAANSVVGFACDGGRRKYTAEPICKYLVRNDDGGTVADLVLLHQDQVMIDTWRYLTGSILNGGHPVMAAYGMTTFEYQGGDPRFNEVFNGAMKGHSMLVMNNVLRRYDGFADVQVLVDVGGNTGGNLRLITSFYPHVRGINFDLPHVVADAPALARVEHRGGDMFEAVPAGDAIMLKLDLCMAAYNVGGKERTAEEFKALAKEAGFHGFNALPVFAGTWALEFIK
>Avi12G000544.t1
MAPPQLSPEEEEQACCRAHQLSSAAILPMVLSTAIELGLLEMLVEAGPTTALSSEELAARLPTTNPSAADMVERILRLLAANAVVGCAADGGCRKYSATPICKYLVQNDDGGTVANLLLLLQDQVLIDTWRYFTGSILNGGHPVMAAYGMTTFEYQGCDPRFNKVFNGAMKGASTLVMNNMLRRYDGFADVQVLVDVGGNTGSNLRLITSFYPHVRGINFDLPHVVADAPALARVEHRGGDMFEAVPSGDAIMLKWILHDWSDEHCVKILKNCWKALPTEKGKVVVVEYVLPAAPEATPETMAIFQLDLCMAAYSVGGKERTAEEFQALAKEAGFHGFNALPVFAGTWVLELIKQI
>Avi02G002061.t1
MAASTGAGDHASSEMAKEARLAMMGLANMISVPMALNAVVRLNVPDAVWQSGLNAPLSAAEILPLLRPPPPASSDPAILQRLLRLLASYGVFAETRCAASGTRRYALTAVGRTLVPFSPGGESYAAYVLQHHQDALVRAWPRIHEAVLDPTGPEPFARANHGVPAYAYYGGDRDANALMQRAMQGVSEPFMETLLDGYGAAGFGGDVQTLVDVGGSSGSCLHMIMQKFPNIKQGINFDLPEVVNAAPPLPGVKHVGGDMFQSVPAGDVIFMKWVLTTWTDEECTSILRNCYKALPEGSGGKVIACEPVLPEETDDSRRTRALLEGDIFVMTIYRTQGRERTEAEFRHLGVAAGFSSCNAVYLDPFYTILEYTK
>Avi05G001469.t1
MLFFKLKSIKLDPLWHFGFVSMDEEAEFARALQICSSCVFPFTIKTAIELRLLDVIVEAESPVAALYPAQIVAQLPAAADNPEAADMVDRLLRLLASYGVVTCTAEAGSRKYSAAPVTKFLIKHGDDGASSMANLALLIQDRVAVAVWDQMKDSVLHGGLPSDNAFGMSMFEQLGSDARLNKVFNDAMGGHSVVFMKQLLRVYRGFSDVDVLVDVGGNAGASLRMITSEHPHLRGINFDLPHVISQAPPIPGVQHVSGDMFEAVPIGDAIFMKWILHDWSDEDCVKILKNCWGALAQNGKVIVAECVLPELPEQTVKAQAVFQLDLIMMASFLGGKERSEKEFKALAMEAGFKGFKVAHRFAANWAVIEFTK
>Avi09G000293.t1
MGSNADAEWQLTPEEDEAACMYAMHLASASIPPMTLKAAIELGLLEILAKAGGPAAKLSSADVAAQLPAHNPHAPAMVDRILRLLAAYGVVTFAVTGAGADGRPELTYGAAPVCKYLTENEDGVSMAALALMIQDKVFMESWYHLKDAVLDGGIPFNRAYGMTAFEYPGTDPRFNAVFNEGMKNHSIILTKKLLDVYRGFDDVNVLVDVGGGLGATLFMITSKHPNIKGINFDLPHVISEAPPFPGVEHVVGDMFAAVPAAGAIFMKWILHDWSDEHCAKLLKNCYGALPAGGKVIVVDGVLPAVPEPTPKAQGVFHSDLIMLAHNPGGKERTEREFESLAKEAGFAGFKATYIFANSWVMEFTKVLC
MDSNGAAFHLTPEEDEEACVRARQLTTGSVLPMVLKTAIELGLLQMLVDAGPAAALGPDEIAARLTTQNPSAPDMVDRILRLLAANDIVRCAATENGRRKYSPAPICKYLTDNDATSAGSMANLVLMHQDEVMINIWRYLKEAILNGGHPVLAAYGMTTFEYQAGDPRFSKVFNNAMKGISSLVVKHLLRKYNGFDDVRVLVDVGGNVGGNVHMITCFHPHIKGINFDLPHIIADAPPLPGVEHRGGDMFESVPTGDAIFLKLILHDWSDELCVKLLKNCWKSLPEKGKVIVVESVVPAVPESSPTAKAILQLDLSMMAYNVGGKERTEKEFRALAAAGGFHGFDLFPVFADSFVMEFIK
>Avi12G001433.t1
MGSLREEVPEMTPEEDEVACMLAMTLGSASIPPMTLRAAVELGLLEILVKAGYGAKLSPAEIAAQLPTQNPQAAAMVDRILRLLAAYNVVACAVETGADGRVGRKYGAAPACKYLTKNEDGVSMAALVLMNQDKVLMESWYHLAEAVLDGGIPFNKAYGMTAFEYHGTDPRFNRVFNEGMKNHSIIFTKKLLENYHGFEDIQVLVDVGGGVGGTLSMITAKYPRIKGINFDLPHVISEAPAFPGVEHVGGDMFASVPNGDAMFMKWILHDWSDEHCAKILENCWKALPEKGKVMLFECIVPAVPEANLRAQGVLHMDLVMLAHNPGGKERTKEDFEALATQAGFQGFKSTYIYANTYIIEFTK
>Avi12G001434.t1
MSPVGAAVWELTQEEDEAACMYAMQLASASIPPMTLKAAIELGLLEILAKAGSAAKLSAAEIAAQLPTQNPQAATMVDRMLRLLAAYDVVTCAVAGADADADGLPARTYGPAPVCKYLTKNADGVSMAALALMNQDKVLMESWYHLKDAVLDGGIPFNKAYGMTAFEYHGTDPRFNTVFNEGMKNHSIILTKKLLEIYRGFDDVNVLVDVGGGIGATLYMITSKHPNIRGINFDLSHVISEAPPFPGVEHVGGDMFAAVPTADAIFMKWILHDWSDEHCAKLLKNCYSSLPAHGKVIVVECVLPVVPEPTLKSQGVFHIDLIMLAHNPGGKERTEQEFESLAKQAGFAGFKATYIFANTWVMEFTK
>Avi12G000542.t1
MAPPQLSPEEEEQAFCRAHQLSSATVLPMVLRTAIELGLIEMLVEAGPTASLSSEELAARLPTTNPSAADMVDRILRLLAANAVVSCAADGGRRKYTAAPICKYYVQNDDGGTLADVVLLQHDQVLIDTWRYLTGSILNGGHPVTEAYGTSTFEYQGGDPRFNKMFNGAMKGHSTLLMNKLLRRYDGFADVQVLVDVGGNTGSNLRLITSFYPHVRGINFDLPHVVADAPALPRVEHRGGDMFEAVPAGDAIMLKWILHDWSDEHCVKILKNCWKALPAEKGKVVVVEYALPEMPEATPEAMPIFQLDLCMATYNVGGKERTAEEFKALAKEAGFHGFKALPGFAGSWVLEFHQVDRVLLVVVDRFPIKIP
>Avi12G000543.t1
MAPPQLSPEEEEEQAFCRAHQLSSAAVLPMVLRTAIELGLIEMLVEAGPTAALSSDELAARLPTTNPSAADMVERILRLLAANAVVGCAADGGRRKYTAAPICKYLVQNDDGGTLAGVVLLHQDQVMIDTWRYLTGSILIGGHPVTEAYGTSTFEYQGGDPRFNKMFNGAMKGHSTLVMNKLLRRYDGFADVQVLVDVGGNTGSNLRLITSFYPHVRGINFDLPHVVADAPALPRVEHRGGDMFEAVPSGDAIMLKWILHDWSDEHCVKILKNCWKALPAEKGKVVMVEYVLPEAPEATPEAMSIFQLDLCMAAYNVGGKERTAEEFKALAKEAGFHGFKALPGFAGSWVLEFIK
>Avi12G000541.t1
MAPLQLSPEEEEQACCRAHQLSTAAVLPMVLRTAIELGLIEMLIEAGPIAALSSEELAARLPTTNPSAADMVERILRLLAANSVVGFACDGGRRKYTAEPICKYLVRNDDGGTVADLVLLHQDQVMIDTWRYLTGSILNGGHPVMAAYGMTTFEYQGGDPRFNEVFNGAMKGHSMLVMNNVLRRYDGFADVQVLVDVGGNTGGNLRLITSFYPHVRGINFDLPHVVADAPALARVEHRGGDMFEAVPAGDAIMLKLDLCMAAYNVGGKERTAEEFKALAKEAGFHGFNALPVFAGTWALEFIK
>Avi12G000544.t1
MAPPQLSPEEEEQACCRAHQLSSAAILPMVLSTAIELGLLEMLVEAGPTTALSSEELAARLPTTNPSAADMVERILRLLAANAVVGCAADGGCRKYSATPICKYLVQNDDGGTVANLLLLLQDQVLIDTWRYFTGSILNGGHPVMAAYGMTTFEYQGCDPRFNKVFNGAMKGASTLVMNNMLRRYDGFADVQVLVDVGGNTGSNLRLITSFYPHVRGINFDLPHVVADAPALARVEHRGGDMFEAVPSGDAIMLKWILHDWSDEHCVKILKNCWKALPTEKGKVVVVEYVLPAAPEATPETMAIFQLDLCMAAYSVGGKERTAEEFQALAKEAGFHGFNALPVFAGTWVLELIKQI
>Avi02G002061.t1
MAASTGAGDHASSEMAKEARLAMMGLANMISVPMALNAVVRLNVPDAVWQSGLNAPLSAAEILPLLRPPPPASSDPAILQRLLRLLASYGVFAETRCAASGTRRYALTAVGRTLVPFSPGGESYAAYVLQHHQDALVRAWPRIHEAVLDPTGPEPFARANHGVPAYAYYGGDRDANALMQRAMQGVSEPFMETLLDGYGAAGFGGDVQTLVDVGGSSGSCLHMIMQKFPNIKQGINFDLPEVVNAAPPLPGVKHVGGDMFQSVPAGDVIFMKWVLTTWTDEECTSILRNCYKALPEGSGGKVIACEPVLPEETDDSRRTRALLEGDIFVMTIYRTQGRERTEAEFRHLGVAAGFSSCNAVYLDPFYTILEYTK
>Avi05G001469.t1
MLFFKLKSIKLDPLWHFGFVSMDEEAEFARALQICSSCVFPFTIKTAIELRLLDVIVEAESPVAALYPAQIVAQLPAAADNPEAADMVDRLLRLLASYGVVTCTAEAGSRKYSAAPVTKFLIKHGDDGASSMANLALLIQDRVAVAVWDQMKDSVLHGGLPSDNAFGMSMFEQLGSDARLNKVFNDAMGGHSVVFMKQLLRVYRGFSDVDVLVDVGGNAGASLRMITSEHPHLRGINFDLPHVISQAPPIPGVQHVSGDMFEAVPIGDAIFMKWILHDWSDEDCVKILKNCWGALAQNGKVIVAECVLPELPEQTVKAQAVFQLDLIMMASFLGGKERSEKEFKALAMEAGFKGFKVAHRFAANWAVIEFTK
>Avi09G000293.t1
MGSNADAEWQLTPEEDEAACMYAMHLASASIPPMTLKAAIELGLLEILAKAGGPAAKLSSADVAAQLPAHNPHAPAMVDRILRLLAAYGVVTFAVTGAGADGRPELTYGAAPVCKYLTENEDGVSMAALALMIQDKVFMESWYHLKDAVLDGGIPFNRAYGMTAFEYPGTDPRFNAVFNEGMKNHSIILTKKLLDVYRGFDDVNVLVDVGGGLGATLFMITSKHPNIKGINFDLPHVISEAPPFPGVEHVVGDMFAAVPAAGAIFMKWILHDWSDEHCAKLLKNCYGALPAGGKVIVVDGVLPAVPEPTPKAQGVFHSDLIMLAHNPGGKERTEREFESLAKEAGFAGFKATYIFANSWVMEFTKVLC
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University